{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:38:16Z","timestamp":1790249896590,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:00:00Z","timestamp":1693353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871183"],"award-info":[{"award-number":["31871183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172139"],"award-info":[{"award-number":["82172139"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372153"],"award-info":[{"award-number":["82372153"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.intimp.2023.110867","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:26:36Z","timestamp":1693527996000},"page":"110867","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"PA","title":["Keratin7 and Desmoplakin are involved in acute lung injury induced by sepsis through RAGE"],"prefix":"10.1016","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2856-6626","authenticated-orcid":false,"given":"Qi","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirui","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiju","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoliang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuiwang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihua","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenfeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingqi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaobing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2023.110867_b0005","article-title":"Sepsis: pathophysiology and clinical management","volume":"353","author":"Gotts","year":"2016","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.intimp.2023.110867_b0010","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.124061","article-title":"Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome","volume":"4","author":"Englert","year":"2019","journal-title":"JCI Insight"},{"issue":"32","key":"10.1016\/j.intimp.2023.110867_b0015","doi-asserted-by":"crossref","first-page":"12153","DOI":"10.1021\/acs.jafc.2c08926","article-title":"Sepsis-Induced Acute Lung Injury Is Alleviated by Small Molecules from Dietary Plants via Pyroptosis Modulation","volume":"71","author":"Wu","year":"2023","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0020","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12950-023-00338-x","article-title":"Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury","volume":"20","author":"Kim","year":"2023","journal-title":"J. Inflamm. (Lond.)"},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0025","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s12929-023-00957-9","article-title":"Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis","volume":"30","author":"Jiao","year":"2023","journal-title":"J. Biomed. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0030","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/s41401-021-00676-7","article-title":"Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury","volume":"43","author":"Deng","year":"2022","journal-title":"Acta Pharmacol. Sin."},{"issue":"2","key":"10.1016\/j.intimp.2023.110867_b0035","article-title":"Molecular Actors of Inflammation and Their Signaling Pathways: Mechanistic Insights from Zebrafish","volume":"12","author":"Leiba","year":"2023","journal-title":"Biology (Basel)"},{"issue":"5","key":"10.1016\/j.intimp.2023.110867_b0040","doi-asserted-by":"crossref","first-page":"785","DOI":"10.14336\/AD.2017.1028","article-title":"The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease","volume":"9","author":"Zhao","year":"2018","journal-title":"Aging Dis."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0045","doi-asserted-by":"crossref","first-page":"611","DOI":"10.14336\/AD.2018.0707","article-title":"BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1\/RAGE\/NF-\u03baB Pathway","volume":"10","author":"Han","year":"2019","journal-title":"Aging Dis."},{"issue":"8","key":"10.1016\/j.intimp.2023.110867_b0050","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.7150\/ijbs.73504","article-title":"Targeting HMGB1: An available Therapeutic Strategy for Breast Cancer Therapy","volume":"18","author":"Dong","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"9","key":"10.1016\/j.intimp.2023.110867_b0055","doi-asserted-by":"crossref","first-page":"6714","DOI":"10.1002\/jcp.26341","article-title":"HMGB1 contributes to the irradiation-induced endothelial barrier injury through receptor for advanced glycation endproducts (RAGE)","volume":"233","author":"Zhou","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.intimp.2023.110867_b0060","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1146\/annurev-med-041316-085215","article-title":"Targeting RAGE Signaling in Inflammatory Disease","volume":"69","author":"Hudson","year":"2018","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.intimp.2023.110867_b0065","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3389\/fimmu.2020.00484","article-title":"Targeting Inflammation Driven by HMGB1","volume":"11","author":"Yang","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.110867_b0070","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.760186","article-title":"Blocking HMGB1\/RAGE Signaling by Berberine Alleviates A1 Astrocyte and Attenuates Sepsis-Associated Encephalopathy","volume":"12","author":"Shi","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2023.110867_b0075","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.931473","article-title":"Pathophysiology of RAGE in inflammatory diseases","volume":"13","author":"Dong","year":"2022","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2023.110867_b0080","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/cpt.148","article-title":"Emerging Targets for Therapeutic Development in Diabetes and Its Complications: The RAGE Signaling Pathway","volume":"98","author":"Litwinoff","year":"2015","journal-title":"Clin. Pharmacol. Ther."