{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:35:39Z","timestamp":1789148139890,"version":"build-2803163510"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2019YFA0802604"],"award-info":[{"award-number":["2019YFA0802604"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["20Y11908000"],"award-info":[{"award-number":["20Y11908000"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81501277"],"award-info":[{"award-number":["81501277"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.intimp.2024.113200","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T01:09:08Z","timestamp":1727399348000},"page":"113200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"PB","title":["METTL14 depletion induces trophoblast cell dysfunction by inhibiting miR\u201321-5p processing in an m6A-dependent manner"],"prefix":"10.1016","volume":"142","author":[{"given":"Xiaoli","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaona","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpeng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"519","key":"10.1016\/j.intimp.2024.113200_b0005","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/nature14281","article-title":"N6-methyladenosine marks primary microRNAs for processing","volume":"26","author":"Alarcon","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2024.113200_b0010","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12920-020-00730-z","article-title":"Identification of genes and miRNA associated with idiopathic recurrent pregnancy loss: an exploratory data mining study","volume":"13","author":"Bahia","year":"2020","journal-title":"BMC Med. Genomics"},{"key":"10.1016\/j.intimp.2024.113200_b0015","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/978-1-4939-3271-9_8","article-title":"Lentivirus Production and Purification","volume":"1382","author":"Benskey","year":"2016","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.intimp.2024.113200_b0020","doi-asserted-by":"crossref","first-page":"04013","DOI":"10.7189\/jogh.14.04013","article-title":"Factors and outcomes for placental anomalies: An umbrella review of systematic reviews and meta-analyses","volume":"14","author":"Fan","year":"2024","journal-title":"J. Glob. Health"},{"key":"10.1016\/j.intimp.2024.113200_b0025","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1126\/science.1261417","article-title":"Stem cells. m6A mRNA methylation facilitates resolution of naive pluripotency toward differentiation","volume":"347","author":"Geula","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.intimp.2024.113200_b0030","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12943-019-1036-9","article-title":"METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221\/222 maturation in m6A-dependent manner","volume":"22","author":"Han","year":"2019","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.intimp.2024.113200_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2020.145334","article-title":"Differentially expressed circulating microRNAs associated with idiopathic recurrent pregnancy loss","volume":"768","author":"Jairajpuri","year":"2021","journal-title":"Gene"},{"key":"10.1016\/j.intimp.2024.113200_b0040","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/s12964-023-01371-2","article-title":"YAP-mediated trophoblast dysfunction: the common pathway underlying pregnancy complications","volume":"21","author":"Lin","year":"2023","journal-title":"Cell Commun. Signal"},{"key":"10.1016\/j.intimp.2024.113200_b0045","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s10815-024-03036-6","article-title":"Unraveling the molecular mechanisms driving enhanced invasion capability of extravillous trophoblast cells: a comprehensive review","volume":"41","author":"Lin","year":"2024","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.intimp.2024.113200_b0050","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.ymthe.2024.01.037","article-title":"m6A epitranscriptomic and epigenetic crosstalk in cardiac fibrosis","volume":"32","author":"Liu","year":"2024","journal-title":"Mol. Ther."},{"key":"10.1016\/j.intimp.2024.113200_b0055","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T))","volume":"25","author":"Livak","year":"2001","journal-title":"Method. Methods"},{"key":"10.1016\/j.intimp.2024.113200_b0060","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/s41577-022-00777-2","article-title":"Local immune recognition of trophoblast in early human pregnancy: controversies and questions","volume":"23","author":"Moffett","year":"2023","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2024.113200_b0065","doi-asserted-by":"crossref","first-page":"7239","DOI":"10.1093\/nar\/gkab378","article-title":"A comprehensive review of m6A\/m6Am RNA methyltransferase structures","volume":"49","author":"Oerum","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.intimp.2024.113200_b0070","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/cas.16048","article-title":"RNA methylation in inflammatory bowel disease","volume":"115","author":"Ozato","year":"2024","journal-title":"Cancer Sci."},{"key":"10.1016\/j.intimp.2024.113200_b0075","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/978-1-4939-7540-2_9","article-title":"Identifying miRNA Targets Using AGO-RIPseq","volume":"1720","author":"Petri","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.intimp.2024.113200_b0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s43556-023-00139-x","article-title":"RNA modification: mechanisms and therapeutic targets","volume":"4","author":"Qiu","year":"2023","journal-title":"Mol Biomed"},{"key":"10.1016\/j.intimp.2024.113200_b0085","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.molcel.2023.01.006","article-title":"RNA m6A methylation across the transcriptome","volume":"83","author":"Sendinc","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.intimp.2024.113200_b0090","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4269\/ajtmh.23-0399","article-title":"Understanding Antenatal Care Service Quality for Malaria in Pregnancy through Supportive Supervision Data in Tanzania","volume":"110","author":"Tesha","year":"2024","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.intimp.2024.113200_b0095","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1042\/BST20230574","article-title":"RNA m6A modification, signals for degradation or stabilisation?","volume":"52","author":"Wei","year":"2024","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.intimp.2024.113200_b0100","doi-asserted-by":"crossref","first-page":"e52348","DOI":"10.15252\/embr.202052348","article-title":"m6A methylation promotes white-to-beige fat transition by facilitating Hif1a translation","volume":"4","author":"Wu","year":"2021","journal-title":"EMBO Rep."},{"key":"10.1016\/j.intimp.2024.113200_b0105","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1007\/s13258-022-01309-x","article-title":"METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A\/VEGF pathway","volume":"44","author":"Ye","year":"2022","journal-title":"Genes Genomics"},{"key":"10.1016\/j.intimp.2024.113200_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2021.103341","article-title":"Exploration of the potential roles of m6A regulators in the uterus in pregnancy and infertility","volume":"146","author":"Zhao","year":"2021","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.intimp.2024.113200_b0115","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.7150\/ijbs.46144","article-title":"MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization","volume":"16","author":"Zhu","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.intimp.2024.113200_b0120","first-page":"27","article-title":"Increased miR-6875-5p inhibits plasmacytoid dendritic cell differentiation via the STAT3\/E2-2 pathway in recurrent spontaneous abortion","volume":"8","author":"Zhu","year":"2021","journal-title":"Mol. Hum. Reprod."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924017223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924017223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T06:00:00Z","timestamp":1734069600000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924017223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":24,"alternative-id":["S1567576924017223"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113200","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"METTL14 depletion induces trophoblast cell dysfunction by inhibiting miR\u201321-5p processing in an m6A-dependent manner","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113200"}}