{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:10:30Z","timestamp":1793398230198,"version":"4.5.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.intimp.2024.112611","type":"journal-article","created":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T02:47:07Z","timestamp":1720320427000},"page":"112611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["The complex association between the immune system and the skeletal system in osteoporosis: A study of single-cell RNA sequencing"],"prefix":"10.1016","volume":"138","author":[{"given":"Weiwei","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingbo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juzheng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6601-6086","authenticated-orcid":false,"given":"Xiangtao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2024.112611_b0005","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.54695","article-title":"Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment","volume":"9","author":"Zhong","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.intimp.2024.112611_b0010","doi-asserted-by":"crossref","unstructured":"Woodhead GA, Moss MM. Osteoporosis: diagnosis and prevention. Nurse Pract. 1998;23(11):18, 23-7, 31-2 passim; quiz 5-7.","DOI":"10.1097\/00006205-199811000-00004"},{"issue":"16","key":"10.1016\/j.intimp.2024.112611_b0015","doi-asserted-by":"crossref","first-page":"3697","DOI":"10.7150\/ijms.61080","article-title":"The Role of the Immune Microenvironment in Bone Regeneration","volume":"18","author":"Yang","year":"2021","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.intimp.2024.112611_b0020","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3389\/fimmu.2019.00797","article-title":"Experience in the Adaptive Immunity Impacts Bone Homeostasis, Remodeling, and Healing","volume":"10","author":"Bucher","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112611_b0025","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.abb.2014.06.003","article-title":"The immune system, bone and RANKL","volume":"561","author":"Guerrini","year":"2014","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.intimp.2024.112611_b0030","article-title":"T-Cell Mediated Inflammation in Postmenopausal Osteoporosis","volume":"12","author":"Wu","year":"2021","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112611_b0035","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.molmed.2016.06.002","article-title":"Osteoporosis: The Result of an 'Aged' Bone Microenvironment","volume":"22","author":"Yu","year":"2016","journal-title":"Trends Mol. Med."},{"issue":"1","key":"10.1016\/j.intimp.2024.112611_b0040","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s00774-018-0965-5","article-title":"Clinical immunity in bone and joints","volume":"37","author":"Tanaka","year":"2019","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.intimp.2024.112611_b0045","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.687037","article-title":"Immunoporosis: Role of Innate Immune Cells in Osteoporosis","volume":"12","author":"Saxena","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112611_b0050","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.666140","article-title":"Single-Cell RNA Sequencing Reveals B Cells Are Important Regulators in Fracture Healing","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Endocrinol. (Lausanne)."},{"issue":"19","key":"10.1016\/j.intimp.2024.112611_b0055","first-page":"e2100584","article-title":"N2-Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle","volume":"8","author":"Cai","year":"2021","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.intimp.2024.112611_b0060","first-page":"2485959","article-title":"Insights into the Role of Macrophage Polarization in the Pathogenesis of Osteoporosis","volume":"2022","author":"Wang","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"11","key":"10.1016\/j.intimp.2024.112611_b0065","first-page":"1044","article-title":"The role of red blood cells in immune response to infection: A review","volume":"38","author":"Zhang","year":"2022","journal-title":"Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi"},{"issue":"12","key":"10.1016\/j.intimp.2024.112611_b0070","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24129814","article-title":"Single-Cell RNA-Sequencing Reveals the Skeletal Cellular Dynamics in Bone Repair and Osteoporosis","volume":"24","author":"Wu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.112611_b0075","unstructured":"\u4e2d\u56fd\u5eb7\u590d\u533b\u5b66\u4f1a\u9aa8\u8d28\u758f\u677e\u9884\u9632\u4e0e\u5eb7\u590d\u4e13\u4e1a\u59d4\u5458\u4f1a. \u9aa8\u8d28\u758f\u677e\u6027\u690e\u4f53\u538b\u7f29\u9aa8\u6298\u8bca\u6cbb\u4e13\u5bb6\u5171\u8bc6(2021\u7248). \u4e2d\u534e\u533b\u5b66\u6742\u5fd7. 2021;101(41):9."},{"issue":"7","key":"10.1016\/j.intimp.2024.112611_b0080","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1007\/s11547-021-01353-9","article-title":"Utility of vertebral biopsy before vertebroplasty in patients with diagnosis of vertebral compression fracture","volume":"126","author":"Sozzi","year":"2021","journal-title":"Radiol. Med."