{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T11:21:27Z","timestamp":1771413687443,"version":"3.50.1"},"reference-count":198,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101853"],"award-info":[{"award-number":["82101853"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFF1202903"],"award-info":[{"award-number":["2022YFF1202903"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFF120080"],"award-info":[{"award-number":["2021YFF120080"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.intimp.2024.112446","type":"journal-article","created":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T19:49:40Z","timestamp":1718480980000},"page":"112446","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Decoding the connection between SLE and DNA Sensors: A comprehensive review"],"prefix":"10.1016","volume":"137","author":[{"given":"Yuxiang","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changhuai","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaopeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8268-5781","authenticated-orcid":false,"given":"Wenwei","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0005","first-page":"112","article-title":"DNA sensing in the innate immune response","volume":"35","author":"Briard","year":"2020","journal-title":"Physiology (Bethesda)."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1189\/jlb.0306164","article-title":"DAMPs, PAMPs and alarmins: all we need to know about danger","volume":"81","author":"Bianchi","year":"2007","journal-title":"J. Leukoc. Biol."},{"issue":"9","key":"10.1016\/j.intimp.2024.112446_b0015","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/nri.2016.78","article-title":"Discriminating self from non-self in nucleic acid sensing","volume":"16","author":"Schlee","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0020","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/01.bor.0000127108.08398.34","article-title":"Pattern recognition receptors and their involvement in the pathogenesis of arthritis","volume":"16","author":"Seibl","year":"2004","journal-title":"Curr. Opin. Rheumatol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0025","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0092-8674(00)80412-2","article-title":"Innate immunity: the virtues of a nonclonal system of recognition","volume":"91","author":"Medzhitov","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2024.112446_b0030","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/bs.ircmb.2018.10.002","article-title":"Cytosolic nucleic acid sensors in inflammatory and autoimmune disorders","volume":"344","author":"Khan","year":"2019","journal-title":"Int. Rev. Cell Mol. Biol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0035","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nri1372","article-title":"Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses","volume":"4","author":"Seong","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0040","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3389\/fimmu.2015.00422","article-title":"DAMPs from cell death to new life","volume":"6","author":"V\u00e9n\u00e9reau","year":"2015","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10030532","article-title":"Making sense of intracellular nucleic acid sensing in type I interferon activation in sj\u00f6gren's syndrome","volume":"10","author":"Huijser","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.intimp.2024.112446_b0050","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3389\/fimmu.2013.00440","article-title":"An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology","volume":"4","author":"Ratsimandresy","year":"2013","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0055","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.molcel.2014.03.040","article-title":"The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling","volume":"54","author":"Cai","year":"2014","journal-title":"Mol. Cell"},{"issue":"7152","key":"10.1016\/j.intimp.2024.112446_b0060","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/nature06013","article-title":"DAI (DLM-1\/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response","volume":"448","author":"Takaoka","year":"2007","journal-title":"Nature"},{"issue":"7130","key":"10.1016\/j.intimp.2024.112446_b0065","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1038\/nature05663","article-title":"Pathogenesis and therapy of psoriasis","volume":"445","author":"Lowes","year":"2007","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0070","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.humimm.2019.02.013","article-title":"The role of ERAP1 in autoinflammation and autoimmunity","volume":"80","author":"Pepelyayeva","year":"2019","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0075","article-title":"Inflammasome and its therapeutic targeting in rheumatoid arthritis","volume":"12","author":"Jiang","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0080","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13075-021-02694-6","article-title":"Salivary anti-nuclear antibody (ANA) mirrors serum ANA in systemic lupus erythematosus","volume":"24","author":"Zhang","year":"2022","journal-title":"Arthritis Res. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0085","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13075-019-2029-1","article-title":"Performance of cytokine models in predicting SLE activity","volume":"21","author":"Ruchakorn","year":"2019","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.intimp.2024.112446_b0090","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.clim.2019.05.004","article-title":"Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE","volume":"205","author":"Ye","year":"2019","journal-title":"Clin. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0095","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1177\/0961203311434938","article-title":"Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLE","volume":"21","author":"Ahlin","year":"2012","journal-title":"Lupus"},{"key":"10.1016\/j.intimp.2024.112446_b0100","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3389\/fimmu.2015.00291","article-title":"Animal models of interferon signature positive lupus","volume":"6","author":"Zhuang","year":"2015","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0105","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/ard.2005.038315","article-title":"Raised plasma concentration and ex vivo production of inflammatory chemokines in patients with systemic lupus erythematosus","volume":"65","author":"Lit","year":"2006","journal-title":"Ann. Rheum. Dis."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00251-020-01158-6","article-title":"Differential expression of the inflammasome complex genes in systemic lupus erythematosus","volume":"72","author":"da Cruz","year":"2020","journal-title":"Immunogenetics"},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0115","doi-asserted-by":"crossref","first-page":"5459","DOI":"10.4049\/jimmunol.1002795","article-title":"Type I interferon in the pathogenesis of lupus","volume":"192","author":"Crow","year":"2014","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0120","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/rheumatology\/keu318","article-title":"Sex-dependent differential activation of NLRP3 and AIM2 inflammasomes in SLE macrophages","volume":"54","author":"Yang","year":"2015","journal-title":"Rheumatology (Oxford)"},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0125","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1182\/blood-2011-08-371831","article-title":"The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor \u03b1 signaling","volume":"119","author":"Seillet","year":"2012","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0130","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s10875-013-9881-6","article-title":"AIM2 facilitates the apoptotic DNA-induced systemic lupus erythematosus via arbitrating macrophage functional maturation","volume":"33","author":"Zhang","year":"2013","journal-title":"J. Clin. Immunol."