{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:10:47Z","timestamp":1790892647481,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170730"],"award-info":[{"award-number":["81170730"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273296"],"award-info":[{"award-number":["81273296"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570709"],"award-info":[{"award-number":["81570709"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771741"],"award-info":[{"award-number":["81771741"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007620","name":"Department of Education of Liaoning Province","doi-asserted-by":"publisher","award":["[2014]187"],"award-info":[{"award-number":["[2014]187"]}],"id":[{"id":"10.13039\/501100007620","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFC0907403"],"award-info":[{"award-number":["2017YFC0907403"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013077","name":"National Science and Technology Planning Project","doi-asserted-by":"publisher","award":["2014BA106B02"],"award-info":[{"award-number":["2014BA106B02"]}],"id":[{"id":"10.13039\/501100013077","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.intimp.2021.108507","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T08:47:04Z","timestamp":1641286024000},"page":"108507","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["The expression of anti-protein disulfide isomerase A3 autoantibody is associated with the increased risk of miscarriage in euthyroid women with thyroid autoimmunity"],"prefix":"10.1016","volume":"104","author":[{"given":"Zheng","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyan","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2021.108507_b0005","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1089\/thy.2019.0067","article-title":"Efficacy and Safety of Long-Term Universal Salt Iodization on Thyroid Disorders: Epidemiological Evidence from 31 Provinces of Mainland China","volume":"30","author":"Li","year":"2020","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0010","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1093\/humupd\/dmr024","article-title":"Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review","volume":"17","author":"van den Boogaard","year":"2011","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.intimp.2021.108507_b0015","doi-asserted-by":"crossref","first-page":"d2616","DOI":"10.1136\/bmj.d2616","article-title":"Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence","volume":"342","author":"Thangaratinam","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.intimp.2021.108507_b0020","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1089\/thy.2014.0029","article-title":"Maternal subclinical hypothyroidism, thyroid autoimmunity, and the risk of miscarriage: a prospective cohort study","volume":"24","author":"Liu","year":"2014","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0025","doi-asserted-by":"crossref","unstructured":"Y.L. Lee, H.P. Ng, K.S. Lau, W.M. Liu, W.S. O, W.S. Yeung, A.W. Kung, Increased fetal abortion rate in autoimmune thyroid disease is related to circulating TPO autoantibodies in an autoimmune thyroiditis animal model, Fertil Steril, 91 (2009) 2104-2109.","DOI":"10.1016\/j.fertnstert.2008.07.1704"},{"key":"10.1016\/j.intimp.2021.108507_b0030","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1093\/humrep\/deg210","article-title":"The pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice","volume":"18","author":"Matalon","year":"2003","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.intimp.2021.108507_b0035","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2478\/s11658-011-0022-z","article-title":"ERp57\/GRP58: a protein with multiple functions","volume":"16","author":"Turano","year":"2011","journal-title":"Cell Mol. Biol. Lett."},{"key":"10.1016\/j.intimp.2021.108507_b0040","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.pharmthera.2017.07.011","article-title":"Multifunctional molecule ERp57: from cancer to neurodegenerative diseases","volume":"181","author":"Hettinghouse","year":"2018","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.intimp.2021.108507_b0045","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/exd.14147","article-title":"Vitamin D receptor(s): In the nucleus but also at membranes?","volume":"29","author":"Zmijewski","year":"2020","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.intimp.2021.108507_b0050","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1530\/REP-20-0156","article-title":"PDIA3 regulates trophoblast apoptosis and proliferation in preeclampsia via the MDM2\/p53 pathway","volume":"160","author":"Mo","year":"2020","journal-title":"Reproduction"},{"key":"10.1016\/j.intimp.2021.108507_b0055","doi-asserted-by":"crossref","first-page":"e111687","DOI":"10.1371\/journal.pone.0111687","article-title":"Alteration in endometrial proteins during early- and mid-secretory phases of the cycle in women with unexplained infertility","volume":"9","author":"Manohar","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.intimp.2021.108507_b0060","doi-asserted-by":"crossref","first-page":"113156","DOI":"10.1016\/j.jep.2020.113156","article-title":"Systematic biological and proteomics strategies to explore the regulation mechanism of Shoutai Wan on recurrent spontaneous abortion's biological