{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:46:26Z","timestamp":1789577186454,"version":"build-2803163510"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.intimp.2024.112634","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T13:35:06Z","timestamp":1720272906000},"page":"112634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Patchouli alcohol alleviates metabolic dysfunction-associated steatohepatitis via inhibiting mitochondria-associated endoplasmic reticulum membrane disruption-induced hepatic steatosis and inflammation in rats"],"prefix":"10.1016","volume":"138","author":[{"given":"Xingyu","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyi","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijuan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yucui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiannan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziren","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuting","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8070-6369","authenticated-orcid":false,"given":"Yuhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.intimp.2024.112634_b0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41575-018-0009-6","article-title":"Triggering and resolution of inflammation in NASH","volume":"15","author":"Schuster","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.intimp.2024.112634_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110152","article-title":"Leucine aminopeptidase 3:a promising serum biomarker candidate for nonalcoholic steatohepatitis diagnosis","volume":"119","author":"Feng","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0015","article-title":"Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver\/steatohepatitis (NAFL\/NASH)","volume":"7","author":"Xu","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.intimp.2024.112634_b0020","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.2147\/DDDT.S315724","article-title":"Non-Alcoholic Steatohepatitis (NASH) \u2013 A Review of a Crowded Clinical Landscape","volume":"15","author":"Fraile","year":"2021","journal-title":"Driven by a Complex Disease, Drug Design, Development and Therapy"},{"issue":"2","key":"10.1016\/j.intimp.2024.112634_b0025","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.jhep.2017.11.012","article-title":"Determinants of fibrosis progression and regression in NASH","volume":"68","author":"Schuppan","year":"2018","journal-title":"J. Hepatol."},{"issue":"49","key":"10.1016\/j.intimp.2024.112634_b0030","doi-asserted-by":"crossref","first-page":"107703","DOI":"10.1007\/s11356-023-29702-3","article-title":"Filamin A facilitates NLRP3 inflammasome activation during arsenic-induced nonalcoholic steatohepatitis","volume":"30","author":"Yan","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"12","key":"10.1016\/j.intimp.2024.112634_b0035","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1001\/jama.2020.2298","article-title":"Nonalcoholic Steatohepatitis: A Review","volume":"323","author":"Sheka","year":"2020","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.intimp.2024.112634_b0040","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jhep.2010.06.044","article-title":"Effects of a high-fat diet on energy metabolism and ROS production in rat liver","volume":"54","author":"Vial","year":"2010","journal-title":"J. Hepatol."},{"issue":"5695","key":"10.1016\/j.intimp.2024.112634_b0045","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1126\/science.1103160","article-title":"Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes","volume":"306","author":"\u00d6zcan","year":"2004","journal-title":"Science"},{"issue":"7348","key":"10.1016\/j.intimp.2024.112634_b0050","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1038\/nature09968","article-title":"Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity","volume":"473","author":"Fu","year":"2011","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0055","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-19668-y","article-title":"AdipoR1\/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis","volume":"11","author":"Xu","year":"2020","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.intimp.2024.112634_b0060","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/nrm3440","article-title":"Endoplasmic reticulum\u2013mitochondria contacts: function of the junction","volume":"13","author":"Rowland","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0065","first-page":"31","article-title":"Traditional Uses, Phytochemistry, Pharmacology, Quality Control, Industrial Application, Pharmacokinetics and Network Pharmacology of Pogostemon cablin: A Comprehensive Review, The American journal of","volume":"50","author":"Fangfang","year":"2022","journal-title":"Chin. Med."},{"issue":"43","key":"10.1016\/j.intimp.2024.112634_b0070","doi-asserted-by":"crossref","first-page":"24399","DOI":"10.1039\/C8RA02422G","article-title":"Patchouli oil isolated from the leaves of Pogostemon cablin ameliorates ethanol-induced acute liver injury in rats via inhibition of oxidative stress and lipid accumulation","volume":"8","author":"Hui","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.intimp.2024.112634_b0075","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.3389\/fphar.2019.01134","article-title":"Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats","volume":"10","author":"Xue","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2024.112634_b0080","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.3389\/fphar.2019.01134","article-title":"Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats","volume":"10","author":"Wu","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.intimp.2024.112634_b0085","article-title":"Patchouli Alcohol Improves the Integrity of the Blood-Spinal Cord Barrier by Inhibiting Endoplasmic Reticulum Stress Through the Akt\/CHOP\/Caspase-3 Pathway Following Spinal Cord Injury","volume":"9","author":"Huang","year":"2021","journal-title":"Front Cell Dev