},{"issue":"19","key":"10.1016\/j.intimp.2024.112446_b0135","doi-asserted-by":"crossref","first-page":"13534","DOI":"10.1074\/jbc.M113.457218","article-title":"DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway","volume":"288","author":"Zhang","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2024.112446_b0140","article-title":"Identification and validation of IFI44 as key biomarker in lupus nephritis","volume":"8","author":"Shen","year":"2021","journal-title":"Front Med (Lausanne)."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0145","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1172\/JCI23025","article-title":"Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9","volume":"115","author":"Means","year":"2005","journal-title":"J. Clin. Invest."},{"issue":"3 Pt A","key":"10.1016\/j.intimp.2024.112446_b0150","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.jid.2021.04.037","article-title":"Photosensitivity and cGAS-dependent IFN-1 activation in patients with lupus and TREX1 deficiency","volume":"142","author":"Berndt","year":"2022","journal-title":"J, Invest. Dermatol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0155","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/imr.12901","article-title":"The microbiome and cytosolic innate immune receptors","volume":"297","author":"Liwinski","year":"2020","journal-title":"Immunol. Rev."},{"issue":"6121","key":"10.1016\/j.intimp.2024.112446_b0160","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1126\/science.1232458","article-title":"Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway","volume":"339","author":"Sun","year":"2013","journal-title":"Science"},{"issue":"6403","key":"10.1016\/j.intimp.2024.112446_b0165","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1126\/science.aat1022","article-title":"DNA-induced liquid phase condensation of cGAS activates innate immune signaling","volume":"361","author":"Du","year":"2018","journal-title":"Science"},{"issue":"24","key":"10.1016\/j.intimp.2024.112446_b0170","doi-asserted-by":"crossref","first-page":"11946","DOI":"10.1073\/pnas.1905013116","article-title":"Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation","volume":"116","author":"Xie","year":"2019","journal-title":"PNAS"},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0175","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.cell.2018.06.026","article-title":"Structure of the human cGAS-DNA complex reveals enhanced control of immune surveillance","volume":"174","author":"Zhou","year":"2018","journal-title":"Cell"},{"issue":"7454","key":"10.1016\/j.intimp.2024.112446_b0180","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nature12306","article-title":"cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING","volume":"498","author":"Ablasser","year":"2013","journal-title":"Nature"},{"issue":"7213","key":"10.1016\/j.intimp.2024.112446_b0185","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/nature07317","article-title":"STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling","volume":"455","author":"Ishikawa","year":"2008","journal-title":"Nature"},{"issue":"21","key":"10.1016\/j.intimp.2024.112446_b0190","doi-asserted-by":"crossref","first-page":"8653","DOI":"10.1073\/pnas.0900850106","article-title":"ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization","volume":"106","author":"Sun","year":"2009","journal-title":"PNAS"},{"issue":"7747","key":"10.1016\/j.intimp.2024.112446_b0195","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/s41586-019-1006-9","article-title":"Autophagy induction via STING trafficking is a primordial function of the cGAS pathway","volume":"567","author":"Gui","year":"2019","journal-title":"Nature"},{"issue":"7748","key":"10.1016\/j.intimp.2024.112446_b0200","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/s41586-019-1000-2","article-title":"Structural basis of STING binding with and phosphorylation by TBK1","volume":"567","author":"Zhang","year":"2019","journal-title":"Nature"},{"issue":"6227","key":"10.1016\/j.intimp.2024.112446_b0205","doi-asserted-by":"crossref","first-page":"aaa2630","DOI":"10.1126\/science.aaa2630","article-title":"Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation","volume":"347","author":"Liu","year":"2015","journal-title":"Science"},{"issue":"214","key":"10.1016\/j.intimp.2024.112446_b0210","doi-asserted-by":"crossref","first-page":"ra20","DOI":"10.1126\/scisignal.2002521","article-title":"STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway","volume":"5","author":"Tanaka","year":"2012","journal-title":"Sci. Signal."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0215","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.immuni.2018.07.008","article-title":"Non-canonical NF-\u03baB antagonizes STING sensor-mediated DNA sensing in radiotherapy","volume":"49","author":"Hou","year":"2018","journal-title":"Immunity"},{"issue":"10","key":"10.1016\/j.intimp.2024.112446_b0220","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1136\/annrheumdis-2018-212988","article-title":"Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus","volume":"77","author":"Kato","year":"2018","journal-title":"Ann. Rheum. Dis."},{"issue":"10","key":"10.1016\/j.intimp.2024.112446_b0225","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1093\/rheumatology\/keaa060","article-title":"Inhibition of mTOR suppresses IFNalpha production and the STING pathway in monocytes from systemic lupus erythematosus patients","volume":"59","author":"Murayama","year":"2020","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.intimp.2024.112446_b0230","doi-asserted-by":"crossref","first-page":"11752","DOI":"10.1038\/ncomms11752","article-title":"RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA","volume":"7","author":"Wolf","year":"2016","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0235","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.cell.2007.10.017","article-title":"Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease","volume":"131","author":"Yang","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2024.112446_b0240","doi-asserted-by":"crossref","unstructured":"Gao DX, Li T, Li XD, Chen X, Li QZ, Wight-Carter M, et al. Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 112 (42) (2015) E5699-E5705 DOI: 10.1073\/pnas.1516465112.","DOI":"10.1073\/pnas.1516465112"},{"key":"10.1016\/j.intimp.2024.112446_b0245","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jtauto.2020.100075","article-title":"Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fc\u03b3 receptor IIb in non-autoimmune-prone and SLE-prone mice","volume":"4","author":"Chu","year":"2021","journal-title":"J Transl Autoimmun."