{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T02:59:48Z","timestamp":1771729188999,"version":"3.50.1"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171410"],"award-info":[{"award-number":["82171410"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2023MH340"],"award-info":[{"award-number":["ZR2023MH340"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021MH098"],"award-info":[{"award-number":["ZR2021MH098"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024MH322"],"award-info":[{"award-number":["ZR2024MH322"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","award":["2022YP93"],"award-info":[{"award-number":["2022YP93"]}],"id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","award":["202134018"],"award-info":[{"award-number":["202134018"]}],"id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009108","name":"Shandong University","doi-asserted-by":"publisher","award":["6010219009"],"award-info":[{"award-number":["6010219009"]}],"id":[{"id":"10.13039\/100009108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015642","name":"Project of Shandong Province Higher Educational Science and Technology Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015642","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.intimp.2025.116039","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T01:20:16Z","timestamp":1766020816000},"page":"116039","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["IL-24 ameliorates cognitive dysfunction via the inhibition PERK-eIF2\u03b1 Signaling pathway in Alzheimer's disease"],"prefix":"10.1016","volume":"169","author":[{"given":"Yansheng","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyi","family":"Yue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengrun","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiuzhou","family":"Diao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoyang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianzhong","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingbo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2025.116039_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101304","article-title":"Exploring the multifunctional role of melatonin in regulating autophagy and sleep to mitigate Alzheimer\u2019s disease neuropathology","volume":"67","author":"Hossain","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.intimp.2025.116039_bb0010","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1186\/s12974-020-01968-1","article-title":"The immune system on the TRAIL of Alzheimer\u2019s disease","volume":"17","author":"Burgaletto","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2025.116039_bb0015","first-page":"2727","article-title":"Single-cell RNA sequencing of peripheral blood reveals immune cell signatures in Alzheimer\u2019s disease","volume":"12","author":"Xu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.116039_bb0020","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s13195-017-0297-z","article-title":"Alzheimer\u2019s disease prevention: from risk factors to early intervention","volume":"9","author":"Crous-Bou","year":"2017","journal-title":"Alzheimer\u2019s Res. Ther."},{"key":"10.1016\/j.intimp.2025.116039_bb0025","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.3233\/JAD-170769","article-title":"A \u2018Framingham-like\u2019 algorithm for predicting 4-year risk of progression to amnestic mild cognitive impairment or Alzheimer\u2019s disease using multidomain information","volume":"63","author":"Steenland","year":"2018","journal-title":"J. Alzheimer\u2019s Dis"},{"key":"10.1016\/j.intimp.2025.116039_bb0030","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/alz.12328","article-title":"2021 Alzheimer's disease facts and figures","volume":"17","year":"2021","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.intimp.2025.116039_bb0035","doi-asserted-by":"crossref","first-page":"S167","DOI":"10.37765\/ajmc.2020.88481","article-title":"Current and evolving treatment strategies for the Alzheimer disease continuum","volume":"26","author":"Marasco","year":"2020","journal-title":"Am. J. Manag. Care"},{"key":"10.1016\/j.intimp.2025.116039_bb0040","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.14506.1","article-title":"Current understanding of Alzheimer's disease diagnosis and treatment","volume":"7","author":"Weller","year":"2018","journal-title":"F1000Res"},{"key":"10.1016\/j.intimp.2025.116039_bb0045","doi-asserted-by":"crossref","first-page":"559","DOI":"10.2174\/1567205016666190321154618","article-title":"Systemic and CNS inflammation crosstalk: implications for Alzheimer\u2019s disease","volume":"16","author":"Paouri","year":"2019","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.intimp.2025.116039_bb0050","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3233\/JAD-2009-1015","article-title":"Dramatic shifts in circulating CD4 but not CD8 T cell subsets in mild Alzheimer\u2019s disease","volume":"17","author":"Larbi","year":"2009","journal-title":"J. Alzheimer\u2019s Dis"},{"key":"10.1016\/j.intimp.2025.116039_bb0055","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/s41586-019-1895-7","article-title":"Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease","volume":"577","author":"Gate","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2025.116039_bb0060","doi-asserted-by":"crossref","first-page":"783","DOI":"10.3389\/fimmu.2017.00783","article-title":"Differential phenotypes of myeloid-derived suppressor and T regulatory cells and cytokine levels in amnestic mild cognitive impairment subjects compared to mild Alzheimer diseased patients","volume":"8","author":"Le Page","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2025.116039_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21176127","article-title":"Endoplasmic