{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:25:06Z","timestamp":1792171506140,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972945"],"award-info":[{"award-number":["81972945"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014354","name":"Milstein Medical Asian American Partnership Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014354","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.intimp.2023.111082","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T20:49:07Z","timestamp":1698785347000},"page":"111082","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"PA","title":["Risk factors predisposing relapse of bullous pemphigoid at initial diagnosis: A retrospective cohort study of 205 patients"],"prefix":"10.1016","volume":"125","author":[{"given":"Yangchun","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiman","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengnan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongzhong","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8280-7291","authenticated-orcid":false,"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2023.111082_b0005","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.jaci.2020.02.013","article-title":"Autoimmune bullous skin diseases, pemphigus and pemphigoid","volume":"145","author":"Egami","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.intimp.2023.111082_b0010","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3389\/fmed.2018.00139","article-title":"High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid","volume":"5","author":"Koga","year":"2018","journal-title":"Front Med (lausanne)"},{"key":"10.1016\/j.intimp.2023.111082_b0015","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1001\/archdermatol.2009.53","article-title":"Risk factors for relapse in patients with bullous pemphigoid in clinical remission: a multicenter, prospective, cohort study","volume":"145","author":"Bernard","year":"2009","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.intimp.2023.111082_b0020","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1080\/09546634.2020.1782325","article-title":"Emerging treatments for bullous pemphigoid","volume":"33","author":"Garrido","year":"2022","journal-title":"J. Dermatolog. Treat."},{"key":"10.1016\/j.intimp.2023.111082_b0025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.912876","article-title":"Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms","volume":"13","author":"Cole","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2023.111082_b0030","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1080\/07853890.2018.1443346","article-title":"Relapse of bullous pemphigoid: an update on this stubborn clinical problem","volume":"50","author":"Wang","year":"2018","journal-title":"Ann. Med."},{"key":"10.1016\/j.intimp.2023.111082_b0035","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1001\/jamadermatol.2013.5757","article-title":"Clinical and immunologic factors associated with bullous pemphigoid relapse during the first year of treatment: a multicenter, prospective study","volume":"150","author":"Fichel","year":"2014","journal-title":"JAMA Dermatol."},{"key":"10.1016\/j.intimp.2023.111082_b0040","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1111\/jdv.18220","article-title":"Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV)","volume":"36","author":"Borradori","year":"2022","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"1","key":"10.1016\/j.intimp.2023.111082_b0045","doi-asserted-by":"crossref","first-page":"10519","DOI":"10.1038\/s41598-022-14950-z","article-title":"Bullous pemphigoid diagnosis: the role of routine formalin-fixed paraffin-embedded skin tissue immunochemistry","volume":"12","author":"Oh","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2023.111082_b0050","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.jaad.2011.06.032","article-title":"Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts","volume":"66","author":"Murrell","year":"2012","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.intimp.2023.111082_b0055","first-page":"511","article-title":"Lack of association between bullous pemphigoid and autoimmune thyroid disease: A population-based case-control study","volume":"20","author":"Wu","year":"2022","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"10.1016\/j.intimp.2023.111082_b0060","doi-asserted-by":"crossref","first-page":"4833","DOI":"10.1038\/s41598-017-04687-5","article-title":"Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome","volume":"7","author":"Giusti","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2023.111082_b0065","doi-asserted-by":"crossref","first-page":"18001","DOI":"10.1038\/srep18001","article-title":"Integrating longitudinal serum IL-17 and IL-23 follow-up, along with autoantibodies variation, contributes to predict bullous pemphigoid outcome","volume":"5","author":"Plee","year":"2015","journal-title":"Sci. Rep."