{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:20:37Z","timestamp":1791390037166,"version":"4.3.3"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["HKZYY-2025-12"],"award-info":[{"award-number":["HKZYY-2025-12"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82274408"],"award-info":[{"award-number":["82274408"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574906"],"award-info":[{"award-number":["82574906"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020447","name":"Huangshan University","doi-asserted-by":"publisher","award":["XCZXZD2403"],"award-info":[{"award-number":["XCZXZD2403"]}],"id":[{"id":"10.13039\/501100020447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010876","name":"Shanghai University of Traditional Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010876","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.intimp.2026.116651","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T12:25:33Z","timestamp":1777119933000},"page":"116651","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Ethyl caffeate reprograms macrophage immunometabolism via the SIRT3\u2013FOXO3A\u2013AKT axis to enhance host defense against Candida auris"],"prefix":"10.1016","volume":"180","author":[{"given":"Xiaohui","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilang","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanjiayi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenqin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhouyu","family":"Nie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaomiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongkai","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenglin","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruilian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongbing","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0005","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0010","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13756-016-0132-5","article-title":"First hospital outbreak of the globally emerging Candida auris in a European hospital","volume":"5","author":"Schelenz","year":"2016","journal-title":"Antimicrob. Resist. Infect. Control"},{"issue":"2","key":"10.1016\/j.intimp.2026.116651_bb0015","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2017","journal-title":"Clin. Infect. Dis."},{"issue":"13","key":"10.1016\/j.intimp.2026.116651_bb0020","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1089\/ars.2020.8028","article-title":"Targeting evolutionary conserved oxidative stress and immunometabolic pathways for the treatment of respiratory infectious diseases","volume":"32","author":"Erlich","year":"2020","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.intimp.2026.116651_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.734229","article-title":"Reactive oxygen species in macrophages: sources and targets","volume":"12","author":"Canton","year":"2021","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116651_bb0030","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.3390\/jcm9051397","article-title":"Systemic redox imbalance in patients with chronic granulomatous disease","volume":"9","author":"Heropolitanska-Pliszka","year":"2020","journal-title":"J. Clin. Med."},{"issue":"35","key":"10.1016\/j.intimp.2026.116651_bb0035","doi-asserted-by":"crossref","first-page":"36998","DOI":"10.18632\/oncotarget.6076","article-title":"Activation of sirtuin 1\/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage","volume":"6","author":"Li","year":"2015","journal-title":"Oncotarget"},{"issue":"18","key":"10.1016\/j.intimp.2026.116651_bb0040","doi-asserted-by":"crossref","first-page":"8315","DOI":"10.7150\/thno.45922","article-title":"Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target","volume":"10","author":"Zhang","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.intimp.2026.116651_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101799","article-title":"Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications","volume":"37","author":"Kang","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.intimp.2026.116651_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123481","article-title":"Idebenone improves mitochondrial respiratory activity and attenuates oxidative damage via the SIRT3-SOD2 pathway in a prion disease cell model","volume":"366-367","author":"Sun","year":"2025","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.intimp.2026.116651_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurot.2025.e00525","article-title":"Mitochondrial dysfunction in Alzheimer's disease: Guiding the path to targeted therapies","volume":"22","author":"McGill Percy","year":"2025","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.intimp.2026.116651_bb0060","article-title":"Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology","volume":"16","author":"Zhang","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.intimp.2026.116651_bb0065","first-page":"2758","article-title":"Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice","volume":"119","author":"Sundaresan","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.intimp.2026.116651_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123849","article-title":"CXCL10 modulates airway inflammation in asthma via Sirt3-dependent macrophage homeostasis","volume":"379","author":"Ding","year":"2025","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.intimp.2026.116651_bb0075","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/sj.bjp.0706343","article-title":"Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin","volume":"146","author":"Chiang","year":"2005","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.intimp.2026.116651_bb0080","doi-asserted-by":"crossref","first-page":"5567174","DOI":"10.1155\/2022\/5567174","article-title":"ROS-Induced Oxidative Damage and Mitochondrial Dysfunction Mediated by Inhibition of SIRT3 in Cultured Cochlear Cells","volume":"2022","author":"Zhang","year":"2022","journal-title":"Neural Plast."