{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T14:12:35Z","timestamp":1777817555466,"version":"3.51.4"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470609"],"award-info":[{"award-number":["81470609"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81700800"],"award-info":[{"award-number":["81700800"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870632"],"award-info":[{"award-number":["81870632"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800800"],"award-info":[{"award-number":["81800800"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81500695"],"award-info":[{"award-number":["81500695"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2013HQ007"],"award-info":[{"award-number":["ZR2013HQ007"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2017MH008"],"award-info":[{"award-number":["ZR2017MH008"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2017BH025"],"award-info":[{"award-number":["ZR2017BH025"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.intimp.2019.02.017","type":"journal-article","created":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T16:31:09Z","timestamp":1550939469000},"page":"101-109","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Celastrol ameliorates Aspergillus fumigatus keratitis via inhibiting LOX-1"],"prefix":"10.1016","volume":"70","author":[{"given":"Qiaoqiao","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xudong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiqiu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/aos.12440","article-title":"Incidence and clinical characteristics of fungal keratitis in a danish population from 2000 to 2013","volume":"93","author":"Nielsen","year":"2015","journal-title":"Acta Ophthalmol."},{"issue":"4","key":"10.1016\/j.intimp.2019.02.017_bb0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/ICU.0000000000000272","article-title":"Update on fungal keratitis","volume":"27","author":"Garg","year":"2016","journal-title":"Curr. Opin. Ophthalmol."},{"issue":"6","key":"10.1016\/j.intimp.2019.02.017_bb0015","first-page":"698","article-title":"Effect of corneal graft diameter on therapeutic penetrating keratoplasty for fungal keratitis","volume":"5","author":"Li","year":"2012","journal-title":"Int. J. Ophthalmol."},{"issue":"10","key":"10.1016\/j.intimp.2019.02.017_bb0020","first-page":"Dd01","article-title":"Keratomycosis: etiology, risk factors and differential diagnosis- a mini review on trichophyton spp.","volume":"8","author":"Sharma","year":"2014","journal-title":"J. Clin. Diagn. Res."},{"issue":"11","key":"10.1016\/j.intimp.2019.02.017_bb0025","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/j.ophtha.2006.05.035","article-title":"Spectrum of fungal keratitis in north China","volume":"113","author":"Xie","year":"2006","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.intimp.2019.02.017_bb0030","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nrmicro.2017.90","article-title":"Aspergillus fumigatus morphology and dynamic host interactions","volume":"15","author":"van de Veerdonk","year":"2017","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0035","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2567.2012.03556.x","article-title":"Pattern-recognition receptors in human eosinophils","volume":"136","author":"Kvarnhammar","year":"2012","journal-title":"Immunology"},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0040","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4161\/viru.1.1.10228","article-title":"Fungal pathogen recognition by scavenger receptors in nematodes and mammals","volume":"1","author":"Means","year":"2010","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0045","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cardiores.2005.09.006","article-title":"Lectin-like, oxidized low-density lipoprotein receptor-1 (lox-1): a critical player in the development of atherosclerosis and related disorders","volume":"69","author":"Mehta","year":"2006","journal-title":"Cardiovasc. Res."},{"issue":"1\u20132","key":"10.1016\/j.intimp.2019.02.017_bb0050","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0014-5793(98)01414-8","article-title":"Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: upregulated expression by tnf-alpha","volume":"440","author":"Moriwaki","year":"1998","journal-title":"FEBS Lett."},{"issue":"6","key":"10.1016\/j.intimp.2019.02.017_bb0055","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1167\/iovs.14-15989","article-title":"The role of lox-1 in innate immunity to aspergillus fumigatus in corneal epithelial cells","volume":"56","author":"Li","year":"2015","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"9","key":"10.1016\/j.intimp.2019.02.017_bb0060","first-page":"1245","article-title":"The role of lox-1 on innate immunity against Aspergillus keratitis in mice","volume":"9","author":"He","year":"2016","journal-title":"Int. J. Ophthalmol."},{"issue":"12","key":"10.1016\/j.intimp.2019.02.017_bb0065","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1097\/ICO.0000000000001756","article-title":"Fenretinide inhibits neutrophil recruitment and il-1beta production in Aspergillus fumigatus keratitis","volume":"37","author":"Zhao","year":"2018","journal-title":"Cornea"},{"issue":"6","key":"10.1016\/j.intimp.2019.02.017_bb0070","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.17219\/acem\/50572","article-title":"Mycotic infections of the eye","volume":"24","author":"Slowik","year":"2015","journal-title":"Adv. Clin. Exp. Med."},{"key":"10.1016\/j.intimp.2019.02.017_bb0075","article-title":"Medical interventions for fungal keratitis","volume":"4","author":"FlorCruz","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.intimp.2019.02.017_bb0080","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.2147\/OPTH.S92176","article-title":"Outcome of therapeutic penetrating keratoplasty in a tertiary eye care center in Nepal","volume":"9","author":"Bajracharya","year":"2015","journal-title":"Clin. Ophthalmol."