{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:35:35Z","timestamp":1789569335091,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82127807"],"award-info":[{"award-number":["82127807"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003142"],"award-info":[{"award-number":["82003142"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015377","name":"Shanghai Key Laboratory of Molecular Imaging","doi-asserted-by":"publisher","award":["18DZ2260400"],"award-info":[{"award-number":["18DZ2260400"]}],"id":[{"id":"10.13039\/501100015377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFA0909000"],"award-info":[{"award-number":["2020YFA0909000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.intimp.2024.111939","type":"journal-article","created":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T06:43:31Z","timestamp":1712817811000},"page":"111939","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis"],"prefix":"10.1016","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3574-2410","authenticated-orcid":false,"given":"Mingming","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-4194","authenticated-orcid":false,"given":"Liying","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2024.111939_b0005","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.fitote.2019.03.013","article-title":"Triterpenoid corosolic acid attenuates HIF-1 stabilization upon cobalt (II) chloride-induced hypoxia in A549 human lung epithelial cancer cells","volume":"134","author":"Bahadori","year":"2019","journal-title":"Fitoterapia"},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0010","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12951-022-01755-5","article-title":"Tea leaf-derived exosome-like nanotherapeutics retard breast tumor growth by pro-apoptosis and microbiota modulation","volume":"21","author":"Chen","year":"2023","journal-title":"J Nanobiotechnol."},{"issue":"2","key":"10.1016\/j.intimp.2024.111939_b0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3322\/caac.21338","article-title":"Cancer statistics in China, 2015","volume":"66","author":"Chen","year":"2016","journal-title":"CA Can. J. Clin."},{"key":"10.1016\/j.intimp.2024.111939_b0020","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.fct.2017.05.021","article-title":"CRA(Crosolic acid) isolated from Actinidia valvata Dunn. Radix induces apoptosis of human gastric cancer cell line BGC823 in vitro via down-regulation of the NF-\u03baB pathway","volume":"105","author":"Cheng","year":"2017","journal-title":"Food Chem. Toxicol."},{"issue":"4","key":"10.1016\/j.intimp.2024.111939_b0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000267","article-title":"Preoperative\/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages","volume":"7","author":"Gillen","year":"2010","journal-title":"PLoS Med"},{"key":"10.1016\/j.intimp.2024.111939_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153806","article-title":"Cell suspension culture extract of Eriobotrya japonica attenuates growth and induces apoptosis in prostate cancer cells via targeting SREBP-1\/FASN-driven metabolism and AR","volume":"93","author":"Hsieh","year":"2021","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.intimp.2024.111939_b0035","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s12253-018-0420-x","article-title":"Pancreatic cancer stem cells: features and detection methods","volume":"24","author":"Ishiwata","year":"2018","journal-title":"Pathol. Oncol. Res."},{"key":"10.1016\/j.intimp.2024.111939_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112313","article-title":"Corosolic acid reduces A549 and PC9 cell proliferation, invasion, and chemoresistance in NSCLC via inducing mitochondrial and liposomal oxidative stress","volume":"144","author":"Jin","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0045","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ajps.2021.05.006","article-title":"Plant-derived exosome-like nanoparticles and their therapeutic activities","volume":"17","author":"Kim","year":"2022","journal-title":"Asian J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0050","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1186\/s12951-023-02006-x","article-title":"Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood-brain-barrier penetration and tumor microenvironment modulation","volume":"21","author":"Kim","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.intimp.2024.111939_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112082","article-title":"Eriobotrya japonica leaf extract attenuates airway inflammation in ovalbumin-induced mice model of asthma","volume":"253","author":"Kim","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"6","key":"10.1016\/j.intimp.2024.111939_b0060","first-page":"5747","article-title":"Corosolic acid impairs human lung adenocarcinoma A549 cells proliferation by inhibiting cell migration","volume":"17","author":"Li","year":"2019","journal-title":"Oncol. Lett."