{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:15:29Z","timestamp":1778822129101,"version":"3.51.4"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["Z171100001117113"],"award-info":[{"award-number":["Z171100001117113"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873943"],"award-info":[{"award-number":["81873943"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.intimp.2022.108742","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T19:06:12Z","timestamp":1648839972000},"page":"108742","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["The potential role and regulatory mechanism of IL-33\/ST2 axis on T lymphocytes during lipopolysaccharide stimulation or perinatal Listeria infection"],"prefix":"10.1016","volume":"108","author":[{"given":"Chunyun","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaozheng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiqiu","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingyi","family":"Luan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2503-3285","authenticated-orcid":false,"given":"Chenghong","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.intimp.2022.108742_b0005","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nri.2016.95","article-title":"Interleukin-33 in health and disease","volume":"16","author":"Liew","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0010","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1073\/pnas.1115884109","article-title":"IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G","volume":"109","author":"Lefrancais","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"43","key":"10.1016\/j.intimp.2022.108742_b0015","doi-asserted-by":"crossref","first-page":"15502","DOI":"10.1073\/pnas.1410700111","article-title":"Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells","volume":"111","author":"Lefrancais","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0020","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/mi.2012.129","article-title":"Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation","volume":"6","author":"Waern","year":"2013","journal-title":"Mucosal. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2022.108742_b0025","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.4049\/jimmunol.179.4.2051","article-title":"Cutting edge: the ST2 ligand IL-33 potently activates and drives maturation of human mast cells","volume":"179","author":"Allakhverdi","year":"2007","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2022.108742_b0030","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.4049\/jimmunol.1102832","article-title":"IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs","volume":"188","author":"Bartemes","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0035","doi-asserted-by":"crossref","first-page":"9021","DOI":"10.1073\/pnas.0812690106","article-title":"The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1","volume":"106","author":"Cayrol","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2022.108742_b0040","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.immuni.2005.10.004","article-title":"An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor","volume":"23","author":"Dinarello","year":"2005","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.intimp.2022.108742_b0045","first-page":"795","article-title":"Interleukin-33-nuclear factor-\u03baB-CCL2 signaling pathway promotes progression of esophageal squamous cell carcinoma by directing regulatory T cells","volume":"111","author":"Yue","year":"2020","journal-title":"Can. Sci."},{"key":"10.1016\/j.intimp.2022.108742_b0050","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.immuni.2005.09.015","article-title":"IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines","volume":"23","author":"Schmitz","year":"2005","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2022.108742_b0055","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nri2692","article-title":"Disease-associated functions of IL-33: The new kid in the IL-1 family","volume":"10","author":"Liew","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0060","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.it.2012.04.005","article-title":"Interleukin-33 and the function of innate lymphoid cells","volume":"33","author":"Mirchandani","year":"2012","journal-title":"Trends Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0065","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.imbio.2015.11.013","article-title":"Interleukin-33 promoting Th1 lymphocyte differentiation dependents on IL-12","volume":"221","author":"Komai-Koma","year":"2016","journal-title":"Immunobiology"},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0070","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.4049\/jimmunol.166.5.3143","article-title":"Regulation and function of T1\/ST2 expression on CD4+ T cells: induction of type 2 cytokine production by T1\/ST2 cross-linking","volume":"166","author":"Meisel","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0075","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cytogfr.2004.02.004","article-title":"T1\/ST2\u2014an IL-1 receptor-like modulator of immune responses","volume":"15","author":"Trajkovic","year":"2004","journal-title":"Cytokine Growth Factor Rev."