{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T11:52:01Z","timestamp":1776167521578,"version":"3.50.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"publisher","award":["7212130"],"award-info":[{"award-number":["7212130"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172166"],"award-info":[{"award-number":["82172166"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.intimp.2026.116541","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T08:29:42Z","timestamp":1774254582000},"page":"116541","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Phenylephrine attenuates LPS-induced lung injury via Foxh1\/GSK-3\u03b2\/\u03b2-catenin-mediated alveolar epithelial cell differentiation in ARDS"],"prefix":"10.1016","volume":"177","author":[{"given":"Zhaojin","family":"Zeng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiyuan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhukai","family":"Cong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Senhao","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyun","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyuan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinggang","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2026.116541_bb0005","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0140-6736(21)00439-6","article-title":"Acute respiratory distress syndrome","volume":"398","author":"Meyer","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2026.116541_bb0010","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0140-6736(22)01485-4","article-title":"Acute Respiratory Distress Syndrome 2022 1 Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes","volume":"400","author":"Bos","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.intimp.2026.116541_bb0015","article-title":"Acute respiratory distress syndrome","volume":"387","author":"Wick","year":"2024","journal-title":"Bmj-Brit. Med. J."},{"key":"10.1016\/j.intimp.2026.116541_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112670","article-title":"Using the sympathetic system, beta blockers and alpha-2 agonists, to address acute respiratory distress syndrome","volume":"139","author":"Yin","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2026.116541_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1090773","article-title":"\u03b11-adrenoceptor stimulation ameliorates lipopolysaccharide-induced lung injury by inhibiting alveolar macrophage inflammatory responses through NF-\u03baB and ERK1\/2 pathway in ARDS","volume":"13","author":"Cong","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116541_bb0030","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/nature12930","article-title":"Alveolar progenitor and stem cells in lung development, renewal and cancer","volume":"507","author":"Desai","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2026.116541_bb0035","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22052566","article-title":"The history and mystery of alveolar epithelial type II cells: focus on their physiologic and pathologic role in lung","volume":"22","author":"Ruaro","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0040","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10753-022-01726-w","article-title":"The role of macrophages and alveolar epithelial cells in the development of ARDS","volume":"46","author":"Tao","year":"2023","journal-title":"Inflammation"},{"key":"10.1016\/j.intimp.2026.116541_bb0045","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1172\/JCI68782","article-title":"Type 2 alveolar cells are stem cells in adult lung","volume":"123","author":"Barkauskas","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2026.116541_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2024.03.010","article-title":"Tracing the origin of alveolar stem cells in lung repair and regeneration","volume":"187","author":"Liu","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2026.116541_bb0055","article-title":"Generation of alveolar epithelial type I cells from human pluripotent stem cells","volume":"201","author":"Burgess","year":"2020","journal-title":"Am J Resp Crit Care"},{"key":"10.1016\/j.intimp.2026.116541_bb0060","article-title":"Repair and regeneration of the alveolar epithelium in lung injury","volume":"38","author":"Wang","year":"2024","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2026.116541_bb0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21093188","article-title":"Mechanisms of ATII-to-ATI cell differentiation during lung regeneration","volume":"21","author":"Aspal","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0070","first-page":"1495","article-title":"Human FOX gene family (review)","volume":"25","author":"Katoh","year":"2004","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.intimp.2026.116541_bb0075","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1038\/sj.emboj.7601753","article-title":"Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development","volume":"26","author":"Izzi","year":"2007","journal-title":"EMBO J."