{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:54:05Z","timestamp":1791665645075,"version":"4.3.4"},"reference-count":276,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.intimp.2025.115015","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T07:53:26Z","timestamp":1749196406000},"page":"115015","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Neuroinflammation to neurodegeneration: Boulevard of broken nerves"],"prefix":"10.1016","volume":"161","author":[{"given":"Ali","family":"Attiq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheryar","family":"Afzal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemavalli","family":"Raman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqas","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2025.115015_bb0005","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2019.01008","article-title":"Neuroinflammation as a common feature of neurodegenerative disorders","volume":"10","author":"Guzman-Martinez","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0010","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/1756-3305-7-372","article-title":"Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis","volume":"7","author":"Zhang","year":"2014","journal-title":"Parasit. Vectors"},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.103108","article-title":"Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods","volume":"24","author":"Sowers","year":"2021","journal-title":"Iscience"},{"key":"10.1016\/j.intimp.2025.115015_bb0020","series-title":"Neuroplasticity in the Pathology of Neurodegenerative Diseases","author":"Dorszewska","year":"2020"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0025","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/01.STR.32.5.1208","article-title":"Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain","volume":"32","author":"Ito","year":"2001","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0030","article-title":"AIF1: function and connection with inflammatory diseases","volume":"12","author":"De Leon-Oliva","year":"2023","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.intimp.2025.115015_bb0035","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1007\/s12035-014-8697-6","article-title":"Histamine induces upregulated expression of histamine receptors and increases release of inflammatory mediators from microglia","volume":"49","author":"Dong","year":"2014","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0040","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/jnc.12361","article-title":"Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells","volume":"127","author":"Park","year":"2013","journal-title":"J. Neurochem."},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb0045","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a028035","article-title":"Pathology of neurodegenerative diseases","volume":"9","author":"Dugger","year":"2017","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.intimp.2025.115015_bb0050","series-title":"Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease, Springer Science & Business Media","author":"Harris","year":"2012"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0055","doi-asserted-by":"crossref","first-page":"91","DOI":"10.31887\/DCNS.2016.18.1\/pnopoulos","article-title":"Huntington disease: a single-gene degenerative disorder of the striatum","volume":"18","author":"Nopoulos","year":"2016","journal-title":"Dialogues Clin. Neurosci."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0060","first-page":"289","article-title":"Preclinical progression of neurodegenerative diseases","volume":"80","author":"Katsuno","year":"2018","journal-title":"Nagoya J. Med. Sci."},{"key":"10.1016\/j.intimp.2025.115015_bb0065","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/258582","article-title":"Influence of inflammation on poststroke plasticity","volume":"2013","author":"Liguz-Lecznar","year":"2013","journal-title":"Neural Plast."},{"key":"10.1016\/j.intimp.2025.115015_bb0070","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3389\/fncel.2015.00040","article-title":"Inflammation and neuronal plasticity: a link between childhood trauma and depression pathogenesis","volume":"9","author":"Cattaneo","year":"2015","journal-title":"Front. Cell. Neurosci."},{"issue":"24","key":"10.1016\/j.intimp.2025.115015_bb0075","doi-asserted-by":"crossref","first-page":"9854","DOI":"10.1073\/pnas.0903546106","article-title":"Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity","volume":"106","author":"Stanika","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.intimp.2025.115015_bb0080","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jneuroim.2017.03.005","article-title":"N-methyl-d-aspartate receptor-mediated calcium overload and endoplasmic reticulum stress are involved in interleukin-1beta-induced neuronal apoptosis in rat hippocampus","volume":"307","author":"Dong","year":"2017","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.intimp.2025.115015_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101311","article-title":"Region-specific vulnerability in neurodegeneration: lessons from normal ageing","volume":"67","author":"Pandya","year":"2021","journal-title":"Ageing Res. Rev."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0090","first-page":"423","article-title":"Yoga-and meditation-based lifestyle intervention increases neuroplasticity and reduces severity of major depressive disorder: a randomized controlled trial","volume":"36","author":"Tolahunase","year":"2018","journal-title":"Restor. Neurol. Neurosci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0095","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s40035-020-00221-2","article-title":"Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes","volume":"9","author":"Kwon","year":"2020","journal-title":"Translational Neurodegeneration"},{"key":"10.1016\/j.intimp.2025.115015_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2021.111473","article-title":"Role of glial cells in the generation of sex differences in neurodegenerative diseases and brain aging","volume":"196","author":"Chowen","year":"2021","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.intimp.2025.115015_bb0105","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.718324","article-title":"Modulation of glial function in health, aging, and neurodegenerative disease","volume":"15","author":"Hanslik","year":"2021","journal-title":"Front. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0110","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/s41392-022-00872-9","article-title":"Targeting polarized phenotype of microglia via IL6\/JAK2\/STAT3 signaling to reduce NSCLC brain metastasis","volume":"7","author":"Jin","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb0115","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1002\/glia.23172","article-title":"Interferon-\u03b2 regulates the production of IL-10 by toll-like receptor-activated microglia","volume":"65","author":"Lobo-Silva","year":"2017","journal-title":"Glia"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0120","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.2353\/ajpath.2006.050924","article-title":"Gangliosides trigger inflammatory responses via TLR4 in brain glia","volume":"168","author":"Jou","year":"2006","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.intimp.2025.115015_bb0125","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00259-010-1612-0","article-title":"In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer's disease","volume":"38","author":"Yokokura","year":"2011","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0130","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1523\/JNEUROSCI.21-04-01179.2001","article-title":"\u0392-Amyloid stimulation of microglia and monocytes results in TNF\u03b1-dependent expression of inducible nitric oxide synthase and neuronal apoptosis","volume":"21","author":"Combs","year":"2001","journal-title":"J. Neurosci."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0135","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.3390\/antiox10121917","article-title":"ROS-induced mtDNA release: the emerging messenger for communication between neurons and innate immune cells during neurodegenerative disorder progression","volume":"10","author":"Zhao","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.intimp.2025.115015_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2019.104517","article-title":"Microglia-mediated synaptic pruning is impaired in sleep-deprived adolescent mice","volume":"130","author":"Tuan","year":"2019","journal-title":"Neurobiol. Dis."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0145","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/s41593-018-0334-7","article-title":"Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning","volume":"22","author":"Sellgren","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-020-01898-y","article-title":"Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration","volume":"17","author":"Das","year":"2020","journal-title":"J. Neuroinflammation"},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0155","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/glia.24494","article-title":"Proteomic profiling of interferon-responsive reactive astrocytes in rodent and human","volume":"72","author":"Prakash","year":"2024","journal-title":"Glia"},{"key":"10.1016\/j.intimp.2025.115015_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2020.105225","article-title":"Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration","volume":"149","author":"Noori","year":"2021","journal-title":"Neurobiol. Dis."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0165","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/brain\/awr032","article-title":"Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development","volume":"134","author":"Zurolo","year":"2011","journal-title":"Brain"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0170","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/jnc.12790","article-title":"S100B protein activates a RAGE-dependent autocrine loop in astrocytes: implications for its role in the propagation of reactive gliosis","volume":"131","author":"Villarreal","year":"2014","journal-title":"J. Neurochem."