},{"key":"10.1016\/j.intimp.2024.112446_b0250","doi-asserted-by":"crossref","first-page":"31617","DOI":"10.1038\/srep31617","article-title":"Comprehensive assessment of the association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: evidence from a meta-analysis","volume":"6","author":"Zhu","year":"2016","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.intimp.2024.112446_b0255","doi-asserted-by":"crossref","first-page":"7186","DOI":"10.4049\/jimmunol.172.11.7186","article-title":"A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing Fc\u03b3RIIb alters receptor expression and associates with autoimmunity.: I.: regulatory <i>FCGR2B<\/i> polymorphisms and their association with systemic lupus erythematosus","volume":"172","author":"Su","year":"2004","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0260","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ajhg.2014.12.003","article-title":"CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease","volume":"96","author":"Strauss","year":"2015","journal-title":"Am. J. Hum. Genet."},{"issue":"23","key":"10.1016\/j.intimp.2024.112446_b0265","doi-asserted-by":"crossref","first-page":"4409","DOI":"10.1111\/bph.14045","article-title":"Lon protease: a novel mitochondrial matrix protein in the interconnection between drug-induced mitochondrial dysfunction and endoplasmic reticulum stress","volume":"174","author":"Polo","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.intimp.2024.112446_b0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110519","article-title":"Mitochondrial Lon protease promotes CD4(+) T cell activation by activating the cGAS-STING-TBK1 axis in systemic lupus erythematosus","volume":"123","author":"Huang","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"15","key":"10.1016\/j.intimp.2024.112446_b0275","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1093\/hmg\/ddad062","article-title":"Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT","volume":"32","author":"Al Khatib","year":"2023","journal-title":"Hum. Mol. Genet."},{"issue":"17","key":"10.1016\/j.intimp.2024.112446_b0280","doi-asserted-by":"crossref","first-page":"4464","DOI":"10.1016\/j.cell.2021.07.021","article-title":"Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE","volume":"184","author":"Caielli","year":"2021","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0285","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/MOH.0000000000000134","article-title":"Human and murine erythropoiesis","volume":"22","author":"An","year":"2015","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.intimp.2024.112446_b0290","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.mehy.2018.09.015","article-title":"In lupus nephritis, how do extracellular DNAs trigger type I interferon secretion: under the assistance of HMGB1-cGAS?","volume":"121","author":"Zheng","year":"2018","journal-title":"Med. Hypotheses"},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/abbi.2000.1773","article-title":"The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis","volume":"377","author":"Boiteux","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0300","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/art.39987","article-title":"Ultraviolet B irradiation causes stimulator of interferon genes-dependent production of protective type I interferon in mouse skin by recruited inflammatory monocytes","volume":"69","author":"Sontheimer","year":"2017","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.intimp.2024.112446_b0305","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.554725","article-title":"Oxidative DNA damage accelerates skin inflammation in pristane-induced lupus model","volume":"11","author":"Tumurkhuu","year":"2020","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0310","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s10875-015-0147-3","article-title":"Human disease phenotypes associated with mutations in TREX1","volume":"35","author":"Rice","year":"2015","journal-title":"J. Clin. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0315","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/cei\/uxad017","article-title":"TREX1 cytosolic DNA degradation correlates with autoimmune disease and cancer immunity","volume":"211","author":"Fang","year":"2023","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0320","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jaut.2019.03.001","article-title":"cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model","volume":"100","author":"Xiao","year":"2019","journal-title":"J. Autoimmun."},{"issue":"11","key":"10.1016\/j.intimp.2024.112446_b0325","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1038\/s41419-021-04323-1","article-title":"A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus","volume":"12","author":"Tang","year":"2021","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0330","doi-asserted-by":"crossref","first-page":"e1006156","DOI":"10.1371\/journal.ppat.1006156","article-title":"SENP7 potentiates cGAS activation by relieving SUMO-mediated inhibition of cytosolic DNA sensing","volume":"13","author":"Cui","year":"2017","journal-title":"PLoS Pathog."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0335","doi-asserted-by":"crossref","first-page":"e1006264","DOI":"10.1371\/journal.ppat.1006264","article-title":"The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response","volume":"13","author":"Wang","year":"2017","journal-title":"PLoS Pathog."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0340","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.celrep.2020.108297","article-title":"MYSM1 represses innate immunity and autoimmunity through suppressing the cGAS-STING pathway","volume":"33","author":"Tian","year":"2020","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.intimp.2024.112446_b0345","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1038\/s41423-021-00758-w","article-title":"Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases","volume":"18","author":"Hou","year":"2021","journal-title":"Cell. Mol. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0350","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1002\/art.40576","article-title":"Association of abnormal elevations in IFIT3 With overactive cyclic GMP-AMP synthase\/stimulator of interferon genes signaling in human systemic lupus erythematosus monocytes","volume":"70","author":"Wang","year":"2018","journal-title":"Arthritis Rheumatol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0355","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1002\/art.23407","article-title":"Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis","volume":"58","author":"Savarese","year":"2008","journal-title":"Arthritis Rheum."},{"issue":"13","key":"10.1016\/j.intimp.2024.112446_b0360","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1084\/jem.20080462","article-title":"TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus","volume":"205","author":"Lee","year":"2008","journal-title":"J. Exp. Med."