{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T20:55:42Z","timestamp":1784580942058,"version":"3.55.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.intimp.2025.115270","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T01:43:49Z","timestamp":1754358229000},"page":"115270","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Muscone attenuates myocardial infarction by regulating ferroptosis of cardiomyocytes through Nrf2\/system Xc-\/GPX4 signaling pathway"],"prefix":"10.1016","volume":"163","author":[{"given":"Hui","family":"Hui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingliang","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shize","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junying","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.intimp.2025.115270_bb0005","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/j.jacc.2021.03.003","article-title":"The edge of time in acute myocardial infarction","volume":"77","author":"Dauerman","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"issue":"17","key":"10.1016\/j.intimp.2025.115270_bb0010","doi-asserted-by":"crossref","first-page":"e1371","DOI":"10.4244\/EIJ-D-21-00904","article-title":"Antiplatelet therapy after percutaneous coronary intervention","volume":"17","author":"Angiolillo","year":"2022","journal-title":"EuroIntervention"},{"issue":"1","key":"10.1016\/j.intimp.2025.115270_bb0015","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1136\/heartjnl-2017-311155","article-title":"Management of percutaneous coronary intervention complications","volume":"105","author":"Kandan","year":"2019","journal-title":"Heart"},{"issue":"4","key":"10.1016\/j.intimp.2025.115270_bb0020","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/cvr\/cvz301","article-title":"Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction","volume":"116","author":"Konijnenberg","year":"2020","journal-title":"Cardiovasc. Res."},{"issue":"25","key":"10.1016\/j.intimp.2025.115270_bb0025","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.2174\/1381612824666180629162726","article-title":"Microvasculature recovery by angiogenesis after myocardial infarction","volume":"24","author":"Badimon","year":"2018","journal-title":"Curr. Pharm. Des."},{"issue":"2","key":"10.1016\/j.intimp.2025.115270_bb0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/FJC.0000000000001436","article-title":"Cardioprotective and antianginal efficacy of Nicorandil: a comprehensive review","volume":"82","author":"Goel","year":"2023","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"11","key":"10.1016\/j.intimp.2025.115270_bb0035","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1136\/dtb.2003.411186","article-title":"Nicorandil for angina--an update","volume":"41","year":"2003","journal-title":"Drug Ther. Bull."},{"key":"10.1016\/j.intimp.2025.115270_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.175365","article-title":"Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK\/TXNIP\/NLRP3 signaling pathway","volume":"936","author":"Liu","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115270_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2022.110272","article-title":"Nicorandil alleviates cardiac remodeling and dysfunction post -infarction by up-regulating the nucleolin\/autophagy axis","volume":"92","author":"Deng","year":"2022","journal-title":"Cell. Signal."},{"issue":"4","key":"10.1016\/j.intimp.2025.115270_bb0050","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2165\/00003495-200060040-00007","article-title":"An updated review of its use in ischaemic heart disease with emphasis on its cardioprotective effects","volume":"60","author":"Markham","year":"2000","journal-title":"Drugs"},{"issue":"9","key":"10.1016\/j.intimp.2025.115270_bb0055","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.2165\/11592300-000000000-00000","article-title":"Use of nicorandil in cardiovascular disease and its optimization","volume":"71","author":"Horinaka","year":"2011","journal-title":"Drugs"},{"issue":"17","key":"10.1016\/j.intimp.2025.115270_bb0060","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.2165\/00003495-200464170-00012","article-title":"Nicorandil: a review of its use in the management of stable angina pectoris, including high-risk patients","volume":"64","author":"Simpson","year":"2004","journal-title":"Drugs"},{"key":"10.1016\/j.intimp.2025.115270_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105168","article-title":"Traditional Chinese medicine in cardiovascular drug discovery","volume":"160","author":"Leung","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"15","key":"10.1016\/j.intimp.2025.115270_bb0070","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1001\/jama.2024.0617","article-title":"Traditional Chinese medicine compound and clinical outcomes in acute myocardial infarction-reply","volume":"331","author":"Chen","year":"2024","journal-title":"Jama"},{"key":"10.1016\/j.intimp.2025.115270_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114799","article-title":"Chemical compositions and pharmacological activities of natural musk (Moschus) and artificial musk: a