},{"issue":"18","key":"10.1016\/j.intimp.2025.115015_bb0175","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.1523\/JNEUROSCI.5480-05.2006","article-title":"Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide","volume":"26","author":"Brahmachari","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0180","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s11481-014-9553-1","article-title":"IL-17A induces MIP-1\u03b1 expression in primary astrocytes via Src\/MAPK\/PI3K\/NF-kB pathways: implications for multiple sclerosis","volume":"9","author":"Yi","year":"2014","journal-title":"J. NeuroImmune Pharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0185","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.neuroscience.2013.07.061","article-title":"IL-1\u03b2 induces GFAP expression in vitro and in vivo and protects neurons from traumatic injury-associated apoptosis in rat brain striatum via NF\u03baB\/Ca2+\u2212calmodulin\/ERK mitogen-activated protein kinase signaling pathway","volume":"252","author":"Sticozzi","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.intimp.2025.115015_bb0190","doi-asserted-by":"crossref","first-page":"4245821","DOI":"10.1155\/2020\/4245821","article-title":"Neuroplasticity in the pathology of neurodegenerative diseases","volume":"2020","author":"Dorszewska","year":"2020","journal-title":"Neural Plast."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0195","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.bbr.2008.02.015","article-title":"Training-induced structural changes in the adult human brain","volume":"192","author":"Draganski","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0200","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s40035-020-00224-z","article-title":"Targeting neuroplasticity in patients with neurodegenerative diseases using brain stimulation techniques","volume":"9","author":"Yuan","year":"2020","journal-title":"Translational Neurodegeneration"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0205","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/TGR.0b013e31821e588e","article-title":"Plasticity in early Alzheimer's disease: An opportunity for intervention","volume":"27","author":"Hill","year":"2011","journal-title":"Top Geriatr Rehabil"},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0210","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a005710","article-title":"NMDA receptor-dependent long-term potentiation and long-term depression (LTP\/LTD)","volume":"4","author":"L\u00fcscher","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"5412","key":"10.1016\/j.intimp.2025.115015_bb0215","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1126\/science.284.5412.336","article-title":"NMDA receptor-mediated K<sup>+<\/sup> efflux and neuronal apoptosis","volume":"284","author":"Yu","year":"1999","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb0220","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1523\/JNEUROSCI.0116-07.2007","article-title":"NMDA receptor subunits have differential roles in mediating Excitotoxic neuronal death both <em>in vitro<\/em> and <em>in vivo<\/em>","volume":"27","author":"Liu","year":"2007","journal-title":"J. Neurosci."},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb0225","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1002\/alz.12088","article-title":"GABAergic dysfunction in excitatory and inhibitory (E\/I) imbalance drives the pathogenesis of Alzheimer's disease","volume":"16","author":"Bi","year":"2020","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.intimp.2025.115015_bb0230","doi-asserted-by":"crossref","DOI":"10.1177\/1744806919847366","article-title":"The etiological contribution of GABAergic plasticity to the pathogenesis of neuropathic pain","volume":"15","author":"Li","year":"2019","journal-title":"Mol. Pain"},{"key":"10.1016\/j.intimp.2025.115015_bb0235","first-page":"91","article-title":"GABAergic synapses: their plasticity and role in sensory cortex","volume":"8","author":"Griffen","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0240","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnsyn.2012.00005","article-title":"Short-term ionic plasticity at GABAergic synapses","volume":"4","author":"Raimondo","year":"2012","journal-title":"Frontiers in synaptic neuroscience"},{"key":"10.1016\/j.intimp.2025.115015_bb0245","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3389\/fncel.2014.00167","article-title":"GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer's disease","volume":"8","author":"Nava-Mesa","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0250","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3389\/fncel.2019.00077","article-title":"Alterations in GABAA-receptor trafficking and synaptic dysfunction in brain disorders","volume":"13","author":"Mele","year":"2019","journal-title":"Front. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105728","article-title":"Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF\/TrkB signaling alterations","volume":"26","author":"Sgritta","year":"2023","journal-title":"Iscience"},{"key":"10.1016\/j.intimp.2025.115015_bb0260","doi-asserted-by":"crossref","DOI":"10.3389\/fnsyn.2022.911020","article-title":"The Yin and Yang of GABAergic and glutamatergic synaptic plasticity: opposites in balance by Crosstalking mechanisms","volume":"14","author":"Chapman","year":"2022","journal-title":"Front Synaptic Neurosci"},{"key":"10.1016\/j.intimp.2025.115015_bb0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-6606-2-35","article-title":"Abnormalities in brain structure and behavior in GSK-3alpha mutant mice","volume":"2","author":"Kaidanovich-Beilin","year":"2009","journal-title":"Mol. Brain"},{"key":"10.1016\/j.intimp.2025.115015_bb0270","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3389\/fncel.2017.00190","article-title":"Effect of neuroinflammation on synaptic organization and function in the developing brain: implications for neurodevelopmental and neurodegenerative disorders","volume":"11","author":"Mottahedin","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0275","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbi.2019.07.003","article-title":"Interplay between inflammation and neural plasticity: both immune activation and suppression impair LTP and BDNF expression","volume":"81","author":"Golia","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.intimp.2025.115015_bb0280","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brainres.2014.08.040","article-title":"Neuroinflammatory changes negatively impact on LTP: a focus on IL-1\u03b2","volume":"1621","author":"Lynch","year":"2015","journal-title":"Brain Res."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0285","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.4103\/1673-5374.371344","article-title":"Cytokines, synaptic plasticity and network dynamics: a matter of balance","volume":"18","author":"Bellingacci","year":"2023","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.intimp.2025.115015_bb0290","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8430123","article-title":"Tumor necrosis factor and interleukin-1\u03b2 modulate synaptic plasticity during neuroinflammation","volume":"2018","author":"Rizzo","year":"2018","journal-title":"Neural Plast."},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb0295","doi-asserted-by":"crossref","first-page":"895","DOI":"10.2174\/1381612820666141027115949","article-title":"Long-term potentiation at spinal C-fiber synapses: a target for pathological pain","volume":"21","author":"Liu","year":"2015","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0300","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/s42003-021-02535-x","article-title":"A role for GABA in the modulation of striatal and hippocampal systems under stress","volume":"4","author":"Dolfen","year":"2021","journal-title":"Communications Biology"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0305","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF00967249","article-title":"Modulation by GABA of neuroplasticity in the central and peripheral nervous system","volume":"18","author":"Wolff","year":"1993","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.intimp.2025.115015_bb0310","doi-asserted-by":"crossref","first-page":"2480689","DOI":"10.1155\/2017\/2480689","article-title":"Neuronal-glial interactions maintain chronic neuropathic pain after spinal cord injury","volume":"2017","author":"Gwak","year":"2017","journal-title":"Neural Plast."},{"key":"10.1016\/j.intimp.2025.115015_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108255","article-title":"The triumvirate of NF-\u03baB, inflammation and cytokine storm in COVID-19","volume":"101","author":"Attiq","year":"2021","journal-title":"Int. Immunopharmacol."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0320","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1038\/npp.2016.50","article-title":"Transcriptomics in interferon-\u03b1-treated patients identifies inflammation-, neuroplasticity- and oxidative stress-related signatures as predictors and correlates of depression","volume":"41","author":"Hepgul","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.intimp.2025.115015_bb0325","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3389\/fncel.2014.00391","article-title":"IFN-\u03b3 differentially modulates memory-related processes under basal and chronic stressor conditions","volume":"8","author":"Litteljohn","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2019.577050","article-title":"Interferon-\u03b3 potentiates GABA(a) receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons","volume":"337","author":"Flood","year":"2019","journal-title":"J. Neuroimmunol."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0335","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2015.194","article-title":"Absence of IFN\u03b3 promotes hippocampal plasticity and enhances cognitive performance","volume":"6","author":"Monteiro","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0340","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.bbi.2010.09.003","article-title":"Interleukin (IL)-1 and IL-6 regulation of neural progenitor cell proliferation with hippocampal injury: differential regulatory pathways in the subgranular zone (SGZ) of the adolescent and mature mouse brain","volume":"25","author":"McPherson","year":"2011","journal-title":"Brain Behav. Immun."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0345","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1177\/1545968319868713","article-title":"Interleukin-6 disrupts synaptic plasticity and impairs tissue damage compensation in multiple sclerosis","volume":"33","author":"Stampanoni Bassi","year":"2019","journal-title":"Neurorehabil. Neural Repair"},{"key":"10.1016\/j.intimp.2025.115015_bb0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-5-45","article-title":"TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease","volume":"5","author":"McCoy","year":"2008","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0355","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.mcn.2012.04.003","article-title":"Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose","volume":"50","author":"Costa","year":"2012","journal-title":"Mol. Cell. Neurosci."