{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:43:09Z","timestamp":1790473389761,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.intimp.2020.106510","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T00:36:16Z","timestamp":1588120576000},"page":"106510","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["ERK is involved in the differentiation and function of dimethyl sulfoxide-induced HL-60 neutrophil-like cells, which mimic inflammatory neutrophils"],"prefix":"10.1016","volume":"84","author":[{"given":"Duo","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Sennari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyue","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Morita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamotsu","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2020.106510_b0005","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.envint.2014.10.005","article-title":"A review on the human health impact of airborne particulate matter","volume":"74","author":"Kim","year":"2015","journal-title":"Environ. Int."},{"issue":"5","key":"10.1016\/j.intimp.2020.106510_b0010","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1039\/C6TX00216A","article-title":"Lipopolysaccharide attached to urban particulate matter 10 suppresses immune responses in splenocytes while particulate matter itself activates NF-kappaB","volume":"5","author":"Song","year":"2016","journal-title":"Toxicol. Res. (Camb.)"},{"issue":"2","key":"10.1016\/j.intimp.2020.106510_b0015","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/jat.3726","article-title":"The toll like receptor 4-myeloid differentiation factor 88 pathway is essential for particulate matter-induced activation of CD4-positive cells","volume":"39","author":"Song","year":"2019","journal-title":"J. Appl. Toxicol. : JAT"},{"key":"10.1016\/j.intimp.2020.106510_b0020","first-page":"1","article-title":"Particulate matter, asian sand dust delays cyclophosphamide-induced type 1 diabetes in NOD mice","author":"Morita","year":"2019","journal-title":"Immunol. Invest."},{"issue":"7","key":"10.1016\/j.intimp.2020.106510_b0025","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1136\/thoraxjnl-2013-204492","article-title":"Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions: a systematic review and meta-analysis","volume":"69","author":"Atkinson","year":"2014","journal-title":"Thorax"},{"issue":"4","key":"10.1016\/j.intimp.2020.106510_b0030","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/jat.3554","article-title":"Lipopolysaccharide levels adherent to PM2.5 play an important role in particulate matter induced-immunosuppressive effects in mouse splenocytes","volume":"38","author":"He","year":"2018","journal-title":"J. Appl. Toxicol. : JAT"},{"key":"10.1016\/j.intimp.2020.106510_b0035","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.intimp.2018.02.020","article-title":"Endocytosis of particulate matter induces cytokine production by neutrophil via toll-like receptor 4","volume":"57","author":"Miyake","year":"2018","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.intimp.2020.106510_b0040","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1182\/blood.V70.5.1233.1233","article-title":"The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression","volume":"70","author":"Collins","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2020.106510_b0045","first-page":"41","article-title":"The HL60 cell line: a model system for studying human myeloid cell differentiation","volume":"9","author":"Birnie","year":"1988","journal-title":"Br. J. Cancer Suppl."},{"issue":"1","key":"10.1016\/j.intimp.2020.106510_b0050","doi-asserted-by":"crossref","first-page":"17406","DOI":"10.1038\/s41598-017-17720-4","article-title":"Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout","volume":"7","author":"MacDonald","year":"2017","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.intimp.2020.106510_b0055","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/imcb.12015","article-title":"The influence of agents differentiating HL-60 cells toward granulocyte-like cells on their ability to release neutrophil extracellular traps","volume":"96","author":"Manda-Handzlik","year":"2018","journal-title":"Immunol. Cell Biol."},{"issue":"9","key":"10.1016\/j.intimp.2020.106510_b0060","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nri3495","article-title":"Mitogen-activated protein kinases in innate immunity","volume":"13","author":"Arthur","year":"2013","journal-title":"Nat. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2020.106510_b0065","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/nri2035","article-title":"MAPK phosphatases\u2013regulating the immune response","volume":"7","author":"Liu","year":"2007","journal-title":"Nat. Rev. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2020.106510_b0070","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1002\/cncr.25711","article-title":"Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia","volume":"117","author":"Ding","year":"2011","journal-title":"Cancer"},{"issue":"14","key":"10.1016\/j.intimp.2020.106510_b0075","first-page":"3163","article-title":"Retinoic acid induced mitogen-activated protein (MAP)\/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest","volume":"58","author":"Yen","year":"1998","journal-title":"Cancer Res."},{"key":"10.1016\/j.intimp.2020.106510_b0080","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.3389\/fimmu.2018.02854","article-title":"Streptococcus suis serotype 2 stimulates neutrophil extracellular traps formation via activation of p38 MAPK and ERK1\/2","volume":"9","author":"Ma","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2020.106510_b0085","doi-asserted-by":"crossref","unstructured":"M. He, T. Ichinose, S. Yoshida, T. Ito, C. He, Y. Yoshida, K. Arashidani, H. Takano, G. Sun, T. Shibamoto, PM2.5-induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells, J. Appl. Toxicol. : JAT 37(10) (2017) 1203-1218.","DOI":"10.1002\/jat.3482"},{"key":"10.1016\/j.intimp.2020.106510_b0090","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3389\/fcimb.2017.00159","article-title":"Influence of microbes on neutrophil life and death","volume":"7","author":"Kobayashi","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"7","key":"10.1016\/j.intimp.2020.106510_b0095","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1182\/blood-2012-01-404046","article-title":"Ly6G ligation blocks recruitment of neutrophils via a beta2-integrin-dependent mechanism","volume":"120","author":"Wang","year":"2012","journal-title":"Blood"},{"issue":"11","key":"10.1016\/j.intimp.2020.106510_b0100","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.nutres.2008.09.007","article-title":"Ribose enhances retinoic acid-induced differentiation of HL-60 cells","volume":"28","author":"Freeman","year":"2008","journal-title":"Nutr. Res."},{"issue":"12","key":"10.1016\/j.intimp.2020.106510_b0105","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/j.leukres.2007.06.011","article-title":"Increased responsiveness to TLR2 and TLR4 ligands during dimethylsulfoxide-induced neutrophil-like differentiation of HL-60 myeloid leukemia cells","volume":"31","author":"Shuto","year":"2007","journal-title":"Leuk. Res."},{"issue":"11","key":"10.1016\/j.intimp.2020.106510_b0110","doi-asserted-by":"crossref","first-page":"13424","DOI":"10.3390\/molecules171113424","article-title":"NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin","volume":"17","author":"Chen","year":"2012","journal-title":"Molecules"},{"issue":"10","key":"10.1016\/j.intimp.2020.106510_b0115","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s00011-017-1070-2","article-title":"Endocytosis is required for exocytosis and priming of respiratory burst activity in human neutrophils","volume":"66","author":"Creed","year":"2017","journal-title":"Inflamm. Res."},{"issue":"6","key":"10.1016\/j.intimp.2020.106510_b0120","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.186","article-title":"Extracellular DNA traps released by acute promyelocytic leukemia cells through autophagy","volume":"7","author":"Ma","year":"2016","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.intimp.2020.106510_b0125","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.micinf.2016.09.003","article-title":"Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes","volume":"19","author":"Dinner","year":"2017","journal-title":"Microbes Infect."},{"issue":"6","key":"10.1016\/j.intimp.2020.106510_b0130","doi-asserted-by":"crossref","first-page":"675","DOI":"10.2174\/138945006777435263","article-title":"Cytokines as targets in chronic obstructive pulmonary disease","volume":"7","author":"Chung","year":"2006","journal-title":"Curr. Drug Targets"},{"issue":"7","key":"10.1016\/j.intimp.2020.106510_b0135","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.yexcr.2010.01.007","article-title":"Up- or downregulation of tescalcin in HL-60 cells is associated with their differentiation to either granulocytic or macrophage-like lineage","volume":"316","author":"Levay","year":"2010","journal-title":"Exp. Cell Res."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576920302137?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576920302137?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T19:24:12Z","timestamp":1754508252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576920302137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":27,"alternative-id":["S1567576920302137"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2020.106510","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ERK is involved in the differentiation and function of dimethyl sulfoxide-induced HL-60 neutrophil-like cells, which mimic inflammatory neutrophils","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2020.106510","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106510"}}