reticulum stress and unfolded protein response in neurodegenerative diseases","volume":"21","author":"Ghemrawi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2025.116039_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2021.101417","article-title":"Exploring ER stress response in cellular aging and neuroinflammation in Alzheimer\u2019s disease","author":"Uddin","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.intimp.2025.116039_bb0075","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s13024-017-0183-y","article-title":"Endoplasmic reticulum stress and inflammation in the central nervous system","volume":"12","author":"Sprenkle","year":"2017","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.intimp.2025.116039_bb0080","doi-asserted-by":"crossref","first-page":"12625","DOI":"10.1073\/pnas.220247197","article-title":"PERK mediates cell-cycle exit during the mammalian unfolded protein response","volume":"97","author":"Brewer","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.intimp.2025.116039_bb0085","first-page":"885","article-title":"Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2\u03b1 pathway","volume":"2012","author":"Mouton-Liger","year":"1822","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.intimp.2025.116039_bb0090","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.neurobiolaging.2013.01.008","article-title":"Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation","volume":"34","author":"Nijholt","year":"2013","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.intimp.2025.116039_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.104702","article-title":"Endoplasmic reticulum stress signaling in cancer and neurodegenerative disorders: tools and strategies to understand its complexity","volume":"155","author":"da Silva","year":"2020","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.intimp.2025.116039_bb0100","article-title":"Pathogenesis and promising therapeutics of Alzheimer disease through eIF2\u03b1 pathway and correspondent kinases","volume":"35","author":"Majd","year":"2020","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.intimp.2025.116039_bb0105","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/bs.acr.2018.02.005","article-title":"Role of MDA-7\/IL-24 a multifunction protein in human diseases","volume":"138","author":"Menezes","year":"2018","journal-title":"Adv. Cancer Res."},{"key":"10.1016\/j.intimp.2025.116039_bb0110","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12967-021-02890-7","article-title":"Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases","volume":"19","author":"\u00d3nody","year":"2021","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2025.116039_bb0115","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12974-019-1444-1","article-title":"Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine","volume":"16","author":"Burmeister","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2025.116039_bb0120","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23010072","article-title":"Insights into the mechanisms of action of MDA-7\/IL-24: a ubiquitous Cancer-suppressing protein","volume":"23","author":"Modi","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2025.116039_bb0125","doi-asserted-by":"crossref","DOI":"10.1001\/archneur.56.3.303","article-title":"Mild cognitive impairment\u202f: clinical characterization and outcome","volume":"56","author":"Petersen","year":"1999","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.intimp.2025.116039_bb0130","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jalz.2011.03.008","article-title":"The diagnosis of mild cognitive impairment due to Alzheimer\u2019s disease: recommendations from the National Institute on Aging-Alzheimer\u2019s Association workgroups on diagnostic guidelines for Alzheimer\u2019s disease","volume":"7","author":"Albert","year":"2011","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.intimp.2025.116039_bb0135","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/s41420-022-01187-y","article-title":"A new K(+)channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer's disease","volume":"8","author":"Piccirillo","year":"2022","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.intimp.2025.116039_bb0140","doi-asserted-by":"crossref","first-page":"861","DOI":"10.31083\/j.jin2004088","article-title":"Neurofilament light as a biomarker of axonal degeneration in patients with mild cognitive impairment and Alzheimer\u2019s disease","volume":"20","author":"Chen","year":"2021","journal-title":"J. Integr. Neurosci."},{"key":"10.1016\/j.intimp.2025.116039_bb0145","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1093\/brain\/awaa342","article-title":"Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer\u2019s disease","volume":"143","author":"Benedet","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.intimp.2025.116039_bb0150","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.neurobiolaging.2021.07.013","article-title":"CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer\u2019s disease dementia","volume":"107","author":"Lim","year":"2021","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.intimp.2025.116039_bb0155","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.biopsych.2020.02.001","article-title":"The \u03b2-secretase BACE1 in Alzheimer\u2019s disease","volume":"89","author":"Hampel","year":"2021","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.intimp.2025.116039_bb0160","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1007\/s11064-021-03504-w","article-title":"Curcumin attenuates the PERK-eIF2\u03b1 Signaling to relieve