network","volume":"263","author":"Zeng","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2021.108507_b0065","doi-asserted-by":"crossref","first-page":"e112708","DOI":"10.1371\/journal.pone.0112708","article-title":"Impaired bone formation in Pdia3 deficient mice","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.intimp.2021.108507_b0070","doi-asserted-by":"crossref","first-page":"108350","DOI":"10.1016\/j.clim.2020.108350","article-title":"The role of protein disulphide-isomerase A3 as autoantigen in the pathogenesis of autoimmune thyroiditis and related brain damage in adult mice","volume":"212","author":"Yang","year":"2020","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0075","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s40618-018-0960-7","article-title":"The impact of isolated maternal hypothyroxinemia during the first and second trimester of gestation on pregnancy outcomes: an intervention and prospective cohort study in China","volume":"42","author":"Gong","year":"2019","journal-title":"J. Endocrinol. Invest."},{"key":"10.1016\/j.intimp.2021.108507_b0080","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1089\/thy.2016.0002","article-title":"Reference intervals of thyroid function during pregnancy: self-sequential longitudinal study versus cross-sectional study","volume":"26","author":"Zhang","year":"2016","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0085","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1210\/jc.2015-3519","article-title":"The urine iodine to creatinine as an optimal index of iodine during pregnancy in an iodine adequate area in China","volume":"101","author":"Li","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2021.108507_b0090","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1515\/jpm.2010.132","article-title":"Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region","volume":"39","author":"Breymann","year":"2011","journal-title":"J. Perinat. Med."},{"key":"10.1016\/j.intimp.2021.108507_b0095","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1210\/jc.2013-1674","article-title":"Assessment of thyroid function during first-trimester pregnancy: what is the rational upper limit of serum TSH during the first trimester in Chinese pregnant women?","volume":"99","author":"Li","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2021.108507_b0100","first-page":"1","article-title":"High body mass index is an indicator of maternal hypothyroidism, hypothyroxinemia, and thyroid-peroxidase antibody positivity during early pregnancy","volume":"2015","author":"Han","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.intimp.2021.108507_b0105","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/ncpendmet0846","article-title":"The role of thyroid autoimmunity in fertility and pregnancy","volume":"4","author":"Poppe","year":"2008","journal-title":"Nat. Clin. Pract. Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2021.108507_b0110","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1089\/thy.2011.0087","article-title":"American thyroid association taskforce on thyroid disease during, postpartum, guidelines of the american thyroid association for the diagnosis and management of thyroid disease during pregnancy and postpartum","volume":"21","author":"Stagnaro-Green","year":"2011","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0115","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1089\/thy.2010.0058","article-title":"Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal death","volume":"20","author":"Ashoor","year":"2010","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0120","doi-asserted-by":"crossref","first-page":"432","DOI":"10.31128\/AJGP-01-18-4459","article-title":"Recurrent pregnancy loss: a summary of international evidence-based guidelines and practice","volume":"47","author":"Hong Li","year":"2018","journal-title":"Aust. J. Gen. Pract."},{"issue":"2017","key":"10.1016\/j.intimp.2021.108507_b0125","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1089\/thy.2016.0457","article-title":"Guidelines of the american thyroid association for the diagnosis and management of thyroid disease during pregnancy and the postpartum","volume":"27","author":"Alexander","year":"2017","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0130","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1080\/09513590.2019.1653564","article-title":"Does subclinical hypothyroidism and\/or thyroid autoimmunity influence the IVF\/ICSI outcome? review of the literature","volume":"35","author":"Safarian","year":"2019","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.intimp.2021.108507_b0135","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1001\/jama.1990.03450110068029","article-title":"Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies","volume":"264","author":"Stagnaro-Green","year":"1990","journal-title":"JAMA"},{"key":"10.1016\/j.intimp.2021.108507_b0140","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/j.1471-0528.1993.tb14236.x","article-title":"Antithyroid antibodies underlying thyroid abnormalities and miscarriage or pregnancy induced hypertension","volume":"100","author":"Lejeune","year":"1993","journal-title":"Br. J. Obstet. Gynaecol."