{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:01:25Z","timestamp":1789668085522,"version":"4.0.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2019xkj041"],"award-info":[{"award-number":["2019xkj041"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2020GQFY06"],"award-info":[{"award-number":["2020GQFY06"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.intimp.2024.113803","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T01:56:07Z","timestamp":1733968567000},"page":"113803","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Inhibition of CCR2 attenuates NLRP3-dependent pyroptosis after myocardial ischaemia\u2013reperfusion in rats via the NF-kB pathway"],"prefix":"10.1016","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7332-6296","authenticated-orcid":false,"given":"Yun","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyun","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.intimp.2024.113803_b0005","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tcm.2022.02.005","article-title":"Myocardial ischemia-reperfusion injury and the influence of inflammation","volume":"33","author":"Algoet","year":"2023","journal-title":"Trends Cardiovasc Med"},{"issue":"2","key":"10.1016\/j.intimp.2024.113803_b0010","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1161\/CIR.0000000000000985","article-title":"Mechanical Complications of Acute Myocardial Infarction: A Scientific Statement From the American Heart Association","volume":"144","author":"Damluji","year":"2021","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.intimp.2024.113803_b0015","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/s41569-020-0403-y","article-title":"Myocardial ischaemia-reperfusion injury and cardioprotection in perspective","volume":"17","author":"Heusch","year":"2020","journal-title":"Nat Rev Cardiol"},{"issue":"1","key":"10.1016\/j.intimp.2024.113803_b0020","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.apsb.2022.08.007","article-title":"Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies","volume":"13","author":"Yanpiset","year":"2023","journal-title":"Acta Pharm Sin B"},{"issue":"20","key":"10.1016\/j.intimp.2024.113803_b0025","doi-asserted-by":"crossref","DOI":"10.3390\/cells11203271","article-title":"Research Progress on the Role of Pyroptosis in Myocardial Ischemia-Reperfusion Injury","volume":"11","author":"Liu","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.intimp.2024.113803_b0030","article-title":"Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications","volume":"13","author":"Zhang","year":"2022","journal-title":"Front Immunol"},{"issue":"48","key":"10.1016\/j.intimp.2024.113803_b0035","doi-asserted-by":"crossref","first-page":"3937","DOI":"10.1093\/eurheartj\/ehz283","article-title":"Immunotherapy for cardiovascular disease","volume":"40","author":"Lutgens","year":"2019","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.intimp.2024.113803_b0040","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/s41419-022-04610-5","article-title":"Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma","volume":"13","author":"Ling","year":"2022","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.intimp.2024.113803_b0045","doi-asserted-by":"crossref","first-page":"6441","DOI":"10.2147\/IJN.S178650","article-title":"Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction","volume":"13","author":"Wang","year":"2018","journal-title":"Int J Nanomedicine"},{"issue":"4","key":"10.1016\/j.intimp.2024.113803_b0050","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s00395-020-0803-5","article-title":"Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy","volume":"115","author":"Lubos","year":"2020","journal-title":"Basic Res Cardiol"},{"issue":"3","key":"10.1016\/j.intimp.2024.113803_b0055","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1002\/hep.30249","article-title":"Pharmacological Inhibition of CCR2\/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice","volume":"69","author":"Ambade","year":"2019","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.intimp.2024.113803_b0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010395","article-title":"Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates","volume":"18","author":"Corry","year":"2022","journal-title":"PLoS Pathog"},{"issue":"5","key":"10.1016\/j.intimp.2024.113803_b0065","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1001\/jamacardio.2020.5392","article-title":"Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies","volume":"6","author":"Georgakis","year":"2021","journal-title":"JAMA Cardiol"},{"issue":"8","key":"10.1016\/j.intimp.2024.113803_b0070","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1161\/01.RES.0000163017.13772.3a","article-title":"CCL2\/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts","volume":"96","author":"Dewald","year":"2005","journal-title":"Circ Res"},{"issue":"1","key":"10.1016\/j.intimp.2024.113803_b0075","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/s12974-022-02676-8","article-title":"Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K\/Akt pathway","volume":"19","author":"Tian","year":"2022","journal-title":"J Neuroinflammation"},{"issue":"5","key":"10.1016\/j.intimp.2024.113803_b0080","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1136\/annrheumdis-2016-210426","article-title":"CCL2\/CCR2, but not CCL5\/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis","volume":"76","author":"Raghu","year":"2017","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"10.1016\/j.intimp.2024.113803_b0085","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1681\/ASN.2019010068","article-title":"Tubular GM-CSF Promotes Late MCP-1\/CCR2-Mediated Fibrosis and Inflammation after Ischemia\/Reperfusion