},{"key":"10.1016\/j.intimp.2026.116541_bb0080","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1158\/2159-8290.CD-18-1391","article-title":"A gain-of-function p53-mutant oncogene promotes cell fate plasticity and myeloid Leukemia through the pluripotency factor FOXH1","volume":"9","author":"Loizou","year":"2019","journal-title":"Cancer Discov."},{"key":"10.1016\/j.intimp.2026.116541_bb0085","article-title":"FOXH1 is regulated by NANOG and LIN28 for early-stage reprogramming","volume":"9","author":"Wang","year":"2019","journal-title":"Sci Rep-Uk"},{"key":"10.1016\/j.intimp.2026.116541_bb0090","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms4678","article-title":"Induction of pluripotency in human somatic cells via a transient state resembling primitive streak- like mesendoderm","volume":"5","author":"Takahashi","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116541_bb0095","article-title":"Wnt\/\u03b2-catenin signalling: function, biological mechanisms, and therapeutic opportunities","volume":"7","author":"Liu","year":"2022","journal-title":"Signal Transduct Tar"},{"key":"10.1016\/j.intimp.2026.116541_bb0100","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.cell.2012.05.012","article-title":"Wnt\/\u03b2-catenin Signaling and disease","volume":"149","author":"Clevers","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2026.116541_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24087299","article-title":"PGE2 produced by exogenous MSCs promotes immunoregulation in ARDS induced by highly pathogenic influenza a through activation of the Wnt-\u03b2-catenin Signaling pathway","volume":"24","author":"Yudhawati","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0110","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-023-03474-6","article-title":"Effect of hCMSCs and liraglutide combination in ALI through cAMP\/PKAc\/\u03b2-catenin signaling pathway (retraction of vol 11, art no 2, 2020)","volume":"14","author":"Feng","year":"2023","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.intimp.2026.116541_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2022.116132","article-title":"The myosin II inhibitor, blebbistatin, ameliorates pulmonary endothelial barrier dysfunction in acute lung injury induced by LPS via NMMHC IIA\/Wnt5a\/\u03b2-catenin pathway","volume":"450","author":"Zhang","year":"2022","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.intimp.2026.116541_bb0120","article-title":"GSK-3\u03b2 in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer","volume":"1867","author":"Lin","year":"2020","journal-title":"Biochimica et Biophysica Acta (BBA)"},{"key":"10.1016\/j.intimp.2026.116541_bb0125","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202402470R","article-title":"Targeting GSK-3\u03b2 for adipose dysfunction and cardiovascular complications of metabolic disease: an entangled WNT\/\u03b2-catenin question","volume":"38","author":"Alotaiq","year":"2024","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2026.116541_bb0130","doi-asserted-by":"crossref","first-page":"18444","DOI":"10.1074\/jbc.RA118.003688","article-title":"Activin\/Smad2 and Wnt\/\u03b2-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells","volume":"293","author":"Xu","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.intimp.2026.116541_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2020.101314","article-title":"Foxh1\/nodal defines context-specific direct maternal Wnt\/\u03b2-catenin target gene regulation in early development","volume":"23","author":"Afouda","year":"2020","journal-title":"Iscience"},{"key":"10.1016\/j.intimp.2026.116541_bb0140","article-title":"FOXH1 promotes lung cancer progression by activating the Wnt\/\u03b2-catenin signaling pathway","volume":"21","author":"Zhang","year":"2021","journal-title":"Cancer Cell Int."