{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:57:18Z","timestamp":1790841438541,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005063","name":"Anhui Province Excellent Young Talents Fund Program of Higher Education Institutions","doi-asserted-by":"publisher","award":["2023AH040078"],"award-info":[{"award-number":["2023AH040078"]}],"id":[{"id":"10.13039\/501100005063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370591"],"award-info":[{"award-number":["82370591"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003995","name":"Anhui Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["1908085J30"],"award-info":[{"award-number":["1908085J30"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2023lhpysfjd023"],"award-info":[{"award-number":["2023lhpysfjd023"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2022xkjT045"],"award-info":[{"award-number":["2022xkjT045"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["H2023031"],"award-info":[{"award-number":["H2023031"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["gxbjZD2021048"],"award-info":[{"award-number":["gxbjZD2021048"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.intimp.2026.116484","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T10:29:39Z","timestamp":1773397779000},"page":"116484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["ASIC1a promotes alveolar epithelial apoptosis and acute lung injury through repression of the LncRNA00178\/miR-466b-3p\/Gucy1b1 ceRNA network"],"prefix":"10.1016","volume":"176","author":[{"given":"Anqi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueqin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruohan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shishun","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojie","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira","family":"Abou-Elnour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxing","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.intimp.2026.116484_bb0005","doi-asserted-by":"crossref","first-page":"394","DOI":"10.5414\/CP204438","article-title":"Research on acute lung injury inflammatory network","volume":"61","author":"Li","year":"2023","journal-title":"Int. J. Clin. Pharmacol. Ther."},{"key":"10.1016\/j.intimp.2026.116484_bb0010","doi-asserted-by":"crossref","unstructured":"Marquis KM, Hammer MM, Steinbrecher K, et al. CT approach to lung injury . Radiographics, 2023,43(7): e220176.","DOI":"10.1148\/rg.220176"},{"issue":"Suppl. 3","key":"10.1016\/j.intimp.2026.116484_bb0015","first-page":"S353","article-title":"Acute lung injury - from pathophysiology to treatment","volume":"69","author":"Mokr\u00e1","year":"2020","journal-title":"Physiol. Res."},{"key":"10.1016\/j.intimp.2026.116484_bb0020","unstructured":"Cho MS, Modi P, Sharma S. Transfusion-Related Acute Lung InjuryIn: StatPearls, Treasure Island (FL): StatPearls Publishing, September 15, 2023."},{"issue":"12","key":"10.1016\/j.intimp.2026.116484_bb0025","first-page":"730","article-title":"Acute respiratory distress syndrome: diagnosis and management","volume":"101","author":"Saguil","year":"2020","journal-title":"Am. Fam. Physician"},{"issue":"1","key":"10.1016\/j.intimp.2026.116484_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4046\/trd.2023.0104","article-title":"Subphenotypes of acute respiratory distress syndrome: advancing towards precision medicine","volume":"87","author":"Levine","year":"2024","journal-title":"Tuberc Respir Dis (Seoul)"},{"issue":"8","key":"10.1016\/j.intimp.2026.116484_bb0035","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1177\/0271678X221089074","article-title":"pH and proton-sensitive receptors in brain ischemia","volume":"42","author":"Zha","year":"2022","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"2","key":"10.1016\/j.intimp.2026.116484_bb0040","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/tox.24013","article-title":"ASIC1a contributes to the epithelial-mesenchymal transformation of breast cancer by activating the Ca2+ \/\u03b2-catenin pathway","volume":"39","author":"Wang","year":"2024","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.intimp.2026.116484_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.732869","article-title":"Changes in H+, K+, and Ca2+ concentrations, as observed in seizures, induce action potential Signaling in cortical neurons by a mechanism that depends partially on acid-sensing ion channels","volume":"15","author":"Alijevic","year":"2021","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.intimp.2026.116484_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1194948","article-title":"The role of acid sensing ion channels in the cardiovascular function","volume":"14","author":"L\u00f3pez-Ram\u00edrez","year":"2023","journal-title":"Front. Physiol."},{"key":"10.1016\/j.intimp.2026.116484_bb0055","doi-asserted-by":"crossref","unstructured":"Ge H, Zhou T, Zhang C, et al. Targeting ASIC1a promotes neural progenitor cell migration and neurogenesis in ischemic stroke. Research (Wash D C), 2023,6: 0105.","DOI":"10.34133\/research.0105"},{"issue":"11","key":"10.1016\/j.intimp.2026.116484_bb0060","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.2174\/1570159X19666210402102232","article-title":"The role of ASIC1a in epilepsy: a potential therapeutic target","volume":"19","author":"Cheng","year":"2021","journal-title":"Curr. Neuropharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116484_bb0065","doi-asserted-by":"crossref","first-page":"247","DOI":"10.7150\/thno.37200","article-title":"ASIC1a induces synovial inflammation via the Ca2+\/NFATc3\/ RANTES