{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:57:35Z","timestamp":1790737055067,"version":"4.1.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.intimp.2024.113014","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T21:09:42Z","timestamp":1724706582000},"page":"113014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Polysaccharide of Atractylodes macrocephala Koidz alleviates NAFLD-induced hepatic inflammation in mice by modulating the TLR4\/MyD88\/NF-\u03baB pathway"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4895-1755","authenticated-orcid":false,"given":"Junyi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuzhan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanxia","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinliang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danning","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1039-9902","authenticated-orcid":false,"given":"Nan","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.intimp.2024.113014_b0005","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.3390\/nu15061490","article-title":"Natural product skatole ameliorates lipotoxicity-induced multiple hepatic damage under hyperlipidemic conditions in hepatocytes","volume":"15","author":"Hong","year":"2023","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0010","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/joim.13531","article-title":"Current treatment of non-alcoholic fatty liver disease","volume":"292","author":"Paternostro","year":"2022","journal-title":"J. Intern. Med."},{"issue":"24","key":"10.1016\/j.intimp.2024.113014_b0015","doi-asserted-by":"crossref","first-page":"15489","DOI":"10.3390\/ijms232415489","article-title":"Non-alcoholic fatty liver disease (NAFLD) pathogenesis and natural products for prevention and treatment","volume":"23","author":"Guo","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0020","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s10020-019-0085-2","article-title":"miR-122 promotes hepatic lipogenesis via inhibiting the LKB1\/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease","volume":"25","author":"Long","year":"2019","journal-title":"Mol. Med."},{"key":"10.1016\/j.intimp.2024.113014_b0025","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jare.2022.08.006","article-title":"ANGPTL8 accelerates liver fibrosis mediated by HFD-induced inflammatory activity via LILRB2\/ERK signaling pathways","volume":"47","author":"Zhang","year":"2023","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.intimp.2024.113014_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101462","article-title":"Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-\u03baB signaling pathway","volume":"59","author":"Jiang","year":"2022","journal-title":"Mol. Metab."},{"key":"10.1016\/j.intimp.2024.113014_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2022.105137","article-title":"Plant sterol ester of \u03b1-linolenic acid improves NAFLD through modulating gut microbiota and attenuating lipopolysaccharide-induced inflammation via regulating TLR4\/NF-\u03baB signaling pathway","volume":"94","author":"Han","year":"2022","journal-title":"J. Funct. Foods"},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0040","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s43088-020-00078-4","article-title":"Molecular mechanisms and the vital roles of resistin, TLR 4, and NF-\u03baB in treating type 2 diabetic complications","volume":"9","author":"Gudise","year":"2020","journal-title":"Beni-Suef University J. Basic Appl. Sci."},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11020468","article-title":"Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: pathophysiological mechanisms and new therapeutic strategies","volume":"11","author":"Vetrano","year":"2023","journal-title":"Biomedicines"},{"issue":"10","key":"10.1016\/j.intimp.2024.113014_b0050","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/s41575-023-00807-x","article-title":"Hepatic inflammatory responses in liver fibrosis","volume":"20","author":"Hammerich","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0055","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4254\/wjh.v15.i2.180","article-title":"Antioxidant and anti-inflammatory agents in chronic liver diseases: Molecular mechanisms and therapy","volume":"15","author":"Zhang","year":"2023","journal-title":"World J. Hepatol."},{"key":"10.1016\/j.intimp.2024.113014_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2023.106925","article-title":"Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development","volume":"196","author":"Wang","year":"2023","journal-title":"Pharmacol. Res."},{"issue":"7","key":"10.1016\/j.intimp.2024.113014_b0065","doi-asserted-by":"crossref","first-page":"998","DOI":"10.3390\/antiox10070998","article-title":"Ethyl acetate fraction of amomum villosum var. xanthioides attenuates hepatic endoplasmic reticulum stress-induced non-alcoholic steatohepatitis via improvement of antioxidant capacities","volume":"10","author":"Cho","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.intimp.2024.113014_b0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/2209574","article-title":"PAMK relieves LPS-induced enteritis and improves intestinal flora disorder in goslings","volume":"2021","author":"Li","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"9","key":"10.1016\/j.intimp.2024.113014_b0075","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1089\/jmf.2018.4393","article-title":"Polysaccharide ofAtractylodes macrocephala Koidz enhances cytokine secretion by stimulating theTLR4\u2013MyD88\u2013NF-\u03baB signaling pathway in the mouse spleen","volume":"22","author":"Li","year":"2019","journal-title":"J. Med. Food"},{"key":"10.1016\/j.intimp.2024.113014_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2024.106201","article-title":"Identification