Biol"},{"issue":"43","key":"10.1016\/j.intimp.2024.112634_b0090","doi-asserted-by":"crossref","first-page":"24399","DOI":"10.1039\/C8RA02422G","article-title":"Patchouli oil isolated from the leaves of Pogostemon cablin ameliorates ethanol-induced acute liver injury in rats via inhibition of oxidative stress and lipid accumulation","volume":"8","author":"Huang","year":"2018","journal-title":"RSC Adv"},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0095","doi-asserted-by":"crossref","first-page":"359","DOI":"10.4314\/tjpr.v13i3.7","article-title":"Isolation of (-)-Patchouli Alcohol from Patchouli Oil by Fractional Distillation and Crystallization","volume":"13","author":"Qing","year":"2014","journal-title":"Tropical Journal of Pharmaceutical Research"},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0100","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/hep.29367","article-title":"The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases","volume":"67","author":"Chalasani","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.intimp.2024.112634_b0105","doi-asserted-by":"crossref","first-page":"4850612","DOI":"10.1155\/2017\/4850612","article-title":"Availability, Pharmaceutics, Security, Pharmacokinetics, and Pharmacological Activities of Patchouli Alcohol","volume":"2017","author":"Hu","year":"2017","journal-title":"Evid Based Complement Alternat Med"},{"issue":"28","key":"10.1016\/j.intimp.2024.112634_b0110","doi-asserted-by":"crossref","first-page":"9330","DOI":"10.3748\/wjg.v20.i28.9330","article-title":"Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations","volume":"20","author":"Milic","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"4","key":"10.1016\/j.intimp.2024.112634_b0115","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0016-5085(98)70599-2","article-title":"Steatohepatitis: a tale of two \u201chits\u201d?","volume":"114","author":"Day","year":"1998","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.intimp.2024.112634_b0120","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jnutbio.2013.10.013","article-title":"Sesame oil mitigates nutritional steatohepatitis via attenuation of oxidative stress and inflammation: a tale of two-hit hypothesis","volume":"25","author":"Periasamy","year":"2014","journal-title":"The Journal of Nutritional Biochemistry"},{"issue":"8","key":"10.1016\/j.intimp.2024.112634_b0125","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.metabol.2015.12.012","article-title":"The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)","volume":"65","author":"Buzzetti","year":"2016","journal-title":"Metabolism"},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0130","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jhep.2014.10.039","article-title":"Molecular mechanism of PPAR\u03b1 action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease","volume":"62","author":"Pawlak","year":"2015","journal-title":"J Hepatol"},{"issue":"11","key":"10.1016\/j.intimp.2024.112634_b0135","doi-asserted-by":"crossref","DOI":"10.1172\/JCI151895","article-title":"Inhibiting SCAP\/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis","volume":"132","author":"Kawamura","year":"2022","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2024.112634_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108065","article-title":"Rotundic acid ameliorates non-alcoholic steatohepatitis via SREBP-1c\/ SCD1 signaling pathway and modulating gut microbiota","volume":"99","author":"Liu","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"20","key":"10.1016\/j.intimp.2024.112634_b0145","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1042\/BCJ20210071","article-title":"SREBP-1c and lipogenesis in the liver: an update","volume":"478","author":"Ferr\u00e9","year":"2021","journal-title":"Biochem. J"},{"issue":"7564","key":"10.1016\/j.intimp.2024.112634_b0150","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nature14557","article-title":"The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1","volume":"524","author":"Han","year":"2015","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0155","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1556\/2060.2020.00001","article-title":"Betanin effect on PPAR-alpha and SREBP-1c expression in NMRI mice model of steatohepatitis with fibrosis","volume":"107","author":"Yahaghi","year":"2020","journal-title":"Physiol Int"},{"key":"10.1016\/j.intimp.2024.112634_b0160","doi-asserted-by":"crossref","unstructured":"a.o.I. Medicine, U.o.C. Therapeutics, M. Pharmacology, U.o.P.a.f.u.i.r. Toxicology, The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis, Eur. J. Histochem.: EJH 64(4) (2020).","DOI":"10.4081\/ejh.2020.3175"},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0165","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.intimp.2014.06.032","article-title":"Involvement of hepatic peroxisome proliferator-activated receptor \u03b1\/\u03b3 in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats","volume":"22","author":"Zhao","year":"2014","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0170","doi-asserted-by":"crossref","DOI":"10.1038\/s43856-024-00465-3","article-title":"Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human","volume":"4","author":"Tsouka","year":"2024","journal-title":"Communications Medicine"},{"issue":"11","key":"10.1016\/j.intimp.2024.112634_b0175","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1007\/s11427-019-1563-3","article-title":"Regulation of glucose and lipid metabolism in health and disease","volume":"62","author":"Chen","year":"2019","journal-title":"Science China(life Sciences)"},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0180","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1053\/j.gastro.2018.06.083","article-title":"Mitochondrial Dysfunction and Signaling in Chronic Liver Diseases","volume":"155","author":"Mansouri","year":"2018","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.intimp.2024.112634_b0185","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12944-020-01210-0","article-title":"Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease","volume":"19","author":"Wang","year":"2020","journal-title":"Lipids Health Dis."