{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:25:22Z","timestamp":1787887522493,"version":"build-2784847793"},"reference-count":104,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.intimp.2024.112378","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T23:12:38Z","timestamp":1718233958000},"page":"112378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Preclinical techniques for drug discovery in psoriasis"],"prefix":"10.1016","volume":"137","author":[{"given":"Pranjal P.","family":"Gujarathi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi H.","family":"Korat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piyush S.","family":"Gujarathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2024.112378_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23158575","article-title":"Vitamin D signaling in psoriasis: pathogenesis and therapy","volume":"23","author":"Bro\u017cyna","year":"2022","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms21207488","article-title":"New treatment addressing the pathogenesis of psoriasis","volume":"21","author":"Tokuyama","year":"2020","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15569520500536568","article-title":"Drug-induced psoriasis: An evidence-based overview and the introduction of psoriatic drug eruption probability score","volume":"25","author":"Dika","year":"2006","journal-title":"Cutan. Ocul. Toxicol"},{"key":"10.1016\/j.intimp.2024.112378_b0020","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20184347","article-title":"Risk factors for the development of psoriasis","volume":"20","author":"Kamiya","year":"2019","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0025","doi-asserted-by":"crossref","DOI":"10.14744\/nci.2016.16023","article-title":"A short summary of clinical types of psoriasis","author":"Koca","year":"2016","journal-title":"North. Clin. Istanb"},{"key":"10.1016\/j.intimp.2024.112378_b0030","doi-asserted-by":"crossref","unstructured":"G.W. Kimmel, M. Lebwohl, Psoriasis: Overview and Diagnosis, in: 2018: pp. 1\u201316. 10.1007\/978-3-319-90107-7_1.","DOI":"10.1007\/978-3-319-90107-7_1"},{"key":"10.1016\/j.intimp.2024.112378_b0035","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"The. Lancet"},{"key":"10.1016\/j.intimp.2024.112378_b0040","article-title":"National, regional, and worldwide epidemiology of psoriasis: Systematic analysis and modelling study","volume":"369","author":"Parisi","year":"2020","journal-title":"The. BMJ"},{"key":"10.1016\/j.intimp.2024.112378_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20061475","article-title":"Psoriasis pathogenesis and treatment","volume":"20","author":"Rendon","year":"2019","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0050","unstructured":"C.E. M Griffi ths, J.N. W N Barker, Psoriasis 1 Pathogenesis and clinical features of psoriasis, 2007. www.thelancet.com."},{"key":"10.1016\/j.intimp.2024.112378_b0055","doi-asserted-by":"crossref","unstructured":"C.C. de Alcantara, E.M.V. Reiche, A.N.C. Sim\u00e3o, Cytokines in psoriasis, in: Adv. Clin. Chem., Academic Press Inc., 2021: pp. 171\u2013204. 10.1016\/bs.acc.2020.04.004.","DOI":"10.1016\/bs.acc.2020.04.004"},{"key":"10.1016\/j.intimp.2024.112378_b0060","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18122684","article-title":"Molecular mechanisms and management of a cutaneous inflammatory disorder: Psoriasis","volume":"18","author":"Woo","year":"2017","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0065","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/jid.2011.262","article-title":"Human keratinocytes\u2019 response to injury upregulates CCL20 and other genes linking innate and adaptive immunity","volume":"132","author":"Kennedy-Crispin","year":"2012","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0070","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1007\/s00018-020-03726-1","article-title":"Immune responses and therapeutic options in psoriasis","volume":"78","author":"Afonina","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.intimp.2024.112378_b0075","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222312793","article-title":"The cytokine mediated molecular pathophysiology of psoriasis and its clinical implications","volume":"22","author":"Singh","year":"2021","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0080","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jaut.2015.07.008","article-title":"The