{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:25:05Z","timestamp":1786991105377,"version":"build-2736575974"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2022xkjT010"],"award-info":[{"award-number":["2022xkjT010"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2023xkjT049"],"award-info":[{"award-number":["2023xkjT049"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017128","name":"Science Fund for Distinguished Young Scholars of Anhui Province","doi-asserted-by":"publisher","award":["2408085J045"],"award-info":[{"award-number":["2408085J045"]}],"id":[{"id":"10.13039\/100017128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370630"],"award-info":[{"award-number":["82370630"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.intimp.2026.116231","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T04:18:21Z","timestamp":1769055501000},"page":"116231","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Rutin ameliorates hepatic ischemia-reperfusion injury by targeting CD36 to suppress hepatocyte ferroptosis"],"prefix":"10.1016","volume":"172","author":[{"given":"Zhenlong","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaomiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenmei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenna","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengjiang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hehang","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changlin","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taotao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.intimp.2026.116231_bb0005","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1097\/HEP.0000000000000773","article-title":"Endothelial YAP\/TEAD1-CXCL17 signaling recruits myeloid-derived suppressor cells against liver ischemia-reperfusion injury","volume":"81","author":"Zhang","year":"2025","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0010","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/HEP.0000000000000716","article-title":"m6A-mediated gluconeogenic enzyme PCK1 upregulation protects against hepatic ischemia-reperfusion injury","volume":"81","author":"Yu","year":"2025","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/cvr\/cvaa319","article-title":"The role of CD36 in cardiovascular disease","volume":"118","author":"Shu","year":"2020","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.intimp.2026.116231_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103258","article-title":"Cellular and molecular mechanisms of hepatic ischemia-reperfusion injury: the role of oxidative stress and therapeutic approaches","volume":"75","author":"George","year":"2024","journal-title":"Redox Biol."},{"issue":"11","key":"10.1016\/j.intimp.2026.116231_bb0025","doi-asserted-by":"crossref","first-page":"3856","DOI":"10.7150\/thno.82607","article-title":"Hepatocyte HSPA12A inhibits macrophage chemotaxis and activation to attenuate liver ischemia\/reperfusion injury via suppressing glycolysis-mediated HMGB1 lactylation and secretion of hepatocytes","volume":"13","author":"Du","year":"2023","journal-title":"Theranostics"},{"issue":"12","key":"10.1016\/j.intimp.2026.116231_bb0030","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/s41419-023-06294-x","article-title":"Gp78 deficiency in hepatocytes alleviates hepatic ischemia-reperfusion injury via suppressing ACSL4-mediated ferroptosis","volume":"14","author":"Li","year":"2023","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0035","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jhep.2021.11.026","article-title":"Myeloid Ikaros\u2013SIRT1 signaling axis regulates hepatic inflammation and pyroptosis in ischemia-stressed mouse and human liver","volume":"76","author":"Kadono","year":"2022","journal-title":"J. Hepatol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0040","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/S0016-5085(03)01209-5","article-title":"Apoptosis versus oncotic necrosis in hepatic ischemia\/reperfusion injury","volume":"125","author":"Jaeschke","year":"2003","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.intimp.2026.116231_bb0045","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.jhep.2025.02.029","article-title":"Circadian control of hepatic ischemia\/reperfusion injury via HSD17B13-mediated autophagy in hepatocytes","volume":"83","author":"Wang","year":"2025","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0050","doi-asserted-by":"crossref","first-page":"4760","DOI":"10.1038\/s41467-024-49202-3","article-title":"FTO deficiency in older livers exacerbates ferroptosis during ischaemia\/reperfusion injury by upregulating ACSL4 and TFRC","volume":"15","author":"Li","year":"2024","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0055","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116231_bb0060","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1021\/acs.jmedchem.5b01641","article-title":"Novel Ferroptosis inhibitors with improved potency and ADME properties","volume":"59","author":"Hofmans","year":"2016","journal-title":"J. Med. Chem."