},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb0360","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1523\/JNEUROSCI.4580-03.2004","article-title":"Tumor necrosis factor death receptor signaling cascade is required for amyloid-\u03b2 protein-induced neuron death","volume":"24","author":"Li","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-014-0215-2","article-title":"TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain","volume":"11","author":"Wang","year":"2014","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2025.115015_bb0370","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.biopha.2017.04.110","article-title":"The protective effect of propofol against TNF-\u03b1-induced apoptosis was mediated via inhibiting iNOS\/NO production and maintaining intracellular Ca2+ homeostasis in mouse hippocampal HT22 cells","volume":"91","author":"Xu","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"1\u20132","key":"10.1016\/j.intimp.2025.115015_bb0375","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jns.2008.02.021","article-title":"Genetic analysis of tumor necrosis factor-\u03b1 (TNF-\u03b1) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease","volume":"270","author":"Wang","year":"2008","journal-title":"J. Neurol. Sci."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0380","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0092-8674(03)00521-X","article-title":"Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes","volume":"114","author":"Micheau","year":"2003","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0385","doi-asserted-by":"crossref","first-page":"871","DOI":"10.4161\/cc.11.5.19300","article-title":"The role of TRADD in death receptor signaling","volume":"11","author":"Pobezinskaya","year":"2012","journal-title":"Cell Cycle"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0390","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0092-8674(00)80984-8","article-title":"TRADD\u2013TRAF2 and TRADD\u2013FADD interactions define two distinct TNF receptor 1 signal transduction pathways","volume":"84","author":"Hsu","year":"1996","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0395","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1074-7613(00)80535-X","article-title":"The death domain kinase RIP mediates the TNF-induced NF-\u03baB signal","volume":"8","author":"Kelliher","year":"1998","journal-title":"Immunity"},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb0400","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027621","article-title":"A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death","volume":"6","author":"Fischer","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2025.115015_bb0405","doi-asserted-by":"crossref","first-page":"401","DOI":"10.3389\/fcell.2020.00401","article-title":"Selective targeting of TNF receptors as a novel therapeutic approach","volume":"8","author":"Fischer","year":"2020","journal-title":"Frontiers in cell and developmental biology"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0410","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.201708300","article-title":"Counteracting the effects of TNF receptor&#x2010;1 has therapeutic potential in Alzheimer's disease","volume":"10","author":"Steeland","year":"2018","journal-title":"EMBO Mol. Med."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0415","doi-asserted-by":"crossref","first-page":"e1672","DOI":"10.1212\/WNL.0000000000011630","article-title":"Tumor necrosis factor inhibition and Parkinson disease: a Mendelian randomization study","volume":"96","author":"Kang","year":"2021","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0420","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/s12974-021-02200-4","article-title":"Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKK\u03b2 promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice","volume":"18","author":"Papazian","year":"2021","journal-title":"J. Neuroinflammation"},{"issue":"43","key":"10.1016\/j.intimp.2025.115015_bb0425","doi-asserted-by":"crossref","first-page":"12304","DOI":"10.1073\/pnas.1605195113","article-title":"Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration","volume":"113","author":"Dong","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2025.115015_bb0430","doi-asserted-by":"crossref","first-page":"784","DOI":"10.3389\/fimmu.2018.00784","article-title":"Role of TNF-TNF receptor 2 signal in regulatory T cells and its therapeutic implications","volume":"9","author":"Yang","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.115015_bb0435","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.585880","article-title":"Tumor necrosis factor receptors: pleiotropic signaling complexes and their differential effects","volume":"11","author":"Gough","year":"2020","journal-title":"Front. Immunol."},{"issue":"50","key":"10.1016\/j.intimp.2025.115015_bb0440","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2109972118","article-title":"TNF plays a crucial role in inflammation by signaling via T cell TNFR2","volume":"118","author":"Alam","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0445","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3390\/ijms21020387","article-title":"Interleukin-1 beta neutralization attenuates traumatic brain injury-induced microglia activation and neuronal changes in the globus pallidus","volume":"21","author":"Ozen","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2025.115015_bb0450","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2019.103578","article-title":"microRNA-21 negatively regulates NF-\u03baB signaling pathway via targeting IL1R1 in miiuy croaker","volume":"105","author":"Zhang","year":"2020","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.intimp.2025.115015_bb0455","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2022.136533","article-title":"Novel IL1RAP mutation associated with schizophrenia interferes with neuronal growth and related NF-\u03baB signal pathways","volume":"775","author":"Cheng","year":"2022","journal-title":"Neurosci. Lett."},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0460","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1172\/JCI31450","article-title":"Sustained hippocampal IL-1\u03b2 overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology","volume":"117","author":"Shaftel","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0465","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0306-4522(02)00048-9","article-title":"Intracerebroventricular but not intravenous interleukin-1\u03b2 induces widespread vascular-mediated leukocyte infiltration and immune signal mRNA expression followed by brain-wide glial activation","volume":"112","author":"Proescholdt","year":"2002","journal-title":"Neuroscience"},{"key":"10.1016\/j.intimp.2025.115015_bb0470","doi-asserted-by":"crossref","first-page":"5202","DOI":"10.1007\/s12035-018-1428-7","article-title":"Microglia receptors in animal models of traumatic brain injury","volume":"56","author":"Younger","year":"2019","journal-title":"Mol. Neurobiol."},{"issue":"14","key":"10.1016\/j.intimp.2025.115015_bb0475","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.1523\/JNEUROSCI.22-14-06071.2002","article-title":"The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury","volume":"22","author":"Basu","year":"2002","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0480","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.nbd.2007.04.013","article-title":"Overexpression of IL-1\u03b2 by adenoviral-mediated gene transfer in the rat brain causes a prolonged hepatic chemokine response, axonal injury and the suppression of spontaneous behaviour","volume":"27","author":"Campbell","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.intimp.2025.115015_bb0485","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-5-7","article-title":"The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective","volume":"5","author":"Shaftel","year":"2008","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0490","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1006\/exnr.2001.7835","article-title":"The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct?","volume":"173","author":"Emerich","year":"2002","journal-title":"Exp. Neurol."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0495","doi-asserted-by":"crossref","first-page":"6539","DOI":"10.4049\/jimmunol.1100620","article-title":"Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal \u03b2-catenin pathway function in an Alzheimer's disease model","volume":"187","author":"Kitazawa","year":"2011","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0500","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2174\/1389450043345308","article-title":"Cytokines in neuroinflammation and Alzheimer's disease","volume":"5","author":"Cacquevel","year":"2004","journal-title":"Curr. Drug Targets"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0505","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0165-5728(99)00226-X","article-title":"Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?","volume":"103","author":"Licastro","year":"2000","journal-title":"J. Neuroimmunol."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0510","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5483\/BMBRep.2020.53.1.309","article-title":"Peripheral inflammatory biomarkers in Alzheimer's disease: a brief review","volume":"53","author":"Park","year":"2020","journal-title":"BMB Rep."