review","volume":"284","author":"Lv","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2025.115270_bb0080","doi-asserted-by":"crossref","first-page":"3217395","DOI":"10.1155\/2017\/3217395","article-title":"Prevention of AMI induced ventricular remodeling: inhibitory effects of heart-protecting musk pill on IL-6 and TNF-alpha","volume":"2017","author":"Cen","year":"2017","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"11","key":"10.1016\/j.intimp.2025.115270_bb0085","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23458","article-title":"Muscone attenuates susceptibility to ventricular arrhythmia by inhibiting NLRP3 inflammasome activation in rats after myocardial infarction","volume":"37","author":"Yang","year":"2023","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"12","key":"10.1016\/j.intimp.2025.115270_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2022.166539","article-title":"Muscone suppresses myocardial ischemia damage by regulating PI3K\/Akt signaling pathway","volume":"1868","author":"Zhu","year":"2022","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.intimp.2025.115270_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.116057","article-title":"Ferroptosis in cardiovascular disease","volume":"170","author":"Liu","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2025.115270_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154999","article-title":"EGCG attenuated acute myocardial infarction by inhibiting ferroptosis via miR-450b-5p\/ACSL4 axis","volume":"119","author":"Yu","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.intimp.2025.115270_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113572","article-title":"Dexmedetomidine attenuates myocardial ischemia\/reperfusion-induced ferroptosis via AMPK\/GSK-3\u03b2\/Nrf2 axis","volume":"154","author":"Wang","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"12","key":"10.1016\/j.intimp.2025.115270_bb0110","doi-asserted-by":"crossref","first-page":"5787","DOI":"10.1002\/ptr.7984","article-title":"Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK\/SIRT1\/PGC-1\u03b1 pathway in Schwann cells","volume":"37","author":"Hu","year":"2023","journal-title":"Phytother. Res."},{"key":"10.1016\/j.intimp.2025.115270_bb0115","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.freeradbiomed.2020.02.027","article-title":"Lipid peroxidation and ferroptosis: the role of GSH and GPx4","volume":"152","author":"Ursini","year":"2020","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.intimp.2025.115270_bb0120","article-title":"Nrf2-Keap1 in cardiovascular disease: which is the cart and which the horse?","volume":"39","author":"Dhyani","year":"2024","journal-title":"Physiology (Bethesda)"},{"issue":"1 Pt B","key":"10.1016\/j.intimp.2025.115270_bb0125","article-title":"Natural allies for heart health: Nrf2 activation and cardiovascular disease management","volume":"49","author":"Khan","year":"2024","journal-title":"Curr. Probl. Cardiol."},{"key":"10.1016\/j.intimp.2025.115270_bb0130","article-title":"Maresin1 protect against Ferroptosis-induced liver injury through ROS inhibition and Nrf2\/HO-1\/GPX4 activation","volume":"13","author":"Yang","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115270_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.114048","article-title":"Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6\/p-Nrf2\/GPX4 and SIRT6\/NCOA4\/FTH1 pathways","volume":"157","author":"Mi","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"7","key":"10.1016\/j.intimp.2025.115270_bb0140","doi-asserted-by":"crossref","DOI":"10.3390\/biom11070923","article-title":"Kaempferol ameliorates oxygen-glucose deprivation\/Reoxygenation-induced neuronal Ferroptosis by activating Nrf2\/SLC7A11\/GPX4 Axis","volume":"11","author":"Yuan","year":"2021","journal-title":"Biomolecules"},{"issue":"10","key":"10.1016\/j.intimp.2025.115270_bb0145","doi-asserted-by":"crossref","DOI":"10.4028\/b-wjQRP6","article-title":"VDR activation attenuates renal tubular epithelial cell Ferroptosis by regulating Nrf2\/HO-1 signaling pathway in diabetic nephropathy","volume":"11","author":"Wang","year":"2024","journal-title":"Adv Sci (Weinh)"},{"issue":"2","key":"10.1016\/j.intimp.2025.115270_bb0150","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/s41418-019-0380-z","article-title":"ATF3 promotes erastin-induced ferroptosis by suppressing system Xc","volume":"27","author":"Wang","year":"2020","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.intimp.2025.115270_bb0155","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.freeradbiomed.2025.02.040","article-title":"Nrf2 alleviates acute ischemic stroke induced ferroptosis via regulating xCT\/GPX4 pathway","volume":"231","author":"Ye","year":"2025","journal-title":"Free Radic. Biol. Med."},{"issue":"22","key":"10.1016\/j.intimp.2025.115270_bb0160","doi-asserted-by":"crossref","first-page":"7038","DOI":"10.1111\/febs.16059","article-title":"Signaling pathways and defense mechanisms of ferroptosis","volume":"289","author":"Liu","year":"2022","journal-title":"FEBS J."