},{"issue":"4","key":"10.1016\/j.intimp.2019.02.017_bb0085","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1167\/iovs.14-15982","article-title":"Inhibition of corneal inflammation by the resolvin e1","volume":"56","author":"Lee","year":"2015","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.intimp.2019.02.017_bb0090","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fmed.2017.00069","article-title":"Celastrol: a spectrum of treatment opportunities in chronic diseases","volume":"4","author":"Cascao","year":"2017","journal-title":"Front. Med. (Lausanne)"},{"issue":"9","key":"10.1016\/j.intimp.2019.02.017_bb0095","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1365-2362.2009.02186.x","article-title":"Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from celastrus regelii","volume":"39","author":"Kim","year":"2009","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.intimp.2019.02.017_bb0100","doi-asserted-by":"crossref","first-page":"e1604","DOI":"10.1038\/cddis.2014.543","article-title":"Celastrol induces apoptosis and autophagy via the ros\/jnk signaling pathway in human osteosarcoma cells: an in vitro and in vivo study","volume":"6","author":"Li","year":"2015","journal-title":"Cell Death Dis."},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0105","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1080\/08923973.2018.1440591","article-title":"In vitro immunomodulatory activity of celastrol against influenza a virus infection","volume":"40","author":"Khalili","year":"2018","journal-title":"Immunopharmacol. Immunotoxicol."},{"issue":"6","key":"10.1016\/j.intimp.2019.02.017_bb0110","doi-asserted-by":"crossref","first-page":"e65477","DOI":"10.1371\/journal.pone.0065477","article-title":"Celastrol prevents atherosclerosis via inhibiting lox-1 and oxidative stress","volume":"8","author":"Gu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2019.02.017_bb0115","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12974-016-0516-8","article-title":"Celastrol protects mouse retinas from bright light-induced degeneration through inhibition of oxidative stress and inflammation","volume":"13","author":"Bian","year":"2016","journal-title":"J. Neuroinflammation"},{"issue":"11","key":"10.1016\/j.intimp.2019.02.017_bb0120","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1021\/acschembio.6b00666","article-title":"Inhibition of the flavin-dependent monooxygenase siderophore a (sida) blocks siderophore biosynthesis and aspergillus fumigatus growth","volume":"11","author":"Martin Del Campo","year":"2016","journal-title":"ACS Chem. Biol."},{"issue":"5","key":"10.1016\/j.intimp.2019.02.017_bb0125","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1167\/iovs.07-1237","article-title":"Potential role of macrophages in experimental keratomycosis","volume":"50","author":"Hu","year":"2009","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0130","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1167\/iovs.17-21887","article-title":"Aspergillus fumigatus increased par-2 expression and elevated proinflammatory cytokines expression through the pathway of par-2\/erk1\/2 in cornea","volume":"59","author":"Niu","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0135","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1167\/iovs.02-0446","article-title":"Experimental keratomycosis in a mouse model","volume":"44","author":"Wu","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"9","key":"10.1016\/j.intimp.2019.02.017_bb0140","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137423","article-title":"Indoleamine 2,3-dioxygenase is involved in the inflammation response of corneal epithelial cells to aspergillus fumigatus infections","volume":"10","author":"Jiang","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.intimp.2019.02.017_bb0145","first-page":"548","article-title":"Boxb mediate balb\/c mice corneal inflammation through a tlr4\/myd88-dependent signaling pathway in aspergillus fumigatus keratitis","volume":"11","author":"Liu","year":"2018","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.intimp.2019.02.017_bb0150","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.intimp.2018.08.003","article-title":"Interaction of mannose binding lectin and other pattern recognition receptors in human corneal epithelial cells during aspergillus fumigatus infection","volume":"63","author":"Peng","year":"2018","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.intimp.2019.02.017_bb0155","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.ophtha.2010.09.011","article-title":"Clinical and microbiological characteristics of fungal keratitis in the United States, 2001\u20132007: a multicenter study","volume":"118","author":"Keay","year":"2011","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150114","article-title":"Inhibition of trem-1 and dectin-1 alleviates the severity of fungal keratitis by modulating innate immune responses","volume":"11","author":"Zhong","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.intimp.2019.02.017_bb0165","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/mi.2009.130","article-title":"Intranasally delivered sirna targeting pi3k\/akt\/mtor inflammatory pathways protects from aspergillosis","volume":"3","author":"Bonifazi","year":"2010","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.intimp.2019.02.017_bb0170","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fphar.2018.00104","article-title":"A mechanistic overview of triptolide and celastrol, natural products from Tripterygium wilfordii hook f","volume":"9","author":"Chen","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2019.02.017_bb0175","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cbi.2013.12.007","article-title":"Celastrol ameliorates murine colitis via modulating oxidative stress, inflammatory cytokines and intestinal homeostasis","volume":"210","author":"Shaker","year":"2014","journal-title":"Chem. Biol. Interact."