{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:45:56Z","timestamp":1790660756138,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020M671561"],"award-info":[{"award-number":["2020M671561"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009156","name":"Nantong Science and Technology Bureau","doi-asserted-by":"publisher","award":["JC2021080"],"award-info":[{"award-number":["JC2021080"]}],"id":[{"id":"10.13039\/501100009156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009156","name":"Nantong Science and Technology Bureau","doi-asserted-by":"publisher","award":["JC12022005"],"award-info":[{"award-number":["JC12022005"]}],"id":[{"id":"10.13039\/501100009156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012493","name":"Jiangsu Province Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020Z130"],"award-info":[{"award-number":["2020Z130"]}],"id":[{"id":"10.13039\/100012493","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012493","name":"Jiangsu Province Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["JS-2019-263"],"award-info":[{"award-number":["JS-2019-263"]}],"id":[{"id":"10.13039\/100012493","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.intimp.2023.110360","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T14:39:53Z","timestamp":1685025593000},"page":"110360","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Upregulation of CD226 on subsets of T cells and NK cells is associated with upregulated adhesion molecules and cytotoxic factors in patients with tuberculosis"],"prefix":"10.1016","volume":"120","author":[{"given":"Yongwei","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangqiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuwen","family":"Fei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6152-220X","authenticated-orcid":false,"given":"Wenxuan","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2882-0599","authenticated-orcid":false,"given":"Junling","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6054-5991","authenticated-orcid":false,"given":"Feifan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8635-5376","authenticated-orcid":false,"given":"Jiahai","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2023.110360_b0005","unstructured":"Global Tuberculosis reports 2021, World Health Organization. (2021)."},{"key":"10.1016\/j.intimp.2023.110360_b0010","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1001\/jama.282.7.677","article-title":"Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project","volume":"282","author":"Dye","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.intimp.2023.110360_b0015","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/s41577-018-0025-3","article-title":"Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection","volume":"18","author":"Simmons","year":"2018","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0020","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/JLB.MA1118-450RR","article-title":"PD-1 modulating Mycobacterium tuberculosis-specific polarized effector memory T cells response in tuberculosis pleurisy","volume":"106","author":"Li","year":"2019","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.intimp.2023.110360_b0025","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.ajpath.2014.11.003","article-title":"LAG3 expression in active Mycobacterium tuberculosis infections","volume":"185","author":"Phillips","year":"2015","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.intimp.2023.110360_b0030","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.cyto.2015.05.012","article-title":"Tim-3 pathway affects NK cell impairment in patients with active tuberculosis","volume":"76","author":"Wang","year":"2015","journal-title":"Cytokine"},{"key":"10.1016\/j.intimp.2023.110360_b0035","doi-asserted-by":"crossref","first-page":"e0158262","DOI":"10.1371\/journal.pone.0158262","article-title":"Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells","volume":"11","author":"Saharia","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2023.110360_b0040","doi-asserted-by":"crossref","first-page":"e0155721","DOI":"10.1128\/spectrum.01557-21","article-title":"CD84 is a Suppressor of T and B Cell Activation during Mycobacterium tuberculosis Pathogenesis","volume":"10","author":"Zheng","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.intimp.2023.110360_b0045","doi-asserted-by":"crossref","unstructured":"S.S. Hassan, J.E. Cho, M. Akram, K.L. Fielding, H.M. Dockrell, J.M. Cliff, Modulation of NKG2D expression in human CD8(+) T cells corresponding with tuberculosis drug cure, PLoS One. 8 (2013) e70063, https:\/\/doi.rog\/10.1371\/journal.pone.0070063.","DOI":"10.1371\/journal.pone.0070063"},{"key":"10.1016\/j.intimp.2023.110360_b0050","doi-asserted-by":"crossref","unstructured":"J.A. Choreno Parra, N. Martinez Zuniga, L.A. Jimenez Zamudio, L.A. Jimenez Alvarez, C. Salinas Lara, and J. Zuniga, Memory of Natural Killer Cells: A New Chance against Mycobacterium tuberculosis?, Front. Immunol. 8 (2017) 967, https:\/\/doi.org\/10.3389\/fimmu.2017.00967.","DOI":"10.3389\/fimmu.2017.00967"},{"key":"10.1016\/j.intimp.2023.110360_b0055","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.3389\/fimmu.2019.01416","article-title":"Natural Killer Cells in the Lungs","volume":"10","author":"Cong","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0060","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1189\/jlb.4A0713-363RR","article-title":"NK cells kill mycobacteria directly by releasing perforin and granulysin","volume":"96","author":"Lu","year":"2014","journal-title":"J. Leukoc Biol."