{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:35:43Z","timestamp":1777494943368,"version":"3.51.4"},"reference-count":173,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.intimp.2024.112077","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T06:18:04Z","timestamp":1712989084000},"page":"112077","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Roles of IRF4 in various immune cells in systemic lupus erythematosus"],"prefix":"10.1016","volume":"133","author":[{"given":"Ze Xiu","family":"Xiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongzhen","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song Guo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0005","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.autrev.2011.08.006","article-title":"Interferon regulatory factors: beyond the antiviral response and their link to the development of autoimmune pathology","volume":"11","author":"Santana-de Anda","year":"2011","journal-title":"Autoimmun. Rev."},{"issue":"6\u20137","key":"10.1016\/j.intimp.2024.112077_b0010","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.biochi.2007.01.014","article-title":"The IRF family, revisited","volume":"89","author":"Paun","year":"2007","journal-title":"Biochimie"},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0015","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nri1552","article-title":"Roles of interferon-regulatory factors in T-helper-cell differentiation","volume":"5","author":"Lohoff","year":"2005","journal-title":"Nat. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0020","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1007\/s12272-016-0854-1","article-title":"Essential role of interferon regulatory factor 4 (IRF4) in immune cell development","volume":"39","author":"Nam","year":"2016","journal-title":"Arch. Pharm. Res."},{"issue":"35","key":"10.1016\/j.intimp.2024.112077_b0025","doi-asserted-by":"crossref","first-page":"25589","DOI":"10.1016\/S0021-9258(19)74081-2","article-title":"Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes","volume":"267","author":"Weisz","year":"1992","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0030","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1146\/annurev.immunol.19.1.623","article-title":"IRF family of transcription factors as regulators of host defense","volume":"19","author":"Taniguchi","year":"2001","journal-title":"Annu. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0035","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0092-8674(88)91307-4","article-title":"Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-\u03b2 gene regulatory elements","volume":"54","author":"Miyamoto","year":"1988","journal-title":"Cell"},{"issue":"22","key":"10.1016\/j.intimp.2024.112077_b0040","doi-asserted-by":"crossref","first-page":"10083","DOI":"10.1128\/MCB.24.22.10083-10098.2004","article-title":"Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53","volume":"24","author":"Dornan","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.intimp.2024.112077_b0045","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijbiomac.2014.01.005","article-title":"Interferon regulatory factor-1 (IRF-1) interacts with regulated in development and DNA damage response 2 (REDD2) in the cytoplasm of mouse bone marrow cells","volume":"65","author":"Gupta","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0050","doi-asserted-by":"crossref","first-page":"e1562","DOI":"10.1038\/cddis.2014.498","article-title":"Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response","volume":"5","author":"Eckhardt","year":"2014","journal-title":"Cell Death Dis."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0055","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1158\/2326-6066.CIR-18-0711","article-title":"IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell","volume":"7","author":"Shao","year":"2019","journal-title":"Cancer Immunol. Res."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0060","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1158\/0008-5472.797.65.3","article-title":"N-ras-induced growth suppression of myeloid cells is mediated by IRF-1","volume":"65","author":"Passioura","year":"2005","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0065","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0092-8674(89)90107-4","article-title":"Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes","volume":"58","author":"Harada","year":"1989","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0070","first-page":"1500","article-title":"Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system","volume":"14","author":"Harada","year":"1994","journal-title":"Mol. Cell Biol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0075","first-page":"4531","article-title":"Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system","volume":"13","author":"Tanaka","year":"1993","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0080","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1074\/jbc.273.1.194","article-title":"Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2","volume":"273","author":"Vaughan","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/A:1006888731301","article-title":"The integrated activities of IRF-2 (HiNF-M), CDP\/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes","volume":"25","author":"Aziz","year":"1998","journal-title":"Mol. Biol. Rep."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0090","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1128\/MCB.19.2.959","article-title":"Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription","volume":"19","author":"Lin","year":"1999","journal-title":"Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0095","first-page":"73","article-title":"Control of IRF-3 activation by phosphorylation","volume":"22","author":"Yoneyama","year":"2002","journal-title":"J. InterferonCcytokine Res.: Off. J. Int. Soc. Interferon Cytokine Res."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0100","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1128\/JVI.78.4.1706-1717.2004","article-title":"Innate cellular response to virus particle entry requires IRF3 but not virus replication","volume":"78","author":"Collins","year":"2004","journal-title":"J. Virol."