},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0190","doi-asserted-by":"crossref","DOI":"10.3390\/cells9030695","article-title":"ER Stress Responses: An Emerging Modulator for Innate Immunity","volume":"9","author":"Di Conza","year":"2020","journal-title":"Cells"},{"issue":"10","key":"10.1016\/j.intimp.2024.112634_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2020.165838","article-title":"Mitochondrial dysfunction in metabolic syndrome","volume":"1866","author":"Prasun","year":"2020","journal-title":"Biochimica Et Biophysica Acta. Molecular Basis of Disease"},{"issue":"4","key":"10.1016\/j.intimp.2024.112634_b0200","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/CIRCRESAHA.119.315252","article-title":"Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction","volume":"126","author":"Hu","year":"2020","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.intimp.2024.112634_b0205","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1073\/pnas.91.4.1309","article-title":"Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis","volume":"91","author":"Virbasius","year":"1994","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2024.112634_b0210","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.freeradbiomed.2020.02.025","article-title":"Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease","volume":"152","author":"Chen","year":"2020","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.intimp.2024.112634_b0215","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1007\/s00125-020-05103-w","article-title":"Akap1 deficiency exacerbates diabetic cardiomyopathy in mice by NDUFS1-mediated mitochondrial dysfunction and apoptosis","volume":"63","author":"Qi","year":"2020","journal-title":"Diabetologia"},{"issue":"15","key":"10.1016\/j.intimp.2024.112634_b0220","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23158348","article-title":"Endoplasmic Reticulum and Mitochondria Contacts Correlate with the Presence and Severity of NASH in Humans","volume":"23","author":"Jin","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.112634_b0225","doi-asserted-by":"crossref","unstructured":"J.Y. Zhou, M.K. Sarkar, K. Okamura, J.E. Harris, J.E. Gudjonsson, K.A. Fitzgerald, Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT), Proceedings of the National Academy of Sciences of the United States of America 120(5) (2023) e2213777120.","DOI":"10.1073\/pnas.2213777120"},{"key":"10.1016\/j.intimp.2024.112634_b0230","article-title":"STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress","volume":"125","author":"Zhang","year":"2020","journal-title":"Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie"},{"issue":"10","key":"10.1016\/j.intimp.2024.112634_b0235","article-title":"The STING in Non-Alcoholic Fatty Liver Diseases: Potential Therapeutic Targets in Inflammation-Carcinogenesis Pathway, Pharmaceuticals (Basel","volume":"15","author":"Lv","year":"2022","journal-title":"Switzerland)"},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0240","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/JLB.3MR0720-513R","article-title":"NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma","volume":"108","author":"McKee","year":"2020","journal-title":"J. Leukoc. Biol."},{"issue":"3","key":"10.1016\/j.intimp.2024.112634_b0245","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.toxlet.2012.06.002","article-title":"Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice","volume":"212","author":"Zhang","year":"2012","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.intimp.2024.112634_b0250","article-title":"STING, the Endoplasmic Reticulum, and Mitochondria: Is Three a Crowd or a Conversation?","volume":"11","author":"Smith","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2024.112634_b0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2023.115938","article-title":"The critical roles of STING in mitochondrial homeostasis","volume":"220","author":"Zou","year":"2024","journal-title":"Biochem Pharmacol"},{"issue":"10","key":"10.1016\/j.intimp.2024.112634_b0260","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.2337\/db13-1751","article-title":"Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance","volume":"63","author":"Emily","year":"2014","journal-title":"Diabetes"},{"issue":"553","key":"10.1016\/j.intimp.2024.112634_b0265","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aaq1380","article-title":"ER-mitochondria cross-talk is regulated by the Ca(2+) sensor NCS1 and is impaired in Wolfram syndrome","volume":"11","author":"Angebault","year":"2018","journal-title":"Sci. Signal."},{"key":"10.1016\/j.intimp.2024.112634_b0270","unstructured":"H.-A.M. Isabel, S. David, V. Sara, I. Sa\u0161ka, B. Paola, K. Pamela, P. Natalia, V.S. R., H. Vanessa, V. Nuno, P. Gopal, A. Anna, J. Mariona, P. Reinald, G.-A. Isabel, C. Enrique, C. Noem\u00ed, C. Rui, Z. Antonio, Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease, Cell 177(4) (2019) 881-895.e17."},{"issue":"8","key":"10.1016\/j.intimp.2024.112634_b0275","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.medcli.2022.06.017","article-title":"Non-alcoholic steatohepatitis","volume":"159","author":"Romero-G\u00f3mez","year":"2022","journal-title":"Med. Clin."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692401155X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692401155X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T15:27:14Z","timestamp":1732375634000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156757692401155X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":55,"alternative-id":["S156757692401155X"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112634","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patchouli alcohol alleviates metabolic dysfunction-associated steatohepatitis via inhibiting mitochondria-associated endoplasmic reticulum membrane disruption-induced hepatic steatosis and inflammation in rats","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.112634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112634"}}