{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:22:05Z","timestamp":1790770925255,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32360181"],"award-info":[{"award-number":["32360181"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.intimp.2026.116603","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T18:06:08Z","timestamp":1775585168000},"page":"116603","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12\u2013CXCR4 axis"],"prefix":"10.1016","volume":"179","author":[{"given":"Xiao","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyun","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqiong","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2026.116603_bb0005","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1055\/s-0043-1777759","article-title":"Obesity and miscarriage","volume":"41","author":"McLean","year":"2023","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0010","doi-asserted-by":"crossref","first-page":"R79","DOI":"10.1530\/REP-18-0583","article-title":"Obesity induces ovarian inflammation and reduces oocyte quality","volume":"158","author":"Alexandria P Snider","year":"2019","journal-title":"Reproduction"},{"key":"10.1016\/j.intimp.2026.116603_bb0015","doi-asserted-by":"crossref","DOI":"10.5812\/ijem.101776","article-title":"Potential adverse effects of female and male obesity on fertility: a narrative review","volume":"18","author":"Amiri","year":"2020","journal-title":"Int. J. Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2026.116603_bb0020","article-title":"Obesity and its impact on female reproductive health: unraveling the connections","volume":"14","author":"Zheng","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.intimp.2026.116603_bb0025","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-022-02672-y","article-title":"Obese visceral fat tissue inflammation: from protective to detrimental?","volume":"20","author":"Kolb","year":"2022","journal-title":"BMC Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0030","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.metabol.2012.08.012","article-title":"The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review","volume":"62","author":"Michalakis","year":"2013","journal-title":"Metabolism"},{"key":"10.1016\/j.intimp.2026.116603_bb0035","doi-asserted-by":"crossref","DOI":"10.3390\/nu15030611","article-title":"A multi-ingredient supplement protects against obesity and infertility in western diet-fed mice","volume":"15","author":"Nilsson","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.intimp.2026.116603_bb0040","doi-asserted-by":"crossref","first-page":"R219","DOI":"10.1530\/REP-14-0435","article-title":"Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome","volume":"149","author":"Spritzer","year":"2015","journal-title":"Reprod. (Camb. Engl.)."},{"key":"10.1016\/j.intimp.2026.116603_bb0045","first-page":"145","article-title":"A novel marker for prediabetic conditions: uric acid-to-HDL cholesterol ratio","volume":"125","author":"Balci","year":"2024","journal-title":"Bratisl. Lek. Listy"},{"key":"10.1016\/j.intimp.2026.116603_bb0050","article-title":"Waist-to-height ratio as a novel marker of metabolic syndrome in patients with type 2 diabetes mellitus","volume":"2","author":"Basaran","year":"2025","journal-title":"Explor. Endocr. Metab. Dis."},{"key":"10.1016\/j.intimp.2026.116603_bb0055","doi-asserted-by":"crossref","DOI":"10.4239\/wjd.v16.i7.105233","article-title":"Exploring the link: hemogram-derived markers in type 2 diabetes mellitus and its complications","volume":"16","author":"Aktas","year":"2025","journal-title":"World J. Diabetes"},{"key":"10.1016\/j.intimp.2026.116603_bb0060","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/03007995.2025.2463952","article-title":"The systemic immune inflammation index is a reliable and novel risk factor for metabolic dysfunction-associated fatty liver disease","volume":"41","author":"Kosekli","year":"2025","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.intimp.2026.116603_bb0065","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/postmj\/qgaf181","article-title":"Systemic inflammatory markers and epicardial fat volume as predictors of cardiometabolic risk in type 2 diabetes","volume":"102","author":"Cosgun","year":"2025","journal-title":"Postgrad. Med. J."},{"key":"10.1016\/j.intimp.2026.116603_bb0070","first-page":"111","article-title":"Evaluation of the effects of intermittent fasting on clinical and laboratory parameters in metabolic syndrome","volume":"8","author":"Duman","year":"2025","journal-title":"Exp Biomed Res"},{"key":"10.1016\/j.intimp.2026.116603_bb0075","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.3724\/abbs.2023089","article-title":"Obesity-induced inflammatory miR-133a mediates apoptosis of granulosa cells and causes abnormal