{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T07:20:25Z","timestamp":1784013625448,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.intimp.2023.110273","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T11:26:50Z","timestamp":1684150010000},"page":"110273","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["The use of orthokine therapy for the treatment of post refractive surgery corneal ulcer, a case report"],"prefix":"10.1016","volume":"120","author":[{"given":"Kamran","family":"Mansouri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gelavizh","family":"Rostaminasab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Touraj","family":"Ahmadi Jouybari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9288-7475","authenticated-orcid":false,"given":"Masood","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.intimp.2023.110273_b0005","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1136\/bjo.81.8.622","article-title":"Corneal ulceration in the developing world\u2014a silent epidemic","volume":"81","author":"Whitcher","year":"1997","journal-title":"British Journal of Ophthalmology"},{"issue":"2","key":"10.1016\/j.intimp.2023.110273_b0010","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.oftale.2014.04.012","article-title":"Treatment of corneal ulcers with platelet rich plasma","volume":"89","author":"Acosta","year":"2014","journal-title":"Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)"},{"key":"10.1016\/j.intimp.2023.110273_b0015","first-page":"38","article-title":"Treatment of corneal ulcer complicated in domestic canine, with the complementary use of homeopathy, moxabustion and autologous serum","volume":"11","author":"Neto","year":"2018","journal-title":"IOSR Journal of Agricultural&Veterinary Science"},{"issue":"7","key":"10.1016\/j.intimp.2023.110273_b0020","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/S0161-6420(01)00600-5","article-title":"Infectious keratitis after laser refractive surgery","volume":"108","author":"Kouyoumdjian","year":"2001","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.intimp.2023.110273_b0025","first-page":"121","article-title":"A study on the most prevalent bacterial cause of corneal ulcer and their susceptibility to five common types of ophthalmic antibiotics","volume":"6","author":"Hatami-Mazinani","year":"2020","journal-title":"Trends in Pharmaceutical Sciences."},{"issue":"4","key":"10.1016\/j.intimp.2023.110273_b0030","doi-asserted-by":"crossref","first-page":"379","DOI":"10.13181\/mji.oa.203849","article-title":"Amniotic membrane transplantation for infectious corneal ulcer treatment: A cohort retrospective study","volume":"29","author":"Casalita","year":"2020","journal-title":"Medical Journal of Indonesia."},{"key":"10.1016\/j.intimp.2023.110273_b0035","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s00011-003-1197-1","article-title":"The production of anti-inflammatory cytokines in whole blood by physico-chemical induction","volume":"52","author":"Meijer","year":"2003","journal-title":"Inflammation Research"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0040","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s13104-022-06166-1","article-title":"The therapeutic effects of autologous conditioned serum on knee osteoarthritis: An animal model","volume":"15","author":"Pishgahi","year":"2022","journal-title":"BMC Research Notes"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13018-023-03590-2","article-title":"Efficacy and safety of anti-interleukin-1 therapeutics in the treatment of knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials","volume":"18","author":"Yu","year":"2023","journal-title":"Journal of Orthopaedic Surgery and Research"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13075-019-2003-y","article-title":"Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture","volume":"21","author":"Mehta","year":"2019","journal-title":"Arthritis research & therapy"},{"key":"10.1016\/j.intimp.2023.110273_b0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13075-019-1952-5","article-title":"IL-1\u03b2 receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes","volume":"21","author":"Wang","year":"2019","journal-title":"Arthritis research & therapy"},{"issue":"4","key":"10.1016\/j.intimp.2023.110273_b0060","first-page":"210","article-title":"Comparison of the effect of intra-articular injection of autologous (orthokine) interleukin-1 receptor antagonist (il-1ra) and hyaluronic acid in pain control of knee osteoarthritis","volume":"7","author":"Hashemi","year":"2019","journal-title":"Novelty in Biomedicine."