{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:24:12Z","timestamp":1786991052918,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.intimp.2018.10.005","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T14:44:22Z","timestamp":1539182662000},"page":"182-189","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Inhibitory effects of bisdemethoxycurcumin on mast cell-mediated allergic diseases"],"prefix":"10.1016","volume":"65","author":[{"given":"Meng","family":"Fu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuilian","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saihong","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danni","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0005","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/jpc.12806","article-title":"Fifty years of allergy: 1965\u20132015","volume":"51","author":"Campbell","year":"2015","journal-title":"J. Paediatr. Child Health"},{"issue":"3","key":"10.1016\/j.intimp.2018.10.005_bb0010","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4168\/aair.2015.7.3.205","article-title":"Mold allergens in respiratory allergy: from structure to therapy","volume":"7","author":"Twaroch","year":"2015","journal-title":"Allergy, Asthma Immunol. Res."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0015","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.rmed.2011.09.007","article-title":"The role of mast cells in allergic inflammation","volume":"106","author":"Amin","year":"2012","journal-title":"Respir. Med."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0020","first-page":"3","article-title":"Mast cells as orchestrators of the allergic reaction: the IgE-IgE receptor mast cell network","volume":"1","author":"Pawankar","year":"2001","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/978-1-4419-9533-9_7","article-title":"The mechanisms of exocytosis in mast cells","volume":"716","author":"Blank","year":"2011","journal-title":"Adv. Exp. Med. Biol."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0030","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0952-7915(94)90039-6","article-title":"Mast cells: function and contents","volume":"6","author":"Schwartz","year":"1994","journal-title":"Curr. Opin. Immunol."},{"issue":"6760 Suppl","key":"10.1016\/j.intimp.2018.10.005_bb0035","doi-asserted-by":"crossref","first-page":"B24","DOI":"10.1038\/35037021","article-title":"Signalling through the high-affinity IgE receptor Fc epsilonRI","volume":"402","author":"Turner","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2018.10.005_bb0040","first-page":"197","article-title":"Effector roles of IgE antibodies: targeting allergen to the high-affinity IgE receptor for Fc epsilon RI-dependent signaling and antigen presentation","volume":"16","author":"Wilson","year":"2002","journal-title":"Clin. Allergy Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2018.10.005_bb0045","doi-asserted-by":"crossref","first-page":"6285","DOI":"10.4049\/jimmunol.154.12.6285","article-title":"The high affinity IgE receptor (Fc epsilon RI) mediates IgE-dependent allergen presentation","volume":"154","author":"Maurer","year":"1995","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1365-2249.2009.03958.x","article-title":"Histamine H1-receptor antagonists with immunomodulating activities: potential use for modulating T helper type 1 (Th1)\/Th2 cytokine imbalance and inflammatory responses in allergic diseases","volume":"157","author":"Okamoto","year":"2009","journal-title":"Clin. Exp. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2018.10.005_bb0055","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1517\/14656566.5.8.1807","article-title":"A review of the second-generation antihistamine ebastine for the treatment of allergic disorders","volume":"5","author":"Van Cauwenberge","year":"2004","journal-title":"Expert. Opin. Pharmacother."},{"issue":"2","key":"10.1016\/j.intimp.2018.10.005_bb0060","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2174\/1568010023344733","article-title":"Mechanisms of antihistamines and mast cell stabilizers in ocular allergic inflammation","volume":"1","author":"Cook","year":"2002","journal-title":"Curr. Drug. Targets. Inflamm. Allergy."},{"issue":"3","key":"10.1016\/j.intimp.2018.10.005_bb0065","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2174\/1568010023344625","article-title":"Treatment of allergic rhinitis: H1-antihistamines and intranasal steroids","volume":"1","author":"Wang","year":"2002","journal-title":"Curr. Drug. Targets. Inflamm. Allergy."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0070","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s12016-010-8206-2","article-title":"Intranasal steroids in the treatment of allergy-induced rhinorrhea","volume":"41","author":"Nathan","year":"2011","journal-title":"Clin. Rev. Allergy Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0075","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/bph.12138","article-title":"Twenty-first century mast cell stabilizers","volume":"170","author":"Finn","year":"2013","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0080","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ejphar.2015.05.071","article-title":"Mast cell stabilisers","volume":"778","author":"Zhang","year":"2016","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0085","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jep.2015.08.038","article-title":"Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type 1\/type 2 helper T cells (Th1\/Th2) balance in a mouse model of food allergy","volume":"175","author":"Shin","year":"2015","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"10.1016\/j.intimp.2018.10.005_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132467","article-title":"Curcumin ingestion inhibits mastocytosis and suppresses intestinal anaphylaxis in a murine model of food allergy","volume":"10","author":"Kinney","year":"2015","journal-title":"PLoS One"},{"issue":"1\u20132","key":"10.1016\/j.intimp.2018.10.005_bb0095","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cellimm.2015.09.010","article-title":"Anti-inflammatory effect of curcumin on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse","volume":"298","author":"Zhang","year":"2015","journal-title":"Cell. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0100","first-page":"630","article-title":"MAPKs and NFkappaB pathway inhibitory effect of bisdemethoxycurcumin on phorbol-12-myristate-13-acetate and A23187-induced inflammation in human mast cells","volume":"17","author":"Kong","year":"2017","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0105","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.intimp.2013.05.013","article-title":"Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells","volume":"17","author":"Yoo","year":"2013","journal-title":"Int. Immunopharmacol."},{"issue":"9\u201311","key":"10.1016\/j.intimp.2018.10.005_bb0110","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.lfs.2013.07.019","article-title":"Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells","volume":"93","author":"Chung","year":"2013","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0115","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/aps.2016.112","article-title":"2-Hydroxy-3-methoxybenzoic acid attenuates mast cell-mediated allergic reaction in mice via modulation of the FcepsilonRI signaling pathway","volume":"38","author":"Kim","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.intimp.2018.10.005_bb0120","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.taap.2017.02.002","article-title":"Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis","volume":"319","author":"Tan","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0125","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jep.2016.07.032","article-title":"Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells","volume":"192","author":"Chong","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"1\u20133","key":"10.1016\/j.intimp.2018.10.005_bb0130","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ejphar.2013.08.045","article-title":"Evaluation of the effect of kaempferol in a murine allergic rhinitis model","volume":"718","author":"Oh","year":"2013","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2018.10.005_bb0135","first-page":"308","article-title":"H2-Eb1 expression is upregulated in the nasal mucosa of allergic rhinitis [J]","volume":"32","author":"Zhang","year":"2014","journal-title":"Asian Pac. J. Allergy Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2018.10.005_bb0140","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.3109\/13880201003677827","article-title":"Potential of Baliospermum montanum against compound 48\/80-induced systemic anaphylaxis","volume":"48","author":"Venkatesh","year":"2010","journal-title":"Pharm. Biol."},{"issue":"3","key":"10.1016\/j.intimp.2018.10.005_bb0145","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/nri1782","article-title":"Integrated signalling pathways for mast-cell activation","volume":"6","author":"Gilfillan","year":"2006","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2018.10.005_bb0150","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.4049\/jimmunol.162.4.2243","article-title":"The role of actin microfilaments in the down-regulation of the degranulation response in RBL-2H3 mast cells","volume":"162","author":"Frigeri","year":"1999","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2018.10.005_bb0155","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1242\/jcs.113.6.1009","article-title":"Interactions between Fc(epsilon) RI and lipid raft components are regulated by the actin cytoskeleton","volume":"113","author":"Holowka","year":"2000","journal-title":"J. Cell Sci."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0160","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1083\/jcb.200501111","article-title":"Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane","volume":"170","author":"Nishida","year":"2005","journal-title":"J. Cell Biol."},{"issue":"2","key":"10.1016\/j.intimp.2018.10.005_bb0165","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/ncb1527","article-title":"Control of local actin assembly by membrane fusion-dependent compartment mixing","volume":"9","author":"Yu","year":"2007","journal-title":"Nat. Cell Biol."},{"issue":"22","key":"10.1016\/j.intimp.2018.10.005_bb0170","doi-asserted-by":"crossref","first-page":"5891","DOI":"10.1016\/j.bmc.2004.08.027","article-title":"Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells","volume":"12","author":"Matsuda","year":"2004","journal-title":"Bioorg. Med. Chem."},{"issue":"1","key":"10.1016\/j.intimp.2018.10.005_bb0175","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.intimp.2013.04.025","article-title":"Therapeutic potential of curcumin in experimentally induced allergic rhinitis in guinea pigs","volume":"17","author":"Thakare","year":"2013","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0180","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.intimp.2017.05.030","article-title":"Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis","volume":"49","author":"Fu","year":"2017","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2018.10.005_bb0185","doi-asserted-by":"crossref","DOI":"10.2174\/138161282006140220120640","article-title":"Immunomodulating and anti-allergic effects of Negroamaro and Koshu Vitis vinifera fermented grape marc (FGM)","volume":"20","author":"Marzulli","year":"2014","journal-title":"Curr. Pharm. Des."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918308130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918308130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T17:44:58Z","timestamp":1693935898000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576918308130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":37,"alternative-id":["S1567576918308130"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2018.10.005","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibitory effects of bisdemethoxycurcumin on mast cell-mediated allergic diseases","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2018.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}