{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:13:41Z","timestamp":1778055221208,"version":"3.51.4"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["112\\u20132320-B-182-015"],"award-info":[{"award-number":["112\\u20132320-B-182-015"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["110\\u20132320-B-016-011-MY3"],"award-info":[{"award-number":["110\\u20132320-B-016-011-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["111\\u20132320-B-182-030"],"award-info":[{"award-number":["111\\u20132320-B-182-030"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002836","name":"Chang Gung University","doi-asserted-by":"publisher","award":["CLRPD1J0015"],"award-info":[{"award-number":["CLRPD1J0015"]}],"id":[{"id":"10.13039\/501100002836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.intimp.2025.114643","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T09:16:17Z","timestamp":1744622177000},"page":"114643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Immunomodulatory roles of autophagic flux and IFIT in human ectocervical cells upon Trichomonas vaginalis infection"],"prefix":"10.1016","volume":"155","author":[{"given":"Ching-Chun","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lichieh Julie","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Ming","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsin-Chung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lih-Chyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Yun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Fang","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang-Wen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Ning","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Yang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2025.114643_bb0005","doi-asserted-by":"crossref","unstructured":"Van Der Pol B. Clinical and Laboratory Testing for Trichomonas vaginalis Infection. J. Clin. Microbiol. 2016;54(1):7\u201312. Epub 20151021. doi:https:\/\/doi.org\/10.1128\/JCM.02025-15. PubMed PMID: 26491181; PubMed Central PMCID: PMCPMC4702717.","DOI":"10.1128\/JCM.02025-15"},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0010","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1128\/CMR.11.2.300","article-title":"Clinical and microbiological aspects of trichomonas vaginalis","volume":"11","author":"Petrin","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.intimp.2025.114643_bb0015","doi-asserted-by":"crossref","unstructured":"Fichorova RN. Impact of T. vaginalis infection on innate immune responses and reproductive outcome. J. Reprod. Immunol. 2009;83(1\u20132):185\u20139. Epub 20091021. doi:https:\/\/doi.org\/10.1016\/j.jri.2009.08.007. PubMed PMID: 19850356; PubMed Central PMCID: PMCPMC2788009.","DOI":"10.1016\/j.jri.2009.08.007"},{"issue":"4","key":"10.1016\/j.intimp.2025.114643_bb0020","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s15010-015-0860-0","article-title":"Trichomonas vaginalis: pathogenicity and potential role in human reproductive failure","volume":"44","author":"Mielczarek","year":"2016","journal-title":"Infection"},{"key":"10.1016\/j.intimp.2025.114643_bb0025","doi-asserted-by":"crossref","DOI":"10.1002\/ijgo.14763","article-title":"Trichomonas vaginalis infection is associated with increased risk of cervical carcinogenesis: A systematic review and meta-analysis of 470 000 patients","author":"Hamar","year":"2023","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.intimp.2025.114643_bb0030","article-title":"Association between trichomoniasis and prostate and bladder diseases: a population-based case-control study","volume":"12(1):15358","author":"Yang","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2025.114643_bb0035","series-title":"StatPearls","article-title":"Trichomoniasis","author":"Schumann","year":"2023"},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0040","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/cid\/ciy079","article-title":"Prevalence and correlates of trichomonas vaginalis infection among men and women in the United States","volume":"67","author":"Patel","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.intimp.2025.114643_bb0045","article-title":"Endobiont viruses sensed by the human host - beyond conventional antiparasitic therapy","volume":"7(11):e48418. Epub 20121107","author":"Fichorova","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0050","doi-asserted-by":"crossref","first-page":"A13","DOI":"10.1016\/S0167-5699(05)80005-2","article-title":"The involvement of TNF, IL-1 and IL-6 in the immune response to protozoan parasites","volume":"12","author":"Titus","year":"1991","journal-title":"Immunol. Today"},{"key":"10.1016\/j.intimp.2025.114643_bb0055","article-title":"MCP-1, KC-like and IL-8 as critical mediators of pathogenesis caused by Babesia canis","volume":"13(1):e0190474","author":"Galan","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2025.114643_bb0060","article-title":"IL-6 in inflammation, immunity, and disease","volume":"6(10):a016295","author":"Tanaka","year":"2014","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0065","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0014-5793(92)80909-Z","article-title":"Interleukin-8, a chemotactic and inflammatory cytokine","volume":"307","author":"Baggiolini","year":"1992","journal-title":"FEBS Lett."