{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:51:54Z","timestamp":1784674314952,"version":"3.55.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017520","name":"Chengdu Medical College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.intimp.2024.113117","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T21:55:41Z","timestamp":1726610141000},"page":"113117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"PB","title":["Artemisinin attenuates perinatal inflammation and consequent oxidative stress in oligodendrocyte precursor cells by inhibiting IRAK-4 and IRAK-1"],"prefix":"10.1016","volume":"142","author":[{"given":"Feng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixian","family":"Gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunchi","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yishi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengya","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4864-6586","authenticated-orcid":false,"given":"Hong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2024.113117_b0005","first-page":"S1","article-title":"Born too soon: preterm birth matters","volume":"1","author":"Howson","year":"2013","journal-title":"Reprod. Health Suppl."},{"key":"10.1016\/j.intimp.2024.113117_b0010","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1016\/S0140-6736(16)31593-8","article-title":"Global, regional, and national causes of under-5 mortality in 2000\u201315: an updated systematic analysis with implications for the Sustainable Development Goals","volume":"10063","author":"Liu","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2024.113117_b0015","article-title":"Cerebral regional tissue Oxygen Saturation to Guide Oxygen Delivery in preterm neonates during immediate transition after birth (COSGOD III): multicentre randomised phase 3 clinical trial","volume":"55","author":"Pichler","year":"2023","journal-title":"BMJ"},{"key":"10.1016\/j.intimp.2024.113117_b0020","article-title":"Perinatal inflammation influences but does not arrest rapid immune development in preterm babies","volume":"1","author":"Kamdar","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2024.113117_b0025","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1473-3099(14)70710-8","article-title":"Infection-induced inflammation and cerebral injury in preterm infants","volume":"8","author":"Strunk","year":"2014","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.intimp.2024.113117_b0030","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/s41390-021-01633-0","article-title":"Chorioamnionitis and neonatal outcomes","volume":"2","author":"Jain","year":"2022","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.intimp.2024.113117_b0035","article-title":"Anti-inflammatory therapies for treatment of inflammation-related preterm brain injury","volume":"8","author":"Prasad","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.113117_b0040","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.clp.2008.07.011","article-title":"Cytokines and perinatal brain damage","volume":"4","author":"Dammann","year":"2008","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.intimp.2024.113117_b0045","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.ijdevneu.2011.04.004","article-title":"The biological basis of injury and neuroprotection in the fetal and neonatal brain","volume":"6","author":"Rees","year":"2011","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.intimp.2024.113117_b0050","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ijdevneu.2018.01.001","article-title":"Neonatal systemic inflammation and the risk of low scores on measures of reading and mathematics achievement at age 10 years among children born extremely preterm","author":"Leviton","year":"2018","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.intimp.2024.113117_b0055","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1002\/med.21842","article-title":"The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases","volume":"6","author":"Efferth","year":"2021","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.intimp.2024.113117_b0060","article-title":"Evaluation of biological mechanisms of artemisinin on bovine mammary epithelial cells by integration of network pharmacology and TMT-based quantitative proteomics","author":"Tong","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2024.113117_b0065","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.freeradbiomed.2016.10.498","article-title":"ROS-JNK1\/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis","author":"Zhang","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2024.113117_b0070","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1093\/carcin\/bgv098","article-title":"Artesunate induces ROS- and p38 MAPK-mediated apoptosis and counteracts tumor growth in vivo in embryonal rhabdomyosarcoma cells","volume":"9","author":"Beccafico","year":"2015","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.intimp.2024.113117_b0075","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1862437","article-title":"Artemether activation of AMPK\/GSK3beta(ser9)\/Nrf2 signaling confers neuroprotection towards beta-amyloid-induced neurotoxicity in 3xTg Alzheimer's mouse model","author":"Li","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.intimp.2024.113117_b0080","article-title":"Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS\/TXNIP\/NLRP3\/Caspase-1 signaling pathway","author":"Wang","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.113117_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115972","article-title":"Artemisinin protects dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in a mouse model of Parkinson's disease","author":"Lim","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.113117_b0090","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1248\/bpb.b23-00326","article-title":"Osmundacetone Alleviates Cerebral Ischemia-Reperfusion Injury in Rats","volume":"11","author":"Li","year":"2023","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.intimp.2024.113117_b0095","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/s41401-021-00634-3","article-title":"Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia","volume":"7","author":"Lin","year":"2021","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.intimp.2024.113117_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105049","article-title":"Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem\/progenitor