},{"key":"10.1016\/j.intimp.2024.112611_b0085","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.actbio.2021.10.037","article-title":"Droplet microfluidics-based biomedical microcarriers","volume":"138","author":"Shao","year":"2022","journal-title":"Acta Biomater."},{"issue":"8","key":"10.1016\/j.intimp.2024.112611_b0090","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1093\/bioinformatics\/bts117","article-title":"BioQ: tracing experimental origins in public genomic databases using a novel data provenance model","volume":"28","author":"Saccone","year":"2012","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.intimp.2024.112611_b0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"issue":"7","key":"10.1016\/j.intimp.2024.112611_b0100","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"issue":"22","key":"10.1016\/j.intimp.2024.112611_b0105","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1093\/bioinformatics\/btab404","article-title":"Interfacing Seurat with the R tidy universe","volume":"37","author":"Mangiola","year":"2021","journal-title":"Bioinformatics"},{"key":"10.1016\/j.intimp.2024.112611_b0110","article-title":"Dimensionality reduction for visualizing single-cell data using UMAP","author":"Becht","year":"2018","journal-title":"Nat. Biotechnol."},{"issue":"5","key":"10.1016\/j.intimp.2024.112611_b0115","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"issue":"7745","key":"10.1016\/j.intimp.2024.112611_b0120","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/s41586-019-0969-x","article-title":"The single-cell transcriptional landscape of mammalian organogenesis","volume":"566","author":"Cao","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2024.112611_b0125","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/978-1-0716-1534-8_10","article-title":"Inference of Gene Regulatory Network from Single-Cell Transcriptomic Data Using pySCENIC","volume":"2328","author":"Kumar","year":"2021","journal-title":"Methods Mol. Biol."},{"issue":"18","key":"10.1016\/j.intimp.2024.112611_b0130","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1093\/bioinformatics\/btw313","article-title":"Complex heatmaps reveal patterns and correlations in multidimensional genomic data","volume":"32","author":"Gu","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.intimp.2024.112611_b0135","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/cells9092073","article-title":"Osteoblast-Osteoclast Communication and Bone Homeostasis","volume":"9","author":"Kim","year":"2020","journal-title":"Cells."},{"key":"10.1016\/j.intimp.2024.112611_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101608","article-title":"Osteocytes in bone aging: Advances, challenges, and future perspectives","volume":"77","author":"Cui","year":"2022","journal-title":"Ageing Res. Rev."},{"issue":"23","key":"10.1016\/j.intimp.2024.112611_b0145","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21239004","article-title":"A General Mechanism for Bone Development, Homeostasis, and Regeneration","volume":"21","author":"Damerau","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.intimp.2024.112611_b0150","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00418-018-1640-6","article-title":"Runx2, an inducer of osteoblast and chondrocyte differentiation","volume":"149","author":"Komori","year":"2018","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.intimp.2024.112611_b0155","doi-asserted-by":"crossref","first-page":"1091237","DOI":"10.3389\/fimmu.2023.1091237","article-title":"Single-cell RNA sequencing reveals the transcriptomic characteristics of peripheral blood mononuclear cells in hepatitis B vaccine non-responders","volume":"14","author":"Zhao","year":"2023","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0160","doi-asserted-by":"crossref","DOI":"10.3892\/ijmm.2023.5228","article-title":"Exhaustion-like dysfunction of T and NKT cells in an X-linked severe combined immunodeficiency patient with maternal engraftment by single-cell analysis","volume":"51","author":"Dong","year":"2023","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.intimp.2024.112611_b0165","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.3389\/fimmu.2018.02692","article-title":"Defining Memory CD8 T Cell","volume":"9","author":"Martin","year":"2018","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.112611_b0170","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.immuni.2018.03.015","article-title":"KLRG1(+) Effector CD8(+) T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity","volume":"48","author":"Herndler-Brandstetter","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2024.112611_b0175","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3389\/fimmu.2020.00611","article-title":"Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood","volume":"11","author":"Motwani","year":"2020","journal-title":"Front. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2024.112611_b0180","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/s41419-020-03046-z","article-title":"PERK controls bone homeostasis through the regulation of osteoclast differentiation and function","volume":"11","author":"Guo","year":"2020","journal-title":"Cell Death Dis."