},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0180","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.intimp.2015.03.033","article-title":"Celastrol ameliorates experimental colitis in il-10 deficient mice via the up-regulation of autophagy","volume":"26","author":"Zhao","year":"2015","journal-title":"Int. Immunopharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2019.02.017_bb0185","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1167\/iovs.11-8869","article-title":"Important role of epiregulin in inflammatory responses during corneal epithelial wound healing","volume":"53","author":"Zhang","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"10","key":"10.1016\/j.intimp.2019.02.017_bb0190","first-page":"1217","article-title":"Polymorphonuclear neutrophils delay corneal epithelial wound healing in vitro","volume":"25","author":"Wagoner","year":"1984","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0195","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1128\/IAI.24.3.948-952.1979","article-title":"Experimental bacterial keratitis in neutropenic guinea pigs: polymorphonuclear leukocytes in corneal host defense","volume":"24","author":"Chusid","year":"1979","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0200","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/icb.2011.49","article-title":"Toll-like receptor 2 sirna suppresses corneal inflammation and attenuates aspergillus fumigatus keratitis in rats","volume":"90","author":"Guo","year":"2012","journal-title":"Immunol. Cell Biol."},{"issue":"8","key":"10.1016\/j.intimp.2019.02.017_bb0205","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.18632\/aging.101513","article-title":"Sirt6 deficiency impairs corneal epithelial wound healing","volume":"10","author":"Hu","year":"2018","journal-title":"Aging (Albany NY)"},{"issue":"1","key":"10.1016\/j.intimp.2019.02.017_bb0210","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0171-2985(84)80143-6","article-title":"Interaction of Aspergillus fumigatus spores and pulmonary alveolar macrophages of rabbits","volume":"166","author":"Kurup","year":"1984","journal-title":"Immunobiology"},{"key":"10.1016\/j.intimp.2019.02.017_bb0215","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ejphar.2017.08.036","article-title":"A new mechanism of inhibition of il-1beta secretion by celastrol through the nlrp3 inflammasome pathway","volume":"814","author":"Xin","year":"2017","journal-title":"Eur. J. Pharmacol."},{"issue":"7","key":"10.1016\/j.intimp.2019.02.017_bb0220","first-page":"2078","article-title":"Celastrol aggravates lps-induced inflammation and injuries of liver and kidney in mice","volume":"10","author":"Wu","year":"2018","journal-title":"Am. J. Transl. Res."},{"issue":"17","key":"10.1016\/j.intimp.2019.02.017_bb0225","doi-asserted-by":"crossref","first-page":"5229","DOI":"10.1016\/j.bmc.2012.06.050","article-title":"Suppression of autoimmune arthritis by celastrus-derived celastrol through modulation of pro-inflammatory chemokines","volume":"20","author":"Venkatesha","year":"2012","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.intimp.2019.02.017_bb0230","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.etap.2017.02.002","article-title":"The nf-kappab inhibitor celastrol attenuates acute hepatic dysfunction induced by cecal ligation and puncture in rats","volume":"50","author":"El-Tanbouly","year":"2017","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0235","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.vph.2014.06.008","article-title":"Lipopolysaccharide induced lox-1 expression via tlr4\/myd88\/ros activated p38mapk-nf-kappab pathway","volume":"63","author":"Zhao","year":"2014","journal-title":"Vasc. Pharmacol."},{"issue":"5","key":"10.1016\/j.intimp.2019.02.017_bb0240","doi-asserted-by":"crossref","first-page":"735","DOI":"10.3109\/13693780903496591","article-title":"Splenic and lung response to nonlethal systemic Aspergillus fumigatus infection in c57bl\/6 mice","volume":"48","author":"Mirkov","year":"2010","journal-title":"Med. Mycol."},{"issue":"7","key":"10.1016\/j.intimp.2019.02.017_bb0245","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.4049\/jimmunol.1302235","article-title":"Aspergillus and fusarium corneal infections are regulated by th17 cells and il-17-producing neutrophils","volume":"192","author":"Taylor","year":"2014","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2019.02.017_bb0250","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.bbrc.2018.02.163","article-title":"Celastrol mediates th17 and treg cell generation via metabolic signaling","volume":"497","author":"Zhang","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.intimp.2019.02.017_bb0255","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/mi.2013.107","article-title":"Antigen-specific expansion of human regulatory t cells as a major tolerance mechanism against mucosal fungi","volume":"7","author":"Bacher","year":"2014","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.intimp.2019.02.017_bb9500","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1159\/000161070","article-title":"Blockade of LOX-1 prevents endotoxin-induced acute lung inflammation and injury in mice","volume":"1","author":"Zhang","year":"2009","journal-title":"J. Innate Immun."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918312372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576918312372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T12:51:17Z","timestamp":1606567877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576918312372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":52,"alternative-id":["S1567576918312372"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2019.02.017","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Celastrol ameliorates Aspergillus fumigatus keratitis via inhibiting LOX-1","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2019.02.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}