},{"issue":"8","key":"10.1016\/j.intimp.2025.115015_bb0515","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1001\/archneur.57.8.1153","article-title":"Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia","volume":"57","author":"Luterman","year":"2000","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.intimp.2025.115015_bb0520","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.trci.2018.06.014","article-title":"Inflammation as a central mechanism in Alzheimer's disease","volume":"4","author":"Kinney","year":"2018","journal-title":"Alzheimers Dement (N Y)"},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb0525","doi-asserted-by":"crossref","first-page":"5284","DOI":"10.1007\/s12035-022-02909-0","article-title":"p38 MAPK is a major regulator of amyloid Beta-induced IL-6 expression in human microglia","volume":"59","author":"Lin","year":"2022","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0530","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1096\/fj.09-141754","article-title":"Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition","volume":"24","author":"Chakrabarty","year":"2010","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0535","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/s41467-018-03080-8","article-title":"ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity","volume":"9","author":"Massara","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2025.115015_bb0540","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.861931","article-title":"The role of atypical chemokine receptor D6 (ACKR2) in physiological and pathological conditions; friend, foe, or both?","volume":"13","author":"Gowhari Shabgah","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.115015_bb0545","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2016.00224","article-title":"Atypical chemokine receptors and their roles in the resolution of the inflammatory response","volume":"7","author":"Bonecchi","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.115015_bb0550","series-title":"The Role of ACKR2 in Inflammatory Pathologies","author":"Pallas","year":"2015"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0555","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12974-016-0582-y","article-title":"Glial cell activation, recruitment, and survival of B-lineage cells following MCMV brain infection","volume":"13","author":"Lokensgard","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2025.115015_bb0560","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.neuroscience.2019.07.035","article-title":"Chemokines: key molecules that orchestrate communication among neurons, microglia and astrocytes to preserve brain function","volume":"439","author":"Trettel","year":"2020","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0565","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.brainresrev.2004.07.021","article-title":"Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases","volume":"48","author":"Cartier","year":"2005","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.intimp.2025.115015_bb0570","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3389\/fncel.2020.00278","article-title":"Neuromodulation of glial function during neurodegeneration","volume":"14","author":"Stevenson","year":"2020","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0575","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3389\/fnana.2017.00077","article-title":"Microglia polarization with M1\/M2 phenotype changes in rd1 mouse model of retinal degeneration","volume":"11","author":"Zhou","year":"2017","journal-title":"Front. Neuroanat."},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0580","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s00401-016-1605-6","article-title":"Mesenchymal stem cells enhance \u03b1-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder","volume":"132","author":"Park","year":"2016","journal-title":"Acta Neuropathol."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0585","doi-asserted-by":"crossref","first-page":"19855","DOI":"10.18632\/oncotarget.15774","article-title":"M2 microglia promotes neurogenesis and oligodendrogenesis from neural stem\/progenitor cells via the PPAR\u03b3 signaling pathway","volume":"8","author":"Yuan","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.intimp.2025.115015_bb0590","doi-asserted-by":"crossref","first-page":"306","DOI":"10.3389\/fncel.2018.00306","article-title":"Switching of the microglial activation phenotype is a possible treatment for depression disorder","volume":"12","author":"Zhang","year":"2018","journal-title":"Front. Cell. Neurosci."},{"issue":"7638","key":"10.1016\/j.intimp.2025.115015_bb0595","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"issue":"18","key":"10.1016\/j.intimp.2025.115015_bb0600","doi-asserted-by":"crossref","first-page":"6391","DOI":"10.1523\/JNEUROSCI.6221-11.2012","article-title":"Genomic analysis of reactive astrogliosis","volume":"32","author":"Zamanian","year":"2012","journal-title":"J. Neurosci."},{"issue":"36","key":"10.1016\/j.intimp.2025.115015_bb0605","doi-asserted-by":"crossref","first-page":"11929","DOI":"10.1523\/JNEUROSCI.1860-14.2014","article-title":"An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex","volume":"34","author":"Zhang","year":"2014","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0610","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12974-020-01820-6","article-title":"The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study","volume":"17","author":"Ismail","year":"2020","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0615","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s40659-022-00404-3","article-title":"Inflammation context in Alzheimer's disease, a relationship intricate to define","volume":"55","author":"Novoa","year":"2022","journal-title":"Biol. Res."},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0620","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1134\/S002689332104004X","article-title":"Beta amyloid, tau protein, and Neuroinflammation: An attempt to integrate different hypotheses of Alzheimer's disease pathogenesis","volume":"55","author":"Garbuz","year":"2021","journal-title":"Mol. Biol."},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0625","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1073\/pnas.94.6.2642","article-title":"Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease","volume":"94","author":"Kaltschmidt","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0630","doi-asserted-by":"crossref","first-page":"595","DOI":"10.15252\/emmm.201606210","article-title":"The amyloid hypothesis of Alzheimer's disease at 25 years","volume":"8","author":"Selkoe","year":"2016","journal-title":"EMBO Mol. Med."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0635","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24032092","article-title":"Analysis of non-Amyloidogenic mutations in APP supports loss of function hypothesis of Alzheimer's disease","volume":"24","author":"Kim","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb0640","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0080706","article-title":"Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of a\u03b2 and tau","volume":"8","author":"Guo","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.intimp.2025.115015_bb0645","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1523\/JNEUROSCI.2039-21.2021","article-title":"Presenilin is essential for ApoE secretion, a novel role of Presenilin involved in Alzheimer's disease pathogenesis","volume":"42","author":"Islam","year":"2022","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0650","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.freeradbiomed.2006.01.021","article-title":"The various aggregation states of \u03b2-amyloid 1\u201342 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression","volume":"41","author":"Tamagno","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2025.115015_bb0655","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/3087475","article-title":"Neuroinflammatory cytokines induce amyloid beta neurotoxicity through modulating amyloid precursor protein levels\/metabolism","volume":"2018","author":"Alasmari","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.intimp.2025.115015_bb0660","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114120","article-title":"Luteolin and apigenin derived glycosides from Alphonsea elliptica abrogate LPS-induced inflammatory responses in human plasma","volume":"275","author":"Attiq","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0665","doi-asserted-by":"crossref","first-page":"1255727","DOI":"10.3389\/fphar.2023.1255727","article-title":"Trinity of inflammation, innate immune cells and cross-talk of signalling pathways in tumour microenvironment","volume":"14","author":"Attiq","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0670","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s10787-020-00734-2","article-title":"Modulation of inflammatory pathways, medicinal uses and toxicities of Uvaria species: potential role in the prevention and treatment of inflammation","volume":"28","author":"Jalil","year":"2020","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.intimp.2025.115015_bb0675","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jep.2018.10.001","article-title":"The medicinal uses, toxicities and anti-inflammatory activity of Polyalthia species (Annonaceae)","volume":"229","author":"Yao","year":"2019","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0680","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2022.954541","article-title":"NF-\u03baB in neurodegenerative diseases: recent evidence from human genetics","volume":"15","author":"Kaltschmidt","year":"2022","journal-title":"Front. Mol. Neurosci."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0685","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1172\/JCI11916","article-title":"NF-kappaB in neuronal plasticity and neurodegenerative disorders","volume":"107","author":"Mattson","year":"2001","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0690","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.imlet.2015.03.003","article-title":"Lipopolysaccharide directly stimulates Th17 differentiation in vitro modulating phosphorylation of RelB and NF-\u03baB1","volume":"165","author":"Park","year":"2015","journal-title":"Immunol. Lett."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0695","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.4049\/jimmunol.171.4.1816","article-title":"T cell-intrinsic requirement for NF-\u03baB induction in postdifferentiation IFN-\u03b3 production and clonal expansion in a Th1 response","volume":"171","author":"Corn","year":"2003","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0700","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1017\/S0007114511002868","article-title":"Saturated fatty acids activate microglia via toll-like receptor 4\/NF-\u03baB signalling","volume":"107","author":"Wang","year":"2012","journal-title":"Br. J. Nutr."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0705","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1096\/fj.201700826R","article-title":"IKK2\/NF-\u03baB signaling protects neurons after traumatic brain injury","volume":"32","author":"Mettang","year":"2018","journal-title":"FASEB J."},{"issue":"20","key":"10.1016\/j.intimp.2025.115015_bb0710","doi-asserted-by":"crossref","first-page":"8856","DOI":"10.1523\/JNEUROSCI.19-20-08856.1999","article-title":"Lack of the p50 subunit of nuclear factor-\u03baB increases the vulnerability of hippocampal neurons to excitotoxic injury","volume":"19","author":"Yu","year":"1999","journal-title":"J. Neurosci."