},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0365","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1420217112","article-title":"Suppression of systemic autoimmunity by the innate immune adaptor STING","volume":"112","author":"Sharma","year":"2015","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2024.112446_b0370","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.605930","article-title":"cGAS-STING pathway does not promote autoimmunity in murine models of SLE","volume":"12","author":"Motwani","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0375","doi-asserted-by":"crossref","first-page":"1010764","DOI":"10.3389\/fimmu.2022.1010764","article-title":"cGAS deficiency enhances inflammasome activation in macrophages and inflammatory pathology in pristane-induced lupus","volume":"13","author":"Kumpunya","year":"2022","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0380","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.chom.2011.04.008","article-title":"IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection","volume":"9","author":"Kerur","year":"2011","journal-title":"Cell Host Microbe"},{"issue":"7991","key":"10.1016\/j.intimp.2024.112446_b0385","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/s41586-023-06742-w","article-title":"Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome","volume":"624","author":"Shi","year":"2023","journal-title":"Nature"},{"issue":"suppl_1","key":"10.1016\/j.intimp.2024.112446_b0390","first-page":"i88","article-title":"Modelling clinical systemic lupus erythematosus: similarities, differences and success stories","volume":"56","author":"Celhar","year":"2017","journal-title":"Rheumatology (Oxford)"},{"issue":"11","key":"10.1016\/j.intimp.2024.112446_b0395","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1002\/art.40559","article-title":"Inhibition of cyclic GMP-AMP synthase using a novel antimalarial drug derivative in Trex1-deficient mice","volume":"70","author":"An","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.intimp.2024.112446_b0400","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fphar.2020.00088","article-title":"Compound C reducing interferon expression by inhibiting cGAMP accumulation","volume":"11","author":"Lai","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0405","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1002\/eji.201747338","article-title":"Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes","volume":"48","author":"Steinhagen","year":"2018","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0410","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103314","article-title":"A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology","volume":"66","author":"Prabakaran","year":"2021","journal-title":"EBioMedicine"},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0415","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/15548627.2023.2256135","article-title":"CSNK1A1\/CK1a suppresses autoimmunity by restraining the CGAS-STING1 signaling","volume":"20","author":"Pan","year":"2024","journal-title":"Autophagy"},{"issue":"6813","key":"10.1016\/j.intimp.2024.112446_b0420","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/35047123","article-title":"A Toll-like receptor recognizes bacterial DNA","volume":"408","author":"Hemmi","year":"2000","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0425","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1084\/jem.192.4.595","article-title":"Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6","volume":"192","author":"H\u00e4cker","year":"2000","journal-title":"J. Exp. Med."},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0430","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1084\/jem.20061523","article-title":"Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor- mediated immune responses but not in TCR signaling","volume":"204","author":"Kawagoe","year":"2007","journal-title":"J. Exp. Med."},{"issue":"6844","key":"10.1016\/j.intimp.2024.112446_b0435","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/35085597","article-title":"TAK1 is a ubiquitin-dependent kinase of MKK and IKK","volume":"412","author":"Wang","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2024.112446_b0440","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/978-1-4939-3335-8_16","article-title":"Toll-like receptor-dependent immune complex activation of B cells and dendritic cells","volume":"1390","author":"Moody","year":"2016","journal-title":"Methods in Molecular Biology (Clifton, NJ)."},{"key":"10.1016\/j.intimp.2024.112446_b0445","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1155\/2014\/381418","article-title":"Expression of toll-like receptors 3, 7, and 9 in peripheral blood mononuclear cells from patients with systemic lupus erythematosus","volume":"2014","author":"Klonowska-Szymczyk","year":"2014","journal-title":"Mediat Inflamm."},{"key":"10.1016\/j.intimp.2024.112446_b0450","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jaut.2019.05.002","article-title":"Transitional B cells in quiescent SLE: an early checkpoint imprinted by IFN","volume":"102","author":"Dieudonn\u00e9","year":"2019","journal-title":"J. Autoimmun."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0455","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s13075-014-0477-1","article-title":"Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation","volume":"16","author":"Sieber","year":"2014","journal-title":"Arthritis Res. Ther."},{"issue":"16","key":"10.1016\/j.intimp.2024.112446_b0460","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1172\/jci.insight.172219","article-title":"B cell-intrinsic TLR7 expression drives severe lupus in TLR9-deficient mice","volume":"8","author":"Cosgrove","year":"2023","journal-title":"Jci Insight."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0465","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1172\/JCI132328","article-title":"B cell-intrinsic TLR9 expression is protective in murine lupus","volume":"130","author":"Tilstra","year":"2020","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2024.112446_b0470","doi-asserted-by":"crossref","unstructured":"Desnues B, Macedo AB, Roussel-Queval A, Bonnardel J, Henri S, Demaria O, et al. TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL\/6 mice. Proceedings of the National Academy of Sciences of the United States of America. 111 (4) (2014) 1497-1502 DOI: 10.1073\/pnas.1314121111.","DOI":"10.1073\/pnas.1314121111"},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0475","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.immuni.2011.05.010","article-title":"Unc93B1 restricts systemic lethal inflammation by orchestrating toll-like receptor 7 and 9 trafficking","volume":"35","author":"Fukui","year":"2011","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0480","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1074-7613(00)80418-5","article-title":"The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity","volume":"6","author":"Tedder","year":"1997","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0485","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1172\/jci.insight.96795","article-title":"Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus","volume":"3","author":"Gies","year":"2018","journal-title":"Jci Insight."},{"key":"10.1016\/j.intimp.2024.112446_b0490","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jaut.2020.102582","article-title":"The B cell response to both protein and nucleic acid antigens displayed on apoptotic cells are dependent on endosomal pattern recognition receptors","volume":"117","author":"Garimella","year":"2021","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.intimp.2024.112446_b0495","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jaut.2014.02.005","article-title":"TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response","volume":"51","author":"Guerrier","year":"2014","journal-title":"J. Autoimmun."