{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:58:48Z","timestamp":1777575528883,"version":"3.51.4"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82090021"],"award-info":[{"award-number":["82090021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82070732"],"award-info":[{"award-number":["82070732"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82325009"],"award-info":[{"award-number":["82325009"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2019-I2M-5-046"],"award-info":[{"award-number":["2019-I2M-5-046"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["Z221100007922041"],"award-info":[{"award-number":["Z221100007922041"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"CAMS Innovation Fund for Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017415","name":"Peking University First Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017415","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.intimp.2025.114795","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T07:46:51Z","timestamp":1746863211000},"page":"114795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The efficacy and safety of rituximab in adult patients with steroid-dependent or frequent relapsing nephrotic syndrome: A retrospective study"],"prefix":"10.1016","volume":"158","author":[{"given":"Jing","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-miao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-qiang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu-yang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-hui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2025.114795_bb0005","first-page":"S1","article-title":"Improving global outcomes (KDIGO) glomerulonephritis work group. KDIGO clinical practice guideline for glomerulonephritis","volume":"100","author":"Disease","year":"2021","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.intimp.2025.114795_bb0010","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1056\/NEJMoa0909169","article-title":"Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis","volume":"363","author":"Jones","year":"2010","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0015","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1056\/NEJMoa1814427","article-title":"Rituximab or cyclosporine in the treatment of membranous nephropathy","volume":"381","author":"Fervenza","year":"2019","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0020","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1681\/ASN.2021060794","article-title":"Discovery of autoantibodies targeting Nephrin in minimal change Disease supports a novel autoimmune etiology","volume":"33","author":"Watts","year":"2022","journal-title":"J. Am. Soc. Nephrol."},{"issue":"5","key":"10.1016\/j.intimp.2025.114795_bb0025","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1056\/NEJMoa2314471","article-title":"Autoantibodies targeting Nephrin in Podocytopathies","volume":"391","author":"Hengel","year":"2024","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.intimp.2025.114795_bb0030","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1007\/s00467-004-1434-z","article-title":"Change of the course of steroid-dependent nephrotic syndrome after rituximab therapy","volume":"19","author":"Benz","year":"2004","journal-title":"Pediatr. Nephrol."},{"issue":"9950","key":"10.1016\/j.intimp.2025.114795_bb0035","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0140-6736(14)60541-9","volume":"384","author":"Iijima","year":"2014","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.intimp.2025.114795_bb0040","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1681\/ASN.2013030251","article-title":"Rituximab in nephrotic syndrome of steroid-dependent or frequently relapsing minimal change Disease or focal segmental glomerulosclerosis (NEMO) study group. Rituximab in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome","volume":"25","author":"Ruggenenti","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"issue":"8","key":"10.1016\/j.intimp.2025.114795_bb0045","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/jamapediatrics.2018.1323","article-title":"Efficacy of rituximab vs tacrolimus in pediatric corticosteroid-dependent nephrotic syndrome: a randomized clinical trial","volume":"172","author":"Basu","year":"2018","journal-title":"JAMA Pediatr."},{"issue":"8","key":"10.1016\/j.intimp.2025.114795_bb0050","article-title":"Rituximab therapy for primary membranous nephropathy in a Chinese cohort","volume":"20","author":"Gao","year":"2021","journal-title":"Front. Med. (Lausanne)."},{"key":"10.1016\/j.intimp.2025.114795_bb0055","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1093\/ndt\/gfx295","article-title":"Rituximab for non-responsive idiopathic membranous nephropathy in a Chinese cohort","volume":"33","author":"Wang","year":"2018","journal-title":"Nephrol. Dial. Transplant."},{"issue":"11","key":"10.1016\/j.intimp.2025.114795_bb0060","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1093\/ndt\/gfu209","article-title":"Rituximab for minimal-change nephrotic syndrome in adulthood: predictive factors for response, long-term outcomes and tolerance","volume":"29","author":"Guitard","year":"2014","journal-title":"Nephrol. Dial. Transplant."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0065","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s12882-020-01797-7","article-title":"Rituximab therapy for focal segmental glomerulosclerosis and minimal change disease in adults: a systematic review and meta-analysis","volume":"21","author":"Hansrivijit","year":"2020","journal-title":"BMC Nephrol."},{"issue":"2","key":"10.1016\/j.intimp.2025.114795_bb0070","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/ckj\/sfy067","article-title":"Continuous B-cell depletion in frequently relapsing, steroid-dependent and steroid-resistant nephrotic syndrome","volume":"12","author":"Cortazar","year":"2018","journal-title":"Clin. Kidney J."},{"issue":"5","key":"10.1016\/j.intimp.2025.114795_bb0075","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1093\/ndt\/gfs515","article-title":"Effect of single-dose rituximab on steroid-dependent minimal-change nephrotic syndrome in adults","volume":"28","author":"Takei","year":"2013","journal-title":"Nephrol. Dial. Transplant."},{"issue":"4","key":"10.1016\/j.intimp.2025.114795_bb0080","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/ndt\/gft312","article-title":"Rituximab for minimal change disease in adults: long-term follow-up","volume":"29","author":"Bruchfeld","year":"2014","journal-title":"Nephrol. Dial. Transplant."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0085","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1186\/s12882-021-02437-4","article-title":"Extended infusion of rituximab combined with steroids is effective in inducing remission and reducing relapse in adult minimal change disease","volume":"22","author":"Liu","year":"2021","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.intimp.2025.114795_bb0090","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaut.2017.10.006","article-title":"NEPHRUTIX: a randomized, double-blind, placebo vs rituximab-controlled trial assessing T-cell subset changes in minimal change nephrotic syndrome","volume":"88","author":"Boumediene","year":"2018","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.intimp.2025.114795_bb0095","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10157-018-1630-y","article-title":"Therapeutic efficacy of rituximab for the management of adult-onset steroid-dependent nephrotic syndrome: a retrospective study","volume":"23","author":"Katsuno","year":"2019","journal-title":"Clin. Exp. Nephrol."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0100","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s10157-017-1415-8","article-title":"Relapse of nephrotic syndrome during post-rituximab peripheral blood B-lymphocyte depletion","volume":"22","author":"Sato","year":"2018","journal-title":"Clin. Exp. Nephrol."},{"key":"10.1016\/j.intimp.2025.114795_bb0105","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7651024","article-title":"Circulating (CD3(\u2212)CD19(+)CD20(\u2212)IgD(\u2212)CD27(high)CD38(high)) Plasmablasts: a promising cellular biomarker for immune activity for anti-PLA2R1 related membranous nephropathy?","volume":"2016","author":"Pozdzik","year":"2016","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.intimp.2025.114795_bb0110","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000535010","article-title":"Efficacy of rituximab for minimal change Disease and focal segmental glomerulosclerosis with frequently relapsing or steroid-dependent nephrotic syndrome in adults: a Chinese multicenter retrospective study","volume":"55","author":"Lan","year":"2024","journal-title":"Am. J. Nephrol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925007854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925007854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T21:52:29Z","timestamp":1762552349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925007854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":22,"alternative-id":["S1567576925007854"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114795","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The efficacy and safety of rituximab in adult patients with steroid-dependent or frequent relapsing nephrotic syndrome: A retrospective study","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.114795","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114795"}}