folliculogenesis","volume":"55","author":"Chen","year":"2023","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"10.1016\/j.intimp.2026.116603_bb0080","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abn4564","article-title":"Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary","volume":"8","author":"Umehara","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.intimp.2026.116603_bb0085","article-title":"High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures","volume":"22","author":"Liu","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0090","article-title":"The impact of mitochondrial dysfunction on ovarian aging","volume":"23","author":"Zhang","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0095","article-title":"Ferroptosis as a potential therapeutic target for obesity-related metabolic diseases","volume":"16","author":"Huang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.116603_bb0100","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.tem.2024.04.014","article-title":"Intermittent fasting influences immunity and metabolism","volume":"35","author":"Marko","year":"2024","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.intimp.2026.116603_bb0105","article-title":"Role of intermittent fasting in the management of prediabetes and type 2 diabetes mellitus","volume":"14","author":"Ojo","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.intimp.2026.116603_bb0110","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.freeradbiomed.2022.12.084","article-title":"Intermittent fasting reverses the declining quality of aged oocytes","volume":"195","author":"Li","year":"2023","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0115","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1007\/s13668-024-00569-1","article-title":"Effects of intermittent fasting on female reproductive function: a review of animal and human studies","volume":"13","author":"Mao","year":"2024","journal-title":"Curr. Nutr. Rep."},{"key":"10.1016\/j.intimp.2026.116603_bb0120","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1172\/JCI200420997","article-title":"Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis","volume":"114","author":"Phillips","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2026.116603_bb0125","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.imlet.2016.06.006","article-title":"CXCR4 signaling in health and disease","volume":"177","author":"Pozzobon","year":"2016","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.intimp.2026.116603_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101809","article-title":"CXCL12\/CXCR4: an amazing challenge and opportunity in the fight against fibrosis","volume":"83","author":"Wu","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.intimp.2026.116603_bb0135","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14092314","article-title":"CXCR4\/CXCL12 activities in the tumor microenvironment and implications for tumor immunotherapy","volume":"14","author":"Mezzapelle","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.intimp.2026.116603_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2019.00585","article-title":"The role of the CXCL12\/CXCR4\/ACKR3 axis in autoimmune diseases","volume":"10","author":"Garc\u00eda-Cuesta","year":"2019","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.intimp.2026.116603_bb0145","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1002\/med.22011","article-title":"CXCR4\/CXCL12 axis: \u201cold\u201d pathway as \u201cnovel\u201d target for anti-inflammatory drug discovery","volume":"44","author":"Lu","year":"2024","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.intimp.2026.116603_bb0150","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-54685-1","article-title":"Granzyme K+CD8+ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps","volume":"15","author":"Guo","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116603_bb0155","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.ard.2025.04.025","article-title":"Spatial multiomics decipher fibroblast-macrophage dynamics in systemic sclerosis","volume":"84","author":"Li","year":"2025","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.intimp.2026.116603_bb0160","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1007\/s13311-022-01194-y","article-title":"Regorafenib reverses temozolomide-induced CXCL12\/CXCR4 signaling and triggers apoptosis mechanism in glioblastoma","volume":"19","author":"Chiang","year":"2022","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.intimp.2026.116603_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.113707","article-title":"Isoferulic acid regulates CXCL12\/CXCR4-mediated apoptosis and autophagy in podocyte and mice with STZ-induced diabetic nephropathy","volume":"144","author":"Liu","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2026.116603_bb0170","article-title":"CREB1-driven CXCR4hi neutrophils promote skin inflammation in mouse models and human patients","volume":"14","author":"Chen","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116603_bb0175","doi-asserted-by":"crossref","first-page":"377","DOI":"10.2147\/JIR.S259633","article-title":"NLRP3 regulated CXCL12 expression in acute neutrophilic lung injury","volume":"13","author":"Peng","year":"2020","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.intimp.2026.116603_bb0180","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202205500","article-title":"Selective translation of maternal mRNA by eIF4E1B controls oocyte to embryo transition","volume":"10","author":"Guo","year":"2023","journal-title":"Adv. Sci."