{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T04:53:17Z","timestamp":1789275197065,"version":"build-2803163510"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Zhejiang Province Natural Science Foundation","doi-asserted-by":"publisher","award":["LQ22H090010"],"award-info":[{"award-number":["LQ22H090010"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007194","name":"Wenzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["Y20240105"],"award-info":[{"award-number":["Y20240105"]}],"id":[{"id":"10.13039\/501100007194","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007835","name":"Wenzhou Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U24A20697"],"award-info":[{"award-number":["U24A20697"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271345"],"award-info":[{"award-number":["82271345"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.intimp.2026.116613","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T13:16:29Z","timestamp":1775567789000},"page":"116613","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Anacardic acid mitigates traumatic brain injury-induced inflammatory damage: involvement of TLR4\/MyD88\/NF-\u03baB pathway regulation and inhibition of P300 HAT activity on NF-\u03baB acetylation"],"prefix":"10.1016","volume":"179","author":[{"given":"Chenguang","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junnan","family":"Ru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoran","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuqi","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiwei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunlin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qichuan","family":"Zhuge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7482","key":"10.1016\/j.intimp.2026.116613_bb0005","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature12808","article-title":"Transcranial amelioration of inflammation and cell death after brain injury","volume":"505","author":"Roth","year":"2014","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0010","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12974-016-0555-1","article-title":"The effect of concomitant peripheral injury on traumatic brain injury pathobiology and outcome","volume":"13","author":"McDonald","year":"2016","journal-title":"J. Neuroinflammation"},{"issue":"4 Suppl","key":"10.1016\/j.intimp.2026.116613_bb0015","doi-asserted-by":"crossref","first-page":"S112","DOI":"10.1016\/j.amepre.2008.01.011","article-title":"The challenges of assessing the incidence of inflicted traumatic brain injury: a world perspective","volume":"34","author":"Runyan","year":"2008","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.intimp.2026.116613_bb0020","doi-asserted-by":"crossref","first-page":"1582182","DOI":"10.1155\/2017\/1582182","article-title":"Rehabilitation treatment and progress of traumatic brain injury dysfunction","volume":"2017","author":"Dang","year":"2017","journal-title":"Neural Plast."},{"key":"10.1016\/j.intimp.2026.116613_bb0025","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.biomaterials.2017.04.014","article-title":"Neural repair by NT3-chitosan via enhancement of endogenous neurogenesis after adult focal aspiration brain injury","volume":"140","author":"Hao","year":"2017","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.intimp.2026.116613_bb0030","doi-asserted-by":"crossref","DOI":"10.1111\/cns.70568","article-title":"Microglia in post-traumatic brain injury (TBI) cognitive impairment: from pathological changes to therapeutic approaches","volume":"31","author":"Li","year":"2025","journal-title":"CNS Neurosci. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0035","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12974-019-1471-y","article-title":"A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury","volume":"16","author":"Kuwar","year":"2019","journal-title":"J. Neuroinflammation"},{"issue":"17","key":"10.1016\/j.intimp.2026.116613_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21176204","article-title":"The role of NLRP3 inflammasome in the pathogenesis of traumatic brain injury","volume":"21","author":"Irrera","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6301","key":"10.1016\/j.intimp.2026.116613_bb0045","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1126\/science.aaf6260","article-title":"Inflammatory neuroprotection following traumatic brain injury","volume":"353","author":"Russo","year":"2016","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.intimp.2026.116613_bb0050","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci7080100","article-title":"Autonomic dysfunction after mild traumatic brain injury","volume":"7","author":"Esterov","year":"2017","journal-title":"Brain Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0055","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s12974-016-0738-9","article-title":"Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation","volume":"13","author":"Corrigan","year":"2016","journal-title":"J. Neuroinflammation"},{"issue":"2","key":"10.1016\/j.intimp.2026.116613_bb0060","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/sj.mp.4000227","article-title":"Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue","volume":"2","author":"Morganti-Kossman","year":"1997","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.intimp.2026.116613_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176436","article-title":"Chitosan