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0500","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/ar4087","article-title":"Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity","volume":"14","author":"Tanaka","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.intimp.2024.112446_b0505","first-page":"18","article-title":"Pyruvate kinase M2 contributes to TLR-mediated inflammation and autoimmunity by promoting Pyk2 activation","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0510","series-title":"Autoimmunity: Concepts and Diagnosis at the Cutting Edge","first-page":"34","article-title":"BAFF overexpression is associated with autoantibody production in autoimmune diseases","author":"Pers","year":"2005"},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0515","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/rheumatology\/ket006","article-title":"Toll-like receptor 9 activation induces expression of membrane-bound B-cell activating factor (BAFF) on human B cells and leads to increased proliferation in response to both soluble and membrane-bound BAFF","volume":"52","author":"Abu-Rish","year":"2013","journal-title":"Rheumatology"},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0520","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1002\/eji.201445286","article-title":"TLR9-induced miR-155 and Ets-1 decrease expression of CD1d on B cells in SLE","volume":"45","author":"Liu","year":"2015","journal-title":"Eur. J. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0525","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1002\/emmm.201201595","article-title":"Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity","volume":"4","author":"Schickel","year":"2012","journal-title":"EMBO Mol. Med."},{"issue":"73","key":"10.1016\/j.intimp.2024.112446_b0530","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1126\/scitranslmed.3001201","article-title":"Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus","volume":"3","author":"Garcia-Romo","year":"2011","journal-title":"Sci. Transl. Med."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0535","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/ni.3326","article-title":"Self-reactive IgE exacerbates interferon responses associated with autoimmunity","volume":"17","author":"Henault","year":"2016","journal-title":"Nat. Immunol."},{"issue":"5421","key":"10.1016\/j.intimp.2024.112446_b0540","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1126\/science.284.5421.1835","article-title":"The nature of the principal type 1 interferon-producing cells in human blood","volume":"284","author":"Siegal","year":"1999","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0545","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1136\/annrheumdis-2012-203041","article-title":"TLR9 independent interferon \u03b1 production by neutrophils on NETosis in response to circulating chromatin, a key lupus autoantigen","volume":"73","author":"Lindau","year":"2014","journal-title":"Ann. Rheum. Dis."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0550","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/imm.13379","article-title":"Neutralizing interferon-\u03b1 blocks inflammation-mediated vascular injury via PI3K and AMPK in systemic lupus erythematosus","volume":"164","author":"Ding","year":"2021","journal-title":"Immunology"},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0555","doi-asserted-by":"crossref","first-page":"1022-+","DOI":"10.1016\/j.immuni.2020.04.015","article-title":"Plasmacytoid dendritic cells and type I interferon promote extrafollicular B cell responses to extracellular self-DNA","volume":"52","author":"Soni","year":"2020","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0560","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.coi.2013.10.006","article-title":"TLRs and interferons: a central paradigm in autoimmunity","volume":"25","author":"Kono","year":"2013","journal-title":"Curr. Opin. Immunol."},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0565","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1136\/ard.2006.065961","article-title":"Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population","volume":"66","author":"Tao","year":"2007","journal-title":"Ann. Rheum. Dis."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0575","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1002\/kjm2.12769","article-title":"TLR9 regulates the autophagy-lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6-cGAS-STING pathway","volume":"39","author":"Liu","year":"2023","journal-title":"Kaohsiung J. Med. Sci."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0580","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1038\/ni1411","article-title":"The TREM receptor family and signal integration","volume":"7","author":"Klesney-Tait","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0585","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jaut.2016.12.010","article-title":"Triggering receptor expressed on myeloid cells-1 (TREM-1) deficiency augments BAFF production to promote lupus progression","volume":"78","author":"Liu","year":"2017","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0590","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/cmi.2015.61","article-title":"Ligation of CD180 inhibits IFN-\u03b1 signaling in a Lyn-PI3K-BTK-dependent manner in B cells","volume":"14","author":"You","year":"2017","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0595","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.3389\/fimmu.2018.02643","article-title":"CD180 ligation inhibits TLR7- and TLR9-mediated activation of macrophages and dendritic cells through the lyn-SHP-1\/2 axis in murine lupus","volume":"9","author":"Yang","year":"2018","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0600","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jaut.2009.11.001","article-title":"Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice","volume":"34","author":"Santiago-Raber","year":"2010","journal-title":"J. Autoimmun."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0605","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1084\/jem.20082316","article-title":"Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing","volume":"206","author":"Fukui","year":"2009","journal-title":"J. Exp. Med."},{"issue":"92","key":"10.1016\/j.intimp.2024.112446_b0610","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1126\/sciimmunol.adi9769","article-title":"UNC93B1 variants underlie TLR7-dependent autoimmunity","volume":"9","author":"Wolf","year":"2024","journal-title":"Sci. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112446_b0615","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1371\/journal.pone.0070626","article-title":"Multiple sclerosis: modulation of Toll-Like Receptor (TLR) expression by interferon-\u03b2 includes upregulation of TLR7 in plasmacytoid dendritic cells","volume":"8","author":"Derkow","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2024.112446_b0620","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13075-017-1441-7","article-title":"Enhanced IFN-\u03b1 production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus","volume":"19","author":"Murayama","year":"2017","journal-title":"Arthritis Res. Ther."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0625","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/ar3075","article-title":"Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus","volume":"12","author":"Jin","year":"2010","journal-title":"Arthritis Res. Ther."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0630","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jaut.2006.06.005","article-title":"Regulatory T cells in patients with systemic lupus erythematosus","volume":"27","author":"Alvarado-S\u00e1nchez","year":"2006","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0635","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.clim.2013.03.003","article-title":"Sexual disparities in the incidence and course of SLE and RA","volume":"149","author":"Tedeschi","year":"2013","journal-title":"Clin. Immunol."