},{"issue":"12","key":"10.1016\/j.intimp.2024.112611_b0185","first-page":"3962","article-title":"Exosomes derived from bone marrow mesenchymal stem cells improve osteoporosis through promoting osteoblast proliferation via MAPK pathway","volume":"22","author":"Zhao","year":"2018","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0190","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jaci.2023.05.017","article-title":"TCF3 haploinsufficiency defined by immune, clinical, gene-dosage, and murine studies","volume":"152","author":"Boast","year":"2023","journal-title":"J. Allergy Clin. Immunol."},{"issue":"16","key":"10.1016\/j.intimp.2024.112611_b0195","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1242\/dev.106989","article-title":"Tcf3 expression marks both stem and progenitor cells in multiple epithelia","volume":"141","author":"Howard","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.intimp.2024.112611_b0200","doi-asserted-by":"crossref","first-page":"236","DOI":"10.3389\/fendo.2019.00236","article-title":"Updates on Osteoimmunology: What's New on the Cross-Talk Between Bone and Immune System","volume":"10","author":"Ponzetti","year":"2019","journal-title":"Front. Endocrinol. (Lausanne)."},{"issue":"12","key":"10.1016\/j.intimp.2024.112611_b0205","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1002\/cbin.11690","article-title":"M1 macrophage-derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA-98\/DUSP1\/JNK axis","volume":"45","author":"Yu","year":"2021","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.intimp.2024.112611_b0210","doi-asserted-by":"crossref","first-page":"1112363","DOI":"10.3389\/fendo.2023.1112363","article-title":"The impact of oxidative stress-induced mitochondrial dysfunction on diabetic microvascular complications","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Endocrinol. (Lausanne)."},{"issue":"12","key":"10.1016\/j.intimp.2024.112611_b0215","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1302\/2046-3758.612.BJR-2017-0102.R1","article-title":"Identification of potential pathogenic genes associated with osteoporosis","volume":"6","author":"Xia","year":"2017","journal-title":"Bone Joint Res."},{"key":"10.1016\/j.intimp.2024.112611_b0220","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.molimm.2022.11.008","article-title":"An update on the role of tumor necrosis factor alpha stimulating gene-6 in inflammatory diseases","volume":"152","author":"Li","year":"2022","journal-title":"Mol. Immunol."},{"issue":"38","key":"10.1016\/j.intimp.2024.112611_b0225","doi-asserted-by":"crossref","first-page":"25952","DOI":"10.1074\/jbc.M802138200","article-title":"TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation","volume":"283","author":"Mahoney","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0230","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1042\/BJ20060027","article-title":"Tumour necrosis factor alpha-stimulated gene-6 inhibits osteoblastic differentiation of human mesenchymal stem cells induced by osteogenic differentiation medium and BMP-2","volume":"398","author":"Tsukahara","year":"2006","journal-title":"Biochem. J"},{"key":"10.1016\/j.intimp.2024.112611_b0235","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.959417","article-title":"The immune factors have complex causal regulation effects on bone mineral density","volume":"13","author":"Cao","year":"2022","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.intimp.2024.112611_b0240","doi-asserted-by":"crossref","first-page":"5799","DOI":"10.1007\/s12035-019-1487-4","article-title":"Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death","volume":"56","author":"Jakaria","year":"2019","journal-title":"Mol. Neurobiol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0245","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1002\/jcb.20990","article-title":"Regulation of osteoblast differentiation by Nurr1 in MC3T3-E1 cell line and mouse calvarial osteoblasts","volume":"99","author":"Lee","year":"2006","journal-title":"J. Cell. Biochem."},{"issue":"6","key":"10.1016\/j.intimp.2024.112611_b0250","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1210\/me.2003-0247","article-title":"Regulation of the osteopontin gene by the orphan nuclear receptor NURR1 in osteoblasts","volume":"18","author":"Lammi","year":"2004","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.intimp.2024.112611_b0255","doi-asserted-by":"crossref","first-page":"657","DOI":"10.3389\/fimmu.2018.00657","article-title":"Immunoporosis: Immunology of Osteoporosis-Role of T Cells","volume":"9","author":"Srivastava","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112611_b0260","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.exphem.2021.12.191","article-title":"Recent advances in T-cell lymphoid neoplasms","volume":"106","author":"Bigas","year":"2022","journal-title":"Exp. Hematol."},{"issue":"24","key":"10.1016\/j.intimp.2024.112611_b0265","doi-asserted-by":"crossref","DOI":"10.3390\/cells12242854","article-title":"Natural Killer T (NKT) Cells in Autoimmune Hepatitis: Current Evidence from Basic and Clinical Research","volume":"12","author":"Poddighe","year":"2023","journal-title":"Cells."