},{"issue":"863\u2013872","key":"10.1016\/j.intimp.2023.111082_b0070","doi-asserted-by":"crossref","first-page":"e863","DOI":"10.1016\/j.jaci.2016.08.012","article-title":"Bullous pemphigoid outcome is associated with CXCL10-induced matrix metalloproteinase 9 secretion from monocytes and neutrophils but not lymphocytes","volume":"139","author":"Riani","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.intimp.2023.111082_b0075","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000381143","article-title":"Positive Direct Immunofluorescence Is of Better Value than ELISA-BP180 and ELISA-BP230 Values for the Prediction of Relapse after Treatment Cessation in Bullous Pemphigoid: A Retrospective Study of 97 Patients","volume":"231","author":"Ingen-Housz-Oro","year":"2015","journal-title":"Dermatology"},{"key":"10.1016\/j.intimp.2023.111082_b0080","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jaad.2020.05.161","article-title":"Subepithelial autoimmune bullous dermatoses disease activity assessment and therapy","volume":"85","author":"Montagnon","year":"2021","journal-title":"J. Am. Acad. Dermatol."},{"issue":"12","key":"10.1016\/j.intimp.2023.111082_b0085","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9123928","article-title":"Presence of Cutaneous Complement Deposition Distinguishes between Immunological and Histological Features of Bullous Pemphigoid-Insights from a Retrospective Cohort Study","volume":"9","author":"Stander","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.intimp.2023.111082_b0090","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/bjd.14822","article-title":"Complement in bullous pemphigoid: results from a large observational study","volume":"176","author":"Romeijn","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.intimp.2023.111082_b0095","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/rheumatology\/kev322","article-title":"Serum prealbumin is an independent predictor of mortality in systemic sclerosis outpatients","volume":"55","author":"Codullo","year":"2016","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.intimp.2023.111082_b0100","first-page":"3775","article-title":"Serum albumin and prealbumin do not predict recurrence in patients with breast cancer","volume":"34","author":"Fujii","year":"2014","journal-title":"Anticancer Res"},{"key":"10.1016\/j.intimp.2023.111082_b0105","first-page":"8","article-title":"Nutritional Laboratory Markers in Malnutrition","author":"Keller","year":"2019","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.intimp.2023.111082_b0110","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jjcc.2021.05.009","article-title":"The C-reactive protein to prealbumin ratio on admission and its relationship with outcome in patients hospitalized for acute heart failure","volume":"78","author":"Yamada","year":"2021","journal-title":"J. Cardiol."},{"key":"10.1016\/j.intimp.2023.111082_b0115","doi-asserted-by":"crossref","first-page":"393","DOI":"10.4103\/lungindia.lungindia_494_18","article-title":"Serum inflammatory markers and nutritional status in patients with stable chronic obstructive pulmonary disease","volume":"36","author":"Arora","year":"2019","journal-title":"Lung India"},{"key":"10.1016\/j.intimp.2023.111082_b0120","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1017\/S0029665110001977","article-title":"Encouraging appropriate, evidence-based use of oral nutritional supplements","volume":"69","author":"Stratton","year":"2010","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.intimp.2023.111082_b0125","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/jdv.13839","article-title":"Prognostic clinical factors associated with remission and relapse in bullous pemphigoid","volume":"31","author":"Lee","year":"2017","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.intimp.2023.111082_b0130","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1080\/00015550510034146","article-title":"Bullous pemphigoid and Graves' disease: an association between skin and thyroid autoimmunity","volume":"85","author":"Fiorucci","year":"2005","journal-title":"Acta Derm. Venereol."},{"key":"10.1016\/j.intimp.2023.111082_b0135","doi-asserted-by":"crossref","first-page":"20","DOI":"10.5070\/D35Q17B9W1","article-title":"Coexistence of bullous pemphigoid, vitiligo, and thyroid disease: a multiple autoimmune syndrome?","volume":"11","author":"Tirado-Sanchez","year":"2005","journal-title":"Dermatol. Online J."},{"key":"10.1016\/j.intimp.2023.111082_b0140","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0190-9622(81)70116-6","article-title":"Bullous pemphigoid and Hashimoto's thyroiditis","volume":"5","author":"Callen","year":"1981","journal-title":"J. Am. Acad. Dermatol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692301408X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692301408X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T18:03:16Z","timestamp":1761588196000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156757692301408X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":28,"alternative-id":["S156757692301408X"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2023.111082","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors predisposing relapse of bullous pemphigoid at initial diagnosis: A retrospective cohort study of 205 patients","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2023.111082","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111082"}}