{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:45:19Z","timestamp":1784004319579,"version":"3.55.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2024NSFJQ0005"],"award-info":[{"award-number":["2024NSFJQ0005"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2024NSFSC0029"],"award-info":[{"award-number":["2024NSFSC0029"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2023NSFSC1684"],"award-info":[{"award-number":["2023NSFSC1684"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2023NSFSC1217"],"award-info":[{"award-number":["2023NSFSC1217"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2021YFYZ0003"],"award-info":[{"award-number":["2021YFYZ0003"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2023NSFSC0176"],"award-info":[{"award-number":["2023NSFSC0176"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2023NSFSC1678"],"award-info":[{"award-number":["2023NSFSC1678"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018927","name":"Southwest Minzu University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018927","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32402907"],"award-info":[{"award-number":["32402907"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82404874"],"award-info":[{"award-number":["82404874"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872511"],"award-info":[{"award-number":["31872511"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.intimp.2025.114450","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T15:28:01Z","timestamp":1741793281000},"page":"114450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Mannose-modified erythrocyte membrane-coated Chuanmingshen violaceum polysaccharide PLGA nanoparticles to improve immune responses in mice"],"prefix":"10.1016","volume":"152","author":[{"given":"Shuyao","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinnan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangjiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.intimp.2025.114450_bb0005","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3390\/vaccines12070727","article-title":"An overview of nanoparticle-based delivery platforms for mRNA vaccines for treating cancer","volume":"12","author":"Lin","year":"2024","journal-title":"Vaccines"},{"key":"10.1016\/j.intimp.2025.114450_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1238649","article-title":"Recent advance in the development of tuberculosis vaccines in clinical trials and virus-like particle-based vaccine candidates","volume":"14","author":"Zhou","year":"2023","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2025.114450_bb0015","doi-asserted-by":"crossref","DOI":"10.1002\/btm2.10663","article-title":"Vaccine adjuvants for infectious disease in the clinic","volume":"9","author":"Goetz","year":"2024","journal-title":"Bioeng. Transl. Med."},{"issue":"3","key":"10.1016\/j.intimp.2025.114450_bb0020","doi-asserted-by":"crossref","DOI":"10.1002\/wnan.1967","article-title":"The development of nanocarriers for natural products","volume":"16","author":"Huang","year":"2024","journal-title":"Wires. Nanomed. Nanobi."},{"key":"10.1016\/j.intimp.2025.114450_bb0025","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ijbiomac.2016.01.002","article-title":"Extraction, characterization and antioxidant activities of polysaccharides of Chuanminshen violaceum","volume":"86","author":"Dong","year":"2016","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.intimp.2025.114450_bb0030","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.carbpol.2016.10.040","article-title":"Antioxidant activities of the polysaccharides of Chuanminshen violaceum","volume":"157","author":"Fan","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.intimp.2025.114450_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118357","article-title":"Extraction, characterization and intestinal anti-inflammatory and anti-oxidative activities of polysaccharide from stems and leaves of Chuanminshen violaceum M. L. Sheh & R. H. Shan","volume":"332","author":"JiZe","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.intimp.2025.114450_bb0040","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3390\/antiox8080266","article-title":"Analysis of methanolic extracts and crude polysaccharides from the leaves of Chuanminshen violaceum and their antioxidant activities","volume":"8","author":"Lin","year":"2019","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.intimp.2025.114450_bb0045","first-page":"558","article-title":"Effect of Chuanminshen violaceum polysaccharides and its sulfated derivatives on immunosuppression induced by cyclophosphamide in mice","volume":"8","author":"Zhao","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.intimp.2025.114450_bb0050","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.ijbiomac.2015.04.044","article-title":"Chuanminshen violaceum polysaccharides improve the immune responses of foot-and-mouth disease vaccine in mice","volume":"78","author":"Feng","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.intimp.2025.114450_bb0055","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.ijbiomac.2019.09.151","article-title":"Structural