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0715","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/cr.2008.76","article-title":"BCL-XL regulates TNF-\u03b1-mediated cell death independently of NF-\u03baB","volume":"18","author":"Gozzelino","year":"2008","journal-title":"FLIP and IAPs, Cell research"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0720","doi-asserted-by":"crossref","first-page":"721","DOI":"10.3390\/cells10040721","article-title":"GSK-3 and tau: a key duet in Alzheimer's disease","volume":"10","author":"Sayas","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.intimp.2025.115015_bb0725","article-title":"GSK-3 in neurodegenerative diseases","volume":"2011","author":"Lei","year":"2011","journal-title":"Int. J. Alzheimers Dis."},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb0730","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0203837","article-title":"Cilostazol disrupts TLR-4, Akt\/GSK-3\u03b2\/CREB, and IL-6\/JAK-2\/STAT-3\/SOCS-3 crosstalk in a rat model of Huntington's disease","volume":"13","author":"El-Abhar","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2025.115015_bb0735","doi-asserted-by":"crossref","first-page":"38553","DOI":"10.1038\/srep38553","article-title":"GSK-3\u03b2 controls NF-kappaB activity via IKK\u03b3\/NEMO","volume":"6","author":"Medunjanin","year":"2016","journal-title":"Sci. Rep."},{"issue":"1-2","key":"10.1016\/j.intimp.2025.115015_bb0740","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/emboj\/20.1.27","article-title":"Decreased nuclear \u03b2-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3\u03b2 conditional transgenic mice","volume":"20","author":"Lucas","year":"2001","journal-title":"EMBO J."},{"issue":"27","key":"10.1016\/j.intimp.2025.115015_bb0745","doi-asserted-by":"crossref","first-page":"4631","DOI":"10.2174\/0929867329666220216113517","article-title":"Glycogen synthase kinase 3\u03b2 involvement in neuroinflammation and neurodegenerative diseases","volume":"29","author":"Gianferrara","year":"2022","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.intimp.2025.115015_bb0750","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.phrs.2015.03.010","article-title":"Glycogen synthase kinase-3 beta (GSK-3\u03b2) signaling: implications for Parkinson's disease","volume":"97","author":"Golpich","year":"2015","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0755","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s42269-019-0227-2","article-title":"Toll-like receptors activation, signaling, and targeting: an overview","volume":"43","author":"El-Zayat","year":"2019","journal-title":"Bull. Natl. Res. Cent."},{"key":"10.1016\/j.intimp.2025.115015_bb0760","first-page":"1157023","article-title":"Toll-like receptors (TLRs): structure","volume":"2021","author":"Sameer","year":"2021","journal-title":"Functions, Signaling, and Role of Their Polymorphisms in Colorectal Cancer Susceptibility, Biomed Res Int"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0765","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12974-022-02496-w","article-title":"The role of toll-like receptors and neuroinflammation in Parkinson's disease","volume":"19","author":"Heidari","year":"2022","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2025.115015_bb0770","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2019.105837","article-title":"Eupatilin attenuates the inflammatory response induced by intracerebral hemorrhage through the TLR4\/MyD88 pathway","volume":"76","author":"Fei","year":"2019","journal-title":"Int. Immunopharmacol."},{"issue":"28","key":"10.1016\/j.intimp.2025.115015_bb0775","doi-asserted-by":"crossref","first-page":"11479","DOI":"10.1523\/JNEUROSCI.5566-12.2013","article-title":"TLR7 negatively regulates dendrite outgrowth through the Myd88\u2013c-Fos\u2013IL-6 pathway","volume":"33","author":"Liu","year":"2013","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0780","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.neurobiolaging.2007.08.018","article-title":"Screening of innate immune receptors in neurodegenerative diseases: a similar pattern","volume":"30","author":"Letiembre","year":"2009","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.intimp.2025.115015_bb0785","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13024-015-0003-1","article-title":"Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4-and MyD88-dependent pathway","volume":"10","author":"Rosenberger","year":"2015","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.intimp.2025.115015_bb0790","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2018.00976","article-title":"Raging the war against inflammation with natural products","volume":"9","author":"Attiq","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0795","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s10787-021-00807-w","article-title":"A new prenylated benzoquinone from Cyathocalyx pruniferus abrogates LPS-induced inflammatory responses associated with PGE 2, COX-2 and cytokines biosynthesis in human plasma","volume":"29","author":"Attiq","year":"2021","journal-title":"Inflammopharmacology"},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0800","doi-asserted-by":"crossref","first-page":"5167","DOI":"10.1007\/s12035-020-02087-x","article-title":"The role of brain Cyclooxygenase-2 (Cox-2) beyond Neuroinflammation: neuronal homeostasis in memory and anxiety","volume":"57","author":"L\u00f3pez","year":"2020","journal-title":"Mol. Neurobiol."},{"issue":"6664","key":"10.1016\/j.intimp.2025.115015_bb0805","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/34651","article-title":"Prostaglandins stimulate calcium-dependent glutamate release in astrocytes","volume":"391","author":"Bezzi","year":"1998","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.intimp.2025.115015_bb0810","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.4049\/jimmunol.1601767","article-title":"The endocannabinoid metabolite prostaglandin E(2) (PGE(2))-glycerol inhibits human neutrophil functions: involvement of its hydrolysis into PGE(2) and EP receptors","volume":"198","author":"Turcotte","year":"2017","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb0815","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1172\/JCI83844","article-title":"Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice","volume":"126","author":"Fritz","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0820","doi-asserted-by":"crossref","first-page":"4319","DOI":"10.1523\/JNEUROSCI.5952-11.2012","article-title":"Prostaglandin E<sub>2<\/sub>\u2212mediated attenuation of Mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice","volume":"32","author":"Tanaka","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb0825","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106801","article-title":"COX-2-PGE2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice","volume":"87","author":"Zhu","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0830","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jneuroim.2015.12.003","article-title":"Role of cox-2 mediated neuroinflammation on the neurodegeneration and cognitive impairments in colchicine induced rat model of Alzheimer's disease","volume":"291","author":"Sil","year":"2016","journal-title":"J. Neuroimmunol."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0835","doi-asserted-by":"crossref","first-page":"e1702","DOI":"10.1038\/cddis.2015.69","article-title":"Induction of COX-2-PGE2 synthesis by activation of the MAPK\/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia","volume":"6","author":"Xia","year":"2015","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.intimp.2025.115015_bb0840","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.intimp.2016.12.018","article-title":"Ampelopsin attenuates lipopolysaccharide-induced inflammatory response through the inhibition of the NF-\u03baB and JAK2\/STAT3 signaling pathways in microglia","volume":"44","author":"Weng","year":"2017","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb0845","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3389\/fphar.2018.00462","article-title":"The anti-neuroinflammatory activity of tectorigenin pretreatment via downregulated NF-\u03baB and ERK\/JNK pathways in BV-2 microglial and microglia inactivation in mice with lipopolysaccharide","volume":"9","author":"Lim","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"31","key":"10.1016\/j.intimp.2025.115015_bb0850","doi-asserted-by":"crossref","first-page":"E7408","DOI":"10.1073\/pnas.1802021115","article-title":"Aspirin binds to PPAR\u03b1 to stimulate hippocampal plasticity and protect memory","volume":"115","author":"Patel","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0855","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0304-3940(00)01294-5","article-title":"Ibuprofen protects dopaminergic neurons against glutamate toxicity in vitro","volume":"289","author":"Casper","year":"2000","journal-title":"Neurosci. Lett."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0860","doi-asserted-by":"crossref","first-page":"e463","DOI":"10.1038\/tp.2014.92","article-title":"Peripherally triggered and GSK-3\u03b2-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen","volume":"4","author":"Llorens-Mart\u00edn","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb0865","doi-asserted-by":"crossref","first-page":"296","DOI":"10.3390\/brainsci9110296","article-title":"Clinical role of aspirin in mood disorders: a systematic review","volume":"9","author":"Ng","year":"2019","journal-title":"Brain Sci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0870","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1081\/CRP-120030034","article-title":"Pharmacodynamic and safety study of celecoxib in subjects with probable Alzheimer\u2019s disease","volume":"21","author":"Jhee","year":"2004","journal-title":"Clin. Res. Regul. Aff."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0875","doi-asserted-by":"crossref","first-page":"33","DOI":"10.31138\/mjr.28.1.33","article-title":"In vivo study of pro-inflammatory cytokine changes in serum and synovial fluid during treatment with celecoxib and etoricoxib and correlation with VAS pain change and synovial membrane penetration index in patients with inflammatory arthritis","volume":"28","author":"Theodoridou","year":"2017","journal-title":"Mediterr J Rheumatol"},{"key":"10.1016\/j.intimp.2025.115015_bb0880","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2014.13880","article-title":"Effects of celecoxib on inflammatory markers in bipolar patients undergoing electroconvulsive therapy: a placebo-controlled, double-blind, randomised study","volume":"144","author":"Kargar","year":"2014","journal-title":"Swiss Med. Wkly."