},{"key":"10.1016\/j.intimp.2023.110273_b0065","article-title":"Etiology, risk factor, diagnosis and treatment outcome of fungal corneal ulcer in tertiary care centre","author":"Kumar","year":"2020","journal-title":"IOSR Journal of Dental and Medical Sciences"},{"issue":"4","key":"10.1016\/j.intimp.2023.110273_b0070","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.orthres.2003.12.007","article-title":"Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10","volume":"22","author":"Zhang","year":"2004","journal-title":"Journal of Orthopaedic Research"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0075","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/sj.gt.3301608","article-title":"Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene","volume":"9","author":"Frisbie","year":"2002","journal-title":"Gene therapy"},{"issue":"2","key":"10.1016\/j.intimp.2023.110273_b0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.5604\/01.3001.0014.1167","article-title":"Evaluation of the Effectiveness of Orthokine Therapy: Retrospective Analysis of 1000 Cases","volume":"22","author":"Godek","year":"2020","journal-title":"Ortopedia, Traumatologia, Rehabilitacja"},{"key":"10.1016\/j.intimp.2023.110273_b0085","doi-asserted-by":"crossref","unstructured":"A. Cortegiani, M. Ippolito, G. Spurio, A. Alongi, Use of autologous conditioned serum (ACS-ORTHOKINE) for osteoarthrosic chronic pain and facet joint syndrome: a prospective observational study, (2022), 10.32388\/2PSUHM.","DOI":"10.32388\/2PSUHM"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0090","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s13256-022-03393-9","article-title":"Autologous conditioned serum (Orthokine) injection for treatment of classical trigeminal neuralgia: Results of a single-center case series","volume":"16","author":"Aghamohammadi","year":"2022","journal-title":"Journal of Medical Case Reports"},{"issue":"19","key":"10.1016\/j.intimp.2023.110273_b0095","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.3390\/ani12192717","article-title":"In vitro anti-inflammatory and regenerative effects of autologous conditioned serum from dogs with osteoarthritis","volume":"12","author":"Soontararak","year":"2022","journal-title":"Animals"},{"issue":"1","key":"10.1016\/j.intimp.2023.110273_b0100","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1093\/bmb\/lds016","article-title":"Autologous conditioned serum for the treatment of osteoarthritis and other possible applications in musculoskeletal disorders","volume":"105","author":"Frizziero","year":"2013","journal-title":"Br Med Bull"},{"issue":"2_suppl","key":"10.1016\/j.intimp.2023.110273_b0105","doi-asserted-by":"crossref","DOI":"10.1177\/2325967121S00861","article-title":"The Biologic Approach for Managing Cartilage Injury: Where are We Now\u2122","volume":"11","author":"Evan","year":"2023","journal-title":"Orthopaedic Journal of Sports Medicine"},{"issue":"08","key":"10.1016\/j.intimp.2023.110273_b0110","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1055\/s-2004-821304","article-title":"Treatment of muscle injuries by local administration of autologous conditioned serum: A pilot study on sportsmen with muscle strains","volume":"25","author":"Wright-Carpenter","year":"2004","journal-title":"International journal of sports medicine"},{"issue":"3","key":"10.1016\/j.intimp.2023.110273_b0115","doi-asserted-by":"crossref","first-page":"335","DOI":"10.11152\/mu-1495","volume":"20","author":"Damjanov","year":"2018","journal-title":"Medical ultrasonography"},{"issue":"3","key":"10.1016\/j.intimp.2023.110273_b0120","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.autrev.2004.09.001","article-title":"Safety of tumour necrosis factor and interleukin-1 blocking agents in rheumatic diseases","volume":"4","author":"Botsios","year":"2005","journal-title":"Autoimmunity reviews"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576923005957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576923005957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T18:09:46Z","timestamp":1761588586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576923005957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":24,"alternative-id":["S1567576923005957"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110273","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The use of orthokine therapy for the treatment of post refractive surgery corneal ulcer, a case report","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110273","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110273"}}