},{"issue":"21","key":"10.1016\/j.intimp.2024.112077_b0105","doi-asserted-by":"crossref","first-page":"15325","DOI":"10.1074\/jbc.R700002200","article-title":"Triggering the innate antiviral response through IRF-3 activation","volume":"282","author":"Hiscott","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0110","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1158\/1078-0432.CCR-08-1845","article-title":"IRF4: immunity. malignancy! therapy?","volume":"15","author":"Shaffer","year":"2009","journal-title":"Clin. Cancer Res."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0115","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1006\/geno.1996.0547","article-title":"Cloning of Human Lymphocyte-Specific Interferon Regulatory Factor (hLSIRF\/hIRF4) and Mapping of the Gene to 6p23\u2013p25","volume":"37","author":"Grossman","year":"1996","journal-title":"Genomics"},{"issue":"13","key":"10.1016\/j.intimp.2024.112077_b0120","doi-asserted-by":"crossref","first-page":"6251","DOI":"10.1128\/JVI.00163-08","article-title":"Interferon Regulatory Factor 4 Is Involved in Epstein-Barr Virus-Mediated Transformation of Human B Lymphocytes","volume":"82","author":"Xu","year":"2008","journal-title":"J. Virol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0125","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1084\/jem.190.12.1837","article-title":"Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4","volume":"190","author":"Gupta","year":"1999","journal-title":"J. Exp. Med."},{"issue":"44","key":"10.1016\/j.intimp.2024.112077_b0130","doi-asserted-by":"crossref","first-page":"16001","DOI":"10.1073\/pnas.0504226102","article-title":"Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS","volume":"102","author":"Honma","year":"2005","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"41","key":"10.1016\/j.intimp.2024.112077_b0135","doi-asserted-by":"crossref","first-page":"15890","DOI":"10.1073\/pnas.0803171105","article-title":"Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector\/memory CD4+ T cells","volume":"105","author":"Honma","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0140","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cyto.2003.07.001","article-title":"IFN-\u03b1 and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells","volume":"24","author":"Lehtonen","year":"2003","journal-title":"Cytokine"},{"issue":"51","key":"10.1016\/j.intimp.2024.112077_b0145","doi-asserted-by":"crossref","first-page":"49238","DOI":"10.1074\/jbc.M205895200","article-title":"Modulation of T cell cytokine production by interferon regulatory factor-4","volume":"277","author":"Hu","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"17","key":"10.1016\/j.intimp.2024.112077_b0150","doi-asserted-by":"crossref","first-page":"17005","DOI":"10.1074\/jbc.M412584200","article-title":"The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling","volume":"280","author":"Schoenemeyer","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0155","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.bbrc.2007.01.090","article-title":"Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation","volume":"354","author":"Ouyang","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0160","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/ni.1990","article-title":"IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses","volume":"12","author":"Krausgruber","year":"2011","journal-title":"Nat. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0165","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/ajmg.a.30887","article-title":"Variation in IRF6 contributes to nonsyndromic cleft lip and palate","volume":"137","author":"Blanton","year":"2005","journal-title":"Am. J. Med. Genet. A"},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0170","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1001\/jamadermatol.2016.1336","article-title":"Hypermethylation-induced inactivation of the IRF6 gene as a possible early event in progression of vulvar squamous cell carcinoma associated with lichen sclerosus","volume":"152","author":"Rotondo","year":"2016","journal-title":"JAMA Dermatol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0175","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/viro.2000.0782","article-title":"Analysis of functional domains of interferon regulatory factor 7 and its association with IRF-3","volume":"280","author":"Au","year":"2001","journal-title":"Virology"},{"issue":"22","key":"10.1016\/j.intimp.2024.112077_b0180","doi-asserted-by":"crossref","first-page":"6660","DOI":"10.1093\/emboj\/17.22.6660","article-title":"Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7","volume":"17","author":"Marie","year":"1998","journal-title":"EMBO J."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0185","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1038\/nm.2830","article-title":"Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape","volume":"18","author":"Bidwell","year":"2012","journal-title":"Nat. Med."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0190","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.4049\/jimmunol.1101034","article-title":"Cutting edge: IRF8 Regulates Bax transcription in vivo in primary myeloid cells","volume":"187","author":"Yang","year":"2011","journal-title":"J. Immunol."},{"issue":"22","key":"10.1016\/j.intimp.2024.112077_b0195","doi-asserted-by":"crossref","first-page":"13063","DOI":"10.1074\/jbc.270.22.13063","article-title":"Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors","volume":"270","author":"Sharf","year":"1995","journal-title":"J. Biol. Chem."},{"issue":"21","key":"10.1016\/j.intimp.2024.112077_b0200","doi-asserted-by":"crossref","first-page":"8555","DOI":"10.1073\/pnas.87.21.8555","article-title":"ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains","volume":"87","author":"Fu","year":"1990","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2024.112077_b0205","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.3389\/fimmu.2018.01831","article-title":"Interferon Regulatory Factor 9 Structure and Regulation","volume":"9","author":"Paul","year":"2018","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102743","article-title":"An updated advance of autoantibodies in autoimmune diseases","volume":"20","author":"Xiao","year":"2021","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.intimp.2024.112077_b0215","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0140-6736(07)60279-7","article-title":"Systemic lupus erythematosus","volume":"369","author":"D'Cruz","year":"2007","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0220","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.rdc.2016.12.009","article-title":"Systemic lupus erythematosus and pregnancy","volume":"43","author":"Lateef","year":"2017","journal-title":"Rheum. Dis. Clin. North Am."