characterization, antioxidant activity, and immunomodulatory activity of non-starch polysaccharides from Chuanminshen violaceum collected from different regions","volume":"143","author":"Lin","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.intimp.2025.114450_bb0060","doi-asserted-by":"crossref","first-page":"5931","DOI":"10.2147\/IJN.S467354","article-title":"Self-assembled aggregated structures of natural products for oral drug delivery","volume":"19","author":"Zhong","year":"2024","journal-title":"Int. J. Nanomedicine"},{"issue":"4","key":"10.1016\/j.intimp.2025.114450_bb0065","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1586\/erm.09.15","article-title":"Current advances in research and clinical applications of PLGA-based nanotechnology","volume":"9","author":"L\u00fc","year":"2009","journal-title":"Expert. Rev. Mol. Diagn."},{"issue":"16","key":"10.1016\/j.intimp.2025.114450_bb0070","doi-asserted-by":"crossref","first-page":"5390","DOI":"10.1039\/D3BM00795B","article-title":"Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery","volume":"11","author":"Malek-Khatabi","year":"2023","journal-title":"Biomater. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2025.114450_bb0075","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1186\/s12951-023-02060-5","article-title":"Red blood cells: a potential delivery system","volume":"21","author":"Chen","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.intimp.2025.114450_bb0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.4155\/tde.11.141","article-title":"Cell-based drug-delivery platforms","volume":"3","author":"Guti\u00e9rrez Mill\u00e1n","year":"2012","journal-title":"Ther. Deliv."},{"issue":"16","key":"10.1016\/j.intimp.2025.114450_bb0085","doi-asserted-by":"crossref","first-page":"1606209","DOI":"10.1002\/adma.201606209","article-title":"Erythrocyte\u2013platelet hybrid membrane coating for enhanced nanoparticle functionalization","volume":"29","author":"Dehaini","year":"2017","journal-title":"Adv. Mater."},{"issue":"6","key":"10.1016\/j.intimp.2025.114450_bb0090","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.1021\/acsnano.2c11965","article-title":"Advances in drug delivery systems based on red blood cells and their membrane-derived nanoparticles","volume":"17","author":"Nguyen","year":"2023","journal-title":"ACS Nano"},{"issue":"19","key":"10.1016\/j.intimp.2025.114450_bb0095","doi-asserted-by":"crossref","first-page":"8884","DOI":"10.1039\/c3nr03064d","article-title":"Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles","volume":"5","author":"Fang","year":"2013","journal-title":"Nanoscale"},{"issue":"8","key":"10.1016\/j.intimp.2025.114450_bb0100","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6528\/aa9ca1","article-title":"Erythrocyte membrane-coated gold nanocages for targeted photothermal and chemical cancer therapy","volume":"29","author":"Zhu","year":"2018","journal-title":"Nanotechnology"},{"issue":"sup1","key":"10.1016\/j.intimp.2025.114450_bb0105","first-page":"926","article-title":"In vitro and in vivo evaluation of folate receptor-targeted a novel magnetic drug delivery system for ovarian cancer therapy","volume":"46","author":"Ak","year":"2018","journal-title":"Artif. Cell Nanomed. B."},{"key":"10.1016\/j.intimp.2025.114450_bb0110","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.765034","article-title":"The mannose receptor: from endocytic receptor and biomarker to regulator of (meta)inflammation","volume":"12","author":"van der Zande","year":"2021","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2025.114450_bb0115","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.3390\/metabo12121205","article-title":"Mannose receptor deficiency impacts bone marrow and circulating immune cells during high fat diet induced obesity","volume":"12","author":"Nour","year":"2022","journal-title":"Metabolites"},{"issue":"9","key":"10.1016\/j.intimp.2025.114450_bb0120","doi-asserted-by":"crossref","first-page":"4552","DOI":"10.4049\/jimmunol.171.9.4552","article-title":"Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program 1","volume":"171","author":"Chieppa","year":"2003","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114450_bb0125","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/eji.200737578","article-title":"Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicity in vitro and in vivo","volume":"38","author":"Sheng","year":"2008","journal-title":"Eur. J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114450_bb0130","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1039\/C4NR03962A","article-title":"Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages","volume":"7","author":"Ortega","year":"2015","journal-title":"Nanoscale"},{"issue":"9","key":"10.1016\/j.intimp.2025.114450_bb0135","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1021\/acsabm.0c00529","article-title":"Glycosylated nanoparticles derived from RAFT polymerization for effective drug delivery to macrophages","volume":"3","author":"Rushworth","year":"2020","journal-title":"ACS Appl. Bio Mater."