},{"issue":"2","key":"10.1016\/j.intimp.2023.110867_b0085","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1161\/CIRCRESAHA.115.306532","article-title":"RhoA\/Rho-Kinase in the Cardiovascular System","volume":"118","author":"Shimokawa","year":"2016","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.intimp.2023.110867_b0090","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1159\/000487780","article-title":"Mdia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability","volume":"45","author":"Zhou","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0095","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1042\/BST20210112","article-title":"Progress in the therapeutic inhibition of Cdc42 signalling","volume":"49","author":"Murphy","year":"2021","journal-title":"Biochem. Soc. Trans."},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0100","doi-asserted-by":"crossref","first-page":"6840","DOI":"10.1038\/s41467-022-34529-6","article-title":"pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation","volume":"13","author":"Boix","year":"2022","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0105","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s10719-020-09956-6","article-title":"Glycation reaction and the role of the receptor for advanced glycation end-products in immunity and social behavior","volume":"38","author":"Leerach","year":"2021","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.intimp.2023.110867_b0110","doi-asserted-by":"crossref","unstructured":"M. Ji, J. Sun, J. Zhao, Verbascoside represses malignant phenotypes of esophageal squamous cell carcinoma cells by inhibiting CDC42 via the HMGB1\/RAGE axis, Hum Exp Toxicol 41 (2022) 9603271221127429.","DOI":"10.1177\/09603271221127429"},{"issue":"7","key":"10.1016\/j.intimp.2023.110867_b0115","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.7150\/ijbs.56694","article-title":"NDRG1 regulates Filopodia-induced Colorectal Cancer invasiveness via modulating CDC42 activity","volume":"17","author":"Aikemu","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.intimp.2023.110867_b0120","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ijbiomac.2022.08.002","article-title":"Biological importance and pharmaceutical significance of keratin: A review","volume":"219","author":"Sarma","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0125","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1073\/pnas.0710728105","article-title":"Micromechanical properties of keratin intermediate filament networks","volume":"105","author":"Sivaramakrishnan","year":"2008","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2023.110867_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2021.198333","article-title":"Host-cell dependent role of phosphorylated keratin 8 during influenza A\/NWS\/33 virus (H1N1) infection in mammalian cells","volume":"295","author":"De Conto","year":"2021","journal-title":"Virus Res."},{"key":"10.1016\/j.intimp.2023.110867_b0135","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.semcdb.2021.08.010","article-title":"Colorectal keratins: Integrating nutrition, metabolism and colorectal health","volume":"128","author":"Evans","year":"2022","journal-title":"Semin. Cell Dev. Biol."},{"issue":"43","key":"10.1016\/j.intimp.2023.110867_b0140","doi-asserted-by":"crossref","first-page":"33242","DOI":"10.1074\/jbc.M110.132357","article-title":"p38 MAP kinase and MAPKAP kinases MK2\/3 cooperatively phosphorylate epithelial keratins","volume":"285","author":"Menon","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"18","key":"10.1016\/j.intimp.2023.110867_b0145","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.229534","article-title":"Keratins regulate Hsp70-mediated nuclear localization of p38 mitogen-activated protein kinase","volume":"132","author":"Lee","year":"2019","journal-title":"J. Cell Sci."},{"issue":"5","key":"10.1016\/j.intimp.2023.110867_b0150","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s00018-022-04244-y","article-title":"Bidirectional regulation of desmosome hyperadhesion by keratin isotypes and desmosomal components","volume":"79","author":"B\u00fcchau","year":"2022","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0155","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/s41467-022-35741-0","article-title":"Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus","volume":"14","author":"Sigmund","year":"2023","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.intimp.2023.110867_b0160","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.jcmgh.2021.12.009","article-title":"Desmoplakin Maintains Transcellular Keratin Scaffolding and Protects From Intestinal Injury","volume":"13","author":"Gross","year":"2022","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"issue":"21","key":"10.1016\/j.intimp.2023.110867_b0165","doi-asserted-by":"crossref","first-page":"4397","DOI":"10.1007\/s00018-019-03424-7","article-title":"An intact keratin network is crucial for mechanical integrity and barrier function in keratinocyte cell sheets","volume":"77","author":"Karsch","year":"2020","journal-title":"Cell. Mol. Life Sci."