of key genes involved in the alleviative effects of Polysaccharide of Atractylodes macrocephala Koidz on high-fat diet-induced nonalcoholic fatty liver disease in mice","volume":"116","author":"Chen","year":"2024","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.intimp.2024.113014_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107692","article-title":"Polysaccharide of Atractylodes macrocephala Koidz regulates LPS-mediated mouse hepatitis through the TLR4-MyD88-NF-\u03baB signaling pathway","volume":"98","author":"Guo","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0090","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.psj.2020.11.036","article-title":"Protective effect of the new prepared Atractylodes macrocephala Koidz polysaccharide on fatty liver hemorrhagic syndrome in laying hens","volume":"100","author":"Miao","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.intimp.2024.113014_b0095","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.ijbiomac.2019.06.059","article-title":"Polysaccharide extracted from Atractylodes macrocephala Koidz (PAMK) induce apoptosis in transplanted H22 cells in mice","volume":"137","author":"Feng","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.intimp.2024.113014_b0100","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ijbiomac.2020.06.003","article-title":"Immunomodulatory activity-guided isolation and characterization of a novel polysaccharide from Atractylodis macrocephalae Koidz","volume":"161","author":"Xue","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"21","key":"10.1016\/j.intimp.2024.113014_b0105","doi-asserted-by":"crossref","first-page":"R1147","DOI":"10.1016\/j.cub.2017.09.019","article-title":"The liver","volume":"27","author":"Trefts","year":"2017","journal-title":"Curr. Biol."},{"issue":"20","key":"10.1016\/j.intimp.2024.113014_b0110","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1042\/CS20190654","article-title":"The immune niche of the liver","volume":"135","author":"Cheng","year":"2021","journal-title":"Clin. Sci."},{"key":"10.1016\/j.intimp.2024.113014_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2020.109199","article-title":"High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms","volume":"330","author":"Lian","year":"2020","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.intimp.2024.113014_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2019.154015","article-title":"Curcumin analog CUR5\u20138 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity","volume":"103","author":"Lee","year":"2020","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41574-021-00584-0","article-title":"Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD","volume":"18","author":"Tamaki","year":"2022","journal-title":"Nat. Rev. Endocrinol."},{"issue":"4","key":"10.1016\/j.intimp.2024.113014_b0130","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1002\/hep.32475","article-title":"Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score","volume":"76","author":"Pai","year":"2022","journal-title":"Hepatology"},{"issue":"23","key":"10.1016\/j.intimp.2024.113014_b0135","doi-asserted-by":"crossref","first-page":"6020","DOI":"10.1039\/D3AN01432K","article-title":"Portable dual-channel blood enzyme analyzer for point-of-care liver function detection","volume":"148","author":"Sang","year":"2023","journal-title":"Analyst"},{"issue":"8","key":"10.1016\/j.intimp.2024.113014_b0140","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s00535-018-1451-5","article-title":"To die or not to die: death signaling in nonalcoholic fatty liver disease","volume":"53","author":"Akazawa","year":"2018","journal-title":"J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0145","doi-asserted-by":"crossref","first-page":"e202100675","DOI":"10.1002\/cbdv.202100675","article-title":"Effect of emodin on hyperlipidemia and hepatic lipid metabolism in zebrafish larvae fed a high-cholesterol diet**","volume":"19","author":"He","year":"2022","journal-title":"Chem. Biodivers."},{"issue":"5","key":"10.1016\/j.intimp.2024.113014_b0150","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1039\/C7FO00103G","article-title":"Sulfated polysaccharides from Enteromorpha prolifera suppress SREBP-2 and HMG-CoA reductase expression and attenuate non-alcoholic fatty liver disease induced by a high-fat diet","volume":"8","author":"Ren","year":"2017","journal-title":"Food Funct"},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0155","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00018-018-2947-0","article-title":"Molecular pathways of nonalcoholic fatty liver disease development and progression","volume":"76","author":"Bessone","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"issue":"4","key":"10.1016\/j.intimp.2024.113014_b0160","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.7150\/ijbs.68873","article-title":"Atractylenolide III ameliorates non-alcoholic fatty liver disease by activating hepatic adiponectin receptor 1-mediated AMPK pathway","volume":"18","author":"Li","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.intimp.2024.113014_b0165","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.767314","article-title":"Current and potential therapies targeting inflammation in NASH","volume":"12","author":"Albhaisi","year":"2021","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.intimp.2024.113014_b0170","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.880298","article-title":"Association of inflammatory cytokines with non-alcoholic fatty liver disease","volume":"13","author":"Duan","year":"2022","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2024.113014_b0175","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1039\/D0FO02736G","article-title":"Hesperetin ameliorates hepatic oxidative stress and inflammationvia the PI3K\/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD","volume":"12","author":"Li","year":"2021","journal-title":"Food Funct."