cells differentiation into NeuN(+) neurons","author":"Liu","year":"2020","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.intimp.2024.113117_b0105","doi-asserted-by":"crossref","first-page":"4718","DOI":"10.1007\/s12035-021-02710-5","article-title":"Neurogenesis and proliferation of neural stem\/progenitor cells conferred by artesunate via FOXO3a\/p27Kip1 axis in mouse stroke model","volume":"8","author":"Zhang","year":"2022","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.intimp.2024.113117_b0110","doi-asserted-by":"crossref","first-page":"W357","DOI":"10.1093\/nar\/gkz382","article-title":"SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules","volume":"1","author":"Daina","year":"2019","journal-title":"Nucleic. Acids. Res."},{"key":"10.1016\/j.intimp.2024.113117_b0115","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nature736","article-title":"Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4","volume":"6882","author":"Suzuki","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2024.113117_b0120","doi-asserted-by":"crossref","first-page":"5567","DOI":"10.1073\/pnas.082100399","article-title":"IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase","volume":"8","author":"Li","year":"2002","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2024.113117_b0125","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S1097-2765(03)00053-4","article-title":"Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members","volume":"2","author":"Janssens","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1016\/j.intimp.2024.113117_b0130","doi-asserted-by":"crossref","first-page":"732","DOI":"10.14336\/AD.2020.0523","article-title":"Deficiency of endothelial nitric oxide synthase (eNOS) exacerbates brain damage and cognitive deficit in A mouse model of vascular dementia","volume":"3","author":"An","year":"2021","journal-title":"Aging Dis."},{"key":"10.1016\/j.intimp.2024.113117_b0135","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/ana.20322","article-title":"Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain","volume":"1","author":"Felderhoff-Mueser","year":"2005","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.intimp.2024.113117_b0140","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.neuroscience.2011.08.059","article-title":"Interleukin-1 receptor associated kinases-1\/4 inhibition protects against acute hypoxia\/ischemia-induced neuronal injury in vivo and in vitro","author":"Yang","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.intimp.2024.113117_b0145","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neuroscience.2018.01.023","article-title":"Microglia and neonatal brain injury","author":"Mallard","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.intimp.2024.113117_b0150","doi-asserted-by":"crossref","first-page":"6223","DOI":"10.1021\/acs.jmedchem.9b00439","article-title":"Development of potent and selective pyrazolopyrimidine IRAK4 inhibitors","volume":"13","author":"Bryan","year":"2019","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.intimp.2024.113117_b0155","doi-asserted-by":"crossref","first-page":"13507","DOI":"10.1073\/pnas.1714386114","article-title":"Crystal structure of human IRAK1","volume":"51","author":"Wang","year":"2017","journal-title":"PNAS"},{"key":"10.1016\/j.intimp.2024.113117_b0160","doi-asserted-by":"crossref","first-page":"D439","DOI":"10.1093\/nar\/gkab1061","article-title":"AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models","volume":"1","author":"Varadi","year":"2022","journal-title":"Nucleic. Acids. Res."},{"key":"10.1016\/j.intimp.2024.113117_b0165","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"7873","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2024.113117_b0170","first-page":"84","article-title":"Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay","volume":"6141","author":"Martinez","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.intimp.2024.113117_b0175","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1038\/nprot.2014.138","article-title":"The cellular thermal shift assay for evaluating drug target interactions in cells","volume":"9","author":"Jafari","year":"2014","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.intimp.2024.113117_b0180","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/emboj.2013.2","article-title":"IRAK-M mediates Toll-like receptor\/IL-1R-induced NFkappaB activation and cytokine production","volume":"4","author":"Zhou","year":"2013","journal-title":"EMBO J."},{"key":"10.1016\/j.intimp.2024.113117_b0185","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/s41423-019-0286-1","article-title":"Correction to: The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1\u03b2 transcription and processing in monocytes","volume":"12","author":"Singh","year":"2019","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.intimp.2024.113117_b0190","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1523\/JNEUROSCI.3297-15.2016","article-title":"Hyaluronidase and hyaluronan oligosaccharides promote neurological recovery after intraventricular hemorrhage","volume":"3","author":"Vinukonda","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.intimp.2024.113117_b0195","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1038\/s41419-022-05483-4","article-title":"Epigenetic priming of immune\/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury","volume":"12","author":"Schang","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.intimp.2024.113117_b0200","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/bcpt.13848","article-title":"Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1-polarized microglia and suppressing inflammation through AMPK\/mTORC1\/GPX4 pathway","volume":"5","author":"Xie","year":"2023","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.intimp.2024.113117_b0205","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1248\/bpb.b20-00604","article-title":"Artesunate provides neuroprotection against cerebral ischemia-reperfusion injury via the