},{"issue":"22","key":"10.1016\/j.intimp.2024.111939_b0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21228444","article-title":"Pygenic acid a (PA) sensitizes metastatic breast cancer cells to anoikis and inhibits metastasis in vivo","volume":"21","author":"Lim","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0070","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13046-018-0889-x","article-title":"Corosolic acid, a natural triterpenoid, induces ER stress-dependent apoptosis in human castration resistant prostate cancer cells via activation of IRE-1\/JNK, PERK\/CHOP and TRIB3","volume":"37","author":"Ma","year":"2018","journal-title":"J. Exp. Clin. Can. Res."},{"issue":"7","key":"10.1016\/j.intimp.2024.111939_b0075","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1002\/mnfr.201300729","article-title":"Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles","volume":"58","author":"Mu","year":"2014","journal-title":"Mol. Nutr. Food Res."},{"issue":"3","key":"10.1016\/j.intimp.2024.111939_b0080","first-page":"2880","article-title":"Corosolic acid reduces 5-FU chemoresistance in human gastric cancer cells by activating AMPK","volume":"18","author":"Park","year":"2018","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0085","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12943-020-01169-7","article-title":"Metabolism of pancreatic cancer: paving the way to better anticancer strategies","volume":"19","author":"Qin","year":"2020","journal-title":"Mol. Can,"},{"key":"10.1016\/j.intimp.2024.111939_b0090","doi-asserted-by":"crossref","first-page":"9954370","DOI":"10.1155\/2021\/9954370","article-title":"Identification of the ferroptosis-associated gene signature to predict the prognostic status of endometrial Carcinoma patients","volume":"2021","author":"Qin","year":"2021","journal-title":"Comput. Math. Methods Med."},{"issue":"5","key":"10.1016\/j.intimp.2024.111939_b0095","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.cell.2017.07.007","article-title":"Enhancer reprogramming promotes pancreatic cancer metastasis","volume":"170","author":"Roe","year":"2017","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0100","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1080\/01635581.2019.1616780","article-title":"Ethanolic Extract of Lagerstroemia speciosa (L.) pers., induces apoptosis and cell cycle arrest in HepG2 cells","volume":"72","author":"Rohit Singh","year":"2020","journal-title":"Nutr. Cancer"},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0105","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12876-020-1159-x","article-title":"Needle tract seeding recurrence of pancreatic cancer in the gastric wall with paragastric lymph node metastasis after endoscopic ultrasound-guided fine needle aspiration followed by pancreatectomy: a case report and literature review","volume":"20","author":"Sato","year":"2020","journal-title":"BMC Gastroenterol."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0110","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21551","article-title":"Cancer statistics, 2019","volume":"69","author":"Siegel","year":"2019","journal-title":"CA Can. J. Clin."},{"issue":"11","key":"10.1016\/j.intimp.2024.111939_b0115","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/pin.13158","article-title":"ASMTL-AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis","volume":"71","author":"Sui","year":"2021","journal-title":"Pathol. Int."},{"issue":"12","key":"10.1016\/j.intimp.2024.111939_b0120","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1158\/0008-5472.CAN-14-3095","article-title":"Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites","volume":"75","author":"Wang","year":"2015","journal-title":"Can. Res."},{"issue":"5","key":"10.1016\/j.intimp.2024.111939_b0125","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19051309","article-title":"Corosolic acid induces non-apoptotic cell death through generation of lipid reactive oxygen species production in human renal carcinoma caki cells","volume":"19","author":"Woo","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.intimp.2024.111939_b0130","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1111\/bph.15372","article-title":"Corosolic acid inhibits colorectal cancer cells growth as a novel HER2\/HER3 heterodimerization inhibitor","volume":"178","author":"Zhang","year":"2021","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.111939_b0135","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12943-020-01167-9","article-title":"PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications","volume":"19","author":"Zhu","year":"2020","journal-title":"Mol. Can."},{"key":"10.1016\/j.intimp.2024.111939_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115566","article-title":"Traditional uses, phytochemistry, pharmacology, and toxicity of Eriobotrya japonica leaves: a summary","volume":"298","author":"Zhu","year":"2022","journal-title":"J. Ethnopharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924004570?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924004570?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T04:01:47Z","timestamp":1719979307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924004570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":28,"alternative-id":["S1567576924004570"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.111939","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.111939","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111939"}}