{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:42:55Z","timestamp":1793148175539,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.intimp.2024.113155","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T07:38:47Z","timestamp":1726213127000},"page":"113155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"PA","title":["Synergistic effect and mechanism of monoacylglycerol lipase inhibitor and Icaritin in the treatment of ulcerative colitis"],"prefix":"10.1016","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0307-9774","authenticated-orcid":false,"given":"Deyu","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingfei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongguang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingchun","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guimin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2024.113155_b0005","article-title":"Polysaccharides from natural resources exhibit great potential in the treatment of ulcerative colitis: a review","volume":"254","author":"Niu","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"33\u201334","key":"10.1016\/j.intimp.2024.113155_b0010","first-page":"564","article-title":"Ulcerative Colitis-Diagnostic and Therapeutic Algorithms","volume":"117","author":"Kucharzik","year":"2020","journal-title":"Deutsches Arzteblatt International."},{"key":"10.1016\/j.intimp.2024.113155_b0015","doi-asserted-by":"crossref","first-page":"e35020","DOI":"10.1097\/MD.0000000000035020","article-title":"Pathological mechanism and targeted drugs of ulcerative colitis: A review","volume":"102","author":"Guo","year":"2023","journal-title":"Medicine"},{"issue":"Suppl 1","key":"10.1016\/j.intimp.2024.113155_b0020","first-page":"59","article-title":"Mechanism of pathogenesis of inflammatory bowel diseases, Nihon rinsho","volume":"70","author":"Kanai","year":"2012","journal-title":"Japanese Journal of Clinical Medicine"},{"key":"10.1016\/j.intimp.2024.113155_b0025","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1080\/00365521.2019.1595708","article-title":"Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis","volume":"54","author":"Tan","year":"2019","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.intimp.2024.113155_b0030","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.tcb.2020.10.001","article-title":"Tight Junction Structure and Function Revisited","volume":"30","author":"Otani","year":"2020","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.intimp.2024.113155_b0035","doi-asserted-by":"crossref","first-page":"8397111","DOI":"10.1155\/2023\/8397111","article-title":"Mechanism of Jiawei Zhengqi Powder in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking","volume":"2023","author":"Zhao","year":"2023","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.intimp.2024.113155_b0040","doi-asserted-by":"crossref","first-page":"23193","DOI":"10.18632\/aging.203611","article-title":"Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK\/Nrf2\/NLRP3 inflammasome","volume":"13","author":"Zhang","year":"2021","journal-title":"Aging-Us."},{"key":"10.1016\/j.intimp.2024.113155_b0045","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1053\/j.gastro.2016.11.018","article-title":"Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-\u03baB, and Up-regulating Expression of MicroRNA-21","volume":"152","author":"Yang","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2024.113155_b0050","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1053\/j.gastro.2020.03.087","article-title":"Role of Cannabis and Its Derivatives in Gastrointestinal and Hepatic Disease","volume":"159","author":"Gotfried","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2024.113155_b0055","first-page":"451","article-title":"Role of endogenous cannabinoid system in the gut","volume":"65","author":"Lin","year":"2013","journal-title":"Sheng Li Xue Bao: [acta Physiologica Sinica]"},{"key":"10.1016\/j.intimp.2024.113155_b0060","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1096\/fj.201601346R","article-title":"The role of CB1 in intestinal permeability and inflammation","volume":"31","author":"Karwad","year":"2017","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2024.113155_b0065","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.bbrc.2020.02.173","article-title":"Effect of monoacylglycerol lipase inhibition on intestinal permeability in chronic stress model","volume":"525","author":"Wang","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2024.113155_b0070","first-page":"591","article-title":"Modulation of the endocannabinoid system by the fatty acid amide hydrolase, monoacylglycerol and diacylglycerol lipase inhibitors as an attractive target for secretory diarrhoea therapy","volume":"68","author":"Wasilewski","year":"2017","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0075","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0016-5085(03)00892-8","article-title":"A endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice","volume":"125","author":"Izzo","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.intimp.2024.113155_b0080","doi-asserted-by":"crossref","first-page":"7245","DOI":"10.3390\/molecules28217245","article-title":"Novel MAGL Inhibitors Alleviate LPS-Induced Acute Kidney Injury by Inhibiting NLRP3 Inflammatory Vesicles, Modulating Intestinal Flora, Repairing the Intestinal Barrier, and Interfering with Serum Metabolism","volume":"28","author":"Xiang","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.intimp.2024.113155_b0085","first-page":"2711","article-title":"Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation, FASEB journal: official publication of the Federation of American Societies for","volume":"25","author":"Alhouayek","year":"2011","journal-title":"Exp. Biol."},{"key":"10.1016\/j.intimp.2024.113155_b0090","doi-asserted-by":"crossref","first-page":"986","DOI":"10.3390\/molecules22060986","article-title":"Potential of Icariin Metabolites from Epimedium koreanum Nakai as Antidiabetic Therapeutic Agents","volume":"22","author":"Kim","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.intimp.2024.113155_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113180","article-title":"Anti-inflammatory and immunoregulatory effects of icariin and icaritin","volume":"151","author":"Bi","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.113155_b0100","doi-asserted-by":"crossref","first-page":"382","DOI":"10.5152\/tjg.2021.20282","article-title":"Icariin inhibits intestinal inflammation of DSS-induced colitis mice through modulating gut microbiota abundance and modulating p-p65\/p65 molecule","volume":"32","author":"Zhang","year":"2021","journal-title":"Turk. J. Gastroenterol."},{"key":"10.1016\/j.intimp.2024.113155_b0105","doi-asserted-by":"crossref","unstructured":"C.H. Sun, N.N. Cao, Q.G. Wang, N. Liu, T.Y. Y, S.R. Li, L.H. Pan, J.C. Yao, L. Zhang, M.F. Liu, G.M. Zhang, X.F. Xiao, C.X. L, Icaritin induces resolution of inflammation by targeting cathepsin B to prevents mice from ischemia-reperfusion injury, International Immunopharmacology 116 (2023) 109850, DOI: 10.1016\/j.intimp.2023.109850.","DOI":"10.1016\/j.intimp.2023.109850"},{"key":"10.1016\/j.intimp.2024.113155_b0110","first-page":"47","article-title":"Sensitive and rapid method to quantify icaritin and desmethylicaritin in human serum using gas chromatography-mass spectrometry, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life","volume":"857","author":"Shen","year":"2007","journal-title":"Sciences"},{"key":"10.1016\/j.intimp.2024.113155_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.intimp.2012.02.011","article-title":"Icaritin inhibits T cell activation and prolongs skin allograft survival in mice","volume":"13","author":"Li","year":"2012","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0120","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.intimp.2013.03.025","article-title":"Icaritin exhibits anti-inflammatory effects in the mouse peritoneal macrophages and peritonitis model","volume":"16","author":"Lai","year":"2013","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0125","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/s41401-022-00933-3","article-title":"Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9\/MAPK and neutrophil recruitment inactivation","volume":"44","author":"Zha","year":"2023","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.intimp.2024.113155_b0130","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/nmo.12563","article-title":"The effect of FAAH, MAGL, and dual FAAH\/MAGL inhibition on inflammatory and colorectal distension-induced visceral pain models in rodents","volume":"27","author":"Sakin","year":"2015","journal-title":"Neurogastroenterol. Motility."},{"key":"10.1016\/j.intimp.2024.113155_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112810","article-title":"Network pharmacology and experimental verification revealing valnemulin alleviates DSS-induced ulcerative colitis by inhibiting intestinal senescence","volume":"141","author":"Wang","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117668","article-title":"Network pharmacology and experimental verification to explore the anti-superficial thrombophlebitis mechanism of Mailuo shutong pill","volume":"322","author":"Li","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0145","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1186\/s12967-024-05122-w","article-title":"Short-chain fatty acid-producing bacterial strains attenuate experimental ulcerative colitis by promoting M2 macrophage polarization via JAK\/STAT3\/FOXO3 axis inactivation","volume":"22","author":"Zhao","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2024.113155_b0150","article-title":"Jingfang granules ameliorate inflammation and immune disorders in mice exposed to low temperature and high humidity by restoring the dysregulation of gut microbiota and fecal