{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:58:46Z","timestamp":1784901526300,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.intimp.2024.111928","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T23:07:10Z","timestamp":1711494430000},"page":"111928","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Protective effect of astaxanthin on ANCA-associated vasculitis"],"prefix":"10.1016","volume":"132","author":[{"given":"Ruo-lan","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-chun","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Run-hong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-qun","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.intimp.2024.111928_b0005","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/s41584-022-00819-y","article-title":"Genetics of ANCA-associated vasculitis: role in pathogenesis, classification and management","volume":"18","author":"Trivioli","year":"2022","journal-title":"Nat. Rev. Rheumatol."},{"issue":"20","key":"10.1016\/j.intimp.2024.111928_b0010","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1182\/blood-2018-11-844530","article-title":"Neutrophils and NETs in modulating acute and chronic inflammation","volume":"133","author":"Castanheira","year":"2019","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.intimp.2024.111928_b0015","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.tim.2022.10.002","article-title":"Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease","volume":"31","author":"Poli","year":"2023","journal-title":"Trends Microbiol."},{"issue":"1","key":"10.1016\/j.intimp.2024.111928_b0020","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41572-020-0204-y","article-title":"ANCA-associated vasculitis","volume":"6","author":"Kitching","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"2","key":"10.1016\/j.intimp.2024.111928_b0025","article-title":"Pathogenesis and therapeutic interventions for ANCA-associated vasculitis","volume":"15","author":"Nakazawa","year":"2019","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.intimp.2024.111928_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112179","article-title":"Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases","volume":"145","author":"Kohandel","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"8","key":"10.1016\/j.intimp.2024.111928_b0035","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00394-010-0103-1","article-title":"Astaxanthin addition improves human neutrophils function: in vitro study","volume":"49","author":"Macedo","year":"2010","journal-title":"Eur. J. Nutr."},{"issue":"7","key":"10.1016\/j.intimp.2024.111928_b0040","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.tiv.2012.06.010","article-title":"Carbonyl stress and a combination of astaxanthin\/vitamin C induce biochemical changes in human neutrophils","volume":"26","author":"Guerra","year":"2012","journal-title":"Toxicol. In Vitro"},{"issue":"1","key":"10.1016\/j.intimp.2024.111928_b0045","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.cbi.2012.03.005","article-title":"Combined astaxanthin and fish oil supplementation improves glutathione-based redox balance in rat plasma and neutrophils","volume":"197","author":"Barros","year":"2012","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.intimp.2024.111928_b0050","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jconrel.2021.08.047","article-title":"Simultaneous inhibition of breast cancer and its liver and lung metastasis by blocking inflammatory feed-forward loops","volume":"338","author":"Lu","year":"2021","journal-title":"J. Control. Release"},{"issue":"4","key":"10.1016\/j.intimp.2024.111928_b0055","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.2353\/ajpath.2009.080458","article-title":"Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis","volume":"174","author":"Little","year":"2009","journal-title":"Am. J. Pathol."},{"issue":"12","key":"10.1016\/j.intimp.2024.111928_b0060","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1042\/CS20200497","article-title":"Sphingosine-1-phosphate receptor modulator FTY720 attenuates experimental myeloperoxidase-ANCA vasculitis in a T cell-dependent manner","volume":"134","author":"Wang","year":"2020","journal-title":"Clin. Sci. (Lond., Engl.: 1979)"},{"key":"10.1016\/j.intimp.2024.111928_b0065","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/4629189","article-title":"Astaxanthin attenuates hypertensive vascular remodeling by protecting vascular smooth muscle cells from oxidative stress-induced mitochondrial dysfunction","volume":"2020","author":"Chen","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"6","key":"10.1016\/j.intimp.2024.111928_b0070","doi-asserted-by":"crossref","DOI":"10.3390\/md19060346","article-title":"Astaxanthin protects dendritic cells from lipopolysaccharide-induced immune dysfunction","volume":"19","author":"Yin","year":"2021","journal-title":"Mar. Drugs"},{"issue":"4","key":"10.1016\/j.intimp.2024.111928_b0075","doi-asserted-by":"crossref","DOI":"10.3390\/cells9040915","article-title":"Neutrophil extracellular traps (NETs) take the central stage in driving autoimmune responses","volume":"9","author":"Fousert","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.intimp.2024.111928_b0080","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1146\/annurev-cellbio-020520-111016","article-title":"Cellular mechanisms of NETosis","volume":"36","author":"Thiam","year":"2020","journal-title":"Annu. Rev. Cell Dev. Biol."},{"issue":"9","key":"10.1016\/j.intimp.2024.111928_b0085","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/1348-0421.12080","volume":"57","author":"Nagao","year":"2013","journal-title":"Microbiol. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.111928_b0090","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1136\/annrheumdis-2012-201981","article-title":"Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis","volume":"72","author":"Monach","year":"2013","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.intimp.2024.111928_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2019.07.001","article-title":"The association of serum interleukin-6 levels with clinical outcomes in antineutrophil cytoplasmic antibody-associated vasculitis","volume":"105","author":"Berti","year":"2019","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.intimp.2024.111928_b0100","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41420-021-00491-3","article-title":"ROS induces NETosis by oxidizing DNA and initiating DNA repair","volume":"7","author":"Azzouz","year":"2021","journal-title":"Cell Death Discovery"},{"issue":"1","key":"10.1016\/j.intimp.2024.111928_b0105","doi-asserted-by":"crossref","DOI":"10.1007\/s10522-020-09904-9","article-title":"Astaxanthin protects oxidative stress mediated DNA damage and enhances longevity in Saccharomyces cerevisiae","volume":"22","author":"Sudharshan","year":"2021","journal-title":"Biogerontology"},{"issue":"12","key":"10.1016\/j.intimp.2024.111928_b0110","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1002\/art.41047","article-title":"Intrinsically distinct role of neutrophil extracellular trap formation in antineutrophil cytoplasmic antibody-associated vasculitis compared to systemic lupus erythematosus","volume":"71","author":"van Dam","year":"2019","journal-title":"Arthritis Rheumatol."},{"issue":"6","key":"10.1016\/j.intimp.2024.111928_b0115","doi-asserted-by":"crossref","first-page":"F1769","DOI":"10.1152\/ajprenal.00111.2018","article-title":"Impact of MPO-ANCA-mediated oxidative imbalance on renal vasculitis","volume":"315","author":"Hilhorst","year":"2018","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.intimp.2024.111928_b0120","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cca.2019.02.022","article-title":"Myeloperoxidase - a bridge linking inflammation and oxidative stress with cardiovascular disease","volume":"493","author":"Ndrepepa","year":"2019","journal-title":"Clin. Chim. Acta"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924004466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924004466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T04:00:53Z","timestamp":1719979253000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924004466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":24,"alternative-id":["S1567576924004466"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.111928","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective effect of astaxanthin on ANCA-associated vasculitis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.111928","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111928"}}