},{"issue":"1\u20132","key":"10.1016\/j.intimp.2024.112446_b0640","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cellimm.2012.07.007","article-title":"17\u03b2-Estradiol enhances response of mice spleen B cells elicited by TLR9 agonist","volume":"278","author":"Xu","year":"2012","journal-title":"Cell. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0645","doi-asserted-by":"crossref","first-page":"5561","DOI":"10.4049\/jimmunol.1500315","article-title":"Estrogen receptor \u03b1 deficiency modulates TLR ligand-mediated PDC-TREM expression in plasmacytoid dendritic cells in lupus-prone mice","volume":"195","author":"Scott","year":"2015","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0650","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13293-023-00495-x","article-title":"Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-\u03b1 in women in response to TLR9 in humans","volume":"14","author":"Beisel","year":"2023","journal-title":"Biol. Sex Differ."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0655","doi-asserted-by":"crossref","first-page":"R155","DOI":"10.1186\/ar3895","article-title":"Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus","volume":"14","author":"Sacre","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.intimp.2024.112446_b0660","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102894","article-title":"SB431542 alleviates lupus nephritis by regulating B cells and inhibiting the TLR9\/TGF\u03b21\/PDGFB signaling","volume":"132","author":"Xia","year":"2022","journal-title":"J. Autoimmun."},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0665","doi-asserted-by":"crossref","DOI":"10.3390\/cells9071648","article-title":"A novel small-molecule inhibitor of endosomal TLRs reduces inflammation and alleviates autoimmune disease symptoms in murine models","volume":"9","author":"Patra","year":"2020","journal-title":"Cells."},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0670","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4078\/jrd.2021.28.3.133","article-title":"Intravenous administration of toll-like receptor inhibitory peptide 1 is effective for the treatment of systemic lupus erythematosus in a mus musculus model","volume":"28","author":"Baek","year":"2021","journal-title":"J Rheum Dis."},{"issue":"24","key":"10.1016\/j.intimp.2024.112446_b0675","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232416030","article-title":"Amelioration of lupus symptoms in mice via blockade of TLR7\/9's signal","volume":"23","author":"Wang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0680","doi-asserted-by":"crossref","first-page":"3582","DOI":"10.1002\/eji.200737815","article-title":"Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms","volume":"37","author":"Barrat","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0685","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116283","article-title":"Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9\/MyD88 activation","volume":"309","author":"He","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0690","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s13075-023-03186-5","article-title":"Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus","volume":"25","author":"Yasaka","year":"2023","journal-title":"Arthritis Res. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0695","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s12943-022-01687-6","article-title":"Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling","volume":"21","author":"Rizzello","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.intimp.2024.112446_b0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102858","article-title":"GILZ regulates type I interferon release and sequesters STAT1","volume":"131","author":"Nataraja","year":"2022","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0705","doi-asserted-by":"crossref","first-page":"e0244439","DOI":"10.1371\/journal.pone.0244439","article-title":"The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models","volume":"16","author":"Katewa","year":"2021","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.intimp.2024.112446_b0710","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/s41423-019-0254-9","article-title":"BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells","volume":"17","author":"Georg","year":"2020","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0715","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1600-065X.2011.01053.x","article-title":"The PYHIN protein family as mediators of host defenses","volume":"243","author":"Schattgen","year":"2011","journal-title":"Immunol. Rev."},{"issue":"5917","key":"10.1016\/j.intimp.2024.112446_b0720","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1126\/science.1169841","article-title":"HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA","volume":"323","author":"Roberts","year":"2009","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0725","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.bbrc.2004.12.056","article-title":"The HIN domain of IFI-200 proteins consists of two OB folds","volume":"327","author":"Albrecht","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0730","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.immuni.2012.02.014","article-title":"Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor","volume":"36","author":"Jin","year":"2012","journal-title":"Immunity"},{"issue":"Pt 1","key":"10.1016\/j.intimp.2024.112446_b0735","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1107\/S2053230X1303135X","article-title":"Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling","volume":"70","author":"Li","year":"2014","journal-title":"Acta. Crystallogr. F Struct. Biol. Commun."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0740","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.bcmd.2003.10.002","article-title":"The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation","volume":"32","author":"Asefa","year":"2004","journal-title":"Blood Cell Mol. Dis."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0745","doi-asserted-by":"crossref","first-page":"7385","DOI":"10.4049\/jimmunol.1002468","article-title":"Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus","volume":"185","author":"Panchanathan","year":"2010","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0750","doi-asserted-by":"crossref","first-page":"6762","DOI":"10.4049\/jimmunol.1003638","article-title":"Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein","volume":"186","author":"Panchanathan","year":"2011","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2024.112446_b0755","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201845737","article-title":"Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16","volume":"19","author":"Wang","year":"2018","journal-title":"EMBO Rep."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0760","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.mehy.2015.09.026","article-title":"The regional function of cGAS\/STING signal in multiple organs: one of culprit behind systemic lupus erythematosus?","volume":"85","author":"Ding","year":"2015","journal-title":"Med. Hypotheses"},{"issue":"2","key":"10.1016\/j.intimp.2024.112446_b0765","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1101\/gr.100289.109","article-title":"Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus","volume":"20","author":"Javierre","year":"2010","journal-title":"Genome Res."