},{"issue":"12","key":"10.1016\/j.intimp.2026.116231_bb0065","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1038\/s41419-022-05518-w","article-title":"Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia\/reperfusion injury via suppressing GPX4-mediated ferroptosis","volume":"13","author":"Guo","year":"2022","journal-title":"Cell Death Dis."},{"issue":"5","key":"10.1016\/j.intimp.2026.116231_bb0070","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"R. Skouta, Eleina M. Zaitsev, Caroline E. Gleason, Darpan N. Patel, Andras J. Bauer, Alexandra M. Cantley, Wan S. Yang, B. Morrison, Brent R. Stockwell, Ferroptosis: An Iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"9","key":"10.1016\/j.intimp.2026.116231_bb0075","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1080\/15548627.2020.1810918","article-title":"Ferroptosis: machinery and regulation","volume":"17","author":"Chen","year":"2021","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0080","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41556-021-00818-3","article-title":"PKC\u03b2II phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis","volume":"24","author":"Zhang","year":"2022","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0085","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1038\/s41467-020-18565-8","article-title":"CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis","volume":"11","author":"Hao","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116231_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2024.155914","article-title":"O-GlcNAcylation promotes the progression of nonalcoholic fatty liver disease by upregulating the expression and function of CD36","volume":"156","author":"Zhu","year":"2024","journal-title":"Metabolism"},{"issue":"3","key":"10.1016\/j.intimp.2026.116231_bb0095","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1681\/ASN.2008010009","article-title":"CD36 regulates oxidative stress and inflammation in Hypercholesterolemic CKD","volume":"20","author":"Okamura","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116231_bb0100","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.cmet.2021.02.015","article-title":"CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability","volume":"33","author":"Ma","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.intimp.2026.116231_bb0105","doi-asserted-by":"crossref","DOI":"10.1093\/burnst\/tkad055","article-title":"Propofol and salvianolic acid a synergistically attenuated cardiac ischemia\u2013reperfusion injury in diabetic mice via modulating the CD36\/AMPK pathway","volume":"12","author":"Zhou","year":"2024","journal-title":"Burns Trauma"},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0110","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/micr.20345","article-title":"Rutin in rat liver ischemia\/reperfusion injury: effect on DDAH\/NOS pathway","volume":"27","author":"Lanteri","year":"2007","journal-title":"Microsurgery"},{"issue":"3","key":"10.1016\/j.intimp.2026.116231_bb0115","first-page":"G664","article-title":"Beneficial effects of rutin and l-arginine coadministration in a rat model of liver ischemia-reperfusion injury, American journal of physiology-gastrointestinal and liver","volume":"296","author":"Acquaviva","year":"2009","journal-title":"Physiology"},{"issue":"11","key":"10.1016\/j.intimp.2026.116231_bb0120","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1016\/j.cmet.2024.09.007","article-title":"Sensing steroid hormone 17\u03b1-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury","volume":"36","author":"Lin","year":"2024","journal-title":"Cell Metab."},{"key":"10.1016\/j.intimp.2026.116231_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.119894","article-title":"Homocapsaicin II induce ferroptosis in colorectal cancer cells via cholesterol-centrosome amplification-multipolarity axis","volume":"348","author":"Wang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.116231_bb0130","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.phrs.2018.12.014","article-title":"Protective effects of curcumin against ischemia-reperfusion injury in the liver","volume":"141","author":"Bavarsad","year":"2019","journal-title":"Pharmacol. Res."