},{"key":"10.1016\/j.intimp.2024.113014_b0180","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.827516","article-title":"Amelioration of non-alcoholic steatohepatitis by atractylodes macrocephala polysaccharide, chlorogenic acid, and geniposide combination is associated with reducing endotoxin gut leakage","volume":"12","author":"Leng","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.intimp.2024.113014_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2021.108602","article-title":"Tomatidine ameliorates obesity-induced nonalcoholic fatty liver disease in mice","volume":"91","author":"Wu","year":"2021","journal-title":"J. Nutr. Biochem."},{"issue":"2","key":"10.1016\/j.intimp.2024.113014_b0190","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4093\/dmj.2019.0042","article-title":"Combination of probiotics and salvia miltiorrhiza polysaccharide alleviates hepatic steatosis via gut microbiota modulation and insulin resistance improvement in high fat-induced NAFLD mice","volume":"44","author":"Wang","year":"2020","journal-title":"Diabetes Metab. J."},{"issue":"5","key":"10.1016\/j.intimp.2024.113014_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101725","article-title":"Lipopolysaccharide-induced splenic ferroptosis in goslings was alleviated by polysaccharide of atractylodes macrocephala koidz associated with proinflammatory factors","volume":"101","author":"Li","year":"2022","journal-title":"Poult. Sci."},{"issue":"4","key":"10.1016\/j.intimp.2024.113014_b0200","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.jhep.2022.06.012","article-title":"Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease \u2013 novel insights into cellular communication circuits","volume":"77","author":"Peiseler","year":"2022","journal-title":"J. Hepatol."},{"issue":"4","key":"10.1016\/j.intimp.2024.113014_b0205","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1007\/s00018-020-03656-y","article-title":"TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling","volume":"78","author":"Ciesielska","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0210","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12974-019-1538-9","article-title":"Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4\/NF-\u03baB pathway","volume":"16","author":"Zusso","year":"2019","journal-title":"J. Neuroinflammation"},{"issue":"23","key":"10.1016\/j.intimp.2024.113014_b0215","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.1111\/bph.15642","article-title":"Sphingolipid metabolism during Toll-like receptor 4 (TLR4)-mediated macrophage activation","volume":"178","author":"Olona","year":"2021","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.intimp.2024.113014_b0220","doi-asserted-by":"crossref","first-page":"11686","DOI":"10.1038\/ncomms11686","article-title":"Stepwise phosphorylation of p65 promotes NF-kappaB activation and NK cell responses during target cell recognition","volume":"7","author":"Kwon","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2024.113014_b0225","doi-asserted-by":"crossref","first-page":"407","DOI":"10.2147\/JIR.S140188","article-title":"Mechanisms of NF-kappaB p65 and strategies for therapeutic manipulation","volume":"11","author":"Giridharan","year":"2018","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.intimp.2024.113014_b0230","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.molimm.2019.09.020","article-title":"Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2\/ TLR4\/ NF-\u03baB pathways in BV2 cells","volume":"116","author":"Zhang","year":"2019","journal-title":"Mol. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2024.113014_b0235","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1139\/cjpp-2020-0305","article-title":"Involvement of Rho-kinase\/IkappaB-alpha\/NF-kappaB activation in IL-1beta-induced inflammatory response and oxidative stress in human chondrocytes","volume":"99","author":"Tiftik","year":"2021","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0240","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s41392-022-00925-z","article-title":"Signaling pathways and targeted therapy for myocardial infarction","volume":"7","author":"Zhang","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.intimp.2024.113014_b0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115999","article-title":"Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4\/NF-\u03baB\/NLRP3 pathway","volume":"303","author":"Yan","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2024.113014_b0250","article-title":"Pharmacological effects and molecular protective mechanisms of astragalus polysaccharides on nonalcoholic fatty liver disease","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2024.113014_b0255","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41584-018-0109-2","article-title":"Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis","volume":"15","author":"Chen","year":"2019","journal-title":"Nat. Rev. Rheumatol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924015352?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924015352?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T17:37:36Z","timestamp":1731087456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924015352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":51,"alternative-id":["S1567576924015352"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113014","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polysaccharide of Atractylodes macrocephala Koidz alleviates NAFLD-induced hepatic inflammation in mice by modulating the TLR4\/MyD88\/NF-\u03baB pathway","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113014"}}