},{"key":"10.1016\/j.intimp.2024.112611_b0270","doi-asserted-by":"crossref","first-page":"1365843","DOI":"10.3389\/fimmu.2024.1365843","article-title":"Contribution of NKT cells and CD1d-expressing cells in obesity-associated adipose tissue inflammation","volume":"15","author":"Satoh","year":"2024","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2024.112611_b0275","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/s41419-018-0562-5","article-title":"CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis","volume":"9","author":"Lee","year":"2018","journal-title":"Cell Death Dis."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0280","doi-asserted-by":"crossref","first-page":"e0282424","DOI":"10.1371\/journal.pone.0282424","article-title":"Elevated levels of several chemokines in the cerebrospinal fluid of patients with subarachnoid hemorrhage are associated with worse clinical outcome","volume":"18","author":"Vlachogiannis","year":"2023","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.intimp.2024.112611_b0285","first-page":"831","article-title":"Simultaneous evaluation of the circulating levels of both Th1 and Th2 chemokines in patients with autoimmune Addison's disease","volume":"34","author":"Bellastella","year":"2011","journal-title":"J. Endocrinol. Invest."},{"key":"10.1016\/j.intimp.2024.112611_b0290","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.651049","article-title":"IgA Immune Complexes Induce Osteoclast-Mediated Bone Resorption","volume":"12","author":"Breedveld","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112611_b0295","doi-asserted-by":"crossref","first-page":"32188","DOI":"10.1038\/srep32188","article-title":"Effects of IL-1beta, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity","volume":"6","author":"Bester","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2024.112611_b0300","doi-asserted-by":"crossref","first-page":"1118886","DOI":"10.3389\/fendo.2023.1118886","article-title":"Identification of key immune genes of osteoporosis based on bioinformatics and machine learning","volume":"14","author":"Hao","year":"2023","journal-title":"Front. Endocrinol. (Lausanne)."},{"key":"10.1016\/j.intimp.2024.112611_b0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/cells11010132","article-title":"Regulation of TNF-Induced Osteoclast Differentiation","volume":"11","author":"Yao","year":"2021","journal-title":"Cells."},{"issue":"68\u201382","key":"10.1016\/j.intimp.2024.112611_b0310","first-page":"e5","article-title":"MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells","volume":"88","author":"Bottardi","year":"2020","journal-title":"Exp. Hematol."},{"issue":"2","key":"10.1016\/j.intimp.2024.112611_b0315","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/jcb.20435","article-title":"Variable expression of human myeloid specific nuclear antigen MNDA in monocyte lineage cells in atherosclerosis","volume":"95","author":"Briggs","year":"2005","journal-title":"J. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.intimp.2024.112611_b0320","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/biof.67","article-title":"Functional role of KLF10 in multiple disease processes","volume":"36","author":"Subramaniam","year":"2010","journal-title":"Biofactors"},{"issue":"16","key":"10.1016\/j.intimp.2024.112611_b0325","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1182\/blood.2021011044","article-title":"Molecular and cellular mechanisms that regulate human erythropoiesis","volume":"139","author":"Caulier","year":"2022","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.intimp.2024.112611_b0330","doi-asserted-by":"crossref","first-page":"217","DOI":"10.59566\/IJBS.2007.3217","article-title":"Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodeling","volume":"3","author":"Wang","year":"2007","journal-title":"Int. J. Biomed. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0335","doi-asserted-by":"crossref","first-page":"737","DOI":"10.3892\/ijmm.2016.2690","article-title":"Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of alpha5beta1 integrin expression","volume":"38","author":"Wang","year":"2016","journal-title":"Int. J. Mol. Med."},{"issue":"6","key":"10.1016\/j.intimp.2024.112611_b0340","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.cmet.2016.08.017","article-title":"A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation","volume":"24","author":"Arroyo","year":"2016","journal-title":"Cell Metab."},{"issue":"3","key":"10.1016\/j.intimp.2024.112611_b0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2024.109172","article-title":"Disruption of Mitochondrial Energy Metabolism Is a Putative Pathogenesis of Diamond-Blackfan Anemia","volume":"27","author":"Xiao","year":"2024","journal-title":"Iscience"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924011329?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924011329?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T17:35:22Z","timestamp":1722360922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924011329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":69,"alternative-id":["S1567576924011329"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112611","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The complex association between the immune system and the skeletal system in osteoporosis: A study of single-cell RNA sequencing","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112611"}}