},{"key":"10.1016\/j.intimp.2026.116651_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114508","article-title":"Ethyl caffeate inhibits macrophage polarization via SIRT1\/NF-\u03baB to attenuate traumatic heterotopic ossification in mice","volume":"161","author":"Wang","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"30","key":"10.1016\/j.intimp.2026.116651_bb0090","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202301615","article-title":"Supramolecular nano-assembly of caffeate-strengthened phenylboronic ester with multistep ROS scavenging ability for targeted therapy of acute kidney injury","volume":"12","author":"Jia","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.intimp.2026.116651_bb0095","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.3389\/fimmu.2018.01573","article-title":"Candida albicans-induced NETosis is independent of peptidylarginine deiminase 4","volume":"9","author":"Guiducci","year":"2018","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0100","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.1038\/s41467-022-31201-x","article-title":"Innate immune responses against the fungal pathogen Candida auris","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.intimp.2026.116651_bb0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112522","article-title":"Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response","volume":"42","author":"Weerasinghe","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.intimp.2026.116651_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107407","article-title":"Suppression of ZEB1 by Ethyl caffeate attenuates renal fibrosis via switching glycolytic reprogramming","volume":"209","author":"Hu","year":"2024","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.intimp.2026.116651_bb0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1172\/jci.insight.93156","article-title":"Immunity against fungi","volume":"2","author":"Lionakis","year":"2017","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.intimp.2026.116651_bb0120","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1080\/15548627.2019.1569916","article-title":"The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion","volume":"15","author":"Xia","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/j.intimp.2026.116651_bb0125","article-title":"Macrophage mediated immunomodulation during cryptococcus pulmonary infection","volume":"12","author":"Wang","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116651_bb0130","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.4049\/jimmunol.1402376","article-title":"Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence","volume":"194","author":"Davis","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2026.116651_bb0135","series-title":"Plasma Membrane Damage by Environmental Materials Enhances Cell-Cell Fusion and Impairs Immune Functions of Macrophages. bioRxiv","author":"Wu","year":"2025"},{"issue":"8","key":"10.1016\/j.intimp.2026.116651_bb0140","doi-asserted-by":"crossref","first-page":"782","DOI":"10.3390\/jof9080782","article-title":"Anticytokine autoantibodies and fungal infections","volume":"9","author":"Kappagoda","year":"2023","journal-title":"J. Fungi (Basel)"},{"key":"10.1016\/j.intimp.2026.116651_bb0145","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.3389\/fimmu.2019.02821","article-title":"Bacterial manipulation of autophagic responses in infection and inflammation","volume":"10","author":"Jiao","year":"2019","journal-title":"Front. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2026.116651_bb0150","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/tra.12199","article-title":"PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages","volume":"15","author":"Kim","year":"2014","journal-title":"Traffic"},{"issue":"7","key":"10.1016\/j.intimp.2026.116651_bb0155","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1038\/s42255-022-00605-w","article-title":"TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages","volume":"4","author":"Schuster","year":"2022","journal-title":"Nat. Metab."},{"issue":"7","key":"10.1016\/j.intimp.2026.116651_bb0160","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1161\/CIRCRESAHA.123.323160","article-title":"SIRT3 regulates clearance of apoptotic cardiomyocytes by deacetylating frataxin","volume":"133","author":"Gao","year":"2023","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.116651_bb0165","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202406159","article-title":"Subversion of the host endocytic pathway by Legionella pneumophila-mediated ubiquitination of Rab5","volume":"224","author":"Tanaka","year":"2025","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0170","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1080\/21505594.2020.1809961","article-title":"Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis","volume":"11","author":"Kim","year":"2020","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0175","doi-asserted-by":"crossref","first-page":"5817","DOI":"10.1038\/s41467-024-50100-x","article-title":"Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing","volume":"15","author":"Reedy","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116651_bb0180","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.semcdb.2018.03.003","article-title":"Pattern recognition receptors in fungal immunity","volume":"89","author":"Patin","year":"2019","journal-title":"Semin. Cell Dev. Biol."},{"issue":"7344","key":"10.1016\/j.intimp.2026.116651_bb0185","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1038\/nature09973","article-title":"TLR signalling augments macrophage bactericidal activity through mitochondrial ROS","volume":"472","author":"West","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.intimp.2026.116651_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.coi.2023.102366","article-title":"Mitochondrial reactive oxygen species: double agents in Mycobacterium tuberculosis infection","volume":"84","author":"Ellzey","year":"2023","journal-title":"Curr. Opin. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116651_bb0195","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/cdd.2017.144","article-title":"SIRT3\/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress","volume":"25","author":"Gao","year":"2018","journal-title":"Cell Death Differ."