pathway","volume":"10","author":"Zhang","year":"2020","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.intimp.2026.116484_bb0070","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1186\/s12967-022-03781-1","article-title":"Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis","volume":"20","author":"Zai","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2026.116484_bb0075","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.molimm.2022.11.007","article-title":"Acid-sensitive ion channel 1a regulates TNF-\u03b1 expression in LPS-induced acute lung injury via ERS-CHOP-C\/EBP\u03b1 signaling pathway","volume":"153","author":"Liu","year":"2023","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.intimp.2026.116484_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.175296","article-title":"ASIC1a induces mitochondrial apoptotic responses in acute lung injury","volume":"934","author":"Li","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2026.116484_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120987","article-title":"N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1\u03b1\/glycolysis\/ASIC1a pathway","volume":"309","author":"Du","year":"2022","journal-title":"Life Sci."},{"issue":"10","key":"10.1016\/j.intimp.2026.116484_bb0090","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1080\/07391102.2017.1363087","article-title":"Molecular dynamics simulations investigate the mechanism of Psalmotoxin 1 regulating gating process of an acid-sensing ion channel 1a at pH 5.5","volume":"36","author":"Yu","year":"2018","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.intimp.2026.116484_bb0095","doi-asserted-by":"crossref","unstructured":"Bridges MC, Daulagala AC, Kourtidis A. LNCcation: LncRNA localization and function. J. Cell Biol., 2021,220(2): e202009045.","DOI":"10.1083\/jcb.202009045"},{"issue":"12","key":"10.1016\/j.intimp.2026.116484_bb0100","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1016\/j.molcel.2022.05.027","article-title":"Integrated LncRNA function upon genomic and epigenomic regulation","volume":"82","author":"Herman","year":"2022","journal-title":"Mol. Cell"},{"issue":"6","key":"10.1016\/j.intimp.2026.116484_bb0105","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41580-021-00447-6","article-title":"Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics","volume":"23","author":"Nojima","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116484_bb0110","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1093\/bib\/bbv031","article-title":"Revealing protein-LncRNA interaction","volume":"17","author":"Ferr\u00e8","year":"2016","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.intimp.2026.116484_bb0115","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/978-1-0716-1697-0_21","article-title":"Characterizing miRNA-LncRNA interplay","volume":"2372","author":"Karagkouni","year":"2021","journal-title":"Methods Mol. Biol."},{"issue":"7483","key":"10.1016\/j.intimp.2026.116484_bb0120","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nature12986","article-title":"The multilayered complexity of ceRNA crosstalk and competition","volume":"505","author":"Tay","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2026.116484_bb0125","doi-asserted-by":"crossref","unstructured":"Hakami MA, Hazazi A, Khan FR, et al. PVT1 LncRNA in lung cancer: a key player in tumorigenesis and therapeutic opportunities. Pathol. Res. Pract., 2024,253: 155019.","DOI":"10.1016\/j.prp.2023.155019"},{"key":"10.1016\/j.intimp.2026.116484_bb0130","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/978-3-030-92034-0_5","article-title":"LncRNAs and cardiovascular disease","volume":"1363","author":"Hennessy","year":"2022","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.intimp.2026.116484_bb0135","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/978-981-10-5203-3_9","article-title":"Understanding the role of LncRNAs in nervous system development","volume":"1008","author":"Clark","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.intimp.2026.116484_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2023.154955","article-title":"GAS5: a pivotal LncRNA in diabetes mellitus pathogenesis and management","volume":"253","author":"Alharbi","year":"2024","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.intimp.2026.116484_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106549","article-title":"The role of non-coding RNAs (miRNA and LncRNA) in the clinical management of rheumatoid arthritis","volume":"186","author":"Yang","year":"2022","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.intimp.2026.116484_bb0150","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.792884","article-title":"LncRNA expression profiles in systemic lupus erythematosus and rheumatoid arthritis: emerging biomarkers and therapeutic targets","volume":"12","author":"Wu","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2026.116484_bb0155","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.tig.2022.02.006","article-title":"Emerging concepts of miRNA therapeutics: from cells to clinic","volume":"38","author":"Diener","year":"2022","journal-title":"Trends Genet."