},{"key":"10.1016\/j.intimp.2026.116603_bb0185","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-45505-7","article-title":"The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12","volume":"15","author":"Mantonico","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116603_bb0190","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.550824","article-title":"\u03b2-arrestin1 and \u03b2-arrestin2 are required to support the activity of the CXCL12\/HMGB1 heterocomplex on CXCR4","volume":"11","author":"D\u2019Agostino","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116603_bb0195","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1084\/jem.20111739","article-title":"HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4","volume":"209","author":"Schiraldi","year":"2012","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0200","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nri.2017.10","article-title":"Neutrophils as protagonists and targets in chronic inflammation","volume":"17","author":"Soehnlein","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2026.116603_bb0205","doi-asserted-by":"crossref","first-page":"366","DOI":"10.7150\/ijms.80189","article-title":"Role of obesity in female reproduction","volume":"20","author":"Yong","year":"2023","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.intimp.2026.116603_bb0210","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.fertnstert.2017.01.017","article-title":"Obesity and female infertility: potential mediators of obesity\u2019s impact","volume":"107","author":"Broughton","year":"2017","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.intimp.2026.116603_bb0215","article-title":"Dysregulation of immune response in PCOS organ system","volume":"14","author":"Wang","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116603_bb0220","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1136\/gutjnl-2023-329998","article-title":"Timing of energy intake and the therapeutic potential of intermittent fasting and time-restricted eating in NAFLD","volume":"72","author":"Marjot","year":"2023","journal-title":"Gut"},{"key":"10.1016\/j.intimp.2026.116603_bb0225","article-title":"Intermittent fasting improves high-fat diet-induced obesity cardiomyopathy via alleviating lipid deposition and apoptosis and decreasing m6A methylation in the heart","volume":"14","author":"Xu","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.intimp.2026.116603_bb0230","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.freeradbiomed.2024.03.021","article-title":"Intermittent fasting improves the oocyte quality of obese mice through the regulation of maternal mRNA storage and translation by LSM14B","volume":"217","author":"Li","year":"2024","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103195","article-title":"Iron accumulation in ovarian microenvironment damages the local redox balance and oocyte quality in aging mice","volume":"73","author":"Chen","year":"2024","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2026.116603_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102684","article-title":"miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation","volume":"62","author":"Wang","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2026.116603_bb0245","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1146\/annurev-biochem-032620-104401","article-title":"Mitochondrial DNA release in innate immune signaling","volume":"92","author":"Newman","year":"2023","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.intimp.2026.116603_bb0250","article-title":"Both diet and gene mutation induced obesity affect oocyte quality in mice","volume":"6","author":"Hou","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2026.116603_bb0255","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/s41580-018-0093-z","article-title":"Adipogenesis and metabolic health","volume":"20","author":"Ghaben","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.intimp.2026.116603_bb0260","doi-asserted-by":"crossref","first-page":"C375","DOI":"10.1152\/ajpcell.00379.2020","article-title":"Adipose tissue inflammation and metabolic dysfunction in obesity","volume":"320","author":"Kawai","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.intimp.2026.116603_bb0265","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41423-021-00832-3","article-title":"Neutrophils in chronic inflammatory diseases","volume":"19","author":"Herrero-Cervera","year":"2022","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.intimp.2026.116603_bb0270","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/jcp.25855","article-title":"Adipocytes properties and crosstalk with immune system in obesity-related inflammation","volume":"233","author":"Maurizi","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.intimp.2026.116603_bb0275","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.lfs.2017.05.001","article-title":"Role of SDF-1\/CXCR4 and cytokines in the development of ovary injury in chemotherapy drug induced premature ovarian failure mice","volume":"179","author":"Luo","year":"2017","journal-title":"Life Sci."