},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0225","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24076578","article-title":"Advances in the pathogenesis and treatment of systemic lupus erythematosus","volume":"24","author":"Accapezzato","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.112077_b0230","unstructured":"A.A. Justiz Vaillant, A. Goyal, M. Varacallo, Systemic Lupus Erythematosus, StatPearls, StatPearls Publishing Copyright \u00a9 2024, StatPearls Publishing LLC., Treasure Island (FL) with ineligible companies. Disclosure: Amandeep Goyal declares no relevant financial relationships with ineligible companies. Disclosure: Matthew Varacallo declares no relevant financial relationships with ineligible companies, 2024."},{"key":"10.1016\/j.intimp.2024.112077_b0235","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3389\/fimmu.2016.00604","article-title":"Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms","volume":"7","author":"Luo","year":"2016","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0240","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1191\/096120300674499064","article-title":"Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies","volume":"9","author":"Bengtsson","year":"2000","journal-title":"Lupus"},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0245","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1136\/annrheumdis-2021-221425","article-title":"Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III trials","volume":"81","author":"Vital","year":"2022","journal-title":"Ann. Rheum. Dis."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0250","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.trsl.2011.01.006","article-title":"Interferon regulatory factors in human lupus pathogenesis","volume":"157","author":"Salloum","year":"2011","journal-title":"Transl. Res."},{"key":"10.1016\/j.intimp.2024.112077_b0255","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.immunol.26.021607.090400","article-title":"The IRF family transcription factors in immunity and oncogenesis","volume":"26","author":"Tamura","year":"2008","journal-title":"Annu. Rev. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0260","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1002\/art.39730","article-title":"Brief report: IRF4 newly identified as a common susceptibility locus for systemic sclerosis and rheumatoid arthritis in a cross-disease meta-analysis of genome-wide association studies","volume":"68","author":"Lopez-Isac","year":"2016","journal-title":"Arthritis Rheumatol. (Hoboken N.J.)"},{"key":"10.1016\/j.intimp.2024.112077_b0265","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.3389\/fimmu.2018.03085","article-title":"IRF4 and IRGs delineate clinically relevant gene expression signatures in systemic lupus erythematosus and rheumatoid arthritis","volume":"9","author":"Rodr\u00edguez-Carrio","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0270","doi-asserted-by":"crossref","unstructured":"P. Raj, E. Rai, R. Song, S. Khan, B.E. Wakeland, K. Viswanathan, C. Arana, C. Liang, B. Zhang, I. Dozmorov, F. Carr-Johnson, M. Mitrovic, G.B. Wiley, J.A. Kelly, B.R. Lauwerys, N.J. Olsen, C. Cotsapas, C.K. Garcia, C.A. Wise, J.B. Harley, S.K. Nath, J.A. James, C.O. Jacob, B.P. Tsao, C. Pasare, D.R. Karp, Q.Z. Li, P.M. Gaffney, E.K. Wakeland, Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity, eLife 5 (2016).","DOI":"10.7554\/eLife.12089"},{"key":"10.1016\/j.intimp.2024.112077_b0275","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev-immunol-020711-074950","article-title":"The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting","volume":"31","author":"Merad","year":"2013","journal-title":"Annu. Rev. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0280","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1084\/jem.194.8.1171","article-title":"CD11c+ B220+ Gr-1+ cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells","volume":"194","author":"Nakano","year":"2001","journal-title":"J. Exp. Med."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0285","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nri746","article-title":"Mouse and human dendritic cell subtypes","volume":"2","author":"Shortman","year":"2002","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0290","doi-asserted-by":"crossref","first-page":"741","DOI":"10.4049\/jimmunol.167.2.741","article-title":"The dendritic cell populations of mouse lymph nodes","volume":"167","author":"Henri","year":"2001","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0295","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.4049\/jimmunol.164.6.2978","article-title":"CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen","volume":"164","author":"Vremec","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0300","doi-asserted-by":"crossref","unstructured":"S. Alculumbre, S. Raieli, C. Hoffmann, R. Chelbi, F.-X. Danlos, V. Soumelis, Plasmacytoid pre-dendritic cells (pDC): from molecular pathways to function and disease association, Seminars in cell & developmental biology, Elsevier, 2019, pp. 24-35.","DOI":"10.1016\/j.semcdb.2018.02.014"},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0305","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/imm.12504","article-title":"Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus","volume":"146","author":"Mackern-Oberti","year":"2015","journal-title":"Immunology"},{"key":"10.1016\/j.intimp.2024.112077_b0310","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.3389\/fimmu.2017.01765","article-title":"Immunosuppressive effect of B7\u2013H4 pathway in a murine systemic lupus erythematosus model","volume":"8","author":"Xiao","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102856","article-title":"Dendritic cells in systemic lupus erythematosus: From pathogenesis to therapeutic applications","volume":"132","author":"Liu","year":"2022","journal-title":"J. Autoimmun."