Injury","volume":"30","author":"Xu","year":"2019","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"10.1016\/j.intimp.2024.113803_b0090","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/hep.29544","article-title":"Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis","volume":"67","author":"Krenkel","year":"2018","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.intimp.2024.113803_b0095","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.jhep.2019.09.033","article-title":"PSMP\/MSMP promotes hepatic fibrosis through CCR2 and represents a novel therapeutic target","volume":"72","author":"She","year":"2020","journal-title":"J Hepatol"},{"issue":"5","key":"10.1016\/j.intimp.2024.113803_b0100","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1161\/CIRCRESAHA.124.324106","article-title":"Lysozyme 1 Inflamed CCR2(+) Macrophages Promote Obesity-Induced Cardiac Dysfunction","volume":"135","author":"Zhang","year":"2024","journal-title":"Circ Res"},{"key":"10.1016\/j.intimp.2024.113803_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117516","article-title":"Tianhuang formula ameliorates liver fibrosis by inhibiting CCL2-CCR2 axis and MAPK\/NF-kappaB signaling pathway","volume":"321","author":"Lan","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.intimp.2024.113803_b0110","article-title":"CCR2(+) Macrophages Promote Orthodontic Tooth Movement and Alveolar Bone Remodeling","volume":"13","author":"Xu","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.intimp.2024.113803_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.108934","article-title":"CD30L is involved in the regulation of the inflammatory response through inducing homing and differentiation of monocytes via CCL2\/CCR2 axis and NF-kappaB pathway in mice with colitis","volume":"110","author":"Mei","year":"2022","journal-title":"Int Immunopharmacol"},{"issue":"6","key":"10.1016\/j.intimp.2024.113803_b0120","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1161\/CIRCRESAHA.121.319478","article-title":"Targeting CaMKII-delta9 Ameliorates Cardiac Ischemia\/Reperfusion Injury by Inhibiting Myocardial Inflammation","volume":"130","author":"Yao","year":"2022","journal-title":"Circ Res"},{"key":"10.1016\/j.intimp.2024.113803_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104744","article-title":"Interleukin-34-NF-kappaB signaling aggravates myocardial ischemic\/reperfusion injury by facilitating macrophage recruitment and polarization","volume":"95","author":"Zhuang","year":"2023","journal-title":"EBioMedicine"},{"key":"10.1016\/j.intimp.2024.113803_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154093","article-title":"Nuanxinkang protects against ischemia\/reperfusion-induced heart failure through regulating IKKbeta\/IkappaBalpha\/NF-kappaB-mediated macrophage polarization","volume":"101","author":"Dong","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.intimp.2024.113803_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.111668","article-title":"Diannexin alleviates myocardial ischemia-reperfusion injury by orchestrating cardiomyocyte oxidative damage, macrophage polarization and fibrotic process by TLR4-NF-kB-mediated inactivation of NLRP3 inflammasome","volume":"130","author":"Zhang","year":"2024","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"10.1016\/j.intimp.2024.113803_b0140","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s00395-022-00968-x","article-title":"Spinal cord astrocytes regulate myocardial ischemia-reperfusion injury","volume":"117","author":"Wu","year":"2022","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.intimp.2024.113803_b0145","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.trsl.2020.06.009","article-title":"IcyHot analgesic topical cream limits cardiac injury in rodents","volume":"227","author":"Wu","year":"2021","journal-title":"Transl Res"},{"issue":"8","key":"10.1016\/j.intimp.2024.113803_b0150","doi-asserted-by":"crossref","first-page":"303","DOI":"10.31083\/j.fbl2908303","article-title":"Inhibition of Macrophage Recruitment to Heart Valves Mediated by the C-C Chemokine Receptor Type 2 Attenuates Valvular Inflammation Induced by Group A Streptococcus in Lewis Rats","volume":"29","author":"Bai","year":"2024","journal-title":"Front Biosci (landmark Ed)"},{"key":"10.1016\/j.intimp.2024.113803_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107947","article-title":"The roles of MCP-1\/CCR2 mediated macrophage recruitment and polarization in bladder outlet obstruction (BOO) induced bladder remodeling","volume":"99","author":"Wang","year":"2021","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"10.1016\/j.intimp.2024.113803_b0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12931-019-0973-6","article-title":"Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells","volume":"20","author":"Kubo","year":"2019","journal-title":"Respir Res"},{"key":"10.1016\/j.intimp.2024.113803_b0165","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3389\/fnmol.2017.00247","article-title":"MPTP-Induced Dopamine Depletion in Basolateral Amygdala via Decrease of D2R Activation Suppresses GABA(A) Receptors Expression and LTD Induction Leading to Anxiety-Like Behaviors","volume":"10","author":"Zhang","year":"2017","journal-title":"Front Mol Neurosci"},{"issue":"17","key":"10.1016\/j.intimp.2024.113803_b0170","doi-asserted-by":"crossref","first-page":"7237","DOI":"10.7150\/thno.77345","article-title":"MMP 9-instructed assembly of bFGF nanofibers in ischemic myocardium to promote heart repair","volume":"12","author":"Wang","year":"2022","journal-title":"Theranostics"},{"key":"10.1016\/j.intimp.2024.113803_b0175","first-page":"1)","article-title":"V1-Cal hydrogelation enhances its effects on ventricular remodeling reduction and cardiac function improvement post myocardial infarction","volume":"433(Pt","author":"Wang","year":"2022","journal-title":"Chem Eng J"},{"key":"10.1016\/j.intimp.2024.113803_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2024.115318","article-title":"The role of CCL2\/CCR2 axis in cancer and inflammation: The next frontier in nanomedicine","author":"Pozzi","year":"2024","journal-title":"Adv Drug Deliv