{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T03:35:52Z","timestamp":1768880152846,"version":"3.49.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.intimp.2019.04.043","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T03:23:16Z","timestamp":1558927396000},"page":"459-466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["SETD7 promotes TNF-\u03b1-induced proliferation and migration of airway smooth muscle cells in vitro through enhancing NF-\u03baB\/CD38 signaling"],"prefix":"10.1016","volume":"72","author":[{"given":"Yuanyuan","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiyi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xudong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangxia","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangli","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuzhen","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2019.04.043_bb0005","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1164\/ajrccm.161.5.9903102","article-title":"Asthma. From bronchoconstriction to airways inflammation and remodeling","volume":"161","author":"Bousquet","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.intimp.2019.04.043_bb0010","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/j.1365-2222.2008.02971.x","article-title":"Pathogenesis of asthma","volume":"38","author":"Holgate","year":"2008","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.intimp.2019.04.043_bb0015","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1083\/jcb.201401050","article-title":"The cell biology of asthma","volume":"205","author":"Erle","year":"2014","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0020","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/rr160","article-title":"Autocrine regulation of asthmatic airway inflammation: role of airway smooth muscle","volume":"3","author":"McKay","year":"2002","journal-title":"Respir. Res."},{"key":"10.1016\/j.intimp.2019.04.043_bb0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1513\/pats.200704-051VS","article-title":"Migration of airway smooth muscle cells","volume":"5","author":"Gerthoffer","year":"2008","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.intimp.2019.04.043_bb0030","doi-asserted-by":"crossref","first-page":"383","DOI":"10.4161\/epi.4.6.9450","article-title":"SET7\/9 mediated methylation of non-histone proteins in mammalian cells","volume":"4","author":"Pradhan","year":"2009","journal-title":"Epigenetics"},{"key":"10.1016\/j.intimp.2019.04.043_bb0035","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.4161\/epi.6.9.16069","article-title":"Substrate and product specificities of SET domain methyltransferases","volume":"6","author":"Del Rizzo","year":"2011","journal-title":"Epigenetics"},{"key":"10.1016\/j.intimp.2019.04.043_bb0040","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S1097-2765(01)00405-1","article-title":"Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase","volume":"8","author":"Wang","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.intimp.2019.04.043_bb0045","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.molcel.2007.12.025","article-title":"Methylation of p53 by Set7\/9 mediates p53 acetylation and activity in vivo","volume":"29","author":"Kurash","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.intimp.2019.04.043_bb0050","doi-asserted-by":"crossref","first-page":"462","DOI":"10.18632\/aging.100471","article-title":"Methylation by Set9 modulates FoxO3 stability and transcriptional activity","volume":"4","author":"Calnan","year":"2012","journal-title":"Aging"},{"key":"10.1016\/j.intimp.2019.04.043_bb0055","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nature03117","article-title":"Regulation of p53 activity through lysine methylation","volume":"432","author":"Chuikov","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2019.04.043_bb0060","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1101\/gad.967202","article-title":"Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation","volume":"16","author":"Nishioka","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.intimp.2019.04.043_bb0065","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1096\/fj.15-273540","article-title":"SET7\/9 regulates cancer cell proliferation by influencing beta-catenin stability","volume":"29","author":"Shen","year":"2015","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2019.04.043_bb0070","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.biopha.2018.07.007","article-title":"Inhibition of SETD7 protects cardiomyocytes against hypoxia\/reoxygenation-induced injury through regulating Keap1\/Nrf2 signaling","volume":"106","author":"Dang","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2019.04.043_bb0075","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.actbio.2018.04.033","article-title":"Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds","volume":"73","author":"Yin","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.intimp.2019.04.043_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0149502","article-title":"SETD7 regulates the differentiation of human embryonic stem cells","volume":"11","author":"Castano","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2019.04.043_bb0085","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.devcel.2016.03.002","article-title":"SETD7 controls intestinal regeneration and tumorigenesis