immunogenetics of Psoriasis: A comprehensive review","volume":"64","author":"Harden","year":"2015","journal-title":"J. Autoimmun"},{"key":"10.1016\/j.intimp.2024.112378_b0085","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a015354","article-title":"Psoriasis","volume":"4","author":"Di Meglio","year":"2014","journal-title":"Cold. Spring. Harb. Perspect. Med"},{"key":"10.1016\/j.intimp.2024.112378_b0090","first-page":"22","article-title":"Molecular sciences psoriasis: from pathogenesis to pharmacological and nano-technological-based therapeutics","author":"Giron\u00e9s Petit","year":"2021","journal-title":"J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01323","article-title":"The interleukin-23\/interleukin-17 axis links adaptive and innate immunity in psoriasis","volume":"9","author":"Sch\u00f6n","year":"2018","journal-title":"Front. Immunol"},{"key":"10.1016\/j.intimp.2024.112378_b0100","doi-asserted-by":"crossref","first-page":"54","DOI":"10.2340\/00015555-3384","article-title":"Psoriasis and genetics","volume":"100","author":"Dand","year":"2020","journal-title":"Acta. Derm. Venereol"},{"key":"10.1016\/j.intimp.2024.112378_b0105","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1001\/jama.2020.4006","article-title":"Pathophysiology, clinical presentation, and treatment of psoriasis: a review","volume":"323","author":"Armstrong","year":"2020","journal-title":"JAMA - J. Am. Med. Associat."},{"key":"10.1016\/j.intimp.2024.112378_b0110","doi-asserted-by":"crossref","unstructured":"M.J. Jayo, M.D. Zanolli, J.M. Jayo, Psoriatic Plaques in Macaca fascicularis, 1988.","DOI":"10.1177\/030098588802500406"},{"key":"10.1016\/j.intimp.2024.112378_b0115","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/jid.1967.84","article-title":"The histochemistry of the parakeratotic lesion of swine","volume":"48","author":"Anderson","year":"1967","journal-title":"J. Invest. Dermatol"},{"key":"10.1016\/j.intimp.2024.112378_b0120","first-page":"258","article-title":"New approaches to the representationand analysis of phenotype knowledge in human diseases and their animalmodels, Brief Funct","volume":"10","author":"Schofield","year":"2011","journal-title":"Genomics"},{"key":"10.1016\/j.intimp.2024.112378_b0125","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1042\/EBC20160043","article-title":"In vitro skin models and tissue engineering protocols for skin graft applications","volume":"60","author":"Naves","year":"2016","journal-title":"Essays. Biochem"},{"key":"10.1016\/j.intimp.2024.112378_b0130","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1517\/17460441.2013.761202","article-title":"Animal models of skin disease for drug discovery","volume":"8","author":"Avci","year":"2013","journal-title":"Expert. Opin. Drug. Discov"},{"key":"10.1016\/j.intimp.2024.112378_b0135","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1600-0625.2008.00751.x","article-title":"Animal models of psoriasis: A critical appraisal","volume":"17","author":"Sch\u00f6n","year":"2008","journal-title":"Exp. Dermatol"},{"key":"10.1016\/j.intimp.2024.112378_b0140","article-title":"Characterization of Psoriasiform and Alopecic Skin Lesions in HLA-B27 Transgenic Rats Materials and Methods","author":"Yanagisawa","year":"1995","journal-title":"Animals"},{"key":"10.1016\/j.intimp.2024.112378_b0145","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1354\/vp.45-4-563","article-title":"Preclinical models of psoriasis","volume":"45","author":"Danilenko","year":"2008","journal-title":"Vet. Pathol"},{"key":"10.1016\/j.intimp.2024.112378_b0150","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18122514","article-title":"Models in the research process of psoriasis","volume":"18","author":"Boch\u00e9nska","year":"2017","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0155","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1038\/sj.jid.5700807","article-title":"Mouse models of psoriasis","volume":"127","author":"Gudjonsson","year":"2007","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0160","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jid.2021.06.019","article-title":"Mouse models of psoriasis: a comprehensive review","volume":"142","author":"Gangwar","year":"2022","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0165","doi-asserted-by":"crossref","unstructured":"W.J. Josefowicz, M.H. Hardy, The