},{"key":"10.1016\/j.intimp.2021.108507_b0145","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S0029-7844(97)00283-4","article-title":"Effects of autoantibodies on the course of pregnancy and fetal growth","volume":"90","author":"Iijima","year":"1997","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.intimp.2021.108507_b0150","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1093\/humrep\/15.7.1637","article-title":"Prospective pregnancy outcome in untreated recurrent miscarriers with thyroid autoantibodies","volume":"15","author":"Rushworth","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.intimp.2021.108507_b0155","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1089\/105072501753271743","article-title":"Autoimmune thyroid disease in pregnancy and the postpartum period: relationship to spontaneous abortion","volume":"11","author":"Bagis","year":"2001","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0160","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1093\/humrep\/deh843","article-title":"Levothyroxine treatment in thyroid peroxidase antibody-positive women undergoing assisted reproduction technologies: a prospective study","volume":"20","author":"Negro","year":"2005","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.intimp.2021.108507_b0165","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1477-7827-11-40","article-title":"Measuring thyroid peroxidase antibodies on the day nulliparous women present for management of miscarriage: a descriptive cohort study","volume":"11","author":"Grossmann","year":"2013","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.intimp.2021.108507_b0170","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1186\/s12884-020-03176-4","article-title":"Relationship between anti-thyroid peroxidase antibody positivity and pregnancy-related and fetal outcomes in Euthyroid women: a single-center cohort study","volume":"20","author":"Yuan","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.intimp.2021.108507_b0175","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgz167","article-title":"The impact of thyroid function and TPOAb in the first trimester on pregnancy outcomes: a retrospective study in peking","volume":"105","author":"Zhang","year":"2020","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2021.108507_b0180","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12978-019-0720-y","article-title":"Miscarriage hospitalisations: a national population-based study of incidence and outcomes, 2005\u20132016","volume":"16","author":"San Lazaro Campillo","year":"2019","journal-title":"Reprod. Health"},{"key":"10.1016\/j.intimp.2021.108507_b0185","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aat6114","article-title":"Immune responses at the maternal-fetal interface","volume":"4","author":"Ander","year":"2019","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0190","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.7150\/ijms.48128","article-title":"The exploration of Hashimoto's thyroiditis related miscarriage for better treatment modalities","volume":"17","author":"Min","year":"2020","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.intimp.2021.108507_b0195","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1080\/15548627.2020.1833515","article-title":"Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence","volume":"17","author":"Lu","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.intimp.2021.108507_b0200","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1191\/0961203304lu2009oa","article-title":"Autoantibodies associated with reproductive failure","volume":"13","author":"Shoenfeld","year":"2004","journal-title":"Lupus"},{"key":"10.1016\/j.intimp.2021.108507_b0205","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.clinbiochem.2018.11.017","article-title":"Thyrotropin receptor antibody: a novel risk indicator for pregnancy loss","volume":"64","author":"Li","year":"2019","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.intimp.2021.108507_b0210","doi-asserted-by":"crossref","first-page":"J275","DOI":"10.1016\/j.jaut.2011.11.014","article-title":"Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity","volume":"38","author":"Twig","year":"2012","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.intimp.2021.108507_b0215","first-page":"173","article-title":"The contribution of thyroid autoimmunity to miscarriage in euthyroid women","volume":"107","author":"Lin","year":"2016","journal-title":"Minerva. Med."},{"key":"10.1016\/j.intimp.2021.108507_b0220","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1089\/thy.2019.0456","article-title":"Recurrent pregnancy loss in women with hashimoto's thyroiditis with concurrent non-endocrine autoimmune disorders","volume":"30","author":"Cellini","year":"2020","journal-title":"Thyroid"},{"key":"10.1016\/j.intimp.2021.108507_b0225","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.clim.2019.04.005","article-title":"Pathogenic roles of anti-C1q antibodies in recurrent pregnancy loss","volume":"203","author":"Ohmura","year":"2019","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0230","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jaut.2008.04.023","article-title":"PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients","volume":"31","author":"Fae","year":"2008","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.intimp.2021.108507_b0235","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/molehr\/7.2.113","article-title":"Isolation and identification of sperm membrane antigens recognized by antisperm antibodies, and their possible role in immunological infertility disease","volume":"7","author":"Bohring","year":"2001","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.intimp.2021.108507_b0240","doi-asserted-by":"crossref","first-page":"84","DOI":"10.2133\/dmpk.25.84","article-title":"LKM-1 sera from autoimmune hepatitis patients that recognize ERp57, carboxylesterase 1 and CYP2D6","volume":"25","author":"Komurasaki","year":"2010","journal-title":"Drug Metab. Pharmacokinet."