by regulating Wnt\/beta-catenin and Hippo\/YAP signaling","volume":"37","author":"Oudhoff","year":"2016","journal-title":"Dev. Cell"},{"key":"10.1016\/j.intimp.2019.04.043_bb0090","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1016\/j.celrep.2016.05.051","article-title":"SET9-mediated regulation of TGF-beta signaling links protein methylation to pulmonary fibrosis","volume":"15","author":"Elkouris","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.intimp.2019.04.043_bb0095","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.4049\/jimmunol.1400583","article-title":"Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway","volume":"194","author":"Han","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0100","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1096\/fasebj.10.12.8903511","article-title":"Human CD38, a cell-surface protein with multiple functions","volume":"10","author":"Mehta","year":"1996","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2019.04.043_bb0105","doi-asserted-by":"crossref","first-page":"328","DOI":"10.2119\/2006-00099.Lund","article-title":"Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity","volume":"12","author":"Lund","year":"2006","journal-title":"Mol. Med."},{"key":"10.1016\/j.intimp.2019.04.043_bb0110","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/s11481-008-9105-7","article-title":"CD38\/cyclic ADP-ribose regulates astrocyte calcium signaling: implications for neuroinflammation and HIV-1-associated dementia","volume":"3","author":"Banerjee","year":"2008","journal-title":"J. NeuroImmune Pharmacol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0115","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1182\/blood-2003-03-0989","article-title":"CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells","volume":"102","author":"Deaglio","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2019.04.043_bb0120","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1007\/s001250050854","article-title":"The CD38-cyclic ADP-ribose signalling system in insulin secretion: molecular basis and clinical implications","volume":"40","author":"Okamoto","year":"1997","journal-title":"Diabetologia"},{"key":"10.1016\/j.intimp.2019.04.043_bb0125","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.pharmthera.2016.12.002","article-title":"CD38 in the pathogenesis of allergic airway disease: potential therapeutic targets","volume":"172","author":"Deshpande","year":"2017","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.intimp.2019.04.043_bb0130","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1139\/cjpp-2014-0410","article-title":"CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models","volume":"93","author":"Guedes","year":"2015","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0135","article-title":"Cyclic ADP-ribose stimulates sarcoplasmic reticulum calcium release in porcine coronary artery smooth muscle","volume":"270","author":"Kannan","year":"1996","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0140","first-page":"C1653","article-title":"Role of cyclic ADP-ribose in the regulation of [Ca2+]i in porcine tracheal smooth muscle","volume":"274","author":"Prakash","year":"1998","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0145","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/j.1365-2222.1991.tb03205.x","article-title":"TNF alpha mRNA expression in allergic inflammation","volume":"21","author":"Ying","year":"1991","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.intimp.2019.04.043_bb0150","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1164\/ajrccm\/145.2_Pt_1.332","article-title":"Tumor necrosis factor causes bronchial hyperresponsiveness in rats","volume":"145","author":"Kips","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.intimp.2019.04.043_bb0155","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1165\/ajrcmb.15.1.8679222","article-title":"Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells","volume":"15","author":"Amrani","year":"1996","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0160","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1111\/j.1365-2222.2009.03238.x","article-title":"Epithelium-derived chemokines induce airway smooth muscle cell migration","volume":"39","author":"Takeda","year":"2009","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.intimp.2019.04.043_bb0165","first-page":"23","article-title":"TNF-alpha induced CD38 expression in human airway smooth muscle cells: role of MAP kinases and transcription factors NF-kappaB and AP-1","volume":"292","author":"Tirumurugaan","year":"2007","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0170","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1096\/fj.05-4585fje","article-title":"Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids","volume":"20","author":"Kang","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2019.04.043_bb0175","first-page":"4","article-title":"CD38-deficient mice have reduced airway hyperresponsiveness following IL-13 challenge","volume":"291","author":"Guedes","year":"2006","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0180","doi-asserted-by":"crossref","first-page":"26771","DOI":"10.1074\/jbc.M802800200","article-title":"Role of the histone H3 lysine 4 methyltransferase, SET7\/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation","volume":"283","author":"Li","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2019.04.043_bb0185","first-page":"30","article-title":"Role