},{"key":"10.1016\/j.intimp.2025.114643_bb0070","article-title":"IL-6 produced by prostate epithelial cells stimulated with trichomonas vaginalis promotes proliferation of prostate cancer cells by inducing M2 polarization of THP-1-derived macrophages","volume":"14(3):e0008126","author":"Han","year":"2020","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.intimp.2025.114643_bb0075","article-title":"Inflammatory responses during trichomoniasis: the role of toll-like receptors and inflammasomes","volume":"45(8):e13000","author":"Jafarzadeh","year":"2023","journal-title":"Parasite Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0080","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3347\/kjp.2016.54.2.123","article-title":"Inflammatory Responses in a Benign Prostatic Hyperplasia Epithelial Cell Line (BPH-1) Infected with Trichomonas vaginalis","volume":"54","author":"Kim","year":"2016","journal-title":"Korean J Parasitol."},{"issue":"6","key":"10.1016\/j.intimp.2025.114643_bb0085","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a008813","article-title":"Regulation and function of autophagy during cell survival and cell death","volume":"4","author":"Das","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0090","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.immuni.2021.01.018","article-title":"Autophagy in inflammation, infection, and immunometabolism","volume":"54","author":"Deretic","year":"2021","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0095","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.molcel.2014.05.021","article-title":"WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12\u20135-16L1","volume":"55","author":"Dooley","year":"2014","journal-title":"Mol. Cell"},{"issue":"33","key":"10.1016\/j.intimp.2025.114643_bb0100","doi-asserted-by":"crossref","first-page":"24131","DOI":"10.1074\/jbc.M702824200","article-title":"p62\/SQSTM1 binds directly to Atg8\/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy","volume":"282","author":"Pankiv","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2025.114643_bb0105","doi-asserted-by":"crossref","unstructured":"Nishimura T, Tooze SA. Emerging roles of ATG proteins and membrane lipids in autophagosome formation. Cell Discov. 2020;6(1):32. Epub 2020\/06\/09. doi:https:\/\/doi.org\/10.1038\/s41421-020-0161-3. PubMed PMID: 32509328; PubMed Central PMCID: PMCPMC7248066.","DOI":"10.1038\/s41421-020-0161-3"},{"issue":"12","key":"10.1016\/j.intimp.2025.114643_bb0110","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1016\/j.cellsig.2014.08.019","article-title":"The role of PI3K\/AKT\/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration","volume":"26","author":"Heras-Sandoval","year":"2014","journal-title":"Cell. Signal."},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0115","first-page":"1047","article-title":"Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells","volume":"23","author":"Dong","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"11","key":"10.1016\/j.intimp.2025.114643_bb0120","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1080\/15548627.2022.2046448","article-title":"ATF3 -activated accelerating effect of LINC00941\/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1\/HuR in pulmonary fibrosis","volume":"18","author":"Zhang","year":"2022","journal-title":"Autophagy"},{"key":"10.1016\/j.intimp.2025.114643_bb0125","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1146\/annurev-immunol-042617-053253","article-title":"Autophagy and Inflammation","volume":"36","author":"Matsuzawa-Ishimoto","year":"2018","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.intimp.2025.114643_bb0130","doi-asserted-by":"crossref","first-page":"112611","DOI":"10.1016\/j.jep.2020.112611","article-title":"The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K\/Akt\/mTOR pathway","volume":"254","author":"Shao","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2025.114643_bb0135","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13578-020-00464-6","article-title":"Autophagy in the control and pathogenesis of parasitic infections","volume":"10","author":"Ghartey-Kwansah","year":"2020","journal-title":"Cell Biosci."