expression of the gene asebia in the laboratory mouse I. Epidermis and dermis, 1978.","DOI":"10.1017\/S0016672300017791"},{"key":"10.1016\/j.intimp.2024.112378_b0170","doi-asserted-by":"crossref","unstructured":"W.R. Brown, M.H. Hardyf, A hypothesis on the cause of chronic epidermal hyperproliferation in asebia mice, 1988.","DOI":"10.1111\/j.1365-2230.1988.tb00661.x"},{"key":"10.1016\/j.intimp.2024.112378_b0175","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1365-2230.1988.tb00691.x","article-title":"Anthralin and tar with UVB increase epidermal cell proliferation in asebia mice","volume":"13","author":"Brown","year":"1988","journal-title":"Clin. Exp. Dermatol"},{"key":"10.1016\/j.intimp.2024.112378_b0180","doi-asserted-by":"crossref","unstructured":"H. Hogenesch, S.E. Torregrosa, D. Boggess, B.A. Sundberg, J. Carroll, J.P. Sundberg, Increased expression of type 2 cytokines in chronic proliferative dermatitis (cpdm) mutant mice and resolution of inflammation following treatment with IL-12, 2001.","DOI":"10.1002\/1521-4141(200103)31:3<734::AID-IMMU734>3.0.CO;2-9"},{"key":"10.1016\/j.intimp.2024.112378_b0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0085666","article-title":"Chronic proliferative dermatitis in Sharpin null mice: Development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4\/IL13 signaling","volume":"9","author":"Potter","year":"2014","journal-title":"PLoS. One"},{"key":"10.1016\/j.intimp.2024.112378_b0190","unstructured":"H. Hogenesch, M.J.J. Gijbels, E. Offerman, J. Van Hooft, D.W. Van Bekkum, C. Zurcher, Animal Model A Spontaneous Mutation Characterized by Chronic Proliferative Dermatitis in C57BL Mice, 1993."},{"key":"10.1016\/j.intimp.2024.112378_b0195","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1038\/sj.emboj.7600183","article-title":"Latent TGF\u03b21 overexpression in keratinocytes results in a severe psoriasis-like skin disorder","volume":"23","author":"Li","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.intimp.2024.112378_b0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/clinem\/dgaa390","article-title":"Nonsurgical management of oligozoospermia","volume":"105","author":"Choy","year":"2020","journal-title":"J. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.intimp.2024.112378_b0205","doi-asserted-by":"crossref","first-page":"6583","DOI":"10.4049\/jimmunol.165.11.6583","article-title":"Cutaneous inflammatory disorder in integrin \u03b1E (CD103)-deficient mice","volume":"165","author":"Sch\u00f6n","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.112378_b0210","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/bies.20047","article-title":"Animal models of T-cell-mediated skin diseases","author":"Zollner","year":"2004","journal-title":"BioEssays"},{"key":"10.1016\/j.intimp.2024.112378_b0215","unstructured":"F. Marashi, L.R. Baumbach Rickles, F.J. Sierra L Stein, G.S. Stein, T.W. Borun, J. Cell Biol, C.L. Thrall, F. Lett, D. Gallwitz, G.C. Mueller, J. Biol Chem, M.D. Scharff, F. Robbins, M. Breindl, B. Biophys, W.D. Park, synthesis of histone proteins in GI HeLa Uninvolved Skin from Psoriatic Patients Develops Signs of Involved Psoriatic Skin After Being Grafted onto Nude Mice, 1966."},{"key":"10.1016\/j.intimp.2024.112378_b0220","unstructured":"G.G. Krueger, D.A. Chambers, J. Shelby, Involved and Uninvolved Skin from Psoriatic Subjects: Are They Equally Diseased? Assessment by skin transplanted to congenitally athymic (NUDE) mice, n.d."},{"key":"10.1016\/j.intimp.2024.112378_b0225","series-title":"Methods in Molecular Biology","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/978-1-4939-6786-5_7","article-title":"Xenotransplantation model of psoriasis","author":"Di Domizio","year":"2017"},{"key":"10.1016\/j.intimp.2024.112378_b0230","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1517\/17460441.1.1.53","article-title":"Humanised mouse models in drug discovery for skin inflammation","volume":"1","author":"Igney","year":"2006","journal-title":"Expert. Opin. Drug. Discov"},{"key":"10.1016\/j.intimp.2024.112378_b0235","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1084\/jem.20031482","article-title":"Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-\u03b1","volume":"199","author":"Boyman","year":"2004","journal-title":"J. Experiment. Med."