},{"key":"10.1016\/j.intimp.2025.115270_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115852","article-title":"Qing-Xin-Jie-Yu granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4\/xCT signaling pathway","volume":"301","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1\u20133","key":"10.1016\/j.intimp.2025.115270_bb0170","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ejphar.2011.04.038","article-title":"Pharmacological preconditioning with nicorandil and pioglitazone attenuates myocardial ischemia\/reperfusion injury in rats","volume":"663","author":"Ahmed","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2025.115270_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108599","article-title":"Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs\/mTOR-dependent autophagy pathway","volume":"112","author":"Zhang","year":"2019","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.intimp.2025.115270_bb0180","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s10020-021-00271-w","article-title":"ELAVL1 is transcriptionally activated by FOXC1 and promotes ferroptosis in myocardial ischemia\/reperfusion injury by regulating autophagy","volume":"27","author":"Chen","year":"2021","journal-title":"Mol. Med."},{"issue":"1","key":"10.1016\/j.intimp.2025.115270_bb0185","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13287-020-1563-8","article-title":"Mesenchymal stem cell-derived exosomes ameliorate cardiomyocyte apoptosis in hypoxic conditions through microRNA144 by targeting the PTEN\/AKT pathway","volume":"11","author":"Wen","year":"2020","journal-title":"Stem Cell Res Ther"},{"issue":"5","key":"10.1016\/j.intimp.2025.115270_bb0190","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.intimp.2025.115270_bb0195","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1038\/nprot.2006.179","article-title":"Sulforhodamine B colorimetric assay for cytotoxicity screening","volume":"1","author":"Vichai","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.intimp.2025.115270_bb0200","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/978-1-60761-411-1_4","article-title":"Identification of ROS using oxidized DCFDA and flow-cytometry","volume":"594","author":"Eruslanov","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.intimp.2025.115270_bb0205","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-61779-860-3_5","article-title":"Detection of apoptosis by TUNEL assay","volume":"887","author":"Kyrylkova","year":"2012","journal-title":"Methods Mol. Biol."},{"issue":"7","key":"10.1016\/j.intimp.2025.115270_bb0210","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/s41419-022-05121-z","article-title":"Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction","volume":"13","author":"Henning","year":"2022","journal-title":"Cell Death Dis."},{"issue":"21","key":"10.1016\/j.intimp.2025.115270_bb0215","doi-asserted-by":"crossref","first-page":"12156","DOI":"10.1021\/acs.jafc.4c01134","article-title":"Quercetin inhibits neuronal Pyroptosis and Ferroptosis by modulating microglial M1\/M2 polarization in atherosclerosis","volume":"72","author":"Li","year":"2024","journal-title":"J. Agric. Food Chem."},{"issue":"12","key":"10.1016\/j.intimp.2025.115270_bb0220","doi-asserted-by":"crossref","first-page":"6189","DOI":"10.3390\/cimb44120422","article-title":"Baicalein relieves Ferroptosis-mediated phagocytosis inhibition of macrophages in ovarian endometriosis","volume":"44","author":"Yi","year":"2022","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.intimp.2025.115270_bb0225","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.redox.2017.02.012","article-title":"Mitochondrial composition and function under the control of hypoxia","volume":"12","author":"Fuhrmann","year":"2017","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.intimp.2025.115270_bb0230","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41569-023-00953-4","article-title":"Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction","volume":"21","author":"Galli","year":"2024","journal-title":"Nat. Rev. Cardiol."},{"issue":"2","key":"10.1016\/j.intimp.2025.115270_bb0235","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0753-3322(89)90134-0","article-title":"Thrombolytic therapy and acute myocardial infarction","volume":"43","author":"Vandenbogaerde","year":"1989","journal-title":"Biomed. Pharmacother."},{"issue":"33","key":"10.1016\/j.intimp.2025.115270_bb0240","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1093\/eurheartj\/ehae266","article-title":"Periprocedural myocardial infarction after percutaneous coronary intervention and long-term mortality: a meta-analysis","volume":"45","author":"Paolucci","year":"2024","journal-title":"Eur. Heart J."