},{"issue":"2","key":"10.1016\/j.intimp.2022.108742_b0080","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nri2692","article-title":"Disease-associated functions of IL-33: the new kid in the IL-1 family","volume":"10","author":"Liew","year":"2010","journal-title":"Nat Rev Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0085","article-title":"IL-33 and soluble ST2 are associated with recurrent spontaneous abortion in early pregnancy","volume":"12","author":"Zhao","year":"2021","journal-title":"Front Physiol."},{"issue":"1","key":"10.1016\/j.intimp.2022.108742_b0090","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/nm.4244","article-title":"Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor","volume":"23","author":"Huang","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.intimp.2022.108742_b0095","doi-asserted-by":"crossref","first-page":"962","DOI":"10.3389\/fimmu.2018.00962","article-title":"Interleukin-33 receptor (ST2) deficiency improves the outcome of staphylococcus aureus-induced septic arthritis","volume":"9","author":"Staurengo-Ferrari","year":"2018","journal-title":"Front Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2022.108742_b0100","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.intimp.2013.07.008","article-title":"IL-33 promotes Staphylococcus aureus-infected wound healing in mice","volume":"17","author":"Yin","year":"2013","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2022.108742_b0105","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1096\/fj.15-277822","article-title":"The helminth T2 RNase omega1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism","volume":"30","author":"Hams","year":"2016","journal-title":"FASEB J."},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0110","doi-asserted-by":"crossref","first-page":"e00383","DOI":"10.1128\/mBio.00383-13","article-title":"The IL-33\/ST2 axis is associated with human visceral leishmaniasis and suppresses Th1 responses in the livers of BALB\/c mice infected with Leishmania donovani","volume":"4","author":"Rostan","year":"2013","journal-title":"MBio."},{"key":"10.1016\/j.intimp.2022.108742_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2017.04.011","article-title":"T1\/ST2 deficient mice display protection against Leishmania infantum experimental infection","volume":"172","author":"Khalid","year":"2017","journal-title":"Acta Trop."},{"key":"10.1016\/j.intimp.2022.108742_b0120","doi-asserted-by":"crossref","unstructured":"R.L. Naeye, Maternal floor infarction.Hum Pathol 16(8) (1985) 823-828.","DOI":"10.1016\/S0046-8177(85)80254-9"},{"key":"10.1016\/j.intimp.2022.108742_b0125","doi-asserted-by":"crossref","first-page":"522","DOI":"10.3389\/fimmu.2019.00522","article-title":"Pleiotropic effects of IL-33 on CD4+ T cell differentiation and effector functions","volume":"10","author":"Alvarez","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0130","doi-asserted-by":"crossref","first-page":"1359064","DOI":"10.1155\/2017\/1359064","article-title":"Endogenous IL-33 deficiency exacerbates liver injury and increases hepatic influx of neutrophils in acute murine viral hepatitis","volume":"2017","author":"Carri\u00e8re","year":"2017","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.intimp.2022.108742_b0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003918","article-title":"Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin","volume":"10","author":"Li","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.intimp.2022.108742_b0140","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.intimp.2013.07.008","article-title":"IL-33 promotes Staphylococcus aureus-infected wound healing in mice","volume":"17","author":"Yin","year":"2013","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2022.108742_b0145","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.micinf.2009.02.007","article-title":"ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis","volume":"11","author":"Wieland","year":"2009","journal-title":"Microbes Infect."},{"issue":"3","key":"10.1016\/j.intimp.2022.108742_b0150","first-page":"54","article-title":"Apoptosis: activation and inhibition in health and disease","volume":"6","author":"Solano-G\u00e1lvez","year":"2018","journal-title":"Med. Sci. (Basel)"},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0155","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1053\/j.gastro.2019.07.058","article-title":"Inflammation-induced occludin downregulation limits epithelial apoptosis by suppressing caspase-3 expression","volume":"157","author":"Kuo","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2022.108742_b0160","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1111\/febs.13527","article-title":"Discoveries and controversies in BCL-2 protein-mediated apoptosis","volume":"283","author":"Zheng","year":"2016","journal-title":"FEBS J."},{"key":"10.1016\/j.intimp.2022.108742_b0165","doi-asserted-by":"crossref","first-page":"935","DOI":"10.12688\/f1000research.25607.1","article-title":"The third model of Bax\/Bak activation: a Bcl-2 family feud finally resolved?","volume":"9","author":"Luo","year":"2020","journal-title":"F1000Research"},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0170","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nrm2153","article-title":"The apoptosome: signalling platform of cell death","volume":"8","author":"Riedl","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.intimp.2022.108742_b0175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nri1568","article-title":"The role of BH3-only proteins in the immune system","volume":"5","author":"Strasser","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0180","doi-asserted-by":"crossref","unstructured":"Koichiro Sueyoshi, Carola Ledderose, Yong Shen, Albert H Lee, Nathan I Shapiro, Wolfgang G Junger, Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors. J. Biol. Chem. 294 (16) (2019) 6283\u20136293.","DOI":"10.1074\/jbc.RA118.007188"},{"key":"10.1016\/j.intimp.2022.108742_b0185","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1158\/0008-5472.CAN-13-2729","article-title":"Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity","volume":"74","author":"Villarreal","year":"2014","journal-title":"Can. Res."