},{"issue":"17","key":"10.1016\/j.intimp.2023.110867_b0170","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1016\/j.yexcr.2009.07.013","article-title":"Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes","volume":"315","author":"Liovic","year":"2009","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0175","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/SHK.0000000000001164","article-title":"Premise for Standardized Sepsis Models","volume":"51","author":"Remick","year":"2019","journal-title":"Shock"},{"issue":"Suppl 1","key":"10.1016\/j.intimp.2023.110867_b0180","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/01.shk.0000191414.94461.7e","article-title":"Cecal ligation and puncture","volume":"24","author":"Hubbard","year":"2005","journal-title":"Shock"},{"key":"10.1016\/j.intimp.2023.110867_b0185","article-title":"Proteomic analysis identifies three reliable biomarkers of intestinal inflammation in the stools of patients with Inflammatory Bowel Disease","author":"Vitali","year":"2022","journal-title":"J. Crohns Colitis"},{"issue":"8","key":"10.1016\/j.intimp.2023.110867_b0190","doi-asserted-by":"crossref","first-page":"9030","DOI":"10.1096\/fj.201800263RR","article-title":"Liver disease-associated keratin 8 and 18 mutations modulate keratin acetylation and methylation","volume":"33","author":"Jang","year":"2019","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.intimp.2023.110867_b0195","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1158\/1541-7786.MCR-21-0266","article-title":"Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1\/cdc42\/Myosin II","volume":"20","author":"Kalli","year":"2022","journal-title":"Mol. Cancer Res."},{"issue":"8","key":"10.1016\/j.intimp.2023.110867_b0200","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1091\/mbc.11.8.2513","article-title":"Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways","volume":"11","author":"Meriane","year":"2000","journal-title":"Mol. Biol. Cell"},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0205","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/stem.2924","article-title":"mDia1 and Cdc42 Regulate Activin B-Induced Migration of Bone Marrow-Derived Mesenchymal Stromal Cells","volume":"37","author":"Wang","year":"2019","journal-title":"Stem Cells"},{"issue":"6","key":"10.1016\/j.intimp.2023.110867_b0210","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22063279","article-title":"Articular Chondrocyte Phenotype Regulation through the Cytoskeleton and the Signaling Processes That Originate from or Converge on the Cytoskeleton: Towards a Novel Understanding of the Intersection between Actin Dynamics and Chondrogenic Function","volume":"22","author":"Lauer","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.intimp.2023.110867_b0215","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23052596","article-title":"Amelioration of Endotoxin-Induced Acute Lung Injury and Alveolar Epithelial Cells Apoptosis by Simvastatin Is Associated with Up-Regulation of Survivin\/NF-kB\/p65 Pathway","volume":"23","author":"Ne\u017ei\u0107","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2023.110867_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102432","article-title":"Macrophage SAMSN1 protects against sepsis-induced acute lung injury in mice","volume":"56","author":"Jiang","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2023.110867_b0225","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.12659\/MSM.912867","article-title":"High-Mobility Group Box 1 (HMGB1) and Autophagy in Acute Lung Injury (ALI): A Review","volume":"25","author":"Qu","year":"2019","journal-title":"Med. Sci. Monit."},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0230","first-page":"22","article-title":"Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect","volume":"9","author":"Luo","year":"2022","journal-title":"Mil. Med. Res."},{"key":"10.1016\/j.intimp.2023.110867_b0235","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.smim.2018.02.011","article-title":"High-mobility group box 1 protein (HMGB1) operates as an alarmin outside as well as inside cells","volume":"38","author":"Andersson","year":"2018","journal-title":"Semin. Immunol."},{"issue":"7","key":"10.1016\/j.intimp.2023.110867_b0240","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14071623","article-title":"High Keratin-7 Expression in Benign Peri-Tumoral Prostatic Glands Is Predictive of Bone Metastasis Onset and Prostate Cancer-Specific Mortality","volume":"14","author":"Dariane","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"1","key":"10.1016\/j.intimp.2023.110867_b0245","doi-asserted-by":"crossref","first-page":"11979","DOI":"10.1038\/s41598-023-39066-w","article-title":"Keratin 7 expression in different anatomical parts of colonic epithelium in inflammatory bowel diseases and its prognostic value: a 3-year follow-up study","volume":"13","author":"Tenhami","year":"2023","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.intimp.2023.110867_b0250","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a018275","article-title":"Types I and II Keratin Intermediate Filaments","volume":"10","author":"Jacob","year":"2018","journal-title":"Cold Spring Harb. Perspect. Biol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692301192X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692301192X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T18:05:22Z","timestamp":1761588322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156757692301192X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":50,"alternative-id":["S156757692301192X"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110867","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Keratin7 and Desmoplakin are involved in acute lung injury induced by sepsis through RAGE","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2023.110867","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110867"}}