{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:57:53Z","timestamp":1790841473767,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012154","name":"Graduate Research and Innovation Projects of Jiangsu Province","doi-asserted-by":"publisher","award":["KYCX25_3799"],"award-info":[{"award-number":["KYCX25_3799"]}],"id":[{"id":"10.13039\/501100012154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016806","name":"Natural Science Foundation of Nantong Municipality","doi-asserted-by":"publisher","award":["JC2023092"],"award-info":[{"award-number":["JC2023092"]}],"id":[{"id":"10.13039\/100016806","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102720"],"award-info":[{"award-number":["82102720"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82473448"],"award-info":[{"award-number":["82473448"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Jiangsu Province Natural Science Foundation","doi-asserted-by":"publisher","award":["BK20221272"],"award-info":[{"award-number":["BK20221272"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.intimp.2026.116475","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T12:57:44Z","timestamp":1773493064000},"page":"116475","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["RASSF1A inhibits gastric cancer metastasis by reducing neutrophil infiltration and neutrophil extracellular trap formation via ribosome biogenesis"],"prefix":"10.1016","volume":"176","author":[{"given":"Yu","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingchen","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shukang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanjiang","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfeng","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.intimp.2026.116475_bb0005","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.intimp.2026.116475_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2023.101834","article-title":"Development of a tongue image-based machine learning tool for the diagnosis of gastric cancer: a prospective multicentre clinical cohort study","volume":"57","author":"Yuan","year":"2023","journal-title":"EClinicalMedicine"},{"issue":"12","key":"10.1016\/j.intimp.2026.116475_bb0015","article-title":"Enhanced photodynamic therapy synergizing with inhibition of tumor neutrophil ferroptosis boosts anti-PD-1 therapy of gastric cancer","volume":"11","author":"Zhu","year":"2024","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.intimp.2026.116475_bb0020","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1267186","article-title":"Comprehensive multi-omics analysis of tryptophan metabolism-related gene expression signature to predict prognosis in gastric cancer","volume":"14","author":"Luo","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116475_bb0025","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1152\/physrev.00012.2018","article-title":"The neutrophil\u2019s role during health and disease","volume":"99","author":"Liew","year":"2019","journal-title":"Physiol. Rev."},{"issue":"2","key":"10.1016\/j.intimp.2026.116475_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2024.114191","article-title":"NETs: important players in cancer progression and therapeutic resistance","volume":"441","author":"Guan","year":"2024","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.intimp.2026.116475_bb0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.semcancer.2021.07.011","article-title":"Neutrophil extracellular traps in cancer","volume":"79","author":"Cristinziano","year":"2022","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.intimp.2026.116475_bb0040","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.01749","article-title":"The emerging role of neutrophil extracellular traps (NETs) in tumor progression and metastasis","volume":"11","author":"Masucci","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116475_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2021.101538","article-title":"Versatile neutrophil functions in cancer","volume":"57","author":"Siwicki","year":"2021","journal-title":"Semin. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116475_bb0050","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/path.5860","article-title":"Neutrophil extracellular traps drive epithelial-mesenchymal transition of human colon cancer","volume":"256","author":"Stehr","year":"2022","journal-title":"J. Pathol."},{"issue":"7814","key":"10.1016\/j.intimp.2026.116475_bb0055","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41586-020-2394-6","article-title":"DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25","volume":"583","author":"Yang","year":"2020","journal-title":"Nature"},{"issue":"17","key":"10.1016\/j.intimp.2026.116475_bb0060","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.146133","article-title":"DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis","volume":"6","author":"Deng","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.intimp.2026.116475_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2023.111014","article-title":"Neutrophil extracellular traps promote gastric cancer cell metastasis via the NAT10-mediated N4-acetylcytidine modification of SMYD2","volume":"116","author":"Liu","year":"2024","journal-title":"Cell. Signal."},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0070","doi-asserted-by":"crossref","DOI":"10.3892\/ijmm.2021.4960","article-title":"Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial-mesenchymal transition[J]","volume":"48","author":"Zhu","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.intimp.2026.116475_bb0075","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.cca.2020.01.014","article-title":"RASSF1A: a promising target for the diagnosis and treatment of cancer","volume":"504","author":"Bin","year":"2020","journal-title":"Clin. Chim. Acta"},{"issue":"2","key":"10.1016\/j.intimp.2026.116475_bb0080","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12548","article-title":"Circ_0078767 suppresses non-small-cell lung cancer by protecting RASSF1A expression via sponging miR-330-3p","volume":"52","author":"Chen","year":"2019","journal-title":"Cell Prolif."