},{"key":"10.1016\/j.intimp.2026.116603_bb0280","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s43032-021-00791-0","article-title":"CXCL12 may drive inflammatory potential in the ovine corpus luteum during implantation","volume":"29","author":"S.Z","year":"2022","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.intimp.2026.116603_bb0285","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-023-01183-6","article-title":"Intra-ovarian inflammatory states and their associations with embryo quality in normal-BMI PCOS patients undergoing IVF treatment","volume":"22","author":"Shang","year":"2024","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.intimp.2026.116603_bb0290","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1055\/s-0032-1328878","article-title":"Obesity and PCOS: implications for diagnosis and treatment","volume":"30","author":"Legro","year":"2012","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0295","article-title":"Characteristics and possible mechanisms of metabolic disorder in overweight women with polycystic ovary syndrome","volume":"13","author":"Yu","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.intimp.2026.116603_bb0300","doi-asserted-by":"crossref","first-page":"335","DOI":"10.5582\/bst.2023.01207","article-title":"Influence of intermittent fasting on autophagy in the liver","volume":"17","author":"Ma","year":"2023","journal-title":"Biosci. Trends"},{"key":"10.1016\/j.intimp.2026.116603_bb0305","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-023-04772-6","article-title":"The role of AMPK in macrophage metabolism, function and polarisation","volume":"21","author":"Cui","year":"2023","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.intimp.2026.116603_bb0310","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/cr.2011.13","article-title":"NF-\u03bab in immunobiology","volume":"21","author":"Hayden","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.intimp.2026.116603_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2024.109871","article-title":"Intermittent fasting along with hydroalcoholic extract of Centella-asiatica ameliorates sub-acute hypoxia-induced ischemic stroke in adult zebrafish","volume":"279","author":"Bindal","year":"2024","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.intimp.2026.116603_bb0320","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.2337\/db19-0829","article-title":"Endothelial overexpression of metallothionein prevents diabetes-induced impairment in ischemia angiogenesis through preservation of HIF-1\u03b1\/SDF-1\/VEGF signaling in endothelial progenitor cells","volume":"69","author":"Wang","year":"2020","journal-title":"Diabetes"},{"key":"10.1016\/j.intimp.2026.116603_bb0325","doi-asserted-by":"crossref","first-page":"5306","DOI":"10.1182\/blood-2010-05-284414","article-title":"Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists","volume":"116","author":"Mandawat","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2026.116603_bb0330","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202503534R","article-title":"Intermittent fasting enhances genome integrity and cytoprotective pathways via (BHB) \u03b2-hydroxybutyrate signaling and chromatin remodeling","volume":"40","author":"Parnas","year":"2026","journal-title":"FASEB J."},{"key":"10.1016\/j.intimp.2026.116603_bb0335","doi-asserted-by":"crossref","DOI":"10.1186\/s13048-025-01724-0","article-title":"New perspectives on polycystic ovary syndrome: hypothalamic-sympathetic-adipose tissue interaction","volume":"18","author":"Zhang","year":"2025","journal-title":"J. Ovarian Res."},{"key":"10.1016\/j.intimp.2026.116603_bb0340","doi-asserted-by":"crossref","DOI":"10.1186\/1477-7827-3-44","article-title":"Rats with steroid-induced polycystic ovaries develop hypertension and increased sympathetic nervous system activity","volume":"3","author":"Stener-Victorin","year":"2005","journal-title":"Reprod. Biol. Endocrinol."}],"updated-by":[{"DOI":"10.1016\/j.intimp.2026.117030","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000}},{"DOI":"10.1016\/j.intimp.2026.117030","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000}}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004480?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004480?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:08:57Z","timestamp":1786651737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926004480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":68,"alternative-id":["S1567576926004480"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116603","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intermittent fasting attenuates ovarian chronic inflammation in obese mice by inhibiting the CXCL12\u2013CXCR4 axis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116603","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116603"}}