},{"issue":"1\u20132","key":"10.1016\/j.intimp.2024.112446_b0770","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.molimm.2012.06.013","article-title":"Murine BAFF expression is up-regulated by estrogen and interferons: implications for sex bias in the development of autoimmunity","volume":"53","author":"Panchanathan","year":"2013","journal-title":"Mol. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0775","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00944-17","article-title":"AIM2-like receptors positively and negatively regulate the interferon response induced by cytosolic DNA","volume":"8","author":"Nakaya","year":"2017","journal-title":"MBio"},{"issue":"9","key":"10.1016\/j.intimp.2024.112446_b0780","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/rheumatology\/keh656","article-title":"Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA","volume":"44","author":"Qiao","year":"2005","journal-title":"Rheumatology (Oxford)"},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0785","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1093\/rheumatology\/kem275","article-title":"DNA hypomethylation is crucial for apoptotic DNA to induce systemic lupus erythematosus-like autoimmune disease in SLE-non-susceptible mice","volume":"46","author":"Wen","year":"2007","journal-title":"Rheumatology (Oxford)"},{"issue":"5","key":"10.1016\/j.intimp.2024.112446_b0790","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3109\/10428194.2014.953155","article-title":"<i>PRDM1<\/i>\/BLIMP1: a tumor suppressor gene in B and T cell lymphomas","volume":"56","author":"Boi","year":"2015","journal-title":"Leuk. Lymphoma"},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0795","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41392-021-00725-x","article-title":"AIM2 deficiency in B cells ameliorates systemic lupus erythematosus by regulating Blimp-1-Bcl-6 axis-mediated B-cell differentiation","volume":"6","author":"Yang","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.intimp.2024.112446_b0800","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2023.109710","article-title":"Overexpressed CD44 is associated with B-cell activation via the HA-CD44-AIM2 pathway in lupus B cells","volume":"255","author":"Yi","year":"2023","journal-title":"Clin. Immunol."},{"issue":"21","key":"10.1016\/j.intimp.2024.112446_b0805","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1038\/sj.onc.1203551","article-title":"Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors","volume":"19","author":"Hirano","year":"2000","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0810","doi-asserted-by":"crossref","first-page":"e781","DOI":"10.1002\/ctm2.781","article-title":"The IL-21-TET2-AIM2-c-MAF pathway drives the T follicular helper cell response in lupus-like disease","volume":"12","author":"Wu","year":"2022","journal-title":"Clin. Transl. Med."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0815","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/nrm2293","article-title":"Concepts in sumoylation: a decade on","volume":"8","author":"Geiss-Friedlander","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112446_b0820","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1002\/art.41677","article-title":"Aim2 couples with Ube2i for sumoylation-mediated repression of interferon signatures in systemic lupus erythematosus","volume":"73","author":"Lu","year":"2021","journal-title":"Arthritis Rheumatol."},{"issue":"82","key":"10.1016\/j.intimp.2024.112446_b0825","doi-asserted-by":"crossref","first-page":"82ra38","DOI":"10.1126\/scitranslmed.3002001","article-title":"Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions","volume":"3","author":"Dombrowski","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.intimp.2024.112446_b0830","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.03.008","article-title":"Interferon (IFN)-inducible absent in melanoma 2 proteins in the negative regulation of the type I IFN response: implications for lupus nephritis","volume":"132","author":"Choubey","year":"2020","journal-title":"Cytokine"},{"issue":"3","key":"10.1016\/j.intimp.2024.112446_b0835","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.immuni.2018.07.006","article-title":"Gasdermin D restrains type I interferon response to cytosolic DNA by disrupting ionic homeostasis","volume":"49","author":"Banerjee","year":"2018","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0840","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1006\/bbrc.1995.2269","article-title":"The interferon-inducible autoantigen, IFI 16: localization to the nucleolus and identification of a DNA-binding domain","volume":"214","author":"Dawson","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0845","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imlet.2010.06.008","article-title":"Systemic lupus erythematosus and increased risk to develop B cell malignancies: role of the p200-family proteins","volume":"133","author":"Veeranki","year":"2010","journal-title":"Immunol. Lett."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0850","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s13075-023-03094-8","article-title":"Renal interferon-inducible protein 16 expression is associated with disease activity and prognosis in lupus nephritis","volume":"25","author":"Wang","year":"2023","journal-title":"Arthritis Res. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0855","doi-asserted-by":"crossref","first-page":"15485","DOI":"10.1038\/s41598-019-51998-w","article-title":"Nucleosomal dsDNA stimulates APOL1 expression in human cultured podocytes by activating the cGAS\/IFI16-STING signaling pathway","volume":"9","author":"Davis","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2024.112446_b0860","doi-asserted-by":"crossref","first-page":"14392","DOI":"10.1038\/ncomms14392","article-title":"IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes","volume":"8","author":"Almine","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2024.112446_b0865","doi-asserted-by":"crossref","first-page":"14391","DOI":"10.1038\/ncomms14391","article-title":"IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP","volume":"8","author":"Jonsson","year":"2017","journal-title":"Nat. Commun."},{"issue":"7","key":"10.1016\/j.intimp.2024.112446_b0870","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.4049\/jimmunol.1402764","article-title":"cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection","volume":"194","author":"Storek","year":"2015","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2024.112446_b0875","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1089\/jir.2014.0168","article-title":"The extracellular IFI16 protein propagates inflammation in endothelial cells via p38 MAPK and NF-kappaB p65 activation","volume":"35","author":"Bawadekar","year":"2015","journal-title":"J. Interferon Cytokine Res."},{"issue":"9","key":"10.1016\/j.intimp.2024.112446_b0880","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/intimm\/dxt015","article-title":"Expression of murine Unc93b1 is up-regulated by interferon and estrogen signaling: implications for sex bias in the development of autoimmunity","volume":"25","author":"Panchanathan","year":"2013","journal-title":"Int. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0885","doi-asserted-by":"crossref","first-page":"1241694","DOI":"10.3389\/fimmu.2023.1241694","article-title":"Z\u03b1 domain proteins mediate the immune response","volume":"14","author":"Zhong","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0890","series-title":"Biological DNA Sensor","first-page":"205","article-title":"Chapter 9 - Cancer Pathogenesis and DNA Sensing*\u25a0*Authors contributed equally","author":"Shen","year":"2014"},{"issue":"24","key":"10.1016\/j.intimp.2024.112446_b0895","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.21037\/atm-21-6193","article-title":"ZBP1 is a significant pyroptosis regulator for systemic lupus erythematosus","volume":"9","author":"Huang","year":"2021","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.intimp.2024.112446_b0900","article-title":"Identification of diagnostic biomarkers in systemic lupus erythematosus based on bioinformatics analysis and machine learning","volume":"13","author":"Jiang","year":"2022","journal-title":"Front. Genet."},{"issue":"11","key":"10.1016\/j.intimp.2024.112446_b0905","doi-asserted-by":"crossref","first-page":"6465","DOI":"10.4049\/jimmunol.0904016","article-title":"Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization","volume":"184","author":"Zhang","year":"2010","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0910","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.4049\/jimmunol.1002315","article-title":"Macrophage differentiation and polarization via phosphatidylinositol 3-kinase\/Akt-ERK signaling pathway conferred by serum amyloid P component","volume":"187","author":"Zhang","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0915","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3389\/fcimb.2020.00238","article-title":"The PANoptosome: a deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis)","volume":"10","author":"Samir","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.intimp.2024.112446_b0920","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2023.109660","article-title":"Molecular characterization of PANoptosis-related genes with features of immune dysregulation in systemic lupus erythematosus","volume":"253","author":"Sun","year":"2023","journal-title":"Clin. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2024.112446_b0925","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21124402","article-title":"General and target-specific DExD\/H RNA helicases in eukaryotic translation initiation","volume":"21","author":"Shen","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.112446_b0930","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2021.198352","article-title":"DEAD-box RNA helicases: The driving forces behind RNA metabolism at the crossroad of viral replication and antiviral innate immunity","volume":"296","author":"Ali","year":"2021","journal-title":"Virus Res."},{"issue":"23","key":"10.1016\/j.intimp.2024.112446_b0935","doi-asserted-by":"crossref","first-page":"e113714","DOI":"10.15252\/embj.2023113714","article-title":"MICa\/b-dependent activation of natural killer cells by CD64(+) inflammatory type 2 dendritic cells contributes to autoimmunity","volume":"42","author":"S\u00e1nchez-Cerrillo","year":"2023","journal-title":"EMBO J."},{"key":"10.1016\/j.intimp.2024.112446_b0940","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.3389\/fimmu.2019.01880","article-title":"Epigenome-wide comparative study reveals key differences between mixed connective tissue disease and related systemic autoimmune diseases","volume":"10","author":"Carnero-Montoro","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112446_b0945","doi-asserted-by":"crossref","first-page":"8564650","DOI":"10.1155\/2023\/8564650","article-title":"Integrative bioinformatics analysis identifies DDX60 as a potential biomarker for systemic lupus erythematosus","volume":"2023","author":"Chen","year":"2023","journal-title":"Dis. Markers"},{"key":"10.1016\/j.intimp.2024.112446_b0950","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.virusres.2021.198658","article-title":"DEAD\/H-box helicases:anti-viral and pro-viral roles during infections","volume":"309","author":"Ullah","year":"2022","journal-title":"Virus Res."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0955","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13075-017-1501-z","article-title":"Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?","volume":"20","author":"Wahadat","year":"2018","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.intimp.2024.112446_b0960","doi-asserted-by":"crossref","first-page":"3567","DOI":"10.2147\/IJGM.S416493","article-title":"TRIM5 promotes systemic lupus erythematosus through CD4(+) T cells and macrophage","volume":"16","author":"Pan","year":"2023","journal-title":"Int J Gen Med."},{"issue":"1","key":"10.1016\/j.intimp.2024.112446_b0965","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/0886022X.2022.2027249","article-title":"Glomerular endothelial expression of type I IFN-stimulated gene, DExD\/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis","volume":"44","author":"Karasawa","year":"2022","journal-title":"Ren. Fail."},{"issue":"21","key":"10.1016\/j.intimp.2024.112446_b0970","doi-asserted-by":"crossref","DOI":"10.3390\/cells11213350","article-title":"A study on MDA5 signaling in splenic B cells from an imiquimod-induced lupus mouse model with proteomics","volume":"11","author":"Su","year":"2022","journal-title":"Cells."},{"key":"10.1016\/j.intimp.2024.112446_b0975","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fimmu.2019.01880","article-title":"Epigenome-wide comparative study reveals key differences between mixed connective tissue disease and related systemic autoimmune diseases","volume":"10","author":"Carnero-Montoro","year":"2019","journal-title":"Front. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2024.112446_b0980","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/ni.2091","article-title":"The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells","volume":"12","author":"Zhang","year":"2011","journal-title":"Nat. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112446_b0985","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1093\/rheumatology\/keac016","article-title":"Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjogren's syndrome","volume":"61","author":"Huijser","year":"2022","journal-title":"Rheumatology (Oxford)"},{"issue":"8","key":"10.1016\/j.intimp.2024.112446_b0990","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110856","article-title":"DDX41 is required for cGAS-STING activation against DNA virus infection","volume":"39","author":"Singh","year":"2022","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.intimp.2024.112446_b0995","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.4049\/jimmunol.1402066","article-title":"Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS","volume":"194","author":"Ma","year":"2015","journal-title":"J. Immunol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924009676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924009676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T15:36:58Z","timestamp":1720280218000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924009676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":198,"alternative-id":["S1567576924009676"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112446","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Decoding the connection between SLE and DNA Sensors: A comprehensive review","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112446","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112446"}}