},{"key":"10.1016\/j.intimp.2026.116475_bb0085","doi-asserted-by":"crossref","DOI":"10.1186\/s13000-015-0317-x","article-title":"Combination of serum RASSF1A methylation and AFP is a promising non-invasive biomarker for HCC patient with chronic HBV infection","volume":"10","author":"Dong","year":"2015","journal-title":"Diagn. Pathol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116475_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036780","article-title":"The prognostic role of RASSF1A promoter methylation in breast cancer: a meta-analysis of published data","volume":"7","author":"Jiang","year":"2012","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.intimp.2026.116475_bb0095","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1038\/gt.2015.49","article-title":"Lentivirus-mediated RASSF1A expression suppresses aggressive phenotypes of gastric cancer cells in vitro and in vivo","volume":"22","author":"Zhou","year":"2015","journal-title":"Gene Ther."},{"issue":"3","key":"10.1016\/j.intimp.2026.116475_bb0100","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/cbin.11958","article-title":"RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK","volume":"47","author":"Bin","year":"2023","journal-title":"Cell Biol. Int."},{"issue":"35","key":"10.1016\/j.intimp.2026.116475_bb0105","doi-asserted-by":"crossref","first-page":"13131","DOI":"10.1074\/jbc.RA119.008970","article-title":"The tumor suppressor RASSF1A modulates inflammation and injury in the reperfused murine myocardium","volume":"294","author":"Francisco","year":"2019","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.intimp.2026.116475_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0075483","article-title":"The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury","volume":"8","author":"Gordon","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0115","doi-asserted-by":"crossref","DOI":"10.1186\/s10020-024-00832-9","article-title":"ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis","volume":"30","author":"He","year":"2024","journal-title":"Mol. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0120","doi-asserted-by":"crossref","DOI":"10.1186\/s12935-024-03359-5","article-title":"Mir-605-3p prevents liver premetastatic niche formation by inhibiting angiogenesis via decreasing exosomal nos3 release in gastric cancer","volume":"24","author":"Hu","year":"2024","journal-title":"Cancer Cell Int."},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0125","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1186\/s13046-021-02110-6","article-title":"DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-kappaB signaling pathway by targeting TRAF1 in hepatocellular carcinoma","volume":"40","author":"Zhu","year":"2021","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0130","doi-asserted-by":"crossref","DOI":"10.1186\/s13046-020-01620-z","article-title":"BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer","volume":"39","author":"Liu","year":"2020","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.intimp.2026.116475_bb0135","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/neuonc\/noac286","article-title":"Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth","volume":"25","author":"Zisi","year":"2023","journal-title":"Neuro-Oncology"},{"issue":"9","key":"10.1016\/j.intimp.2026.116475_bb0140","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1158\/1078-0432.CCR-18-3684","article-title":"Loss of SMAD4 promotes colorectal cancer progression by recruiting tumor-associated neutrophils via the CXCL1\/8-CXCR2 axis","volume":"25","author":"Ogawa","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"5","key":"10.1016\/j.intimp.2026.116475_bb0145","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2023-008662","article-title":"CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs","volume":"12","author":"Xiong","year":"2024","journal-title":"J. Immunother. Cancer"},{"issue":"2","key":"10.1016\/j.intimp.2026.116475_bb0150","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1084\/jem.20181102","article-title":"Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis","volume":"216","author":"Weckbach","year":"2019","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2026.116475_bb0155","article-title":"Decreased miR-4512 levels in monocytes and macrophages of individuals with systemic lupus erythematosus contribute to innate immune activation and neutrsophil NETosis by targeting TLR4 and CXCL2","volume":"12","author":"Yang","year":"2021","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2026.116475_bb0160","doi-asserted-by":"crossref","first-page":"3682","DOI":"10.1158\/0008-5472.CAN-04-2792","article-title":"RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression","volume":"65","author":"Whang","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.intimp.2026.116475_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116759","article-title":"Empagliflozin attenuates doxorubicin-induced cardiotoxicity by inhibiting the JNK signaling pathway","volume":"176","author":"Chang","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2026.116475_bb0170","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cbi.2017.08.011","article-title":"Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells","volume":"277","author":"Lu","year":"2017","journal-title":"Chem. Biol. Interact."