metabolites","volume":"165","author":"Li","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2024.113155_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112846","article-title":"Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota","volume":"140","author":"Qiu","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0160","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.3390\/molecules21111597","article-title":"Kuwanon G Preserves LPS-Induced Disruption of Gut Epithelial Barrier In Vitro","volume":"21","author":"Guo","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.intimp.2024.113155_b0165","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1136\/gutjnl-2018-316906","article-title":"Tight junction proteins in gastrointestinal and liver disease","volume":"68","author":"Zeisel","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.intimp.2024.113155_b0170","doi-asserted-by":"crossref","first-page":"5800","DOI":"10.3748\/wjg.v25.i38.5800","article-title":"Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis","volume":"25","author":"Ren","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.intimp.2024.113155_b0175","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.21037\/apm-21-250","article-title":"<i>Tiaochang Xiaoyan<\/i> <i>extract tablets<\/i> ameliorate chronic inflammation by activating macrophage lysosomes in chronic colitis rats, Annals of","volume":"10","author":"Wang","year":"2021","journal-title":"Palliat. Med."},{"key":"10.1016\/j.intimp.2024.113155_b0180","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1172\/JCI28804","article-title":"Proteasome-mediated degradation of I\u03baB\u03b1 and processing of p105 in Crohn disease and ulcerative colitis","volume":"116","author":"Visekruna","year":"2006","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.intimp.2024.113155_b0185","doi-asserted-by":"crossref","first-page":"3815","DOI":"10.4049\/jimmunol.147.11.3815","article-title":"IL-10 inhibits cytokine production by activated macrophages","volume":"147","author":"Fiorentino","year":"1991","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2024.113155_b0190","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41564-018-0306-4","article-title":"Gut microbiome structure and metabolic activity in inflammatory bowel disease","volume":"4","author":"Franzosa","year":"2019","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.intimp.2024.113155_b0195","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.freeradbiomed.2019.04.005","article-title":"Gut microbiota modulation and anti-inflammatory properties of anthocyanins from the fruits of Lycium ruthenicum Murray in dextran sodium sulfate-induced colitis in mice","volume":"136","author":"Peng","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2024.113155_b0200","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s40104-021-00612-z","article-title":"Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets","volume":"12","author":"Gao","year":"2021","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.intimp.2024.113155_b0205","doi-asserted-by":"crossref","first-page":"81760","DOI":"10.3389\/fimmu.2022.817600","article-title":"Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism","volume":"13","author":"Cheng","year":"2022","journal-title":"Front. Immunol."},{"issue":"11","key":"10.1016\/j.intimp.2024.113155_b0210","doi-asserted-by":"crossref","first-page":"6387","DOI":"10.1039\/D2FO00012A","article-title":"Walnut green husk ethanol extract improves gut microbiota and their metabolites associated with NLRP3 in non-alcoholic steatohepatitis","volume":"13","author":"Fang","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.intimp.2024.113155_b0215","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.chom.2020.12.014","article-title":"A Diamond in the Rough: IgA-Seq Signatures Stratify New Onset IBD","volume":"29","author":"Lima","year":"2021","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.intimp.2024.113155_b0220","doi-asserted-by":"crossref","unstructured":"Geis AL, Fan H, Wu X, Wu S, Huso DL, Wolfe JL, Sears CL, Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis,Cancer discovery,5 (10) 1098\u20131109, DOI: 10.1158\/2159-8290.CD-15-0447.","DOI":"10.1158\/2159-8290.CD-15-0447"},{"key":"10.1016\/j.intimp.2024.113155_b0225","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/s41564-021-01050-3","article-title":"Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatu proteases with disease severity","volume":"7","author":"Mills","year":"2022","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.intimp.2024.113155_b0230","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9186232","article-title":"Quantitative analysis of gut microbiota of uygur and han ethnic chinese patients with ulcerative colitis","volume":"2016","author":"Yao","year":"2016","journal-title":"Gastroenterol. Res. Pract."