},{"key":"10.1016\/j.intimp.2023.110360_b0065","doi-asserted-by":"crossref","unstructured":"R. Vankayalapati, A. Garg, A. Porgador, D.E. Griffith, P. Klucar, H. Safi, W.M. Girard, D. Cosman, T. Spies, and P.F. Barnes, Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium, J. Immunol. 175 (2005) 4611\u20134617, , A. Garg, P.F. Barnes, A. Porgador, S. Roy, S. Wu, J.S. Nanda, D.E. Griffith, W.M. Girard, N. Rawal, S. Shetty, and R. Vankayalapati, Vimentin expressed on Mycobacterium tuberculosis-infected human monocytes is involved in binding to the NKp46 receptor, J. Immunol. 177 (2006) 6192\u20136198, https:\/\/doi.org\/10.4049\/jimmunol.177.9.6192.","DOI":"10.4049\/jimmunol.177.9.6192"},{"key":"10.1016\/j.intimp.2023.110360_b0070","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1084\/jem.20030788","article-title":"Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule","volume":"198","author":"Bottino","year":"2003","journal-title":"J Exp Med."},{"key":"10.1016\/j.intimp.2023.110360_b0075","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.immuni.2020.09.010","article-title":"CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8(+) T Cells","volume":"53","author":"Braun","year":"2020","journal-title":"Immunity."},{"key":"10.1016\/j.intimp.2023.110360_b0080","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.3389\/fimmu.2018.02341","article-title":"Expression of the Inhibitory Receptor TIGIT Is Up-Regulated Specifically on NK Cells With CD226 Activating Receptor From HIV-Infected Individuals","volume":"9","author":"Yin","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0085","doi-asserted-by":"crossref","first-page":"120","DOI":"10.3389\/fcimb.2020.00120","article-title":"Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions","volume":"10","author":"Harris","year":"2020","journal-title":"Front. Cell Infect. Microbiol."},{"key":"10.1016\/j.intimp.2023.110360_b0090","doi-asserted-by":"crossref","first-page":"6102","DOI":"10.4049\/jimmunol.169.11.6102","article-title":"NK cell CD94\/NKG2A inhibitory receptors are internalized and recycle independently of inhibitory signaling processes","volume":"169","author":"Borrego","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0095","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/cmi.2016.26","article-title":"NK cell education via nonclassical MHC and non-MHC ligands","volume":"14","author":"He","year":"2017","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0100","doi-asserted-by":"crossref","first-page":"892","DOI":"10.4049\/jimmunol.1403046","article-title":"Increased CD226 Expression on CD8+ T Cells Is Associated with Upregulated Cytokine Production and Endothelial Cell Injury in Patients with Systemic Sclerosis","volume":"195","author":"Ayano","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0105","doi-asserted-by":"crossref","first-page":"658843","DOI":"10.3389\/fimmu.2021.658843","article-title":"Lymphocyte-Related Immunological Indicators for Stratifying Mycobacterium tuberculosis Infection","volume":"12","author":"Luo","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0110","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1186\/s12916-020-01849-7","article-title":"The impact of HIV infection on tuberculosis transmission in a country with low tuberculosis incidence: a national retrospective study using molecular epidemiology","volume":"18","author":"Winter","year":"2020","journal-title":"BMC Med."},{"key":"10.1016\/j.intimp.2023.110360_b0115","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1084\/jem.192.3.347","article-title":"Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2","volume":"192","author":"Scanga","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2023.110360_b0120","doi-asserted-by":"crossref","first-page":"109696","DOI":"10.1016\/j.celrep.2021.109696","article-title":"CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection","volume":"36","author":"Lu","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.intimp.2023.110360_b0125","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S1074-7613(00)70060-4","article-title":"DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes","volume":"4","author":"Shibuya","year":"1996","journal-title":"Immunity."},{"key":"10.1016\/j.intimp.2023.110360_b0130","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1084\/jem.20081611","article-title":"Accelerated tumor growth in mice deficient in DNAM-1 receptor","volume":"205","author":"Iguchi-Manaka","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2023.110360_b0135","doi-asserted-by":"crossref","first-page":"8109","DOI":"10.1038\/ncomms9109","article-title":"'Emergency exit' of bone-marrow-resident CD34(+)DNAM-1(bright)CXCR4(+)-committed lymphoid precursors during chronic infection and inflammation","volume":"6","author":"Bozzano","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2023.110360_b0140","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.intimp.2014.12.036","article-title":"CD226 as a genetic adjuvant to enhance immune efficacy induced by Ag85A DNA vaccination","volume":"25","author":"Li","year":"2015","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2023.110360_b0145","doi-asserted-by":"crossref","unstructured":"E.O. Long, H.S. Kim, D. Liu, M.E. Peterson, and S. Rajagopalan, Controlling natural killer cell responses: integration of signals for activation and inhibition, Annu. Rev. Immunol. 31 (2013) 227\u2013258, , L. Chen, and D.B. Flies, Molecular mechanisms of T cell co-stimulation and co-inhibition, Nat. Rev. Immunol. 