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0885","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12103497","article-title":"Celecoxib for mood disorders: a systematic review and Meta-analysis of randomized controlled trials","volume":"12","author":"G\u0119dek","year":"2023","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0890","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/FPC.0b013e32834f94cb","article-title":"Celecoxib pathways: pharmacokinetics and pharmacodynamics","volume":"22","author":"Gong","year":"2012","journal-title":"Pharmacogenet. Genomics"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0895","doi-asserted-by":"crossref","first-page":"44","DOI":"10.21608\/jmals.2021.210630","article-title":"Celecoxib effect on rivastigmine anti-Alzheimer activity against aluminum chloride-induced neurobehavioral deficits as a rat model of Alzheimer's disease; novel perspectives for an old drug","volume":"3","author":"Abdel-Aal","year":"2021","journal-title":"Journal of Medical and Life Science"},{"issue":"63(6)","key":"10.1016\/j.intimp.2025.115015_bb0900","first-page":"786","article-title":"Does diclofenac improve cognition and daily living functioning in Parkinson patients?","volume":"6","author":"Naeem","year":"2015","journal-title":"Int. J. Sci. Eng. Res."},{"issue":"5\u20136","key":"10.1016\/j.intimp.2025.115015_bb0905","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1159\/000485176","article-title":"Etoricoxib and diclofenac might reduce the risk of dementia in patients with osteoarthritis: a nation-wide, population-based retrospective cohort study","volume":"45","author":"Xue","year":"2018","journal-title":"Dement. Geriatr. Cogn. Disord."},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0910","first-page":"4535","article-title":"Improve cognitive impairment using mefenamic acid non-steroidal anti-inflammatory therapy: additional beneficial effect found in a controlled clinical trial for prostate cancer therapy","volume":"13","author":"Melnikov","year":"2021","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.intimp.2025.115015_bb0915","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.bbr.2019.03.009","article-title":"Repeated fluoxetine treatment induces long-lasting neurotrophic changes in the medial prefrontal cortex of adult rats","volume":"365","author":"Song","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb0920","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/0976500X231224528","article-title":"Chronic fluoxetine treatment reverses depressive-like behaviors in mice via enhancing neuroplasticity","volume":"14","author":"Qian","year":"2023","journal-title":"J. Pharmacol. Pharmacother."},{"key":"10.1016\/j.intimp.2025.115015_bb0925","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.107950","article-title":"Effect of sertraline on central serotonin and hippocampal plasticity in pregnant and non-pregnant rats","volume":"166","author":"Pawluski","year":"2020","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0930","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00213-011-2180-0","article-title":"Changes in plasma and platelet BDNF levels induced by S-citalopram in major depression","volume":"216","author":"Serra-Mill\u00e0s","year":"2011","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0935","doi-asserted-by":"crossref","first-page":"6311","DOI":"10.1038\/s41598-019-42775-w","article-title":"5-HTT independent effects of fluoxetine on neuroplasticity","volume":"9","author":"Levy","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0940","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.expneurol.2007.10.015","article-title":"The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6\/2 Huntington's disease mouse model","volume":"210","author":"Peng","year":"2008","journal-title":"Exp. Neurol."},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb0945","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0111665","article-title":"Sertraline reduces IL-1\u03b2 and TNF-\u03b1 mRNA expression and overcomes their rise induced by seizures in the rat hippocampus","volume":"9","author":"Sitges","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2025.115015_bb0950","first-page":"411","article-title":"Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia","volume":"9","author":"Liu","year":"2014","journal-title":"Clin. Interv. Aging"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0955","first-page":"457","article-title":"Neuroplasticity and behavioral effects of fluoxetine after experimental stroke","volume":"35","author":"Sun","year":"2017","journal-title":"Restor. Neurol. Neurosci."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb0960","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.intimp.2013.09.020","article-title":"Sertraline decreases serum level of interleukin-6 (IL-6) in hemodialysis patients with depression: results of a randomized double-blind, placebo-controlled clinical trial","volume":"17","author":"Taraz","year":"2013","journal-title":"Int. Immunopharmacol."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb0965","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1176\/appi.ajp.157.10.1686","article-title":"Randomized, placebo-controlled, double-blind clinical trial of sertraline in the treatment of depression complicating Alzheimer\u2019s disease: initial results from the depression in Alzheimer\u2019s disease study","volume":"157","author":"Lyketsos","year":"2000","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb0970","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1517\/17460441.2016.1160051","article-title":"The preclinical and clinical effects of Vilazodone for the treatment of major depressive disorder","volume":"11","author":"Sahli","year":"2016","journal-title":"Expert Opin. Drug Discov."},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb0975","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1055\/s-0043-107033","article-title":"Comparing the immune-genomic effects of Vilazodone and paroxetine in late-life depression: a pilot study","volume":"50","author":"Eyre","year":"2017","journal-title":"Pharmacopsychiatry"},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb0980","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdiacomp.2020.107723","article-title":"Anti-inflammatory properties of antidiabetic drugs: a \u201cpromised land\u201d in the COVID-19 era?","volume":"34","author":"Katsiki","year":"2020","journal-title":"J. Diabetes Complicat."},{"issue":"7899","key":"10.1016\/j.intimp.2025.115015_bb0985","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/s41586-022-04431-8","article-title":"Low-dose metformin targets the lysosomal AMPK pathway through PEN2","volume":"603","author":"Ma","year":"2022","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb0990","doi-asserted-by":"crossref","first-page":"18721","DOI":"10.1038\/s41598-021-97441-x","article-title":"Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism","volume":"11","author":"Postler","year":"2021","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb0995","doi-asserted-by":"crossref","DOI":"10.1002\/syn.22153","article-title":"Effects of metformin on recognition memory and hippocampal neuroplasticity in rats with metabolic syndrome","volume":"74","author":"Mu\u00f1oz-Arenas","year":"2020","journal-title":"Synapse"},{"key":"10.1016\/j.intimp.2025.115015_bb1000","series-title":"Placebo Controlled Double Blind Crossover Trial of Metformin for Brain Repair in Children Treated with Cranial Radiation for Brain Tumours, University of Toronto (Canada)","author":"Ayoub","year":"2018"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb1005","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/WAD.0000000000000202","article-title":"Effects of the insulin sensitizer metformin in Alzheimer disease: pilot data from a randomized placebo-controlled crossover study","volume":"31","author":"Koenig","year":"2017","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.intimp.2025.115015_bb1010","article-title":"Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease","volume":"101979","author":"Nowell","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.intimp.2025.115015_bb1015","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174703","article-title":"Crosstalk relationship between adiponectin receptors, PPAR-\u03b3 and \u03b1-adrenoceptors in renal vasculature of diabetic WKYs","volume":"917","author":"Afzal","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb1020","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6661181","article-title":"Antioxidant potential of adiponectin and full PPAR-\u03b3 agonist in correcting streptozotocin-induced vascular abnormality in spontaneously hypertensive rats","volume":"2021","author":"Afzal","year":"2021","journal-title":"PPAR Res."},{"key":"10.1016\/j.intimp.2025.115015_bb1025","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3389\/fnmol.2017.00293","article-title":"Rosiglitazone exerts an anti-depressive effect in unpredictable chronic mild-stress-induced depressive mice by maintaining essential neuron autophagy and inhibiting excessive astrocytic apoptosis","volume":"10","author":"Zhao","year":"2017","journal-title":"Front. Mol. Neurosci."},{"issue":"Pt 6","key":"10.1016\/j.intimp.2025.115015_bb1030","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1093\/brain\/awh452","article-title":"Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice","volume":"128","author":"Heneka","year":"2005","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb1035","first-page":"950","article-title":"Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study","volume":"13","author":"Watson","year":"2005","journal-title":"Am. J. Geriatr. Psychiatry"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb1040","first-page":"246","article-title":"Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer\u2019s disease","volume":"6","author":"Risner","year":"2006","journal-title":"Pharm. J."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1045","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.3233\/JAD-190864","article-title":"An exploratory phase IIa study of the PPAR delta\/gamma agonist T3D-959 assessing metabolic and cognitive function in subjects with mild to moderate Alzheimer's disease","volume":"73","author":"Chamberlain","year":"2020","journal-title":"J. Alzheimers Dis."