},{"key":"10.1016\/j.intimp.2021.108507_b0245","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.01845","article-title":"Thyroid autoantibodies display both \u201coriginal antigenic sin\u201d and epitope spreading","volume":"8","author":"McLachlan","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0250","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1365-2249.2004.02657.x","article-title":"Antibodies cross-reacting with thyroglobulin and thyroid peroxidase are induced by immunization of rabbits with an immunogenic thyroglobulin 20mer peptide","volume":"138","author":"Thrasyvoulides","year":"2004","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0255","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1365-2249.2006.03246.x","article-title":"Spreading of antibody reactivity to non-thyroid antigens during experimental immunization with human thyroglobulin","volume":"147","author":"Thrasyvoulides","year":"2007","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0260","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1093\/humrep\/der259","article-title":"Interleukin (IL)11 mediates protein secretion and modification in human extravillous trophoblasts","volume":"26","author":"Sonderegger","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.intimp.2021.108507_b0265","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12014-021-09324-y","article-title":"Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature","volume":"18","author":"Khorami Sarvestani","year":"2021","journal-title":"Clin. Proteomics"},{"key":"10.1016\/j.intimp.2021.108507_b0270","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/cmi.2014.53","article-title":"HLA-G-mediated NK cell senescence promotes vascular remodeling: implications for reproduction","volume":"11","author":"Rajagopalan","year":"2014","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0275","doi-asserted-by":"crossref","first-page":"129338","DOI":"10.1016\/j.bbagen.2019.04.003","article-title":"The protein disulfide isomerase family: from proteostasis to pathogenesis","volume":"1864.","author":"Matsusaki","year":"2020","journal-title":"Biochim. Biophys. Acta Gen. Subj"},{"key":"10.1016\/j.intimp.2021.108507_b0280","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1055\/a-0856-1044","article-title":"Can supplementation with vitamin D modify thyroid autoantibodies (anti-TPO Ab, anti-Tg Ab) and thyroid profile (T3, T4, TSH) in Hashimoto's thyroiditis? a double blind, randomized clinical trial","volume":"51","author":"Chahardoli","year":"2019","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.intimp.2021.108507_b0285","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s12020-016-0942-5","article-title":"Vitamin D receptor gene polymorphisms\/haplotypes and serum 25(OH)D3 levels in Hashimoto's thyroiditis","volume":"55","author":"Giovinazzo","year":"2017","journal-title":"Endocrine"},{"key":"10.1016\/j.intimp.2021.108507_b0290","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.3389\/fimmu.2019.02739","article-title":"Immunomodulatory effects of vitamin D in pregnancy and beyond","volume":"10","author":"Cyprian","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2021.108507_b0295","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-019-0526-3","article-title":"Hashimoto\u2019s thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice","volume":"17","author":"Wu","year":"2019","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.intimp.2021.108507_b0300","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/s12276-019-0368-2","article-title":"The role of PDIA3 in myogenesis during muscle regeneration","volume":"52","author":"Wang","year":"2020","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.intimp.2021.108507_b0305","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.coph.2011.05.003","article-title":"Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options","volume":"11","author":"Pignataro","year":"2011","journal-title":"Curr. Opin. Pharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576921011437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576921011437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T17:31:56Z","timestamp":1761586316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576921011437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":61,"alternative-id":["S1567576921011437"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2021.108507","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The expression of anti-protein disulfide isomerase A3 autoantibody is associated with the increased risk of miscarriage in euthyroid women with thyroid autoimmunity","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2021.108507","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108507"}}