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-019-1623-0","article-title":"Dendritic cell-associated B7\u2013H3 suppresses the production of autoantibodies and renal inflammation in a mouse model of systemic lupus erythematosus","volume":"10","author":"Zheng","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.intimp.2024.112077_b0325","doi-asserted-by":"crossref","unstructured":"S. Bajana, K. Roach, S. Turner, J. Paul, S. Kovats, IRF4 promotes cutaneous dendritic cell migration to lymph nodes during homeostasis and inflammation, J. Immunol. (Baltimore, Md. : 1950) 189(7) (2012) 3368-77.","DOI":"10.4049\/jimmunol.1102613"},{"key":"10.1016\/j.intimp.2024.112077_b0330","doi-asserted-by":"crossref","unstructured":"M. Akbari, K. Honma, D. Kimura, M. Miyakoda, K. Kimura, T. Matsuyama, K. Yui, IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major, J. Immunol. (Baltimore, Md. : 1950) 192(5) (2014) 2271-9.","DOI":"10.4049\/jimmunol.1301914"},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0335","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nri3470","article-title":"Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks","volume":"13","author":"Murphy","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0340","doi-asserted-by":"crossref","unstructured":"T. Tamura, P. Tailor, K. Yamaoka, H.J. Kong, H. Tsujimura, J.J. O'Shea, H. Singh, K. Ozato, IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity, J. Immunol. (Baltimore, Md. : 1950) 174(5) (2005) 2573-81.","DOI":"10.4049\/jimmunol.174.5.2573"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0345","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.4049\/jimmunol.174.5.2573","article-title":"IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity","volume":"174","author":"Tamura","year":"2005","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0350","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1073\/pnas.93.9.3942","article-title":"Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice","volume":"93","author":"Shipley","year":"1996","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0355","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.immuni.2013.08.028","article-title":"Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells","volume":"39","author":"Gao","year":"2013","journal-title":"Immunity"},{"issue":"44","key":"10.1016\/j.intimp.2024.112077_b0360","doi-asserted-by":"crossref","first-page":"15989","DOI":"10.1073\/pnas.0508327102","article-title":"Negative regulation of Toll-like-receptor signaling by IRF-4","volume":"102","author":"Negishi","year":"2005","journal-title":"PNAS"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0365","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.immuni.2013.04.011","article-title":"IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses","volume":"38","author":"Schlitzer","year":"2013","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0370","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.immuni.2013.03.009","article-title":"IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation","volume":"38","author":"Persson","year":"2013","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0375","doi-asserted-by":"crossref","first-page":"e0141927","DOI":"10.1371\/journal.pone.0141927","article-title":"IRF4-dependent and IRF4-independent pathways contribute to DC dysfunction in lupus","volume":"10","author":"Manni","year":"2015","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0380","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1681\/ASN.2010121260","article-title":"IRF4 deficiency abrogates lupus nephritis despite enhancing systemic cytokine production","volume":"22","author":"Lech","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0385","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1161\/ATVBAHA.112.300173","article-title":"Phenotypic polarization of macrophages in atherosclerosis","volume":"33","author":"Leitinger","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0390","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nri2448","article-title":"Exploring the full spectrum of macrophage activation","volume":"8","author":"Mosser","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0395","doi-asserted-by":"crossref","unstructured":"M. Benoit, B. Desnues, J.L. Mege, Macrophage polarization in bacterial infections, J. Immunol. (Baltimore, Md. : 1950) 181(6) (2008) 3733-9.","DOI":"10.4049\/jimmunol.181.6.3733"},{"issue":"21","key":"10.1016\/j.intimp.2024.112077_b0400","doi-asserted-by":"crossref","first-page":"4111","DOI":"10.1007\/s00018-015-1995-y","article-title":"Macrophage polarization in pathology","volume":"72","author":"Sica","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0405","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.cell.2010.01.022","article-title":"Pattern recognition receptors and inflammation","volume":"140","author":"Takeuchi","year":"2010","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0410","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.autrev.2011.10.010","article-title":"Macrophages and neutrophils in SLE-An online molecular catalog","volume":"11","author":"Orme","year":"2012","journal-title":"Autoimmun. Rev."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0415","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s10067-017-3625-6","article-title":"Macrophage activation syndrome in systemic lupus erythematosus: a multicenter, case-control study in China","volume":"37","author":"Liu","year":"2018","journal-title":"Clin. Rheumatol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0420","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3109\/08830185.2014.969421","article-title":"Cellular metabolism and macrophage functional polarization","volume":"34","author":"Zhu","year":"2015","journal-title":"Int. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0425","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.immuni.2016.09.016","article-title":"Metabolic reprogramming mediated by the mTORC2-IRF4 signaling axis is essential for macrophage alternative activation","volume":"45","author":"Huang","year":"2016","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109264","article-title":"MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages","volume":"35","author":"Bae","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.intimp.2024.112077_b0435","doi-asserted-by":"crossref","unstructured":"D.C. Lacey, A. Achuthan, A.J. Fleetwood, H. Dinh, J. Roiniotis, G.M. Scholz, M.W. Chang, S.K. Beckman, A.D. Cook, J.A. Hamilton, Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models, J. Immunol. (Baltimore, Md. : 1950) 188(11) (2012) 5752-65.","DOI":"10.4049\/jimmunol.1103426"},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0440","doi-asserted-by":"crossref","first-page":"e0208132","DOI":"10.1371\/journal.pone.0208132","article-title":"Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus","volume":"13","author":"Labonte","year":"2018","journal-title":"PLoS One"},{"issue":"26","key":"10.1016\/j.intimp.2024.112077_b0445","doi-asserted-by":"crossref","first-page":"15160","DOI":"10.1073\/pnas.2000943117","article-title":"Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis","volume":"117","author":"Jing","year":"2020","journal-title":"PNAS"},{"issue":"10","key":"10.1016\/j.intimp.2024.112077_b0450","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1038\/ni.1920","article-title":"The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection","volume":"11","author":"Satoh","year":"2010","journal-title":"Nat. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0455","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1159\/000438633","article-title":"TIPE2 Alleviates Systemic Lupus Erythematosus Through Regulating Macrophage Polarization","volume":"38","author":"Li","year":"2016","journal-title":"Cell. Physiol. Biochem."},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0460","doi-asserted-by":"crossref","first-page":"e22628","DOI":"10.1371\/journal.pone.0022628","article-title":"IRF4 is a suppressor of c-Myc induced B cell leukemia","volume":"6","author":"Pathak","year":"2011","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0465","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.smim.2011.08.010","article-title":"The genetic network controlling plasma cell differentiation","volume":"23","author":"Nutt","year":"2011","journal-title":"Semin. Immunol."},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0470","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/ni1357","article-title":"Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination","volume":"7","author":"Klein","year":"2006","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0475","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.immuni.2006.07.009","article-title":"Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation","volume":"25","author":"Sciammas","year":"2006","journal-title":"Immunity"},{"issue":"5299","key":"10.1016\/j.intimp.2024.112077_b0480","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1126\/science.275.5299.540","article-title":"Requirement for the transcription factor LSIRF\/IRF4 for mature B and T lymphocyte function","volume":"275","author":"Mittrucker","year":"1997","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0485","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1089\/107999002753452728","article-title":"The role of IRF-4 in B and T cell activation and differentiation","volume":"22","author":"Pernis","year":"2002","journal-title":"J. Interferon Cytokine Res.: Off. J. Int. Soci. Interferon Cytokine Res."},{"issue":"28","key":"10.1016\/j.intimp.2024.112077_b0490","doi-asserted-by":"crossref","first-page":"9727","DOI":"10.1073\/pnas.0803644105","article-title":"Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors","volume":"105","author":"Mietzner","year":"2008","journal-title":"PNAS"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0495","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.cell.2017.07.026","article-title":"Clonal evolution of autoreactive germinal centers","volume":"170","author":"Degn","year":"2017","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0500","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.immuni.2013.04.009","article-title":"Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4","volume":"38","author":"Ochiai","year":"2013","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0505","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1600-065X.2012.01112.x","article-title":"Roles of BCL6 in normal and transformed germinal center B cells","volume":"247","author":"Basso","year":"2012","journal-title":"Immunol. Rev."},{"issue":"7","key":"10.1016\/j.intimp.2024.112077_b0510","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/ni1478","article-title":"Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR","volume":"8","author":"Ranuncolo","year":"2007","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0515","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0065-2776(10)05007-8","article-title":"BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis","volume":"105","author":"Basso","year":"2010","journal-title":"Adv. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0520","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/nri1572","article-title":"Regulation of plasma-cell development","volume":"5","author":"Shapiro-Shelef","year":"2005","journal-title":"Nat. Rev. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2024.112077_b0525","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.4049\/jimmunol.165.10.5462","article-title":"Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo","volume":"165","author":"Angelin-Duclos","year":"2000","journal-title":"J. Immunol. (Baltimore, Md. : 1950)"},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0530","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13075-018-1578-z","article-title":"Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus","volume":"20","author":"Cole","year":"2018","journal-title":"Arthritis Res. Ther."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0535","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/ni907","article-title":"Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1","volume":"4","author":"Iwakoshi","year":"2003","journal-title":"Nat. Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0540","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1038\/emboj.2009.117","article-title":"XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells","volume":"28","author":"Hu","year":"2009","journal-title":"EMBO J."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0545","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/intimm\/dxx027","article-title":"A transcriptional serenAID: the role of noncoding RNAs in class switch recombination","volume":"29","author":"Yewdell","year":"2017","journal-title":"Int. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0550","doi-asserted-by":"crossref","first-page":"e67003","DOI":"10.1371\/journal.pone.0067003","article-title":"SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature","volume":"8","author":"Becker","year":"2013","journal-title":"PloS One"},{"issue":"10","key":"10.1016\/j.intimp.2024.112077_b0555","doi-asserted-by":"crossref","first-page":"6624","DOI":"10.4049\/jimmunol.178.10.6624","article-title":"A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus","volume":"178","author":"Wei","year":"2007","journal-title":"J. Immunol. (Baltimore, Md. : 1950)"},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0560","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.immuni.2018.08.015","article-title":"Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus","volume":"49","author":"Jenks","year":"2018","journal-title":"Immunity"},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0565","doi-asserted-by":"crossref","first-page":"5009","DOI":"10.1172\/JCI70626","article-title":"Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis","volume":"123","author":"Caganova","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0570","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.4049\/jimmunol.1701470","article-title":"EZH2 represses the B cell transcriptional program and regulates antibody-secreting cell metabolism and antibody production","volume":"200","author":"Guo","year":"2018","journal-title":"J. Immunol. (Baltimore, Md. : 1950)"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0575","doi-asserted-by":"crossref","first-page":"e582","DOI":"10.1097\/HS9.0000000000000582","article-title":"Biology of germinal center B cells relating to lymphomagenesis","volume":"5","author":"Basso","year":"2021","journal-title":"HemaSphere"},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0580","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1182\/bloodadvances.2017010413","article-title":"Zinc finger-IRF composite elements bound by Ikaros\/IRF4 complexes function as gene repression in plasma cell","volume":"2","author":"Ochiai","year":"2018","journal-title":"Blood Adv."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0585","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1172\/JCI78087","article-title":"T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity","volume":"125","author":"Moulton","year":"2015","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2024.112077_b0590","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3389\/fimmu.2015.00610","article-title":"Disturbed T cell signaling and altered Th17 and regulatory T cell subsets in the pathogenesis of systemic lupus erythematosus","volume":"6","author":"Rother","year":"2015","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0595","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1002\/1529-0131(199908)42:8<1644::AID-ANR12>3.0.CO;2-L","article-title":"Th1\/Th2 balance of peripheral T helper cells in systemic lupus erythematosus","volume":"42","author":"Akahoshi","year":"1999","journal-title":"Arthritis Rheum."},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0600","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/cmi.2015.89","article-title":"The regulation of the Treg\/Th17 balance by mesenchymal stem cells in human systemic lupus erythematosus","volume":"14","author":"Wang","year":"2017","journal-title":"Cell. Mol. Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0605","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1016\/j.ymthe.2019.07.014","article-title":"CD8+CD103+ iTregs Inhibit Chronic Graft-versus-Host Disease with Lupus Nephritis by the Increased Expression of CD39","volume":"27","author":"Zhang","year":"2019","journal-title":"Mol. Therapy: J. Am. Soc. Gene Therapy"},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0610","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1093\/nar\/23.12.2127","article-title":"Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)","volume":"23","author":"Matsuyama","year":"1995","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0615","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/ni.2710","article-title":"The transcription factor IRF4 is essential for TCR affinity\u2013mediated metabolic programming and clonal expansion of T cells","volume":"14","author":"Man","year":"2013","journal-title":"Nat. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0620","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.immuni.2013.10.007","article-title":"Interferon regulatory factor 4 sustains CD8+ T cell expansion and effector differentiation","volume":"39","author":"Yao","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2024.112077_b0625","doi-asserted-by":"crossref","unstructured":"R. Nayar, M. Enos, A. Prince, H. Shin, S. Hemmers, J.K. Jiang, U. Klein, C.J. Thomas, L.J. Berg, TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation, Proc. Natl. Acad. Sci. United States of America 109(41) (2012) E2794-802.","DOI":"10.1073\/pnas.1205742109"},{"key":"10.1016\/j.intimp.2024.112077_b0630","doi-asserted-by":"crossref","first-page":"15871","DOI":"10.1038\/ncomms15871","article-title":"ITK signalling via the Ras\/IRF4 pathway regulates the development and function of Tr1 cells","volume":"8","author":"Huang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2024.112077_b0635","article-title":"Targeting kinase ITK treats autoimmune arthritis via orchestrating T cell differentiation and function","volume":"169","author":"Chen","year":"2023","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0640","doi-asserted-by":"crossref","first-page":"e1006597","DOI":"10.1371\/journal.ppat.1006597","article-title":"IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways","volume":"13","author":"Sawada","year":"2017","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0645","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12867-018-0106-7","article-title":"Quantitative profiling of BATF family proteins\/JUNB\/IRF hetero-trimers using Spec-seq","volume":"19","author":"Chang","year":"2018","journal-title":"BMC Mol. Biol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0650","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/s41590-021-00964-8","article-title":"BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells","volume":"22","author":"Seo","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0655","doi-asserted-by":"crossref","unstructured":"BATF and IRF4 Prevent CAR T-cell Exhaustion, Cancer discovery 11(9) (2021) Of9.","DOI":"10.1158\/2159-8290.CD-RW2021-109"},{"key":"10.1016\/j.intimp.2024.112077_b0660","doi-asserted-by":"crossref","first-page":"35521","DOI":"10.1038\/srep35521","article-title":"Interferon Regulatory Factor 4 controls T(H1) cell effector function and metabolism","volume":"6","author":"Mahnke","year":"2016","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.intimp.2024.112077_b0665","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/ni.2710","article-title":"The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells","volume":"14","author":"Man","year":"2013","journal-title":"Nat. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0670","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.4049\/jimmunol.2001184","article-title":"BATF regulates T regulatory cell functional specification and fitness of triglyceride metabolism in restraining allergic responses","volume":"206","author":"Xu","year":"2021","journal-title":"J. Immunol. (Baltimore, Md. : 1950)"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0675","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1365-2796.2009.02099.x","article-title":"Th17 cells in rheumatoid arthritis and systemic lupus erythematosus","volume":"265","author":"Pernis","year":"2009","journal-title":"J. Intern. Med."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0680","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nrrheum.2010.60","article-title":"T cells as therapeutic targets in SLE","volume":"6","author":"Crisp\u00edn","year":"2010","journal-title":"Nat. Rev. Rheumatol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0685","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/08916934.2019.1693545","article-title":"Th1, Th2, and Th17 cytokines in systemic lupus erythematosus","volume":"53","author":"Muhammad Yusoff","year":"2020","journal-title":"Autoimmunity"},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0690","doi-asserted-by":"crossref","first-page":"5227","DOI":"10.1038\/s41598-019-41534-1","article-title":"Inhibition of IL-17 ameliorates systemic lupus erythematosus in Roquinsan\/san mice through regulating the balance of TFH cells, GC B cells, Treg and Breg","volume":"9","author":"Lee","year":"2019","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0695","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1136\/annrheumdis-2019-215356","article-title":"The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies","volume":"78","author":"McGonagle","year":"2019","journal-title":"Ann. Rheum. Dis."},{"issue":"12","key":"10.1016\/j.intimp.2024.112077_b0700","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.4049\/jimmunol.1202254","article-title":"Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4","volume":"191","author":"Gokmen","year":"2013","journal-title":"J. Immunol. (Baltimore, Md. : 1950)"},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0705","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1084\/jem.191.8.1281","article-title":"Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel\/nuclear factor kappaB","volume":"191","author":"Grumont","year":"2000","journal-title":"J. Exp. Med."},{"issue":"8","key":"10.1016\/j.intimp.2024.112077_b0710","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1084\/jem.20011128","article-title":"Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression","volume":"195","author":"Rengarajan","year":"2002","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2024.112077_b0715","doi-asserted-by":"crossref","unstructured":"M. Lohoff, H.W. Mittrucker, S. Prechtl, S. Bischof, F. Sommer, S. Kock, D.A. Ferrick, G.S. Duncan, A. Gessner, T.W. Mak, Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4, Proc. Natl. Acad. Sci. United States of America 99(18) (2002) 11808-12.","DOI":"10.1073\/pnas.182425099"},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0720","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1172\/JCI42856","article-title":"Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice","volume":"120","author":"Biswas","year":"2010","journal-title":"J. Clin. Invest."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0725","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1002\/art.37934","article-title":"Enhanced Rho-Associated Protein Kinase Activation in Patients With Systemic Lupus Erythematosus","volume":"65","author":"Isgro","year":"2013","journal-title":"Arthritis Rheum."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0730","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1136\/annrheumdis-2016-209850","article-title":"Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE","volume":"76","author":"Rozo","year":"2017","journal-title":"Ann. Rheum. Dis."},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0735","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.immuni.2010.05.003","article-title":"Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis","volume":"32","author":"Durant","year":"2010","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0740","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1002\/ibd.21476","article-title":"IRF4 regulates IL-17A promoter activity and controls ROR\u03b3t-dependent Th17 colitis in vivo","volume":"17","author":"Mudter","year":"2011","journal-title":"Inflamm. Bowel Dis."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0745","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1172\/JCI63681","article-title":"IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis","volume":"123","author":"Huber","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"52","key":"10.1016\/j.intimp.2024.112077_b0750","doi-asserted-by":"crossref","first-page":"20846","DOI":"10.1073\/pnas.0809077106","article-title":"IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype","volume":"105","author":"Huber","year":"2008","journal-title":"PNAS"},{"issue":"7421","key":"10.1016\/j.intimp.2024.112077_b0755","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nature11530","article-title":"BATF-JUN is critical for IRF4-mediated transcription in T cells","volume":"490","author":"Li","year":"2012","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.intimp.2024.112077_b0760","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.immuni.2009.03.003","article-title":"Follicular helper T cells: lineage and location","volume":"30","author":"Fazilleau","year":"2009","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0765","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1189\/jlb.0708450","article-title":"IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches","volume":"85","author":"Seo","year":"2009","journal-title":"J. Leukoc. Biol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0770","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.immuni.2008.06.001","article-title":"A fundamental role for interleukin-21 in the generation of T follicular helper cells","volume":"29","author":"Vogelzang","year":"2008","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.intimp.2024.112077_b0775","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/cmi.2012.18","article-title":"The development and function of follicular helper T cells in immune responses","volume":"9","author":"Chen","year":"2012","journal-title":"Cell. Mol. Immunol."