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0200","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00018-025-05865-9","article-title":"Neutrophilic granule protein promotes lipopolysaccharide-induced iNOS\/NO expression via JAK2\/STAT1 signaling pathway and augments bacteria clearance of macrophages","volume":"82","author":"Tian","year":"2025","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0205","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.celrep.2019.06.018","article-title":"Nitric oxide modulates metabolic remodeling in inflammatory macrophages through TCA cycle regulation and itaconate accumulation","volume":"28","author":"Bailey","year":"2019","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.intimp.2026.116651_bb0210","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cell.2017.04.001","article-title":"AKT\/PKB signaling: navigating the network","volume":"169","author":"Manning","year":"2017","journal-title":"Cell"},{"issue":"18","key":"10.1016\/j.intimp.2026.116651_bb0215","doi-asserted-by":"crossref","first-page":"9623","DOI":"10.7150\/thno.116712","article-title":"ASIC1a induces excessive mitophagy and PANoptosis of chondrocyte by the inhibition of SIRT3 mitochondrial translocation","volume":"15","author":"Zai","year":"2025","journal-title":"Theranostics"},{"key":"10.1016\/j.intimp.2026.116651_bb0220","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.freeradbiomed.2013.05.002","article-title":"SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage","volume":"63","author":"Tseng","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.intimp.2026.116651_bb0225","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1161\/CIRCRESAHA.119.315767","article-title":"Mitochondrial deacetylase Sirt3 reduces vascular dysfunction and hypertension while Sirt3 depletion in essential hypertension is linked to vascular inflammation and oxidative stress","volume":"126","author":"Dikalova","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.intimp.2026.116651_bb0230","article-title":"Sirtuins as potential therapeutic targets for Hepatitis B virus infection","volume":"8","author":"Kong","year":"2021","journal-title":"Front. Med. (Lausanne)"},{"key":"10.1016\/j.intimp.2026.116651_bb0235","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.3389\/fimmu.2020.01790","article-title":"Host-directed therapy in tuberculosis: targeting host metabolism","volume":"11","author":"Kim","year":"2020","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116651_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2024.109643","article-title":"Redox signaling and skeletal muscle adaptation during aerobic exercise","volume":"27","author":"Zhou","year":"2024","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0245","doi-asserted-by":"crossref","first-page":"29566","DOI":"10.1038\/s41598-025-15165-8","article-title":"Curcumin preserves bone health compromised by diabetes by inhibiting osteoporosis through regulation of the SIRT3\/FoxO3a signalling pathway","volume":"15","author":"Mohammad","year":"2025","journal-title":"Sci. Rep."},{"issue":"13","key":"10.1016\/j.intimp.2026.116651_bb0250","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1111\/bph.70022","article-title":"Ginsenoside Rh1 mitigates mitochondrial dysfunction induced by myocardial ischaemia through its novel role as a sirtuin 3 activator","volume":"182","author":"Gong","year":"2025","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0255","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.gendis.2023.01.002","article-title":"Overcoming adaptive resistance in AML by synergistically targeting FOXO3A-GNG7-mTOR axis with FOXO3A inhibitor Gardenoside and rapamycin","volume":"11","author":"Chen","year":"2024","journal-title":"Genes Dis."},{"issue":"21","key":"10.1016\/j.intimp.2026.116651_bb0260","doi-asserted-by":"crossref","first-page":"11810","DOI":"10.3390\/ijms222111810","article-title":"Deacetylation of transcription factors in carcinogenesis","volume":"22","author":"Halasa","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116651_bb0265","doi-asserted-by":"crossref","first-page":"6656","DOI":"10.1038\/ncomms7656","article-title":"Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3","volume":"6","author":"Pillai","year":"2015","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0270","doi-asserted-by":"crossref","first-page":"13281","DOI":"10.1038\/s41598-024-64350-8","article-title":"FOXO3a\/PI3K\/Akt pathway participates in the ROS- induced apoptosis triggered by \u03b1-ZEL and \u03b2-ZEL","volume":"14","author":"Habrowska-G\u00f3rczy\u0144ska","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.intimp.2026.116651_bb0275","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.769617","article-title":"Neuroprotective potential of Tamarillo (Cyphomandra betacea) epicarp extracts obtained by sustainable extraction process","volume":"8","author":"Su\u00e1rez-Montenegro","year":"2021","journal-title":"Front. Nutr."},{"issue":"22","key":"10.1016\/j.intimp.2026.116651_bb0280","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1161\/CIRCULATIONAHA.105.598409","article-title":"Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy","volume":"113","author":"Kim","year":"2006","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.intimp.2026.116651_bb0285","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13059-019-1651-1","article-title":"Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in natural killer cells","volume":"20","author":"Sharma","year":"2019","journal-title":"Genome Biol."},{"issue":"5","key":"10.1016\/j.intimp.2026.116651_bb0290","doi-asserted-by":"crossref","first-page":"708","DOI":"10.3390\/cells12050699","article-title":"The protein network in subcutaneous fat biopsies from patients with al amyloidosis: more than diagnosis?","volume":"12","author":"Di Silvestre","year":"2023","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.intimp.2026.116651_bb0295","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1097\/JS9.0000000000002394","article-title":"Exploring the toxicological network in diabetic microvascular disease","volume":"111","author":"Song","year":"2025","journal-title":"Int. J. Surg."},{"issue":"3","key":"10.1016\/j.intimp.2026.116651_bb0300","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/s12276-022-00745-9","article-title":"HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3","volume":"54","author":"Hu","year":"2022","journal-title":"Exp. Mol. Med."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004960?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926004960?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T15:26:13Z","timestamp":1783178773000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926004960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":60,"alternative-id":["S1567576926004960"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116651","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ethyl caffeate reprograms macrophage immunometabolism via the SIRT3\u2013FOXO3A\u2013AKT axis to enhance host defense against Candida auris","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116651","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116651"}}