acrylamide-induced neurotoxicity in SH-SY5Y neuroblastoma cells","volume":"47","author":"Yan","year":"2022","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.intimp.2025.116039_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103970","article-title":"Human tau accumulation promotes glycogen synthase kinase-3\u03b2 acetylation and thus upregulates the kinase: a vicious cycle in Alzheimer neurodegeneration","volume":"78","author":"Zhou","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.intimp.2025.116039_bb0170","doi-asserted-by":"crossref","first-page":"45937","DOI":"10.1074\/jbc.M306268200","article-title":"Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418","volume":"278","author":"Bhat","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2025.116039_bb0175","doi-asserted-by":"crossref","DOI":"10.3390\/cells9030531","article-title":"Memory CD4(+) T cells in immunity and autoimmune diseases","volume":"9","author":"Raphael","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.intimp.2025.116039_bb0180","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.1038\/s41467-018-05489-7","article-title":"T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells","volume":"9","author":"Jain","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2025.116039_bb0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008074","article-title":"Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals","volume":"15","author":"Wonderlich","year":"2019","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.intimp.2025.116039_bb0190","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.nrl.2018.10.004","article-title":"Peripheral blood lymphocyte phenotypes in Alzheimer and Parkinson\u2019s diseases","volume":"37","author":"Garfias","year":"2022","journal-title":"Neurologia (Engl Ed)"},{"key":"10.1016\/j.intimp.2025.116039_bb0195","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1136\/jnnp-2020-323603","article-title":"Peripheral immunophenotype in dementia with Lewy bodies and Alzheimer\u2019s disease: an observational clinical study","volume":"91","author":"Amin","year":"2020","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.intimp.2025.116039_bb0200","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1038\/s41467-021-22479-4","article-title":"Therapeutic B-cell depletion reverses progression of Alzheimer\u2019s disease","volume":"12","author":"Kim","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2025.116039_bb0205","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23020627","article-title":"Interleukin-24 immunobiology and its roles in inflammatory diseases","volume":"23","author":"Zhong","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2025.116039_bb0210","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.immuni.2020.06.022","article-title":"The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24","volume":"53","author":"Chong","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.intimp.2025.116039_bb0215","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20212443","article-title":"IL-24 intrinsically regulates Th17 cell pathogenicity in mice","volume":"219","author":"Sie","year":"2022","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2025.116039_bb0220","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/nn.3486","article-title":"Suppression of eIF2\u03b1 kinases alleviates Alzheimer\u2019s disease-related plasticity and memory deficits","volume":"16","author":"Ma","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.intimp.2025.116039_bb0225","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.semcancer.2019.07.013","article-title":"Recent insights into apoptosis and toxic autophagy: the roles of MDA-7\/IL-24, a multidimensional anti-cancer therapeutic","volume":"66","author":"Emdad","year":"2020","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.intimp.2025.116039_bb0230","doi-asserted-by":"crossref","first-page":"47517","DOI":"10.1074\/jbc.M205114200","article-title":"Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions","volume":"277","author":"Parrish-Novak","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2025.116039_bb0235","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1089\/ars.2007.1797","article-title":"Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner","volume":"9","author":"Chafekar","year":"2007","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.intimp.2025.116039_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2022.120356","article-title":"Protective and anti-oxidative effects of curcumin and resveratrol on a\u03b2-oligomer-induced damage in the SH-SY5Y cell line","volume":"441","author":"Yu","year":"2022","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.intimp.2025.116039_bb0245","article-title":"T\u03b24 ameliorates oxidative damage and apoptosis through ERK\/MAPK and 5-HT1A signaling pathway in a\u03b2 insulted SH-SY5Y cells","volume":"120178","author":"Zhang","year":"2021","journal-title":"Life Sci."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925020284?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576925020284?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T02:09:51Z","timestamp":1771726191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576925020284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":49,"alternative-id":["S1567576925020284"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2025.116039","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IL-24 ameliorates cognitive dysfunction via the inhibition PERK-eIF2\u03b1 Signaling pathway in Alzheimer's disease","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2025.116039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116039"}}