},{"issue":"10","key":"10.1016\/j.intimp.2025.114450_bb0140","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.3390\/ph15101172","article-title":"Mannosylated polymeric ligands for targeted delivery of antibacterials and their adjuvants to macrophages for the enhancement of the drug efficiency","volume":"15","author":"Zlotnikov","year":"2022","journal-title":"Pharmaceuticals"},{"issue":"45","key":"10.1016\/j.intimp.2025.114450_bb0145","doi-asserted-by":"crossref","first-page":"10054","DOI":"10.1021\/acs.jafc.5b03154","article-title":"A multivariate approach using attenuated total reflectance mid-infrared spectroscopy to measure the surface mannoproteins and \u03b2-glucans of yeast cell walls during wine fermentations","volume":"63","author":"Moore","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.intimp.2025.114450_bb0150","article-title":"Nano-based drug delivery systems for active ingredients from traditional Chinese medicine: harnessing the power of nanotechnology","volume":"15","author":"Zhang","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.114450_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124162","article-title":"Nanocarriers of antigen proteins for vaccine delivery","volume":"659","author":"Lopes Chaves","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.intimp.2025.114450_bb0160","article-title":"Red blood cell-derived materials for cancer therapy: construction, distribution, and applications","volume":"24","author":"Ding","year":"2024","journal-title":"Mater. Today Bio."},{"key":"10.1016\/j.intimp.2025.114450_bb0165","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.jconrel.2024.06.002","article-title":"Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy","volume":"372","author":"Rojekar","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.intimp.2025.114450_bb0170","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.00145","article-title":"Advances in research on Immunoregulation of macrophages by plant polysaccharides","volume":"10","author":"Yin","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.114450_bb0175","first-page":"328","article-title":"Influence of the culture medium on the production of nitric oxide and expression of inducible nitric oxide synthase by activated macrophages in vitro","volume":"5","author":"Kawakami","year":"2016","journal-title":"Biochem. Biophys. Rep."},{"issue":"8","key":"10.1016\/j.intimp.2025.114450_bb0180","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1039\/C6TB02845D","article-title":"Facile fabrication of varisized calcium carbonate microspheres as vaccine adjuvants","volume":"5","author":"Jia","year":"2017","journal-title":"J. Mater. Chem. B"},{"issue":"3","key":"10.1016\/j.intimp.2025.114450_bb0185","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1002\/med.22012","article-title":"The role of toll-like receptors in neuropsychiatric disorders: immunopathology, treatment, and management","volume":"44","author":"Saleki","year":"2024","journal-title":"Med. Res. Rev."},{"issue":"5","key":"10.1016\/j.intimp.2025.114450_bb0190","doi-asserted-by":"crossref","first-page":"562","DOI":"10.3390\/biom14050562","article-title":"MyD88 and its inhibitors in cancer: prospects and challenges","volume":"14","author":"Song","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.intimp.2025.114450_bb0195","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1146\/annurev-immunol-101819-025146","article-title":"Dendritic cell regulation of T helper cells","volume":"39","author":"Yin","year":"2021","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.intimp.2025.114450_bb0200","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev-immunol-061020-053702","article-title":"Cytokine regulation and function in T cells","volume":"39","author":"Dong","year":"2021","journal-title":"Annu. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2025.114450_bb0205","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/s10517-022-05451-0","article-title":"Interaction of human dendritic cells with graphene oxide nanoparticles in vitro","volume":"172","author":"Uzhviyuk","year":"2022","journal-title":"B. Exp. Biol. Med."},{"issue":"11","key":"10.1016\/j.intimp.2025.114450_bb0210","doi-asserted-by":"crossref","DOI":"10.1002\/jcb.30416","article-title":"Autophagy-dependent regulation of MHC-I molecule presentation","volume":"125","author":"Gestal-Mato","year":"2023","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.intimp.2025.114450_bb0215","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jconrel.2024.05.007","article-title":"Spleen-targeted delivery systems and strategies for spleen-related diseases","volume":"370","author":"Huang","year":"2024","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.intimp.2025.114450_bb0220","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1053\/j.semdp.2019.12.003","article-title":"T-cell lymphoproliferative processes in the spleen","volume":"37","author":"Aguilera","year":"2020","journal-title":"Semin. Diagn. Pathol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114450_bb0225","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1021\/acsnano.5b06750","article-title":"Graphene oxides decorated with carnosine as an adjuvant to modulate innate immune and improve adaptive immunity in vivo","volume":"10","author":"Meng","year":"2016","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.intimp.2025.114450_bb0230","doi-asserted-by":"crossref","first-page":"19509","DOI":"10.1038\/srep19509","article-title":"Factors affecting anti-glycan IgG and IgM repertoires in human serum","volume":"6","author":"Muthana","year":"2016","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.intimp.2025.114450_bb0235","article-title":"Cytokines in cancer immunotherapy","volume":"10","author":"Waldmann","year":"2018","journal-title":"CSH Perspect. Biol."