},{"key":"10.1016\/j.intimp.2024.112378_b0240","doi-asserted-by":"crossref","unstructured":"G.G. Krueger, D.A. Chambers, J. Shelby, Involved and uninvolved skin from psoriatic subjects: are they equally diseased? Assessment by skin transplanted to congenitally athymic (NUDE) mice, 1981.","DOI":"10.1172\/JCI110409"},{"key":"10.1016\/j.intimp.2024.112378_b0245","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1365-2133.2008.08890.x","article-title":"Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model","volume":"160","author":"Stenderup","year":"2009","journal-title":"British J. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0250","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bcp.2016.02.001","article-title":"Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models","volume":"105","author":"Zhang","year":"2016","journal-title":"Biochem. Pharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0255","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1038\/jid.2013.182","article-title":"NF-\u03baB and STAT3 inhibition as a therapeutic strategy in psoriasis: In vitro and in vivo effects of BTH","volume":"133","author":"Andr\u00e9s","year":"2013","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119655","article-title":"Effect of Baricitinib on TPA-induced psoriasis like skin inflammation","volume":"279","author":"Hiraganahalli Bhaskarmurthy","year":"2021","journal-title":"Life. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0265","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23123256","article-title":"Three constituents of moringa oleifera seeds regulate expression of Th17-relevant cytokines and ameliorate tpa-induced psoriasis-like skin lesions in mice","volume":"23","author":"Ma","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.intimp.2024.112378_b0270","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/j.biopha.2016.10.027","article-title":"Evaluation of potent phytomedicine for treatment of psoriasis using UV radiation induced psoriasis in rats","volume":"84","author":"Nagar","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.112378_b0275","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/0253-7613.135949","article-title":"Anti-psoriatic activity of Givotia rottleriformis in rats","volume":"46","author":"Vijayalakshmi","year":"2014","journal-title":"Indian. J. Pharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0280","first-page":"670","article-title":"Imiquimod 5% cream induced psoriasis: A case report, summary of the literature and mechanism","volume":"164","author":"Patel","year":"2011","journal-title":"British J. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0285","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.4049\/jimmunol.0802999","article-title":"Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23\/IL-17 axis","volume":"182","author":"van der Fits","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.112378_b0290","doi-asserted-by":"crossref","DOI":"10.1186\/s13073-017-0415-3","article-title":"Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis","volume":"9","author":"Swindell","year":"2017","journal-title":"Genome. Med"},{"key":"10.1016\/j.intimp.2024.112378_b0295","doi-asserted-by":"crossref","DOI":"10.1038\/srep20134","article-title":"Topical imiquimod yields systemic effects due to unintended oral uptake","volume":"6","author":"Grine","year":"2016","journal-title":"Sci. Rep"},{"key":"10.1016\/j.intimp.2024.112378_b0300","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1111\/jdv.14433","article-title":"The role of IL-23 and the IL-23\/TH17 immune axis in the pathogenesis and treatment of psoriasis","volume":"31","author":"Girolomoni","year":"2017","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.intimp.2024.112378_b0305","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/1744666X.2017.1292137","article-title":"The role of IL 23 in the treatment of psoriasis","volume":"13","author":"Puig","year":"2017","journal-title":"Expert. Rev. Clin. Immunol"},{"key":"10.1016\/j.intimp.2024.112378_b0310","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1084\/jem.20060244","article-title":"IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis","volume":"203","author":"Chan","year":"2006","journal-title":"J. Experiment. Med."