},{"issue":"22","key":"10.1016\/j.intimp.2024.112077_b0780","doi-asserted-by":"crossref","first-page":"8664","DOI":"10.1073\/pnas.1205834109","article-title":"Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation","volume":"109","author":"Bollig","year":"2012","journal-title":"PNAS"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0785","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.immuni.2009.10.008","article-title":"Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors","volume":"31","author":"Kwon","year":"2009","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0790","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.immuni.2008.10.011","article-title":"IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor","volume":"29","author":"Chen","year":"2008","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0795","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.autrev.2010.11.004","article-title":"Follicular helper T cells in systemic lupus erythematosus: a potential therapeutic target","volume":"10","author":"Dong","year":"2011","journal-title":"Autoimmun. Rev."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0800","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nrrheum.2012.58","article-title":"Follicular helper T cells in immunity and systemic autoimmunity","volume":"8","author":"Craft","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0805","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.autrev.2010.11.007","article-title":"Follicular helper T cells poise immune responses to the development of autoimmune pathology","volume":"10","author":"Gomez-Martin","year":"2011","journal-title":"Autoimmun. Rev."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0810","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1034\/j.1600-065X.2001.1820102.x","article-title":"Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance","volume":"182","author":"Sakaguchi","year":"2001","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.intimp.2024.112077_b0815","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.3389\/fimmu.2020.01027","article-title":"T cell metabolism: a new perspective on Th17\/Treg cell imbalance in systemic lupus erythematosus","volume":"11","author":"Shan","year":"2020","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0820","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.autrev.2011.09.008","article-title":"Regulatory T cells in systemic lupus erythematosus (SLE); role of peptide tolerance","volume":"11","author":"Sawla","year":"2012","journal-title":"Autoimmun. Rev."},{"issue":"1","key":"10.1016\/j.intimp.2024.112077_b0825","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/08916931003782163","article-title":"Therapeutic potential of TGF-beta-induced CD4(+) Foxp3(+) regulatory T cells in autoimmune diseases","volume":"44","author":"Zhou","year":"2011","journal-title":"Autoimmunity"},{"key":"10.1016\/j.intimp.2024.112077_b0830","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3389\/fimmu.2015.00493","article-title":"FOXP3(+) Treg cells and gender bias in autoimmune diseases","volume":"6","author":"Nie","year":"2015","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112077_b0835","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.it.2012.11.002","article-title":"Differentiation and function of Foxp3+ effector regulatory T cells","volume":"34","author":"Cretney","year":"2013","journal-title":"Trends Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0840","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-981-15-6407-9_1","article-title":"Regulatory T cells: concept, classification, phenotype, and biological characteristics","volume":"1278","author":"Du","year":"2021","journal-title":"Adv. Exp. Med. Biol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112077_b0845","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/ni1500","article-title":"The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4","volume":"8","author":"Brustle","year":"2007","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2024.112077_b0850","unstructured":"(!!! INVALID CITATION !!! [161-163])."},{"issue":"4","key":"10.1016\/j.intimp.2024.112077_b0855","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/ni.2006","article-title":"The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells","volume":"12","author":"Cretney","year":"2011","journal-title":"Nat. Immunol."},{"issue":"7236","key":"10.1016\/j.intimp.2024.112077_b0860","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/nature07674","article-title":"Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses","volume":"458","author":"Zheng","year":"2009","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.intimp.2024.112077_b0865","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1002\/art.39599","article-title":"Regulation of Effector Treg Cells in Murine Lupus","volume":"68","author":"Chandrasekaran","year":"2016","journal-title":"Arthritis Rheumatol. (Hoboken N.J.)"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924005952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924005952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T20:07:29Z","timestamp":1715630849000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924005952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":173,"alternative-id":["S1567576924005952"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112077","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Roles of IRF4 in various immune cells in systemic lupus erythematosus","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112077"}}