Rev"},{"issue":"2","key":"10.1016\/j.intimp.2024.113803_b0185","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/CIRCRESAHA.118.314028","article-title":"Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury","volume":"124","author":"Bajpai","year":"2019","journal-title":"Circ Res"},{"issue":"4","key":"10.1016\/j.intimp.2024.113803_b0190","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0008-6363(00)00142-5","article-title":"Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure","volume":"47","author":"Damas","year":"2000","journal-title":"Cardiovasc Res"},{"issue":"23","key":"10.1016\/j.intimp.2024.113803_b0195","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1161\/CIRCULATIONAHA.121.058615","article-title":"Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte\/Macrophage Suppression","volume":"146","author":"Manta","year":"2022","journal-title":"Circulation"},{"issue":"19","key":"10.1016\/j.intimp.2024.113803_b0200","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1093\/eurheartj\/ehac094","article-title":"Targeting the CCL2-CCR2 axis for atheroprotection","volume":"43","author":"Georgakis","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.intimp.2024.113803_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119034","article-title":"Role of CCL2\/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches","volume":"269","author":"Moadab","year":"2021","journal-title":"Life Sci"},{"issue":"6","key":"10.1016\/j.intimp.2024.113803_b0210","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1161\/ATVBAHA.121.316091","article-title":"Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability","volume":"41","author":"Georgakis","year":"2021","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.intimp.2024.113803_b0215","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1161\/01.CIR.0000049742.68848.99","article-title":"Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes","volume":"107","author":"de Lemos","year":"2003","journal-title":"Circulation"},{"issue":"6696","key":"10.1016\/j.intimp.2024.113803_b0220","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/29788","article-title":"Decreased lesion formation in CCR2-\/- mice reveals a role for chemokines in the initiation of atherosclerosis","volume":"394","author":"Boring","year":"1998","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.intimp.2024.113803_b0225","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1161\/01.RES.0000149518.86865.3e","article-title":"Crucial role of the CCL2\/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets","volume":"95","author":"Schober","year":"2004","journal-title":"Circ Res"},{"issue":"14","key":"10.1016\/j.intimp.2024.113803_b0230","article-title":"M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair","volume":"10","author":"Li","year":"2023","journal-title":"Adv Sci (weinh)"},{"issue":"2","key":"10.1016\/j.intimp.2024.113803_b0235","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1161\/CIRCRESAHA.118.314357","article-title":"The Functional Heterogeneity of Resident Cardiac Macrophages in Myocardial InjuryCCR2(+) Cells Promote Inflammation, Whereas CCR2(-) Cells Protect","volume":"124","author":"Chen","year":"2019","journal-title":"Circ Res"},{"issue":"10","key":"10.1016\/j.intimp.2024.113803_b0240","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41419-021-04143-3","article-title":"Pyroptosis inhibition improves the symptom of acute myocardial infarction","volume":"12","author":"Liu","year":"2021","journal-title":"Cell Death Dis"},{"issue":"3","key":"10.1016\/j.intimp.2024.113803_b0245","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1161\/CIRCRESAHA.120.318629","article-title":"GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I\/R Injury","volume":"129","author":"Shi","year":"2021","journal-title":"Circ Res"},{"issue":"11","key":"10.1016\/j.intimp.2024.113803_b0250","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1016\/j.immuni.2023.10.004","article-title":"Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis","volume":"56","author":"Miao","year":"2023","journal-title":"Immunity"},{"issue":"4","key":"10.1016\/j.intimp.2024.113803_b0255","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/s41569-023-00946-3","article-title":"The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases","volume":"21","author":"Toldo","year":"2024","journal-title":"Nat Rev Cardiol"},{"issue":"8","key":"10.1016\/j.intimp.2024.113803_b0260","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202300281RR","article-title":"CCR2 inhibitor strengthens the adiponectin effects against myocardial injury after infarction","volume":"37","author":"Zheng","year":"2023","journal-title":"FASEB J"},{"issue":"6","key":"10.1016\/j.intimp.2024.113803_b0265","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.amjcard.2010.11.005","article-title":"Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region","volume":"107","author":"Gilbert","year":"2011","journal-title":"Am J Cardiol"},{"issue":"1","key":"10.1016\/j.intimp.2024.113803_b0270","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12872-024-03729-x","article-title":"Coenzyme Q10 mitigates macrophage mediated inflammation in heart following myocardial infarction via the NLRP3\/IL1beta pathway","volume":"24","author":"Pan","year":"2024","journal-title":"BMC Cardiovasc Disord"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924023257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576924023257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:10:46Z","timestamp":1777619446000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576924023257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":54,"alternative-id":["S1567576924023257"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113803","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of CCR2 attenuates NLRP3-dependent pyroptosis after myocardial ischaemia\u2013reperfusion in rats via the NF-kB pathway","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2024.113803","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113803"}}