of CD38 in TNF-alpha-induced airway hyperresponsiveness","volume":"294","author":"Guedes","year":"2008","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0190","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.imbio.2007.12.002","article-title":"Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness","volume":"213","author":"Jain","year":"2008","journal-title":"Immunobiology"},{"key":"10.1016\/j.intimp.2019.04.043_bb0195","first-page":"L1138","article-title":"Tyrosine kinase-dependent calcium signaling in airway smooth muscle cells","volume":"278","author":"Tolloczko","year":"2000","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.intimp.2019.04.043_bb0200","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1096\/fj.02-0450fje","article-title":"CD38\/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth muscle hyper-responsiveness","volume":"17","author":"Deshpande","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2019.04.043_bb0205","doi-asserted-by":"crossref","first-page":"18972","DOI":"10.1073\/pnas.0910439106","article-title":"Regulation of NF-kappaB activity through lysine monomethylation of p65","volume":"106","author":"Ea","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.intimp.2019.04.043_bb0210","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1365-2222.1994.tb00920.x","article-title":"Attenuation of allergic airway inflammation in IL-4 deficient mice","volume":"24","author":"Brusselle","year":"1994","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.intimp.2019.04.043_bb0215","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1165\/ajrcmb.12.3.7873190","article-title":"Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice","volume":"12","author":"Brusselle","year":"1995","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0220","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1136\/thx.47.12.1050","article-title":"Immune responses to colophony, an agent causing occupational asthma","volume":"47","author":"Cullen","year":"1992","journal-title":"Thorax"},{"key":"10.1016\/j.intimp.2019.04.043_bb0225","article-title":"Increased expression of SETD7 promotes cell proliferation by regulating cell cycle and indicates poor prognosis in hepatocellular carcinoma","volume":"11","author":"Chen","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2019.04.043_bb0230","doi-asserted-by":"crossref","first-page":"9859","DOI":"10.18632\/oncotarget.7126","article-title":"The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer","volume":"7","author":"Zhang","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.intimp.2019.04.043_bb0235","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.207761","article-title":"The methyltransferase SET9 regulates TGFB1 activation of renal fibroblasts via interaction with SMAD3","volume":"131","author":"Shuttleworth","year":"2018","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.intimp.2019.04.043_bb0240","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cyto.2017.04.005","article-title":"Quercus infectoria inhibits Set7\/NF-kappaB inflammatory pathway in macrophages exposed to a diabetic environment","volume":"94","author":"Chokpaisarn","year":"2017","journal-title":"Cytokine"},{"key":"10.1016\/j.intimp.2019.04.043_bb0245","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/emboj.2009.55","article-title":"Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit","volume":"28","author":"Yang","year":"2009","journal-title":"EMBO J."},{"key":"10.1016\/j.intimp.2019.04.043_bb0250","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/aps.2012.161","article-title":"Set9, NF-kappaB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells","volume":"34","author":"Hu","year":"2013","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.intimp.2019.04.043_bb0255","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1124\/mol.104.001040","article-title":"Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway","volume":"66","author":"Tliba","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.intimp.2019.04.043_bb0260","first-page":"20","article-title":"Altered CD38\/cyclic ADP-ribose signaling contributes to the asthmatic phenotype","volume":"289468","author":"Jude","year":"2012","journal-title":"J. Allergy"},{"key":"10.1016\/j.intimp.2019.04.043_bb0265","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1186\/1465-9921-9-26","article-title":"Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone","volume":"9","author":"Tirumurugaan","year":"2008","journal-title":"Respir. Res."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576919303157?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576919303157?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T17:15:42Z","timestamp":1761585342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576919303157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":53,"alternative-id":["S1567576919303157"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2019.04.043","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SETD7 promotes TNF-\u03b1-induced proliferation and migration of airway smooth muscle cells in vitro through enhancing NF-\u03baB\/CD38 signaling","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2019.04.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}