},{"issue":"S9","key":"10.1016\/j.intimp.2025.115015_bb1050","doi-asserted-by":"crossref","DOI":"10.1002\/alz.039922","article-title":"The PIONEER study: a multi-center, randomized, double-blind, placebo-controlled phase 2 trial of the effects of T3D-959 on safety, cognition, function and plasma biomarkers in mild to moderate Alzheimer's disease subjects: rationale and study design","volume":"16","author":"Didsbury","year":"2020","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.intimp.2025.115015_bb1055","article-title":"Hegemony of inflammation in atherosclerosis and coronary artery disease","volume":"176338","author":"Attiq","year":"2024","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb1060","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.2174\/138161212799504803","article-title":"Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials","volume":"18","author":"Antonopoulos","year":"2012","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.intimp.2025.115015_bb1065","first-page":"103","article-title":"Statins and inflammation: new therapeutic opportunities in psychiatry","volume":"10","author":"Kim","year":"2019","journal-title":"Front. Psychol."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb1070","article-title":"Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases","volume":"6","author":"Torrandell-Haro","year":"2020","journal-title":"Alzheimer's & dementia: translational research & clinical interventions"},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb1075","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/pds.3381","article-title":"Statins in the prevention of dementia and Alzheimer's disease: a meta-analysis of observational studies and an assessment of confounding","volume":"22","author":"Wong","year":"2013","journal-title":"Pharmacoepidemiol. Drug Saf."},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb1080","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1089\/neu.2007.0288","article-title":"Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury","volume":"24","author":"Lu","year":"2007","journal-title":"J. Neurotrauma"},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb1085","doi-asserted-by":"crossref","first-page":"3384","DOI":"10.1161\/STROKEAHA.108.544395","article-title":"Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage","volume":"40","author":"Karki","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.intimp.2025.115015_bb1090","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3389\/fnmol.2019.00289","article-title":"Simvastatin restores HDAC1\/2 activity and improves behavioral deficits in Angelman syndrome model mouse","volume":"12","author":"Kumar","year":"2019","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb1095","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/585783","article-title":"Statins promote Long-term recovery after ischemic stroke by reconnecting noradrenergic neuronal circuitry","volume":"2015","author":"Cho","year":"2015","journal-title":"Neural Plast."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb1100","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3171\/jns.2005.103.4.0695","article-title":"Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury","volume":"103","author":"Qu","year":"2005","journal-title":"J. Neurosurg."},{"issue":"4","key":"10.1016\/j.intimp.2025.115015_bb1105","doi-asserted-by":"crossref","DOI":"10.5812\/aapm.117140","article-title":"Evaluation of the effect of atorvastatin administration on the outcomes of patients with traumatic brain injury: a double-blinded randomized clinical trial","volume":"11","author":"Soltani","year":"2021","journal-title":"Anesth Pain Med"},{"key":"10.1016\/j.intimp.2025.115015_bb1110","doi-asserted-by":"crossref","DOI":"10.1016\/j.wnsx.2023.100211","article-title":"The neuroprotective effect of statin in traumatic brain injury: a systematic review","volume":"19","author":"Susanto","year":"2023","journal-title":"World Neurosurg X"},{"issue":"1\u20132","key":"10.1016\/j.intimp.2025.115015_bb1115","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mce.2007.03.007","article-title":"Glucocorticoids in the control of neuroinflammation","volume":"275","author":"Tischner","year":"2007","journal-title":"Mol. Cell. Endocrinol."},{"issue":"10\u221211","key":"10.1016\/j.intimp.2025.115015_bb1120","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.intimp.2004.05.006","article-title":"Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease","volume":"4","author":"Kurkowska-Jastrz\u0119bska","year":"2004","journal-title":"Int. Immunopharmacol."},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb1125","doi-asserted-by":"crossref","first-page":"e1153","DOI":"10.1038\/tp.2017.65","article-title":"Antenatal dexamethasone exposure differentially affects distinct cortical neural progenitor cells and triggers long-term changes in murine cerebral architecture and behavior","volume":"7","author":"Tsiarli","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.intimp.2025.115015_bb1130","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fnmol.2018.00050","article-title":"Topical dexamethasone administration impairs protein synthesis and neuronal regeneration in the olfactory epithelium","volume":"11","author":"Crisafulli","year":"2018","journal-title":"Front. Mol. Neurosci."},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb1135","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1134\/S0006297923050012","article-title":"Glucocorticoids orchestrate adult hippocampal plasticity: growth points and translational aspects","volume":"88","author":"Gulyaeva","year":"2023","journal-title":"Biochem. Mosc."},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb1140","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1177\/1545968319872992","article-title":"Prednisolone pretreatment enhances intermittent hypoxia-induced plasticity in persons with chronic incomplete spinal cord injury","volume":"33","author":"Sandhu","year":"2019","journal-title":"Neurorehabil. Neural Repair"},{"issue":"1\u20133","key":"10.1016\/j.intimp.2025.115015_bb1145","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jad.2006.09.004","article-title":"Effects of chronic prednisone therapy on mood and memory","volume":"99","author":"Brown","year":"2007","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.intimp.2025.115015_bb1150","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1034\/j.1600-0404.2000.00312.x","article-title":"Anti-inflammatory therapy for Alzheimer's disease: implications of the prednisone trial","volume":"102","author":"Aisen","year":"2000","journal-title":"Acta Neurol. Scand."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1155","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1212\/WNL.54.3.588","article-title":"A randomized controlled trial of prednisone in Alzheimer's disease","volume":"54","author":"Aisen","year":"2000","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.intimp.2025.115015_bb1160","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1212\/WNL.62.6.1030","article-title":"DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled trial","volume":"62","author":"Leblhuber","year":"2004","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb1165","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1017\/S1461145711001775","article-title":"Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation","volume":"16","author":"MacDowell","year":"2013","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"1\u20133","key":"10.1016\/j.intimp.2025.115015_bb1170","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.schres.2007.01.019","article-title":"Risperidone significantly inhibits interferon-gamma-induced microglial activation in vitro","volume":"92","author":"Kato","year":"2007","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb1175","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s40268-015-0092-x","article-title":"Comparative pharmacology of risperidone and Paliperidone","volume":"15","author":"Corena-McLeod","year":"2015","journal-title":"Drugs R D"},{"issue":"43","key":"10.1016\/j.intimp.2025.115015_bb1180","doi-asserted-by":"crossref","first-page":"8584","DOI":"10.1523\/JNEUROSCI.1249-19.2019","article-title":"Risperidone ameliorates prefrontal cortex neural atrophy and oxidative\/Nitrosative stress in brain and peripheral blood of rats with neonatal ventral Hippocampus lesion","volume":"39","author":"Tendilla-Beltr\u00e1n","year":"2019","journal-title":"J. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb1185","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3389\/fnbeh.2019.00163","article-title":"Risperidone reverses the downregulation of BDNF in hippocampal neurons and MK801-induced cognitive impairment in rats","volume":"13","author":"Yu","year":"2019","journal-title":"Front. Behav. Neurosci."},{"issue":"12","key":"10.1016\/j.intimp.2025.115015_bb1190","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1002\/gps.1409","article-title":"Risperidone for psychosis of Alzheimer\u2019s disease and mixed dementia: results of a double-blind, placebo-controlled trial","volume":"20","author":"Brodaty","year":"2005","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb1195","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4088\/JCP.v64n0205","article-title":"A randomized placebo-controlled trial of risperidone for the treatment of aggression, agitation, and psychosis of dementia","volume":"64","author":"Brodaty","year":"2003","journal-title":"J. Clin. Psychiatry"},{"issue":"5","key":"10.1016\/j.intimp.2025.115015_bb1200","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/gps.1792","article-title":"The efficacy and safety of risperidone in the treatment of psychosis of Alzheimer\u2019s disease and mixed dementia: a meta-analysis of 4 placebo-controlled clinical trials","volume":"22","author":"Katz","year":"2007","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1205","doi-asserted-by":"crossref","DOI":"10.3390\/ph14030246","article-title":"Behavioral and psychological symptoms in dementia (BPSD) and the use of antipsychotics","volume":"14","author":"Calsolaro","year":"2021","journal-title":"Pharmaceuticals (Basel)"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb1210","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2174\/157015908784533860","article-title":"Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD)","volume":"6","author":"Liperoti","year":"2008","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.intimp.2025.115015_bb1215","article-title":"Reward and immune Systems in Emotion (RISE) prospective longitudinal study: protocol overview of an integrative reward-inflammation model of first onset of major depression in adolescence","volume":"30","author":"Alloy","year":"2023","journal-title":"Brain Behav Immun Health"},{"key":"10.1016\/j.intimp.2025.115015_bb1220","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.bbi.2019.04.014","article-title":"Relationships between neural activation during a reward task and peripheral cytokine levels in youth with diverse psychiatric symptoms","volume":"80","author":"Bradley","year":"2019","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1225","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.yfrne.2012.09.003","article-title":"Cytokine effects on the basal ganglia and dopamine function: the subcortical source of inflammatory malaise","volume":"33","author":"Felger","year":"2012","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.intimp.2025.115015_bb1230","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.01869","article-title":"Critical neurotransmitters in the Neuroimmune network","volume":"11","author":"Hodo","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.115015_bb1235","first-page":"600","article-title":"Why is music therapeutic for neurological disorders?","volume":"112","author":"Brancatisano","year":"2020","journal-title":"The Therapeutic Music Capacities Model, Neurosci Biobehav Rev"},{"issue":"1\u20132","key":"10.1016\/j.intimp.2025.115015_bb1240","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jns.2009.08.028","article-title":"Use of magnetoencephalography (MEG) to study functional brain networks in neurodegenerative disorders","volume":"289","author":"Stam","year":"2010","journal-title":"J. Neurol. Sci."