13 (2013) 227\u2013242, https:\/\/doi.org\/10.1038\/nri3405.","DOI":"10.1146\/annurev-immunol-020711-075005"},{"key":"10.1016\/j.intimp.2023.110360_b0150","doi-asserted-by":"crossref","unstructured":"B. Yang, X. Wang, J. Jiang, X. Cheng, Involvement of CD244 in regulating CD4+ T cell immunity in patients with active tuberculosis, PLoS One. 8 (2013) e63261, https:\/\/doi.org\/10.1371\/journal.pone.0063261.","DOI":"10.1371\/journal.pone.0063261"},{"key":"10.1016\/j.intimp.2023.110360_b0155","doi-asserted-by":"crossref","unstructured":"B.L. Phillips, U.S. Gautam, A.N. Bucsan, T.W. Foreman, N.A. Golden, T. Niu, D. Kaushal, S. Mehra, LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model, PLoS One. 12 (2017) e0180413, https:\/\/doi.org\/10.1371\/journal.pone.0180413.","DOI":"10.1371\/journal.pone.0180413"},{"key":"10.1016\/j.intimp.2023.110360_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.tube.2022.102221","article-title":"Evaluating the diversity of circulating natural killer cells between active tuberculosis and latent tuberculosis infection","volume":"135","author":"Zhou","year":"2022","journal-title":"Tuberculosis (Edinb)."},{"key":"10.1016\/j.intimp.2023.110360_b0165","doi-asserted-by":"crossref","unstructured":"Q. Zhang, J. Bi, X. Zheng, Y. Chen, H. Wang, W. Wu, Z. Wang, Q. Wu, H. Peng, H. Wei, R. Sun, and Z. Tian, Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity, Nat. Immunol. 19 (2018) 723\u2013732, https:\/\/doi.org\/10.1038\/s41590-018-0132-0, C. Zhang, X.M. Wang, S.R. Li, T. Twelkmeyer, W.H. Wang, S.Y. Zhang, S.F. Wang, J.Z. Chen, X. Jin, Y.Z. Wu, X.W. Chen, S.D. Wang, J.Q. Niu, H.R. Chen, and H. Tang, NKG2A is a NK cell exhaustion checkpoint for HCV persistence, Nat. Commun. 10 (2019) 1507, https:\/\/doi.org\/10.1038\/s41467-019-09212-y.","DOI":"10.1038\/s41590-018-0132-0"},{"key":"10.1016\/j.intimp.2023.110360_b0170","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/0092-8674(84)90039-4","article-title":"An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein","volume":"36","author":"Meuer","year":"1984","journal-title":"Cell."},{"key":"10.1016\/j.intimp.2023.110360_b0175","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1146\/annurev.iy.09.040191.000331","article-title":"Role of lymphocyte adhesion receptors in transient interactions and cell locomotion","volume":"9","author":"Dustin","year":"1991","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0180","doi-asserted-by":"crossref","first-page":"21280","DOI":"10.1074\/jbc.M807053200","article-title":"LFA-1 and CD2 synergize for the Erk1\/2 activation in the Natural Killer (NK) cell immunological synapse","volume":"284","author":"Zheng","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2023.110360_b0185","doi-asserted-by":"crossref","unstructured":"D.F. Barber, M. Faure, and E.O. Long, LFA-1 contributes an early signal for NK cell cytotoxicity, J. Immunol. 173 (2004) 3653\u20133659, https:\/\/doi.org\/10.4049\/jimmunol.173.6.3653, T.A. Springer, Adhesion receptors of the immune system, Nature. 346 (1990) 425\u2013434, https:\/\/doi.org\/10.1038\/346425a0.","DOI":"10.4049\/jimmunol.173.6.3653"},{"key":"10.1016\/j.intimp.2023.110360_b0190","doi-asserted-by":"crossref","first-page":"36748","DOI":"10.1074\/jbc.M300702200","article-title":"CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells","volume":"278","author":"Kojima","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2023.110360_b0195","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1182\/blood-2009-01-201632","article-title":"Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors","volume":"114","author":"Bryceson","year":"2009","journal-title":"Blood."},{"key":"10.1016\/j.intimp.2023.110360_b0200","doi-asserted-by":"crossref","first-page":"943344","DOI":"10.3389\/fimmu.2022.943344","article-title":"The Immunological Synapse: An Emerging Target for Immune Evasion by Bacterial Pathogens","volume":"13","author":"Capitani","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0205","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0952-7915(00)00241-7","article-title":"NK cells and NKT cells in innate defense against viral infections","volume":"13","author":"Biron","year":"2001","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0210","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.4049\/jimmunol.170.5.2399","article-title":"Memory CD8+ T cells provide an early source of IFN-gamma","volume":"170","author":"Kambayashi","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0215","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.molimm.2004.07.034","article-title":"Activation of NK cell cytotoxicity","volume":"42","author":"Smyth","year":"2005","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.intimp.2023.110360_b0220","doi-asserted-by":"crossref","first-page":"15627","DOI":"10.1038\/ncomms15627","article-title":"Expression of CD226 is associated to but not required for NK cell education","volume":"8","author":"Wagner","year":"2017","journal-title":"Nat. Commun."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576923006835?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576923006835?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:55:45Z","timestamp":1778619345000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576923006835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":44,"alternative-id":["S1567576923006835"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110360","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Upregulation of CD226 on subsets of T cells and NK cells is associated with upregulated adhesion molecules and cytotoxic factors in patients with tuberculosis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110360","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110360"}}