},{"issue":"11","key":"10.1016\/j.intimp.2025.115270_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e22154","article-title":"Muscone ameliorates myocardial ischemia\u2013reperfusion injury by promoting myocardial glycolysis","volume":"9","author":"Gu","year":"2023","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.intimp.2025.115270_bb0250","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3892\/ijmm.2014.1766","article-title":"Beneficial effects of muscone on cardiac remodeling in a mouse model of myocardial infarction","volume":"34","author":"Wang","year":"2014","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.intimp.2025.115270_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.149628","article-title":"Muscone inhibits the progression of atherosclerotic plaques in mice aorta by inhibiting the NF-\u03baB\/p65 pathway","volume":"702","author":"Li","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2025.115270_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102679","article-title":"TRIM21 deficiency protects against atrial inflammation and remodeling post myocardial infarction by attenuating oxidative stress","volume":"62","author":"Liu","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2025.115270_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117388","article-title":"Buyang Huanwu decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway","volume":"320","author":"Zhang","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.intimp.2025.115270_bb0270","first-page":"263","article-title":"Association of mean platelet volume and red blood cell distribution width with coronary collateral development in stable coronary artery disease","volume":"14","author":"Sincer","year":"2018","journal-title":"Postepy Kardiol Interwencyjnej"},{"issue":"5","key":"10.1016\/j.intimp.2025.115270_bb0275","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1080\/13685538.2019.1643310","article-title":"Differential value of eosinophil count in acute coronary syndrome among elderly patients","volume":"23","author":"Sincer","year":"2020","journal-title":"Aging Male"},{"issue":"12","key":"10.1016\/j.intimp.2025.115270_bb0280","first-page":"4235","article-title":"Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of NF-\u03baB and NLRP3 inflammasome","volume":"10","author":"Du","year":"2018","journal-title":"Am. J. Transl. Res."},{"issue":"3","key":"10.1016\/j.intimp.2025.115270_bb0285","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1152\/physrev.00041.2003","article-title":"Molecular regulation of vascular smooth muscle cell differentiation in development and disease","volume":"84","author":"Owens","year":"2004","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.intimp.2025.115270_bb0290","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1186\/s12964-022-00993-2","article-title":"How vascular smooth muscle cell phenotype switching contributes to vascular disease","volume":"20","author":"Cao","year":"2022","journal-title":"Cell Commun. Signal"},{"issue":"3","key":"10.1016\/j.intimp.2025.115270_bb0295","first-page":"257","article-title":"Double immunofluorescence labeling for CD31 and CD105 as a marker for polyether polyurethane-induced angiogenesis in mice","volume":"34","author":"Figueiredo","year":"2019","journal-title":"Histol. Histopathol."},{"issue":"6","key":"10.1016\/j.intimp.2025.115270_bb0300","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1002\/jcp.23015","article-title":"Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: differential effects of the mechanotransducer CD31","volume":"227","author":"Glen","year":"2012","journal-title":"J. Cell. Physiol."},{"issue":"20","key":"10.1016\/j.intimp.2025.115270_bb0305","article-title":"Mesenchymal stem cell aggregation-released extracellular vesicles induce CD31(+) EMCN(+) vessels in skin regeneration and improve diabetic wound healing","volume":"12","author":"Liu","year":"2023","journal-title":"Adv. Healthc. Mater."},{"issue":"3 Pt B","key":"10.1016\/j.intimp.2025.115270_bb0310","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.scr.2014.04.009","article-title":"New vessel formation in the context of cardiomyocyte regeneration--the role and importance of an adequate perfusing vasculature","volume":"13","author":"Michelis","year":"2014","journal-title":"Stem Cell Res."},{"issue":"4","key":"10.1016\/j.intimp.2025.115270_bb0315","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/jcu.22902","article-title":"Endothelial dysfunction in patients with myocardial ischemia or infarction and nonobstructive coronary arteries","volume":"49","author":"Simsek","year":"2021","journal-title":"J. Clin. Ultrasound"},{"key":"10.1016\/j.intimp.2025.115270_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101107","article-title":"NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis","volume":"23","author":"Dodson","year":"2019","journal-title":"Redox Biol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925012603?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925012603?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T05:15:51Z","timestamp":1757913351000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925012603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":64,"alternative-id":["S1567576925012603"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.115270","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Muscone attenuates myocardial infarction by regulating ferroptosis of cardiomyocytes through Nrf2\/system Xc-\/GPX4 signaling pathway","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.115270","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115270"}}