},{"key":"10.1016\/j.intimp.2025.114643_bb0140","doi-asserted-by":"crossref","first-page":"569849","DOI":"10.3389\/fphar.2020.569849","article-title":"Autophagy Modulation in Lymphocytes From COVID-19 Patients: New Therapeutic Target in SARS-COV-2 Infection","volume":"11","author":"Vomero","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"25","key":"10.1016\/j.intimp.2025.114643_bb0145","doi-asserted-by":"crossref","first-page":"40817","DOI":"10.18632\/oncotarget.17256","article-title":"Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFkappaB pathways in autophagy- and p62-dependent manners","volume":"8","author":"Ko","year":"2017","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0150","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1550-7408.1995.tb01579.x","article-title":"YI-S, a casein-free medium for axenic cultivation of Entamoeba histolytica, related Entamoeba, Giardia intestinalis and trichomonas vaginalis","volume":"42","author":"Diamond","year":"1995","journal-title":"J. Eukaryot. Microbiol."},{"issue":"4","key":"10.1016\/j.intimp.2025.114643_bb0155","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1095\/biolreprod57.4.847","article-title":"Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins","volume":"57","author":"Fichorova","year":"1997","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/cancers15010177","article-title":"Extracellular Vesicle Membrane Protein Profiling and Targeted Mass Spectrometry Unveil CD59 and Tetraspanin 9 as Novel Plasma Biomarkers for Detection of Colorectal Cancer","volume":"15","author":"Dash","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"7","key":"10.1016\/j.intimp.2025.114643_bb0165","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1074\/mcp.M115.057026","article-title":"Identification and Characterization of Potential Biomarkers by Quantitative Tissue Proteomics of Primary Lung Adenocarcinoma","volume":"15","author":"Hsu","year":"2016","journal-title":"Mol. Cell. Proteomics"},{"issue":"43","key":"10.1016\/j.intimp.2025.114643_bb0170","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2025.114643_bb0175","doi-asserted-by":"crossref","unstructured":"Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 2000;25(1):25\u20139. Epub 2000\/05\/10. doi:https:\/\/doi.org\/10.1038\/75556. PubMed PMID: 10802651; PubMed Central PMCID: PMCPMC3037419.","DOI":"10.1038\/75556"},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0180","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0185","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1074\/jbc.M807890200","article-title":"Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth","volume":"284","author":"Wang","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"Pt 12","key":"10.1016\/j.intimp.2025.114643_bb0190","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1107\/S0907444913022385","article-title":"The TLR signalling adaptor TRIF\/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins","volume":"69","author":"Ullah","year":"2013","journal-title":"Acta Crystallogr D Biol Crystallogr."},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0195","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3347\/PHD.22160","article-title":"Inflammatory response to Trichomonas vaginalis in the pathogenesis of prostatitis and benign prostatic hyperplasia","volume":"61","author":"Han","year":"2023","journal-title":"Parasites Hosts Dis."},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0200","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1365-3024.2011.01338.x","article-title":"Involvement of mast cells in inflammation induced by trichomonas vaginalis via crosstalk with vaginal epithelial cells","volume":"34","author":"Han","year":"2012","journal-title":"Parasite Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2025.114643_bb0205","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1158\/2159-8290.CD-21-1115","article-title":"A therapeutically actionable Protumoral Axis of cytokines involving IL-8, TNFalpha, and IL-1beta","volume":"12","author":"Olivera","year":"2022","journal-title":"Cancer Discov."},{"issue":"5","key":"10.1016\/j.intimp.2025.114643_bb0210","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1084\/jem.171.5.1797","article-title":"Neutrophil-activating properties of the melanoma growth-stimulatory activity","volume":"171","author":"Moser","year":"1990","journal-title":"J. Exp. Med."},{"issue":"20","key":"10.1016\/j.intimp.2025.114643_bb0215","doi-asserted-by":"crossref","first-page":"7188","DOI":"10.1073\/pnas.84.20.7188","article-title":"Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells","volume":"84","author":"Anisowicz","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0220","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/jcb.240360209","article-title":"Melanoma growth stimulatory activity: isolation from human melanoma tumors and characterization of tissue distribution","volume":"36","author":"Richmond","year":"1988","journal-title":"J. Cell. Biochem."