},{"issue":"11","key":"10.1016\/j.intimp.2025.115015_bb1245","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11910-019-1005-0","article-title":"Music therapy and music-based interventions for movement disorders","volume":"19","author":"Devlin","year":"2019","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1250","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1037\/pmu0000139","article-title":"Listening to classical music results in a positive correlation between spatial reasoning and mindfulness","volume":"26","author":"Bell","year":"2016","journal-title":"Psychomusicology: Music, Mind, and Brain"},{"issue":"9","key":"10.1016\/j.intimp.2025.115015_bb1255","doi-asserted-by":"crossref","first-page":"8119","DOI":"10.3390\/ijms24098119","article-title":"Music with different tones affects the development of brain nerves in mice in early life through BDNF and its downstream pathways","volume":"24","author":"Wang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"41","key":"10.1016\/j.intimp.2025.115015_bb1260","doi-asserted-by":"crossref","first-page":"17201","DOI":"10.1073\/pnas.1114241108","article-title":"TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus","volume":"108","author":"Zheng","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.intimp.2025.115015_bb1265","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3389\/fneur.2014.00126","article-title":"Combining non-pharmacological treatments with pharmacotherapies for neurological disorders: a unique interface of the brain, drug-device, and intellectual property","volume":"5","author":"Bulaj","year":"2014","journal-title":"Front. Neurol."},{"key":"10.1016\/j.intimp.2025.115015_bb1270","doi-asserted-by":"crossref","first-page":"1471433","DOI":"10.3389\/fnhum.2025.1471433","article-title":"Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus-amygdala circuit (a review)","volume":"19","author":"Dan","year":"2025","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb1275","doi-asserted-by":"crossref","first-page":"296","DOI":"10.3389\/fnhum.2012.00296","article-title":"Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness","volume":"6","author":"Vago","year":"2012","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.intimp.2025.115015_bb1280","series-title":"UC Berkeley: Public Health & Health Science Division, ULAB","article-title":"A Review of the Relation Between Music and Plasticity","author":"Barsdale","year":"2022"},{"key":"10.1016\/j.intimp.2025.115015_bb1285","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40734-016-0034-y","article-title":"Evolution of visual art with dopaminergic therapy","volume":"3","author":"Walker","year":"2016","journal-title":"J Clin Mov Disord"},{"key":"10.1016\/j.intimp.2025.115015_bb1290","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/B978-0-444-63287-6.00007-5","article-title":"The experience of art: insights from neuroimaging","volume":"204","author":"Nadal","year":"2013","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.intimp.2025.115015_bb1295","doi-asserted-by":"crossref","first-page":"1232357","DOI":"10.3389\/fpsyg.2023.1232357","article-title":"The role of arts engagement in reducing cognitive decline and improving quality of life in healthy older people: a systematic review","volume":"14","author":"Fioranelli","year":"2023","journal-title":"Front. Psychol."},{"key":"10.1016\/j.intimp.2025.115015_bb1300","doi-asserted-by":"crossref","first-page":"1354025","DOI":"10.3389\/fnagi.2024.1354025","article-title":"Mitigating cellular aging and enhancing cognitive functionality: visual arts-mediated cognitive activation therapy in neurocognitive disorders","volume":"16","author":"Campisi","year":"2024","journal-title":"Front. Aging Neurosci."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1305","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cnre.2016.06.011","article-title":"Advances in art therapy for patients with dementia","volume":"3","author":"Wang","year":"2016","journal-title":"Chin. Nurs. Res."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb1310","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2020.165778","article-title":"Exercise, redox system and neurodegenerative diseases","volume":"1866","author":"Quan","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb1315","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3390\/brainsci3010039","article-title":"Exercise benefits brain function: the monoamine connection","volume":"3","author":"Lin","year":"2013","journal-title":"Brain Sci."},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1320","doi-asserted-by":"crossref","first-page":"447","DOI":"10.5114\/aoms.2010.14269","article-title":"Endogenous reward mechanisms and their importance in stress reduction, exercise and the brain","volume":"6","author":"Esch","year":"2010","journal-title":"Arch. Med. Sci."},{"issue":"16","key":"10.1016\/j.intimp.2025.115015_bb1325","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21165895","article-title":"Possible neuroprotective mechanisms of physical exercise in neurodegeneration","volume":"21","author":"Mahalakshmi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb1330","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s40035-023-00341-5","article-title":"Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction","volume":"12","author":"Lu","year":"2023","journal-title":"Transl Neurodegener"},{"issue":"2","key":"10.1016\/j.intimp.2025.115015_bb1335","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/physiologia5020013","article-title":"Exercise-induced neuroplasticity: adaptive mechanisms and preventive potential in neurodegenerative disorders","volume":"5","author":"Mansoor","year":"2025","journal-title":"Physiologia"},{"key":"10.1016\/j.intimp.2025.115015_bb1340","doi-asserted-by":"crossref","first-page":"1337442","DOI":"10.3389\/fphys.2024.1337442","article-title":"Potential molecular mechanism of exercise reversing insulin resistance and improving neurodegenerative diseases","volume":"15","author":"Shen","year":"2024","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.intimp.2025.115015_bb1345","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3109\/10715762.2013.826352","article-title":"The redox-associated adaptive response of brain to physical exercise","volume":"48","author":"Radak","year":"2014","journal-title":"Free Radic. Res."},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb1350","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1073\/pnas.1015950108","article-title":"Exercise training increases size of hippocampus and improves memory","volume":"108","author":"Erickson","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"7","key":"10.1016\/j.intimp.2025.115015_bb1355","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/s41374-019-0232-y","article-title":"The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases","volume":"99","author":"Liu","year":"2019","journal-title":"Lab. Investig."},{"key":"10.1016\/j.intimp.2025.115015_bb1360","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3389\/fpsyg.2013.00031","article-title":"Video games as a means to reduce age-related cognitive decline: attitudes, compliance, and effectiveness","volume":"4","author":"Boot","year":"2013","journal-title":"Front. Psychol."},{"issue":"8","key":"10.1016\/j.intimp.2025.115015_bb1365","article-title":"Biochemical correlates of video game use: from physiology to pathology","volume":"11","author":"Carpita","year":"2021","journal-title":"A Narrative Review, Life (Basel)"},{"issue":"3","key":"10.1016\/j.intimp.2025.115015_bb1370","doi-asserted-by":"crossref","first-page":"319","DOI":"10.31887\/DCNS.2019.21.3\/skuehn","article-title":"Effects of computer gaming on cognition, brain structure, and function: a critical reflection on existing literature","volume":"21","author":"K\u00fchn","year":"2019","journal-title":"Dialogues Clin. Neurosci."},{"issue":"10","key":"10.1016\/j.intimp.2025.115015_bb1375","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3390\/brainsci9100251","article-title":"Does video gaming have impacts on the brain: evidence from a systematic review","volume":"9","author":"Brilliant","year":"2019","journal-title":"Brain Sci."},{"key":"10.1016\/j.intimp.2025.115015_bb1380","doi-asserted-by":"crossref","first-page":"1161850","DOI":"10.3389\/fphar.2023.1161850","article-title":"Revisiting the neuroinflammation hypothesis in Alzheimer's disease: a focus on the druggability of current targets","volume":"14","author":"Wong-Guerra","year":"2023","journal-title":"Front. Pharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925010057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925010057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T20:01:50Z","timestamp":1775764910000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925010057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":276,"alternative-id":["S1567576925010057"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.115015","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroinflammation to neurodegeneration: Boulevard of broken nerves","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.115015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115015"}}