revokes controlled-cortical impact generated neurological aberrations in circadian disrupted mice via TLR4-NLRP3 axis","volume":"969","author":"Bazaz","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.intimp.2026.116613_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2025.178477","article-title":"Nose-to-brain delivery of quercetin-loaded chitosan nanoparticles improves post-traumatic stress disorder-like phenotypes in mice","volume":"1012","author":"Bazaz","year":"2026","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116613_bb0075","doi-asserted-by":"crossref","first-page":"921","DOI":"10.3892\/ijmm.2016.2495","article-title":"Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4\/NF-kappaB signaling pathway in experimental traumatic brain injury","volume":"37","author":"Feng","year":"2016","journal-title":"Int. J. Mol. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0080","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11011-024-01517-2","article-title":"Chitosan lactate improves repeated closed head injury-generated motor and neurological dysfunctions in mice by impacting microbiota gut-brain axis","volume":"40","author":"Bazaz","year":"2025","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.intimp.2026.116613_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156580","article-title":"Intestinal 8 gingerol attenuates TBI-induced neuroinflammation by inhibiting microglia NLRP3 inflammasome activation in a PINK1\/Parkin-dependent manner","volume":"140","author":"Tang","year":"2025","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0090","doi-asserted-by":"crossref","first-page":"2394352","DOI":"10.1080\/17590914.2024.2394352","article-title":"Implications of iron in ferroptosis, necroptosis, and pyroptosis as potential players in TBI morbidity and mortality","volume":"16","author":"Nolt","year":"2024","journal-title":"ASN Neuro"},{"issue":"6","key":"10.1016\/j.intimp.2026.116613_bb0095","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.neuron.2015.02.041","article-title":"Traumatic brain injury and the neuronal microenvironment: a potential role for neuropathological mechanotransduction","volume":"85","author":"Hemphill","year":"2015","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0100","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.3892\/ijo.2013.1763","article-title":"Anacardic acid induces mitochondrial-mediated apoptosis in the a549 human lung adenocarcinoma cells","volume":"42","author":"Seong","year":"2013","journal-title":"Int. J. Oncol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116613_bb0105","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1124\/jpet.111.181891","article-title":"Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src\/FAK\/rho GTPases signaling pathway","volume":"339","author":"Wu","year":"2011","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0110","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13567-019-0621-7","article-title":"Effect of anacardic acid against echinococcosis through inhibition of VEGF-induced angiogenesis","volume":"50","author":"Yuan","year":"2019","journal-title":"Vet. Res."},{"key":"10.1016\/j.intimp.2026.116613_bb0115","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.cyto.2018.09.008","article-title":"Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model","volume":"111","author":"Yang","year":"2018","journal-title":"Cytokine"},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0120","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.3892\/or.2017.5841","article-title":"Anacardic acid induces cell apoptosis of prostatic cancer through autophagy by ER stress\/DAPK3\/Akt signaling pathway","volume":"38","author":"Tan","year":"2017","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.intimp.2026.116613_bb0125","first-page":"653","article-title":"Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines - in vitro studies","volume":"9","author":"Legut","year":"2014","journal-title":"Int. J. Nanomedicine"},{"issue":"21","key":"10.1016\/j.intimp.2026.116613_bb0130","doi-asserted-by":"crossref","first-page":"19134","DOI":"10.1074\/jbc.M301580200","article-title":"Small molecule modulators of histone acetyltransferase p300","volume":"278","author":"Balasubramanyam","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.intimp.2026.116613_bb0135","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.1182\/blood-2007-10-117994","volume":"111","author":"Sung","year":"2008","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.intimp.2026.116613_bb0140","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jdiacomp.2016.08.001","article-title":"Imbalance between HDAC and HAT activities drives aberrant STAT1\/MyD88 expression in macrophages from type 1 diabetic mice","volume":"31","author":"Filgueiras","year":"2017","journal-title":"J. Diabetes Complications"},{"issue":"4","key":"10.1016\/j.intimp.2026.116613_bb0145","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1002\/ptr.8164","article-title":"Critical review on anti-inflammation effects of saponins and their molecular mechanisms","volume":"38","author":"Wijesekara","year":"2024","journal-title":"Phytother. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.116613_bb0150","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1039\/C6MB00692B","article-title":"Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice","volume":"13","author":"Peng","year":"2017","journal-title":"Mol. Biosyst."},{"issue":"11","key":"10.1016\/j.intimp.2026.116613_bb0155","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.7150\/ijbs.42197","article-title":"Histone acetyltransferase (HAT) P300\/CBP inhibitors induce synthetic lethality in PTEN-deficient colorectal cancer cells through destabilizing AKT","volume":"16","author":"Liu","year":"2020","journal-title":"Int. J. Biol. Sci."},{"issue":"12","key":"10.1016\/j.intimp.2026.116613_bb0160","article-title":"Melatonin reduces NLRP3 inflammasome activation by increasing alpha7 nAChR-mediated autophagic flux","volume":"9","author":"Farre-Alins","year":"2020","journal-title":"Antioxidants (Basel)"},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0165","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s13287-019-1210-4","article-title":"Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury","volume":"10","author":"Hu","year":"2019","journal-title":"Stem Cell Res. Ther."},{"issue":"5","key":"10.1016\/j.intimp.2026.116613_bb0170","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s11011-017-9991-6","article-title":"DRalpha1-MOG-35-55 treatment reduces lesion volumes and improves neurological deficits after traumatic brain injury","volume":"32","author":"Yang","year":"2017","journal-title":"Metab. Brain Dis."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0175","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","article-title":"Reversible middle cerebral artery occlusion without craniectomy in rats","volume":"20","author":"Longa","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.intimp.2026.116613_bb0180","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1750-1326-3-19","article-title":"In vivo silencing of alpha-synuclein using naked siRNA","volume":"3","author":"Lewis","year":"2008","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.intimp.2026.116613_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2202-14-1","article-title":"PI3K\/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus","volume":"14","author":"Zhu","year":"2013","journal-title":"BMC Neurosci."},{"issue":"12","key":"10.1016\/j.intimp.2026.116613_bb0190","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.7150\/ijbs.45467","article-title":"Role of pyroptosis in traumatic brain and spinal cord injuries","volume":"16","author":"Hu","year":"2020","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0195","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s12974-018-1083-y","article-title":"Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo","volume":"15","author":"Liu","year":"2018","journal-title":"J. Neuroinflammation"},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0200","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nrneurol.2017.13","article-title":"The far-reaching scope of neuroinflammation after traumatic brain injury","volume":"13","author":"Simon","year":"2017","journal-title":"Nat. Rev. Neurol."},{"issue":"14","key":"10.1016\/j.intimp.2026.116613_bb0205","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1089\/neu.2017.5530","article-title":"Microglial inflammasome activation in penetrating ballistic-like brain injury","volume":"35","author":"Lee","year":"2018","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.intimp.2026.116613_bb0210","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12974-019-1423-6","article-title":"The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury","volume":"16","author":"Lee","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.intimp.2026.116613_bb0215","article-title":"NF-kappaB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct. Target. Ther."},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0220","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/s41419-020-2399-y","article-title":"Life, death, and autophagy in cancer: NF-kappaB turns up everywhere","volume":"11","author":"Verzella","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.intimp.2026.116613_bb0225","doi-asserted-by":"crossref","first-page":"690","DOI":"10.3389\/fnins.2018.00690","article-title":"Inhibition of NF-kappaB signaling pathway by resveratrol improves spinal cord injury","volume":"12","author":"Xu","year":"2018","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.intimp.2026.116613_bb0230","doi-asserted-by":"crossref","unstructured":"J. Zhang, X. Wang, V. Vikash, Q. Ye, D. Wu, Y. Liu, W. Dong, ROS and ROS-mediated cellular signaling, Oxid. Med. Cell. Longev. 