},{"key":"10.1016\/j.intimp.2026.116541_bb0145","doi-asserted-by":"crossref","unstructured":"G. Matute-Bello, G. Downey, B.B. Moore, S.D. Groshong, M.A. Matthay, A.S. Slutsky, W.M. Kuebler, E.R. Chilvers, C. Doerschuck, D. Dreyfuss, P.Q. Eichacker, J.A. Elias, A. Esteban, N.D. Ferguson, R.W. Glenny, P. Henson, J.A. Lorente, T.R. Martin, J.A. Nick, P. Rimensberger, S. Uhlig, T. Van Der Poll, J. Villar, A.L.I.A.S. Grp, An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals, Am J Resp Cell Mol, 44 (2011) 725\u2013738.","DOI":"10.1165\/rcmb.2009-0210ST"},{"key":"10.1016\/j.intimp.2026.116541_bb0150","article-title":"Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation","volume":"2","author":"Chen","year":"2021","journal-title":"Star Protoc"},{"key":"10.1016\/j.intimp.2026.116541_bb0155","doi-asserted-by":"crossref","DOI":"10.1007\/s00018-023-05099-7","article-title":"Wnt\/\u03b2-catenin-driven EMT regulation in human cancers","volume":"81","author":"Xue","year":"2024","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0160","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1124\/pharmrev.121.000356","article-title":"Inhaled \u03b22 adrenergic agonists and other cAMP- elevating agents: therapeutics for alveolar injury and acute respiratory disease Syndrome?","volume":"73","author":"Sriram","year":"2021","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.intimp.2026.116541_bb0165","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jacc.2021.07.003","article-title":"Metoprolol in critically ill patients with COVID-19","volume":"78","author":"Clemente-Morag\u00f3n","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.intimp.2026.116541_bb0170","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1097\/SHK.0000000000001590","article-title":"Superior effects of nebulized epinephrine to nebulized Albuterol and phenylephrine in burn and smoke inhalation-induced acute lung injury","volume":"54","author":"Fukuda","year":"2020","journal-title":"Shock"},{"key":"10.1016\/j.intimp.2026.116541_bb0175","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/jlb.61.6.689","article-title":"LPS-induced blood neutrophilia is inhibited by alpha(1)-adrenoceptor antagonists: a role for catecholamines","volume":"61","author":"Altenburg","year":"1997","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.intimp.2026.116541_bb0180","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0165-5728(00)00376-3","article-title":"A role for adrenoceptors in the regulation of pleural neutrophilia induced by LPS","volume":"111","author":"Altenburg","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.intimp.2026.116541_bb0185","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1093\/stmcls\/sxad074","article-title":"Mechanisms of alveolar type 2 epithelial cell death during acute lung injury","volume":"41","author":"Qi","year":"2023","journal-title":"Stem Cells"},{"key":"10.1016\/j.intimp.2026.116541_bb0190","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/ehf2.14982","article-title":"Biomarkers of lung congestion and injury in acute heart failure","volume":"12","author":"Guazzi","year":"2025","journal-title":"ESC Heart Fail."},{"key":"10.1016\/j.intimp.2026.116541_bb0195","doi-asserted-by":"crossref","first-page":"21213","DOI":"10.1021\/jacs.3c02815","article-title":"Selective water pore recognition and transport through self-assembled alkyl-ureido-Trianglamine artificial water channels","volume":"145","author":"Andrei","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.intimp.2026.116541_bb0200","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/978-94-024-1057-0_7","article-title":"Aquaporins in respiratory system","volume":"969","author":"Song","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.intimp.2026.116541_bb0205","doi-asserted-by":"crossref","first-page":"6073","DOI":"10.7150\/jca.98829","article-title":"Important functions and molecular mechanisms of aquaporins family on respiratory diseases: potential translational values","volume":"15","author":"Li","year":"2024","journal-title":"J. Cancer"},{"key":"10.1016\/j.intimp.2026.116541_bb0210","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-020-05525-2","article-title":"Bone marrow-derived mesenchymal stem cells attenuate pulmonary inflammation and lung damage caused by highly pathogenic avian influenza a\/H5N1 virus in BALB\/c mice","volume":"20","author":"Yudhawati","year":"2020","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.intimp.2026.116541_bb0215","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2020.00452","article-title":"Effects of different ligands in the notch signaling pathway on the proliferation and transdifferentiation of primary type II alveolar epithelial cells","volume":"8","author":"Liu","year":"2020","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.intimp.2026.116541_bb0220","doi-asserted-by":"crossref","DOI":"10.1186\/s12915-019-0683-z","article-title":"FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation","volume":"17","author":"Fischer","year":"2019","journal-title":"BMC Biol."},{"key":"10.1016\/j.intimp.2026.116541_bb0225","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.159331","article-title":"Hypercapnia alters stroma-derived Wnt production to limit \u03b2-catenin signaling and proliferation in AT2 cells","volume":"8","author":"Dada","year":"2023","journal-title":"JCI Insight."