},{"issue":"6","key":"10.1016\/j.intimp.2025.114450_bb0240","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S2213-2600(21)00103-X","article-title":"Interleukin-6: obstacles to targeting a complex cytokine in critical illness","volume":"9","author":"McElvaney","year":"2021","journal-title":"Lancet Respir. Med."},{"issue":"29","key":"10.1016\/j.intimp.2025.114450_bb0245","doi-asserted-by":"crossref","first-page":"8385","DOI":"10.1016\/j.biomaterials.2014.05.067","article-title":"Time course study of the antigen-specific immune response to a PLGA microparticle vaccine formulation","volume":"35","author":"Wang","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.intimp.2025.114450_bb0250","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.biomaterials.2017.03.034","article-title":"Synthetic vaccine nanoparticles target to lymph node triggering enhanced innate and adaptive antitumor immunity","volume":"130","author":"Kim","year":"2017","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.intimp.2025.114450_bb0255","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25031370","article-title":"Mannose ligands for mannose receptor targeting","volume":"25","author":"Paurevic","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"17","key":"10.1016\/j.intimp.2025.114450_bb0260","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00667-21","article-title":"Identification of novel T-cell epitopes on infectious bronchitis virus N protein and development of a multi-epitope vaccine","volume":"95","author":"Qin","year":"2021","journal-title":"J. Virol."},{"key":"10.1016\/j.intimp.2025.114450_bb0265","article-title":"Cytotoxic T lymphocytes and vaccine development 2011","volume":"2011","author":"Xiao","year":"2011","journal-title":"J. Biomed. Biotechnol."},{"issue":"33","key":"10.1016\/j.intimp.2025.114450_bb0270","doi-asserted-by":"crossref","first-page":"16473","DOI":"10.1073\/pnas.1902179116","article-title":"Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination","volume":"116","author":"Boopathy","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2025.114450_bb0275","doi-asserted-by":"crossref","first-page":"1353865","DOI":"10.3389\/fimmu.2024.1353865","article-title":"Complete Freund's adjuvant as a confounding factor in multiple sclerosis research","volume":"15","author":"Lazarevic","year":"2024","journal-title":"Front. Immunol."},{"issue":"39","key":"10.1016\/j.intimp.2025.114450_bb0280","doi-asserted-by":"crossref","first-page":"45585","DOI":"10.1021\/acsami.3c08166","article-title":"Erythrocyte membrane cloaked cytokine functionalized gold nanoparticles create localized controlled inflammation for rapid in vitro wound healing","volume":"15","author":"Dar","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"5","key":"10.1016\/j.intimp.2025.114450_bb0285","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.actbio.2014.01.012","article-title":"Macrophage mannose receptor-specific gene delivery vehicle for macrophage engineering","volume":"10","author":"Ruan","year":"2014","journal-title":"Acta Biomater."},{"issue":"2","key":"10.1016\/j.intimp.2025.114450_bb0290","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.jconrel.2012.01.043","article-title":"PLGA-based nanoparticles: an overview of biomedical applications","volume":"161","author":"Danhier","year":"2012","journal-title":"J. Control. Release"},{"issue":"26","key":"10.1016\/j.intimp.2025.114450_bb0295","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202402445","article-title":"Revolutionizing Neurocare: Biomimetic Nanodelivery Via Cell Membranes","volume":"36","author":"Liao","year":"2024","journal-title":"Adv. Mater."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925004400?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925004400?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:58:23Z","timestamp":1778619503000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925004400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":59,"alternative-id":["S1567576925004400"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114450","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mannose-modified erythrocyte membrane-coated Chuanmingshen violaceum polysaccharide PLGA nanoparticles to improve immune responses in mice","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114450","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114450"}}