},{"issue":"6","key":"10.1016\/j.intimp.2026.116475_bb0175","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1128\/MCB.25.6.2130-2137.2005","article-title":"TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling","volume":"25","author":"Kim","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.intimp.2026.116475_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216903","article-title":"Acetyl-CoA metabolic accumulation promotes hepatocellular carcinoma metastasis via enhancing CXCL1-dependent infiltration of tumor-associated neutrophils","volume":"592","author":"Pan","year":"2024","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0185","article-title":"Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps","volume":"14","author":"Wang","year":"2023","journal-title":"Nat. Commun."},{"issue":"41","key":"10.1016\/j.intimp.2026.116475_bb0190","article-title":"SKAP1 expression in Cancer cells enhances Colon tumor growth and impairs cytotoxic immunity by promoting neutrophil extracellular trap formation via the NFATc1\/CXCL8 Axis","volume":"11","author":"Gao","year":"2024","journal-title":"Adv Sci (Weinh)"},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0195","doi-asserted-by":"crossref","DOI":"10.3390\/biom14010031","article-title":"Loss of the DYRK1A protein kinase results in the reduction in ribosomal protein gene expression, ribosome mass and reduced translation","volume":"14","author":"Di Vona","year":"2023","journal-title":"Biomolecules"},{"issue":"9","key":"10.1016\/j.intimp.2026.116475_bb0200","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10092088","article-title":"Ribosome-directed therapies in cancer","volume":"10","author":"Temaj","year":"2022","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0205","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41392-022-01285-4","article-title":"Ribosome biogenesis in disease: new players and therapeutic targets","volume":"8","author":"Jiao","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.intimp.2026.116475_bb0210","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.semcdb.2014.08.004","article-title":"mTORC1 signaling controls multiple steps in ribosome biogenesis","volume":"36","author":"Iadevaia","year":"2014","journal-title":"Semin. Cell Dev. Biol."},{"issue":"11","key":"10.1016\/j.intimp.2026.116475_bb0215","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21114037","article-title":"Myc as a regulator of ribosome biogenesis and cell competition: a link to cancer","volume":"21","author":"Destefanis","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"30","key":"10.1016\/j.intimp.2026.116475_bb0220","doi-asserted-by":"crossref","first-page":"47875","DOI":"10.18632\/oncotarget.10293","article-title":"RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis","volume":"7","author":"Alkhatabi","year":"2016","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.intimp.2026.116475_bb0225","article-title":"Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation","volume":"9","author":"Li","year":"2018","journal-title":"Nat. Commun."},{"issue":"5209","key":"10.1016\/j.intimp.2026.116475_bb0230","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.7536344","article-title":"Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs","volume":"268","author":"Chen","year":"1995","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.intimp.2026.116475_bb0235","doi-asserted-by":"crossref","DOI":"10.3390\/cells9040857","article-title":"The JNK signaling pathway in inflammatory skin disorders and cancer","volume":"9","author":"Hammouda","year":"2020","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.intimp.2026.116475_bb0240","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1002\/med.21574","article-title":"JNK signaling in cancer cell survival","volume":"39","author":"Wu","year":"2019","journal-title":"Med. Res. Rev."},{"issue":"4","key":"10.1016\/j.intimp.2026.116475_bb0245","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.celrep.2018.06.101","article-title":"BLM potentiates c-Jun degradation and alters its function as an oncogenic transcription factor","volume":"24","author":"Priyadarshini","year":"2018","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.intimp.2026.116475_bb0250","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2174\/15680096113139990040","article-title":"Identification of the ZAK-MKK4-JNK-TGFbeta signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ","volume":"13","author":"Chen","year":"2013","journal-title":"Curr. Cancer Drug Targets"},{"issue":"10","key":"10.1016\/j.intimp.2026.116475_bb0255","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-024-07153-z","article-title":"Tumor-secreted LCN2 impairs gastric cancer progression via autocrine inhibition of the 24p3R\/JNK\/c-Jun\/SPARC axis","volume":"15","author":"Huang","year":"2024","journal-title":"Cell Death Dis."},{"issue":"9","key":"10.1016\/j.intimp.2026.116475_bb0260","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1158\/0008-5472.CAN-13-2136","article-title":"JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer","volume":"74","author":"Song","year":"2014","journal-title":"Cancer Res."},{"issue":"6","key":"10.1016\/j.intimp.2026.116475_bb0265","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.3892\/mmr.2013.1711","article-title":"JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner","volume":"8","author":"Lin","year":"2013","journal-title":"Mol. Med. Rep."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692600319X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692600319X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:14:40Z","timestamp":1790838880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156757692600319X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":53,"alternative-id":["S156757692600319X"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116475","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"RASSF1A inhibits gastric cancer metastasis by reducing neutrophil infiltration and neutrophil extracellular trap formation via ribosome biogenesis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116475","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116475"}}