},{"key":"10.1016\/j.intimp.2026.116541_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.pupt.2023.102263","article-title":"IRE1\u03b1\/XBP-1 promotes \u03b2-catenin signaling activation of airway epithelium in lipopolysaccharide-induced acute lung injury","volume":"83","author":"Zhang","year":"2023","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.intimp.2026.116541_bb0235","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1007\/s10528-024-10872-9","article-title":"HTR3A promotes non-small cell lung cancer through the FOXH1\/Wnt3A signaling pathway","volume":"63","author":"Wu","year":"2024","journal-title":"Biochem. Genet."},{"key":"10.1016\/j.intimp.2026.116541_bb0240","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1042\/CS20245219","article-title":"Glycogen synthase kinase 3\u03b2: a key player in progressive chronic kidney disease","volume":"139","author":"Zhang","year":"2025","journal-title":"Clin. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0245","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20222429","article-title":"The Wnt\/\u03b2-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury","volume":"43","author":"Chen","year":"2023","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.intimp.2026.116541_bb0250","doi-asserted-by":"crossref","DOI":"10.4028\/b-7TThNX","article-title":"A natural small molecule mitigates kidney fibrosis by targeting Cdc42-mediated GSK-3\u03b2\/\u03b2-catenin signaling","volume":"11","author":"Hu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0255","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/JS9.0000000000002075","article-title":"Polydatin accelerates osteoporotic bone repair by inducing the osteogenesis-angiogenesis coupling of bone marrow mesenchymal stem cells via the PI3K\/AKT\/GSK-3\u03b2\/\u03b2-catenin pathway","volume":"111","author":"Zhou","year":"2025","journal-title":"Int. J. Surg."},{"key":"10.1016\/j.intimp.2026.116541_bb0260","article-title":"GART promotes the proliferation and migration of human non-small cell lung cancer cell lines A549 and H1299 by targeting PAICS-Akt-\u03b2-catenin pathway","volume":"15","author":"Chen","year":"2025","journal-title":"Front. Oncol."},{"key":"10.1016\/j.intimp.2026.116541_bb0265","doi-asserted-by":"crossref","DOI":"10.1007\/s00432-024-05853-9","article-title":"KIS, a target of SOX4, regulates the ID1-mediated enhancement of \u03b2-catenin to facilitate lung adenocarcinoma cell proliferation and metastasis","volume":"150","author":"Chang","year":"2024","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"10.1016\/j.intimp.2026.116541_bb0270","doi-asserted-by":"crossref","DOI":"10.1186\/s11658-024-00636-z","article-title":"Identification of zinc finger MIZ-type containing 2 as an oncoprotein enhancing NAD-dependent protein deacetylase sirtuin-1 deacetylase activity to regulate Wnt and hippo pathways in non-small-cell lung cancer","volume":"29","author":"Gan","year":"2024","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.intimp.2026.116541_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccell.2024.11.003","article-title":"Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity","volume":"43","author":"Qiu","year":"2025","journal-title":"Cancer Cell"},{"key":"10.1016\/j.intimp.2026.116541_bb0280","doi-asserted-by":"crossref","first-page":"5254","DOI":"10.7150\/ijbs.101507","article-title":"Amlexanox enforces osteogenic differentiation and bone homeostasis through inhibiting ubiquitin-dependent degradation of \u03b2-catenin","volume":"20","author":"He","year":"2024","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.intimp.2026.116541_bb0285","doi-asserted-by":"crossref","first-page":"H725","DOI":"10.1152\/ajpheart.00621.2020","article-title":"Cardiac \u03b11A-adrenergic receptors: emerging protective roles in cardiovascular diseases","volume":"320","author":"Zhang","year":"2021","journal-title":"Am. J. Physiol-Heart C"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926003863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926003863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:58:11Z","timestamp":1776164291000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926003863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":57,"alternative-id":["S1567576926003863"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116541","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phenylephrine attenuates LPS-induced lung injury via Foxh1\/GSK-3\u03b2\/\u03b2-catenin-mediated alveolar epithelial cell differentiation in ARDS","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116541","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116541"}}