},{"key":"10.1016\/j.intimp.2022.108742_b0190","article-title":"IL-33 induces IL-9 production in human CD4+ T cells and basophils","volume":"6","author":"Blom","year":"2016","journal-title":"PLoS ONE"},{"issue":"7","key":"10.1016\/j.intimp.2022.108742_b0195","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1056\/NEJMoa1907462","article-title":"Outbreak of listeriosis in South Africa associated with processed meat","volume":"382","author":"Thomas","year":"2020","journal-title":"N Engl. J. Med."},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0200","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S1473-3099(16)30521-7","article-title":"Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study","volume":"17","author":"Charlier","year":"2017","journal-title":"Lancet Infect Dis."},{"issue":"1","key":"10.1016\/j.intimp.2022.108742_b0205","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1080\/21505594.2021.1975526","article-title":"Pathogenicity and virulence of Listeria monocytogenes: a trip from environmental to medical microbiology","volume":"12","author":"Quereda","year":"2021","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.intimp.2022.108742_b0210","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.4102\/ojvr.v87i1.1869","article-title":"A review of Listeria monocytogenes from meat and meat products: epidemiology, virulence factors, antimicrobial resistance and diagnosis","volume":"87","author":"Matle","year":"2020","journal-title":"Onderstepoort. J. Vet Res."},{"issue":"5","key":"10.1016\/j.intimp.2022.108742_b0215","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3390\/toxins12050297","article-title":"Potential roles and functions of listerial virulence factors during brain entry","volume":"12","author":"Banovi\u0107","year":"2020","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.intimp.2022.108742_b0220","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.3389\/fimmu.2020.01666","article-title":"Host lipid rafts as the gates for listeria monocytogenes infection: a mini-review","volume":"11","author":"Tsai","year":"2020","journal-title":"Front Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2020.104276","article-title":"Extracellular vesicles released by myeloid-derived suppressor cells from pregnant women modulate adaptive immune responses","volume":"361","author":"Dietz","year":"2021","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.intimp.2022.108742_b0230","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/978-1-60761-869-0_25","article-title":"Pregnancy: tolerance and suppression of immune responses","volume":"677","author":"Leber","year":"2011","journal-title":"Methods Mol. Biol."},{"issue":"11","key":"10.1016\/j.intimp.2022.108742_b0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006736","article-title":"Progesterone impairs antigen-non-specific immune protection by CD8 T memory cells via interferon-\u03b3 gene hypermethylation","volume":"13","author":"Yao","year":"2017","journal-title":"PLoS Pathog."},{"issue":"11","key":"10.1016\/j.intimp.2022.108742_b0240","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/j.healun.2016.08.009","article-title":"Possible progesterone-induced gestational activation of chromosomally integrated human herpesvirus 6B and transplacental transmission of activated human herpesvirus 6B","volume":"35","author":"Das","year":"2016","journal-title":"J. Heart Lung Transplant."},{"issue":"10","key":"10.1016\/j.intimp.2022.108742_b0245","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/S1473-3099(15)00302-3","article-title":"Pregnancy-associated listeriosis: many beliefs, few facts","volume":"15","author":"Elinav","year":"2015","journal-title":"Lancet. Infect Dis."},{"key":"10.1016\/j.intimp.2022.108742_b0250","unstructured":"Green, E.S., Moldenhauer, L.M., McColl, S.R., Robertson, S.A., 2018. Reduced progesterone signalling at implantation compromises Treg cell tolerance and impairs fetal growth and viability in later gestation. Clinical Endocrinology. 89 (37) (2018) Supplement 1."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576922002260?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576922002260?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:51:17Z","timestamp":1778820677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576922002260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":50,"alternative-id":["S1567576922002260"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2022.108742","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The potential role and regulatory mechanism of IL-33\/ST2 axis on T lymphocytes during lipopolysaccharide stimulation or perinatal Listeria infection","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2022.108742","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108742"}}