},{"key":"10.1016\/j.intimp.2024.112378_b0315","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1016\/j.jid.2017.05.004","article-title":"Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans","volume":"137","author":"Smith","year":"2017","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0320","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.intimp.2016.02.001","article-title":"Oral administration of acarbose ameliorates imiquimod-induced psoriasis-like dermatitis in a mouse model","volume":"33","author":"Chen","year":"2016","journal-title":"Int. Immunopharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0325","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.201","article-title":"Luteolin-7-glucoside inhibits IL-22\/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model","volume":"7","author":"Palombo","year":"2016","journal-title":"Cell. Death. Dis"},{"key":"10.1016\/j.intimp.2024.112378_b0330","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1080\/17460441.2018.1463214","article-title":"Murine models of psoriasis and their usefulness for drug discovery","volume":"13","author":"Chuang","year":"2018","journal-title":"Expert. Opin. Drug. Discov"},{"key":"10.1016\/j.intimp.2024.112378_b0335","doi-asserted-by":"crossref","DOI":"10.1038\/srep16800","article-title":"Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages","volume":"5","author":"Shahraz","year":"2015","journal-title":"Sci. Rep"},{"key":"10.1016\/j.intimp.2024.112378_b0340","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.jid.2021.10.016","article-title":"Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease","volume":"142","author":"Frantz","year":"2022","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0345","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.dci.2019.03.018","article-title":"Models of human psoriasis: Zebrafish the newly appointed player","volume":"97","author":"Mart\u00ednez-Navarro","year":"2019","journal-title":"Dev. Comp. Immunol"},{"key":"10.1016\/j.intimp.2024.112378_b0350","doi-asserted-by":"crossref","first-page":"9507","DOI":"10.3390\/ijms24119507","article-title":"Proteomic and metabolomic changes in psoriasis preclinical and clinical aspects","volume":"24","author":"Radulska","year":"2023","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/9289719","article-title":"The effectiveness and safety of probiotic supplements for psoriasis: a systematic review and meta-analysis of randomized controlled trials and preclinical trials","volume":"2021","author":"Zeng","year":"2021","journal-title":"J. Immunol. Res"},{"key":"10.1016\/j.intimp.2024.112378_b0360","unstructured":"P. Boukamp, R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, N.E. Fusenig, Normal Keratinization in a Spontaneously Immortalized Aneuploid Human Keratinocyte Cell Line, n.d."},{"key":"10.1016\/j.intimp.2024.112378_b0365","unstructured":"A. V Mezentsev, S.A. Bruskin, A.G. Soboleva, V. V Sobolev, E.S. Piruzian, D.E.S. Piruzian, ; Sci, Pharmacological Control of Receptor of Ddvanced Glycation End-Products and its Biological Effects in Psoriasis, 2013. www.ijbs.org."},{"key":"10.1016\/j.intimp.2024.112378_b0370","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jep.2013.07.013","article-title":"Illicium verum extract suppresses IFN-\u03b3-induced ICAM-1 expression via blockade of JAK\/STAT pathway in HaCaT human keratinocytes","volume":"149","author":"Sung","year":"2013","journal-title":"J. Ethnopharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0375","doi-asserted-by":"crossref","unstructured":"H. Uchi, H. Terao, T. Koga, M. Furue, Cytokines and chemokines in the epidermis, 2000. www.elsevier.com\/locate\/jdermsci.","DOI":"10.1016\/S0923-1811(00)00138-9"},{"key":"10.1016\/j.intimp.2024.112378_b0380","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/jid.2012.194","article-title":"The emerging role of IL-17 in the pathogenesis of psoriasis: Preclinical and clinical findings","volume":"133","author":"Martin","year":"2013","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0385","first-page":"1092","article-title":"Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways","volume":"159","author":"Nograles","year":"2008","journal-title":"British J. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0390","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2353\/ajpath.2007.061067","article-title":"The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: Dominance of innate immune responses in psoriasis","volume":"171","author":"Mee","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.intimp.2024.112378_b0395","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/jid.2010.340","article-title":"Integrative responses to IL-17 and TNF-\u03b1 in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis","volume":"131","author":"Chiricozzi","year":"2011","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0400","doi-asserted-by":"crossref","first-page":"32633","DOI":"10.1074\/jbc.M400642200","article-title":"Effects of tumor necrosis factor-\u03b1 (TNF\u03b1) in epidermal keratinocytes revealed using global transcriptional profiling","volume":"279","author":"Banno","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2024.112378_b0405","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/sj.icb.7100078","article-title":"Interleukin-1\u03b1 regulates antimicrobial peptide expression in human keratinocytes","volume":"85","author":"Bando","year":"2007","journal-title":"Immunol. Cell. Biol"},{"key":"10.1016\/j.intimp.2024.112378_b0410","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.3892\/mmr.2016.5825","article-title":"NFB inhibition attenuates LPS-induced TLR4 activation in monocyte cells","volume":"14","author":"Wan","year":"2016","journal-title":"Mol. Med. Rep"},{"key":"10.1016\/j.intimp.2024.112378_b0415","first-page":"268","article-title":"A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions","volume":"8","author":"Duque-Fernandez","year":"2016","journal-title":"Biochem. Biophys. Rep"},{"key":"10.1016\/j.intimp.2024.112378_b0420","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.050541","article-title":"Histological and functional characterization of 3D human skin models mimicking the inflammatory skin diseases psoriasis and atopic dermatitis","volume":"17","author":"Scheurer","year":"2024","journal-title":"Dis. Model. Mech"},{"key":"10.1016\/j.intimp.2024.112378_b0425","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jdermsci.2019.12.010","article-title":"Ex vivo culture of lesional psoriasis skin for pharmacological testing","volume":"97","author":"Tiirikainen","year":"2020","journal-title":"J. Dermatol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0430","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3390\/pharmaceutics12050457","article-title":"Salvianolic acid B in microemulsion formulation provided sufficient hydration for dry skin and ameliorated the severity of imiquimod-induced psoriasis-like dermatitis in mice","volume":"12","author":"Guo","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.intimp.2024.112378_b0435","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/1346-8138.15149","article-title":"Topical administration of nanocarrier miRNA-210 antisense ameliorates imiquimod-induced psoriasis-like dermatitis in mice","volume":"47","author":"Feng","year":"2020","journal-title":"J. Dermatol"},{"key":"10.1016\/j.intimp.2024.112378_b0440","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.3390\/polym12071521","article-title":"Lycopene Inhibit IMQ-Induced Psoriasis-Like Inflammation by Inhibiting ICAM-1 Production in Mice","volume":"12","author":"Shih","year":"2020","journal-title":"Polymers. (basel)"},{"key":"10.1016\/j.intimp.2024.112378_b0445","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2019.110352","article-title":"Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity","volume":"182","author":"Meng","year":"2019","journal-title":"Colloids. Surf. B. Biointerfaces"},{"key":"10.1016\/j.intimp.2024.112378_b0450","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2019.01186","article-title":"Cytokines driven anti-inflammatory and anti-psoriasis like efficacies of nutraceutical sea buckthorn (Hippophae rhamnoides) oil","volume":"10","author":"Balkrishna","year":"2019","journal-title":"Front. Pharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0455","doi-asserted-by":"crossref","first-page":"362","DOI":"10.2174\/2211738507666190906123643","article-title":"Development of Topical Gel of Methotrexate Incorporated Ethosomes and Salicylic Acid for the Treatment of Psoriasis","volume":"7","author":"Chandra","year":"2019","journal-title":"Pharm. Nanotechnol"},{"key":"10.1016\/j.intimp.2024.112378_b0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.172680","article-title":"Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models","volume":"863","author":"Yang","year":"2019","journal-title":"Eur. J. Pharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0465","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109398","article-title":"Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK\/NF-\u03baB\/AP-1 