},{"key":"10.1016\/j.intimp.2026.116484_bb0160","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2164-11-249","article-title":"Small RNA expression and strain specificity in the rat","volume":"11","author":"Linsen","year":"2010","journal-title":"BMC Genomics"},{"issue":"9","key":"10.1016\/j.intimp.2026.116484_bb0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0203713","article-title":"MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory \u03b2-cell damage","volume":"13","author":"Lindel\u00f8v Vestergaard","year":"2018","journal-title":"PloS One"},{"issue":"7","key":"10.1016\/j.intimp.2026.116484_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0200307","article-title":"Inhibition of ferrochelatase impairs vascular eNOS\/NO and sGC\/cGMP signaling","volume":"13","author":"Zhang","year":"2018","journal-title":"PloS One"},{"issue":"4","key":"10.1016\/j.intimp.2026.116484_bb0175","doi-asserted-by":"crossref","first-page":"R1448","DOI":"10.1152\/ajpregu.00341.2006","article-title":"Soluble guanylyl cyclase expression is reduced in LPS-induced lung injury","volume":"292","author":"Glynos","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"6","key":"10.1016\/j.intimp.2026.116484_bb0180","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1165\/rcmb.2014-0092OC","article-title":"Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation","volume":"52","author":"Glynos","year":"2015","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.intimp.2026.116484_bb0185","doi-asserted-by":"crossref","unstructured":"He H, Yang W, Su N, et al. Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. J. Exp. Med., 2023,220(2): e20211422.","DOI":"10.1084\/jem.20211422"},{"key":"10.1016\/j.intimp.2026.116484_bb0190","doi-asserted-by":"crossref","unstructured":"hu Y, Hu X, Wang L, et al. Recent advances in acid-sensitive ion channels in central nervous system diseases. Curr. Pharm. Des. 2022;28(17):1406\u20131411.","DOI":"10.2174\/1381612828666220422084159"},{"issue":"11","key":"10.1016\/j.intimp.2026.116484_bb0195","doi-asserted-by":"crossref","first-page":"14371","DOI":"10.1096\/fj.202001337R","article-title":"ASIC1a regulates miR-350\/SPRY2 by N6 -methyladenosine to promote liver fibrosis","volume":"34","author":"Zhu","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2026.116484_bb0200","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.molimm.2025.04.002","article-title":"Acid-sensing ion channel 1a promotes LPS-induced acute lung injury through the circRNA 18-658\/miR-127-5p\/TRIM72 axis","volume":"182","author":"Li","year":"2025","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.intimp.2026.116484_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120987","article-title":"N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1\u03b1\/glycolysis\/ASIC1a pathway","volume":"309","author":"Du","year":"2022","journal-title":"Life Sci."},{"issue":"10358","key":"10.1016\/j.intimp.2026.116484_bb0210","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0140-6736(22)01485-4","article-title":"Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes","volume":"400","author":"Bos","year":"2022","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.intimp.2026.116484_bb0215","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10753-022-01726-w","article-title":"The role of macrophages and alveolar epithelial cells in the development of ARDS","volume":"46","author":"Tao","year":"2023","journal-title":"Inflammation"},{"issue":"5","key":"10.1016\/j.intimp.2026.116484_bb0220","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1080\/08820139.2021.1928693","article-title":"LncRNA CASC2 alleviates Sepsis-induced acute lung injury by regulating the miR-152-3p\/PDK4 Axis","volume":"51","author":"Zhu","year":"2022","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.intimp.2026.116484_bb0225","doi-asserted-by":"crossref","unstructured":"Chen J, Liu Q, Ding Z, et al. LncRNA NEAT1 aggravates lipopolysaccharide-induced acute lung injury by regulating the miR-98-5p\/TLR4 axis. J. Biochem. Mol. Toxicol., 2021,35(12): e22927.","DOI":"10.1002\/jbt.22927"},{"issue":"12","key":"10.1016\/j.intimp.2026.116484_bb0230","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/s41576-023-00611-y","article-title":"microRNAs in action: biogenesis, function and regulation","volume":"24","author":"Shang","year":"2023","journal-title":"Nat. Rev. Genet."},{"issue":"6","key":"10.1016\/j.intimp.2026.116484_bb0235","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/s41580-021-00354-w","article-title":"MicroRNA-mediated regulation of glucose and lipid metabolism","volume":"22","author":"Agbu","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.intimp.2026.116484_bb0240","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1172\/JCI27657","article-title":"Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system","volume":"116","author":"Mergia","year":"2006","journal-title":"J. Clin. Invest."},{"issue":"11","key":"10.1016\/j.intimp.2026.116484_bb0245","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1164\/rccm.201311-2037OC","article-title":"Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema","volume":"189","author":"Weissmann","year":"2014","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"8","key":"10.1016\/j.intimp.2026.116484_bb0250","doi-asserted-by":"crossref","first-page":"L569","DOI":"10.1152\/ajplung.00401.2012","article-title":"Soluble guanylate cyclase modulates alveolarization in the newborn lung","volume":"305","author":"Bachiller","year":"2013","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926003280?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926003280?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:13:32Z","timestamp":1790838812000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926003280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":50,"alternative-id":["S1567576926003280"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116484","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ASIC1a promotes alveolar epithelial apoptosis and acute lung injury through repression of the LncRNA00178\/miR-466b-3p\/Gucy1b1 ceRNA network","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116484","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116484"}}