},{"issue":"7","key":"10.1016\/j.intimp.2025.114643_bb0225","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.4049\/jimmunol.168.7.3195","article-title":"IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking","volume":"168","author":"Dufour","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2025.114643_bb0230","article-title":"Dynamic immune markers predict HIV acquisition and augment associations with sociobehavioral factors for HIV exposure","volume":"25(12):105632","author":"Bender Ignacio","year":"2022","journal-title":"iScience"},{"issue":"5","key":"10.1016\/j.intimp.2025.114643_bb0235","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/jmv.24026","article-title":"Interferon-inducible protein 10 (IP-10) is associated with viremia of early HIV-1 infection in Korean patients","volume":"87","author":"Lee","year":"2015","journal-title":"J. Med. Virol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0240","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1080\/15548627.2022.2084686","article-title":"The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication","volume":"19","author":"Hou","year":"2023","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0245","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41580-022-00542-2","article-title":"The mechanisms and roles of selective autophagy in mammals","volume":"24","author":"Vargas","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.intimp.2025.114643_bb0250","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1159\/000504322","article-title":"Rapamycin Treatment Reduces Acute Myocarditis Induced by Trypanosoma cruzi Infection","volume":"12","author":"Duque","year":"2020","journal-title":"J Innate Immun."},{"key":"10.1016\/j.intimp.2025.114643_bb0255","article-title":"Endosymbiotic RNA virus inhibits Leishmania-induced caspase-11 activation","volume":"24(1):102004. Epub 20201229","author":"de Carvalho","year":"2021","journal-title":"iScience"},{"issue":"23","key":"10.1016\/j.intimp.2025.114643_bb0260","doi-asserted-by":"crossref","DOI":"10.3390\/cells11233895","article-title":"Impaired Autophagy Causes Severe Corneal Neovascularization","volume":"11","author":"Yi","year":"2022","journal-title":"Cells"},{"issue":"16","key":"10.1016\/j.intimp.2025.114643_bb0265","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2022643118","article-title":"SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes","volume":"118","author":"Li","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2025.114643_bb0270","doi-asserted-by":"crossref","first-page":"110161","DOI":"10.1016\/j.intimp.2023.110161","article-title":"TLR3 recognition of viral double-stranded RNA in human dental pulp cells is important for the innate immunity","volume":"119","author":"Ha","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2025.114643_bb0275","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.3389\/fphar.2018.01368","article-title":"IFN-beta Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation","volume":"9","author":"Bolivar","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.114643_bb0280","doi-asserted-by":"crossref","first-page":"828439","DOI":"10.3389\/fcimb.2022.828439","article-title":"Increased Interferon-Induced Protein With Tetracopeptides (IFITs) Reduces Mycobacterial Growth","volume":"12","author":"Madhvi","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114643_bb0285","doi-asserted-by":"crossref","DOI":"10.3390\/v15020342","article-title":"How Different Pathologies Are Affected by IFIT Expression","volume":"15","author":"Franco","year":"2023","journal-title":"Viruses"},{"issue":"1","key":"10.1016\/j.intimp.2025.114643_bb0290","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000511915","article-title":"IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist","volume":"46","author":"Imaizumi","year":"2021","journal-title":"Kidney Blood Press. Res."},{"key":"10.1016\/j.intimp.2025.114643_bb0295","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3389\/fmolb.2019.00148","article-title":"Emerging Functions of Human IFIT Proteins in Cancer","volume":"6","author":"Pidugu","year":"2019","journal-title":"Front. Mol. Biosci."},{"issue":"3","key":"10.1016\/j.intimp.2025.114643_bb0300","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1093\/ibd\/izy332","article-title":"Identification of new potential therapies for colitis amelioration using an appendicitis-appendectomy model","volume":"25","author":"Cheluvappa","year":"2019","journal-title":"Inflamm. Bowel Dis."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925006332?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925006332?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T07:26:36Z","timestamp":1778052396000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925006332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":60,"alternative-id":["S1567576925006332"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114643","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunomodulatory roles of autophagic flux and IFIT in human ectocervical cells upon Trichomonas vaginalis infection","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114643","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114643"}}