{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:51:31Z","timestamp":1784069491833,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.intimp.2025.114224","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T22:18:17Z","timestamp":1738880297000},"page":"114224","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Universal Thermal Climate Index influences on uric acid levels and hyperuricemia: Insights from a large-scale population study"],"prefix":"10.1016","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5140-5521","authenticated-orcid":false,"given":"Yufen","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minya","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linyan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0873-6824","authenticated-orcid":false,"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2025.114224_b0005","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/art.40807","article-title":"Contemporary prevalence of gout and hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007-2016","volume":"71","author":"Chen-Xu","year":"2019","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.intimp.2025.114224_b0010","article-title":"Prevalence of hyperuricemia among Chinese adults: findings from two nationally representative cross-sectional surveys in 2015-16 and 2018-19","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.114224_b0015","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-88631-8","article-title":"Possible burden of hyperuricaemia on mortality in a community-based population: a large-scale cohort study","volume":"11","author":"Otaki","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2025.114224_b0020","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.2215\/CJN.05190420","article-title":"Effect of Urate-lowering therapy on cardiovascular and kidney outcomes: a systematic review and meta-analysis","volume":"15","author":"Chen","year":"2020","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.1016\/j.intimp.2025.114224_b0025","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-47805-4","article-title":"Large-scale cross-ancestry genome-wide meta-analysis of serum urate","volume":"15","author":"Cho","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2025.114224_b0030","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/art.23245","article-title":"Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and Nutrition Examination Survey","volume":"59","author":"Choi","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.intimp.2025.114224_b0035","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/art.20761","article-title":"Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey","volume":"52","author":"Choi","year":"2005","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.intimp.2025.114224_b0040","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1002\/art.20821","article-title":"Beer, liquor, and wine consumption and serum uric acid level: the Third National Health and Nutrition Examination Survey","volume":"51","author":"Choi","year":"2004","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.intimp.2025.114224_b0045","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1093\/ajcn\/87.5.1480","article-title":"Effects of diet, physical activity and performance, and body weight on incident gout in ostensibly healthy, vigorously active men","volume":"87","author":"Williams","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.intimp.2025.114224_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113377","article-title":"Environmental factors and risk of gout","volume":"212","author":"Wu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.intimp.2025.114224_b0055","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.envres.2015.07.007","article-title":"Heat stress, dehydration, and kidney function in sugarcane cutters in El Salvador\u2013a cross-shift study of workers at risk of Mesoamerican nephropathy","volume":"142","author":"Garc\u00eda-Trabanino","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.intimp.2025.114224_b0060","doi-asserted-by":"crossref","first-page":"13797","DOI":"10.1007\/s11356-021-16580-w","article-title":"Association between non-optimal temperature and hospitalizations for gout in Anqing, China: a time-series analysis","volume":"29","author":"He","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.intimp.2025.114224_b0065","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/aje\/kwu147","article-title":"Relation of temperature and humidity to the risk of recurrent gout attacks","volume":"180","author":"Neogi","year":"2014","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.intimp.2025.114224_b0070","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1007\/s10067-017-3591-z","article-title":"Seasonal variations of urate in a Swedish adult population","volume":"36","author":"\u00c5kerblom","year":"2017","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.intimp.2025.114224_b0075","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1136\/ard.2008.096693","article-title":"Seasonality and trends in the incidence and prevalence of gout in England and Wales 1994-2007","volume":"68","author":"Elliot","year":"2009","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.intimp.2025.114224_b0080","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3346\/jkms.2015.30.3.240","article-title":"Seasonality of gout in Korea: a multicenter study","volume":"30","author":"Choi","year":"2015","journal-title":"J. Korean Med. Sci."},{"key":"10.1016\/j.intimp.2025.114224_b0085","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s00484-011-0453-2","article-title":"Comparison of UTCI to selected thermal indices","volume":"56","author":"Blazejczyk","year":"2012","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.intimp.2025.114224_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.138969","article-title":"Predictive value of three thermal comfort indices in low temperatures on cardiovascular morbidity in the Iberian Peninsula","volume":"729","author":"Santurt\u00fan","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.intimp.2025.114224_b0095","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.scitotenv.2019.06.280","article-title":"UTCI as a bio-meteorological tool in the assessment of cold-induced stress as a risk factor for hypertension","volume":"688","author":"Skutecki","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.intimp.2025.114224_b0100","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s00484-019-01740-y","article-title":"Applicability of the universal thermal climate index for predicting the outbreaks of respiratory tract infections: a mathematical modeling approach","volume":"63","author":"Romaszko","year":"2019","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.intimp.2025.114224_b0105","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00484-011-0454-1","article-title":"Deriving the operational procedure for the Universal Thermal Climate Index (UTCI)","volume":"56","author":"Br\u00f6de","year":"2012","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.intimp.2025.114224_b0110","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1053\/j.ajkd.2017.12.009","article-title":"Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a Scientific Workshop Organized by the National Kidney Foundation","volume":"71","author":"Johnson","year":"2018","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.intimp.2025.114224_b0115","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1230562","article-title":"Seasonal variations for newly prescribed urate-lowering drugs for asymptomatic hyperuricemia and gout in Japan","volume":"15","author":"Kurajoh","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.114224_b0120","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/ejcn.2015.224","article-title":"Seasonality of food groups and total energy intake: a systematic review and meta-analysis","volume":"70","author":"Stelmach-Mardas","year":"2016","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.intimp.2025.114224_b0125","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00484-004-0240-4","article-title":"Seasonality of alcohol-related phenomena in Estonia","volume":"49","author":"Silm","year":"2005","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.intimp.2025.114224_b0130","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.metabol.2003.11.017","article-title":"Recent trends of hyperuricemia and obesity in Japanese male adolescents, 1991 through 2002","volume":"53","author":"Ogura","year":"2004","journal-title":"Metabolism"},{"key":"10.1016\/j.intimp.2025.114224_b0135","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1007\/s40520-019-01137-2","article-title":"Association between serum uric acid levels and coronary artery disease in different age and gender: a cross-sectional study","volume":"31","author":"Sun","year":"2019","journal-title":"Aging Clin. Exp. Res."},{"key":"10.1016\/j.intimp.2025.114224_b0140","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1056\/NEJMp048015","article-title":"Uric acid and diet\u2014insights into the epidemic of cardiovascular disease","volume":"350","author":"Johnson","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.intimp.2025.114224_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.152020","article-title":"Are the levels of uric acid associated with biometeorological conditions?","volume":"819","author":"Romaszko","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.intimp.2025.114224_b0150","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.diabet.2016.01.002","article-title":"Seasonality and temperature effects on fasting plasma glucose: a population-based longitudinal study in China","volume":"42","author":"Li","year":"2016","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.intimp.2025.114224_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145046","article-title":"Effects of cold and hot temperature on metabolic indicators in adults from a prospective cohort study","volume":"772","author":"Zheng","year":"2021","journal-title":"Sci. Total Environ."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925002140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925002140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T11:53:08Z","timestamp":1739879588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925002140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":31,"alternative-id":["S1567576925002140"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114224","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Universal Thermal Climate Index influences on uric acid levels and hyperuricemia: Insights from a large-scale population study","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114224","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114224"}}