},{"issue":"6","key":"10.1016\/j.intimp.2026.116231_bb0135","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jcmgh.2023.03.003","article-title":"Mechanistic insight and clinical implications of ischemia\/reperfusion injury post liver transplantation","volume":"15","author":"Liu","year":"2023","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0140","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3350\/cmh.2024.0222","article-title":"Current status and perspective on molecular targets and therapeutic intervention strategy in hepatic ischemia-reperfusion injury","volume":"30","author":"Liu","year":"2024","journal-title":"Clin. Mol. Hepatol."},{"key":"10.1016\/j.intimp.2026.116231_bb0145","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.redox.2018.10.019","article-title":"Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress","volume":"20","author":"Bi","year":"2019","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0150","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jhep.2025.01.012","article-title":"GRINA alleviates hepatic ischemia\u2013reperfusion injury-induced apoptosis and ER-phagy by enhancing HRD1-mediated ATF6 ubiquitination","volume":"83","author":"Yu","year":"2025","journal-title":"J. Hepatol."},{"key":"10.1016\/j.intimp.2026.116231_bb0155","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.jare.2024.05.010","article-title":"Quercetin, a natural flavonoid, protects against hepatic ischemia\u2013reperfusion injury via inhibiting Caspase-8\/ASC dependent macrophage pyroptosis","volume":"70","author":"Lin","year":"2025","journal-title":"J. Adv. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0160","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1016\/j.apsb.2025.03.002","article-title":"Acteoside ameliorates hepatocyte ferroptosis and hepatic ischemia-reperfusion injury via targeting PCBP2","volume":"15","author":"Jia","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0165","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1681\/ASN.0000000000000027","article-title":"Hypoxia-inducible factor 2\u03b1 attenuates renal ischemia-reperfusion injury by suppressing CD36-mediated lipid accumulation in dendritic cells in a mouse model","volume":"34","author":"Qu","year":"2023","journal-title":"J. Am. Soc. Nephrol."},{"issue":"3","key":"10.1016\/j.intimp.2026.116231_bb0170","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.jhep.2018.04.006","article-title":"CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis","volume":"69","author":"Zhao","year":"2018","journal-title":"J. Hepatol."},{"key":"10.1016\/j.intimp.2026.116231_bb0175","article-title":"CD36 promotes Iron accumulation and dysfunction in CD8+ T cells via the p38-CEBPB-TfR1 Axis in early-stage hepatocellular carcinoma","volume":"0","author":"Qin","year":"2025","journal-title":"Korean J. Hepatol."},{"key":"10.1016\/j.intimp.2026.116231_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107567","article-title":"LIX1L aggravates MASH-HCC progression by reprogramming of hepatic metabolism and microenvironment via CD36","volume":"211","author":"Leng","year":"2025","journal-title":"Pharmacol. Res."},{"issue":"14","key":"10.1016\/j.intimp.2026.116231_bb0185","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1161\/CIRCULATIONAHA.117.027505","article-title":"Linking metabolic dysfunction to atherosclerosis via activation of macrophage CD36 gene transcription by retinol binding Protein-4","volume":"135","author":"Silverstein","year":"2017","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.intimp.2026.116231_bb0190","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1080\/15548627.2023.2196876","article-title":"Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury","volume":"19","author":"Li","year":"2023","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0195","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1038\/s41467-020-18565-8","article-title":"CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis","volume":"11","author":"Hao","year":"2020","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.intimp.2026.116231_bb0200","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1161\/CIRCRESAHA.119.315833","article-title":"Mitochondrial metabolic reprogramming by CD36 signaling drives macrophage inflammatory responses","volume":"125","author":"Chen","year":"2019","journal-title":"Circ. Res."