2016 (2016) 4350965.","DOI":"10.1155\/2016\/4350965"},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0235","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.cjtee.2018.02.003","article-title":"Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities","volume":"21","author":"Xiong","year":"2018","journal-title":"Chin. J. Traumatol."},{"issue":"3","key":"10.1016\/j.intimp.2026.116613_bb0240","doi-asserted-by":"crossref","first-page":"216","DOI":"10.2174\/1871527319666200918145903","article-title":"Targeting microglial polarization to improve TBI outcomes","volume":"20","author":"Nathalie","year":"2021","journal-title":"CNS Neurol. Disord. Drug Targets"},{"key":"10.1016\/j.intimp.2026.116613_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2023.114568","article-title":"Anacardic acid improves neurological deficits in traumatic brain injury by anti-ferroptosis and anti-inflammation","volume":"370","author":"Liu","year":"2023","journal-title":"Exp. Neurol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116613_bb0250","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1007\/s11033-020-05324-7","article-title":"The protective effect of uric acid in reducing TLR4\/NF-kappaB activation through the inhibition of HMGB1 acetylation in a model of ischemia-reperfusion injury in vitro","volume":"47","author":"Cheng","year":"2020","journal-title":"Mol. Biol. Rep."},{"issue":"6","key":"10.1016\/j.intimp.2026.116613_bb0255","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.4103\/NRR.NRR-D-25-00073","article-title":"Nlrp3 inflammasome: a link between systemic infection and Alzheimer\u2019s disease","volume":"21","author":"Barichello","year":"2026","journal-title":"Neural Regen. Res."},{"issue":"10","key":"10.1016\/j.intimp.2026.116613_bb0260","doi-asserted-by":"crossref","first-page":"5667","DOI":"10.1007\/s10787-025-01926-4","article-title":"Targeting NLRP3 inflammasome with curcumin: mechanisms and therapeutic promise in chronic inflammation","volume":"33","author":"Pandey","year":"2025","journal-title":"Inflammopharmacology"},{"issue":"4","key":"10.1016\/j.intimp.2026.116613_bb0265","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41423-025-01275-w","article-title":"NLRP3 inflammasome in neuroinflammation and central nervous system diseases","volume":"22","author":"Xu","year":"2025","journal-title":"Cell. Mol. Immunol."},{"issue":"17","key":"10.1016\/j.intimp.2026.116613_bb0270","doi-asserted-by":"crossref","first-page":"7603","DOI":"10.1523\/JNEUROSCI.4181-12.2013","article-title":"Nuclear factor kappaB-dependent histone acetylation is specifically involved in persistent forms of memory","volume":"33","author":"Federman","year":"2013","journal-title":"J. Neurosci."},{"issue":"8","key":"10.1016\/j.intimp.2026.116613_bb0275","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202152649","article-title":"Dynamic chromatin association of IkappaBalpha is regulated by acetylation and cleavage of histone h4","volume":"22","author":"Marruecos","year":"2021","journal-title":"EMBO Rep."},{"issue":"2","key":"10.1016\/j.intimp.2026.116613_bb0280","doi-asserted-by":"crossref","first-page":"R509","DOI":"10.1152\/ajpregu.00858.2009","article-title":"Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle","volume":"299","author":"Alamdari","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"6","key":"10.1016\/j.intimp.2026.116613_bb0285","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1111\/j.1751-1097.2008.00385.x","article-title":"Mechanism of UV-induced IkappaBalpha-independent activation of NF-kappaB","volume":"84","author":"Laszlo","year":"2008","journal-title":"Photochem. Photobiol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116613_bb0290","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1128\/MCB.26.2.457-471.2006","article-title":"IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA\/p65 by p300","volume":"26","author":"Hoberg","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.intimp.2026.116613_bb0295","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-2164-11-22","article-title":"Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression","volume":"11","author":"Rothgiesser","year":"2010","journal-title":"BMC Genomics"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004583?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004583?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T15:15:02Z","timestamp":1777130102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926004583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":59,"alternative-id":["S1567576926004583"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116613","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anacardic acid mitigates traumatic brain injury-induced inflammatory damage: involvement of TLR4\/MyD88\/NF-\u03baB pathway regulation and inhibition of P300 HAT activity on NF-\u03baB acetylation","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116613","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116613"}}