TLR-4\/NF-kappaB pathway in rats","volume":"3","author":"Chen","year":"2021","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.intimp.2024.113117_b0210","article-title":"Artesunate attenuates inflammatory injury and inhibits the NF-kappaB pathway in a mouse model of cerebral ischemia","volume":"11","author":"Liu","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.intimp.2024.113117_b0215","first-page":"17","article-title":"Artesunate activates Nrf2 pathway-driven anti-inflammatory potential through ERK signaling in microglial BV2 cells","volume":"1","author":"Lee","year":"2012","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.intimp.2024.113117_b0220","article-title":"A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors","volume":"3","author":"Taubenschmid-Stowers","year":"2023","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.intimp.2024.113117_b0225","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.freeradbiomed.2016.05.023","article-title":"Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult","author":"Zheng","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2024.113117_b0230","article-title":"Artemisinin attenuated hydrogen peroxide (H(2)O(2))-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK pathway","volume":"11","author":"Zhao","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2024.113117_b0235","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/s41392-023-01666-3","article-title":"The tumor-enriched small molecule gambogic amide suppresses glioma by targeting WDR1-dependent cytoskeleton remodeling","volume":"1","author":"Qu","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.intimp.2024.113117_b0240","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/15548627.2023.2261758","article-title":"Artesunate Sensitizes human hepatocellular carcinoma to sorafenib via exacerbating AFAP1L2-SRC-FUNDC1 axis-dependent mitophagy","volume":"3","author":"Ma","year":"2024","journal-title":"Autophagy"},{"key":"10.1016\/j.intimp.2024.113117_b0245","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4049\/jimmunol.2100115","article-title":"TLR and IKK complex-mediated innate immune signaling inhibits stress granule assembly","volume":"1","author":"Samir","year":"2021","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.113117_b0250","doi-asserted-by":"crossref","first-page":"10071","DOI":"10.1021\/acs.jmedchem.7b01290","article-title":"Discovery and optimization of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) for the treatment of mutant MYD88(L265P) diffuse large B-cell lymphoma","volume":"24","author":"Scott","year":"2017","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.intimp.2024.113117_b0255","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1074\/jbc.RA119.011857","article-title":"A highly selective inhibitor of interleukin-1 receptor-associated kinases 1\/4 (IRAK-1\/4) delineates the distinct signaling roles of IRAK-1\/4 and the TAK1 kinase","volume":"6","author":"Scarneo","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2024.113117_b0260","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.chembiol.2017.07.011","article-title":"Takinib, a selective TAK1 inhibitor, broadens the therapeutic efficacy of TNF-alpha inhibition for cancer and autoimmune disease","volume":"8","author":"Totzke","year":"2017","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.intimp.2024.113117_b0265","doi-asserted-by":"crossref","first-page":"8627","DOI":"10.2147\/IJN.S220754","article-title":"Co-delivery of dihydroartemisinin and HMGB1 siRNA By TAT-modified cationic liposomes through the TLR4 signaling pathway for treatment of lupus nephritis","author":"Diao","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.intimp.2024.113117_b0270","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/2782429","article-title":"Artemisinin and its derivate alleviate pulmonary hypertension and vasoconstriction in rodent models","author":"Bao","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.intimp.2024.113117_b0275","article-title":"Artemisinin-derived artemisitene blocks ROS-mediated NLRP3 inflammasome and alleviates ulcerative colitis","volume":"Pt B","author":"Hua","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113117_b0280","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/cmi.2015.62","article-title":"The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1beta transcription and processing in monocytes","volume":"6","author":"Singh","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.intimp.2024.113117_b0285","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/4350965","article-title":"ROS and ROS-mediated cellular signaling","author":"Zhang","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.intimp.2024.113117_b0290","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/cr.2010.178","article-title":"Crosstalk of reactive oxygen species and NF-kappaB signaling","volume":"1","author":"Morgan","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.intimp.2024.113117_b0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2018.11.017","article-title":"NRF2 and NF-\u049bB interplay in cerebrovascular and neurodegenerative disorders: molecular mechanisms and possible therapeutic approaches","author":"Sivandzade","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2024.113117_b0300","first-page":"86","article-title":"The selectivity of artemisinin-based drugs on human lung normal and cancer cells","author":"Li","year":"2018","journal-title":"Environ. Toxicol. Pharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924016382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924016382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:56:08Z","timestamp":1734069368000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924016382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":60,"alternative-id":["S1567576924016382"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113117","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Artemisinin attenuates perinatal inflammation and consequent oxidative stress in oligodendrocyte precursor cells by inhibiting IRAK-4 and IRAK-1","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113117","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113117"}}