},{"issue":"11","key":"10.1016\/j.intimp.2026.116231_bb0205","article-title":"The lactate-primed KAT8\u2013PCK2 Axis exacerbates hepatic Ferroptosis during ischemia\/reperfusion injury by reprogramming OXSM-dependent mitochondrial fatty acid synthesis","volume":"12","author":"Yuan","year":"2025","journal-title":"Adv Sci (Weinh)"},{"issue":"2","key":"10.1016\/j.intimp.2026.116231_bb0210","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.kint.2021.10.028","article-title":"Dephosphorylation of AMP-activated protein kinase exacerbates ischemia\/reperfusion-induced acute kidney injury via mitochondrial dysfunction","volume":"101","author":"Ma","year":"2022","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0215","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.intimp.2026.116231_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2024.156127","article-title":"CD36-mediated uptake of oxidized LDL induces double-negative regulatory T cell ferroptosis in metabolic dysfunction-associated steatotic liver disease","volume":"164","author":"Wei","year":"2025","journal-title":"Metabolism"},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0225","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jhep.2024.09.029","article-title":"FABP5+ lipid-loaded macrophages process tumour-derived unsaturated fatty acid signal to suppress T-cell antitumour immunity","volume":"82","author":"Yang","year":"2025","journal-title":"J. Hepatol."},{"issue":"21","key":"10.1016\/j.intimp.2026.116231_bb0230","article-title":"Asprosin-FABP5 interaction modulates mitochondrial fatty acid oxidation through PPAR\u03b1 contributing to MASLD development","volume":"12","author":"Yu","year":"2025","journal-title":"Adv Sci (Weinh)"},{"issue":"15","key":"10.1016\/j.intimp.2026.116231_bb0235","doi-asserted-by":"crossref","first-page":"6561","DOI":"10.7150\/thno.44868","article-title":"FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism","volume":"10","author":"Zhang","year":"2020","journal-title":"Theranostics"},{"issue":"4","key":"10.1016\/j.intimp.2026.116231_bb0240","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/s41419-024-06681-y","article-title":"Fatty acid-binding protein 5 is a functional biomarker and indicator of ferroptosis in cerebral hypoxia","volume":"15","author":"Peng","year":"2024","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.intimp.2026.116231_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102547","article-title":"Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons","volume":"59","author":"Guo","year":"2023","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116231_bb0250","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.immuni.2024.03.019","article-title":"Ironing out the role of ferroptosis in immunity","volume":"57","author":"Bell","year":"2024","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.intimp.2026.116231_bb0255","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s43556-024-00227-6","article-title":"Pentraxin-3 modulates hepatocyte ferroptosis and the innate immune response in LPS-induced liver injury","volume":"5","author":"Wang","year":"2024","journal-title":"Mol Biomed"},{"issue":"9","key":"10.1016\/j.intimp.2026.116231_bb0260","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1038\/s41401-024-01299-4","article-title":"Bevacizumab induces ferroptosis and enhances CD8(+) T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9","volume":"45","author":"Hou","year":"2024","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.intimp.2026.116231_bb0265","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jare.2023.02.007","article-title":"Bavachinin protects the liver in NAFLD by promoting regeneration via targeting PCNA","volume":"55","author":"Dong","year":"2024","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.intimp.2026.116231_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116427","article-title":"Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication","volume":"311","author":"Zhao","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"16","key":"10.1016\/j.intimp.2026.116231_bb0275","doi-asserted-by":"crossref","first-page":"8593","DOI":"10.1039\/D2FO00282E","article-title":"Hepatoprotective effects of different mulberry leaf extracts against acute liver injury in rats by alleviating oxidative stress and inflammatory response","volume":"13","author":"Yu","year":"2022","journal-title":"Food Funct."},{"issue":"21","key":"10.1016\/j.intimp.2026.116231_bb0280","doi-asserted-by":"crossref","first-page":"2002273","DOI":"10.1002\/advs.202002273","article-title":"The nuclear orphan receptor NR2F6 promotes hepatic steatosis through upregulation of fatty acid transporter CD36","volume":"7","author":"Zhou","year":"2020","journal-title":"Adv Sci (Weinh)"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926000743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926000743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T12:29:17Z","timestamp":1775305757000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926000743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":56,"alternative-id":["S1567576926000743"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116231","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rutin ameliorates hepatic ischemia-reperfusion injury by targeting CD36 to suppress hepatocyte ferroptosis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116231","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116231"}}