},{"key":"10.1016\/j.intimp.2024.113155_b0235","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.bcp.2012.12.002","article-title":"Inhibition of Th1\/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin","volume":"85","author":"Tao","year":"2013","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0240","doi-asserted-by":"crossref","first-page":"382","DOI":"10.5152\/tjg.2021.20282","article-title":"Icariin inhibits intestinal inflammation of DSS-induced colitis mice through modulating intestinal flora abundance and modulating p-p65\/p65 molecule","volume":"32","author":"Zhang","year":"2021","journal-title":"Turk. J. Gastroenterol."},{"key":"10.1016\/j.intimp.2024.113155_b0245","doi-asserted-by":"crossref","first-page":"1014117","DOI":"10.3389\/fphar.2022.1014117","article-title":"Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach","volume":"13","author":"Bai","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153538","article-title":"Study of the therapeutic effect of raw and processed Vladimiriae Radix on ulcerative colitis based on gut microbiota, metabolomics and tissue distribution analysis","volume":"85","author":"Yu","year":"2021","journal-title":"Phytomedicine"},{"key":"10.1016\/j.intimp.2024.113155_b0255","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1080\/10408398.2016.1203286","article-title":"Short chain and polyunsaturated fatty acids in host gut health and foodborne bacterial pathogen inhibition","volume":"57","author":"Peng","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.intimp.2024.113155_b0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00394-019-01901-0","article-title":"Dietary intake of fish, n-3 polyunsaturated fatty acids, and risk of inflammatory bowel disease: a systematic review and meta-analysis of observational studies","volume":"59","author":"Mozaffari","year":"2020","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.intimp.2024.113155_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2019.106018","article-title":"Maresin 1 alleviates dextran sulfate sodium-induced ulcerative colitis by regulating NRF2 and TLR4\/NF-kB signaling pathway","volume":"78","author":"Qiu","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0270","first-page":"2751","article-title":"\u03c9-3 and \u03c9-6 Polyunsaturated Fatty Acids","volume":"12","author":"D'Angelo","year":"2020","journal-title":"Obesity and Cancer, Nutrients."},{"issue":"8","key":"10.1016\/j.intimp.2024.113155_b0275","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1097\/MIB.0000000000000790","article-title":"L-Arginine Availability and Metabolism Is Altered in Ulcerative Colitis","volume":"22","author":"Coburn","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"issue":"1","key":"10.1016\/j.intimp.2024.113155_b0280","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/MEG.0b013e328365c372","article-title":"Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries","volume":"26","author":"de Silva","year":"2014","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.intimp.2024.113155_b0285","doi-asserted-by":"crossref","first-page":"7520","DOI":"10.1039\/D3FO01094E","article-title":"Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis via the TLR4\/MyD88\/NF-\u03baB pathway and gut microbiota modulation","volume":"14","author":"Zhu","year":"2023","journal-title":"Food Funct."},{"key":"10.1016\/j.intimp.2024.113155_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115690","article-title":"Xianglian Pill attenuates ulcerative colitis through TLR4\/MyD88\/NF-\u03baB signaling pathway","volume":"300","author":"Dai","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2019.112361","article-title":"Phillygenin inhibits LPS-induced activation and inflammation of LX2 cells by TLR4\/MyD88\/NF-\u03baB signaling pathway","volume":"248","author":"Hu","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2024.113155_b0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113772","article-title":"Icaritin: A phytomolecule with enormous pharmacological values","volume":"213","author":"Huong","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.intimp.2024.113155_b0305","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bcp.2018.07.036","article-title":"Monoacylglycerol lipase (MAGL) as a promising therapeutic target","volume":"157","author":"Gil-Ord\u00f3\u00f1ez","year":"2018","journal-title":"Biochem. Pharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924016771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924016771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T02:55:52Z","timestamp":1728010552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924016771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":61,"alternative-id":["S1567576924016771"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113155","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synergistic effect and mechanism of monoacylglycerol lipase inhibitor and Icaritin in the treatment of ulcerative colitis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113155","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113155"}}