activation","volume":"119","author":"Weng","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.112378_b0470","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1080\/09546634.2020.1789043","article-title":"Mometasone furoate-loaded aspasomal gel for topical treatment of psoriasis: formulation, optimization, in vitro and in vivo performance","volume":"33","author":"Shinde","year":"2022","journal-title":"J. Dermatol. Treatment"},{"key":"10.1016\/j.intimp.2024.112378_b0475","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3390\/ijms21010077","article-title":"Preparation of Calcipotriol Emulsion Using Bacterial Exopolysaccharides as Emulsifier for Percutaneous Treatment of Psoriasis Vulgaris","volume":"21","author":"Song","year":"2019","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0480","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jid.2020.04.031","article-title":"Induction of Regulatory T Cells and Correction of Cytokine Disbalance by Short-Chain Fatty Acids: Implications for Psoriasis Therapy","volume":"141","author":"Schwarz","year":"2021","journal-title":"J. Investigat. Dermatol."},{"key":"10.1016\/j.intimp.2024.112378_b0485","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1186\/s12906-019-2675-5","article-title":"Thymoquinone-loaded lipid vesicles: a promising nanomedicine for psoriasis","volume":"19","author":"Negi","year":"2019","journal-title":"BMC. Complement. Altern. Med"},{"key":"10.1016\/j.intimp.2024.112378_b0490","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.jaci.2019.06.019","article-title":"Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis","volume":"144","author":"Sakurai","year":"2019","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.intimp.2024.112378_b0495","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jconrel.2020.04.038","article-title":"Topical delivery of siRNA into skin using ionic liquids","volume":"323","author":"Dharamdasani","year":"2020","journal-title":"J. Controlled.Release"},{"key":"10.1016\/j.intimp.2024.112378_b0500","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2019.118623","article-title":"Development, characterization and evaluation of topical methotrexate-entrapped deformable liposome on imiquimod-induced psoriasis in a mouse model","volume":"569","author":"Bahramizadeh","year":"2019","journal-title":"Int. J. Pharm"},{"key":"10.1016\/j.intimp.2024.112378_b0505","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1042\/CS20191215","article-title":"Albendazole negatively regulates keratinocyte proliferation","volume":"134","author":"Fusco","year":"2020","journal-title":"Clin. Sci"},{"key":"10.1016\/j.intimp.2024.112378_b0510","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.omtn.2019.11.013","article-title":"Fractional Laser-Mediated siRNA Delivery for Mitigating Psoriasis-like Lesions via IL-6 Silencing","volume":"19","author":"Lee","year":"2020","journal-title":"Mol. Ther. Nucleic. Acids"},{"key":"10.1016\/j.intimp.2024.112378_b0515","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112208","article-title":"Melissa officinalis ssp. altissima extracts: A therapeutic approach targeting psoriasis in mice","volume":"246","author":"Dimitris","year":"2020","journal-title":"J. Ethnopharmacol"},{"key":"10.1016\/j.intimp.2024.112378_b0520","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.113958","article-title":"DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling","volume":"177","author":"Li","year":"2020","journal-title":"Biochem. Pharmacol"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924008981?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924008981?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T15:34:19Z","timestamp":1720280059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924008981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":104,"alternative-id":["S1567576924008981"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112378","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preclinical techniques for drug discovery in psoriasis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112378","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112378"}}