{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:08:42Z","timestamp":1789243722575,"version":"build-2803163510"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013017","name":"Vanderbilt University Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013017","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.intimp.2026.116745","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T20:14:27Z","timestamp":1778184867000},"page":"116745","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Inhibition of SUMOylation by anacardic acid inhibits adaptive immunity and the development of EAE"],"prefix":"10.1016","volume":"182","author":[{"given":"Kwang","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5sa","family":"Ljunggren-Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medha","family":"Yarlagadda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Vergne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subramaniam","family":"Sriram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0005","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1742-7843.2011.00833.x","article-title":"Emerging roles of anacardic acid and its derivatives: a pharmacological overview","volume":"110","author":"Hemshekhar","year":"2012","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"35","key":"10.1016\/j.intimp.2026.116745_bb0010","doi-asserted-by":"crossref","first-page":"21527","DOI":"10.1073\/pnas.2006566117","article-title":"Anacardic acid induces IL-33 and promotes remyelination in CNS","volume":"117","author":"Ljunggren-Rose","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.intimp.2026.116745_bb0015","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1021\/jf048184e","article-title":"Lipoxygenase inhibitory activity of anacardic acids","volume":"53","author":"Ha","year":"2005","journal-title":"J. Agric. Food Chem."},{"issue":"7","key":"10.1016\/j.intimp.2026.116745_bb0020","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/j.celrep.2015.10.001","article-title":"Global reprogramming of host SUMOylation during influenza virus infection","volume":"13","author":"Domingues","year":"2015","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.intimp.2026.116745_bb0025","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/nrmicro3015","article-title":"Interplay between viruses and host sumoylation pathways","volume":"11","author":"Everett","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.intimp.2026.116745_bb0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.cytogfr.2016.04.003","article-title":"The implication of SUMO in intrinsic and innate immunity","volume":"29","author":"Hannoun","year":"2016","journal-title":"Cytokine Growth Factor Rev."},{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0035","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/ni.3342","article-title":"Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing","volume":"17","author":"Decque","year":"2016","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2026.116745_bb0040","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev-biochem-061909-093311","article-title":"Sumoylation: a regulatory protein modification in health and disease","volume":"82","author":"Flotho","year":"2013","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.intimp.2026.116745_bb0045","doi-asserted-by":"crossref","unstructured":"Dohmen, R.J., SUMO protein modification. Biochim. Biophys. Acta, 2004. 1695(1\u20133): p. 113\u201331.","DOI":"10.1016\/j.bbamcr.2004.09.021"},{"issue":"3","key":"10.1016\/j.intimp.2026.116745_bb0050","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/35056591","article-title":"SUMO, ubiquitin\u2019s mysterious cousin","volume":"2","author":"Muller","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0055","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1042\/BJ20100158","article-title":"Mechanisms, regulation and consequences of protein SUMOylation","volume":"428","author":"Wilkinson","year":"2010","journal-title":"Biochem. J."},{"issue":"12","key":"10.1016\/j.intimp.2026.116745_bb0060","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/nrm2293","article-title":"Concepts in sumoylation: a decade on","volume":"8","author":"Geiss-Friedlander","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"7","key":"10.1016\/j.intimp.2026.116745_bb0065","doi-asserted-by":"crossref","first-page":"440","DOI":"10.4161\/epi.4.7.9807","article-title":"SUMO engages multiple corepressors to regulate chromatin structure and transcription","volume":"4","author":"Ouyang","year":"2009","journal-title":"Epigenetics"},{"issue":"12","key":"10.1016\/j.intimp.2026.116745_bb0070","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/nrm3011","article-title":"The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition","volume":"11","author":"Gareau","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116745_bb0075","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.brainresrev.2010.04.002","article-title":"Targets and consequences of protein SUMOylation in neurons","volume":"64","author":"Wilkinson","year":"2010","journal-title":"Brain Res. Rev."},{"issue":"12","key":"10.1016\/j.intimp.2026.116745_bb0080","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/nrm3478","article-title":"Function and regulation of SUMO proteases","volume":"13","author":"Hickey","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.intimp.2026.116745_bb0085","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1146\/annurev.biochem.73.011303.074118","article-title":"Protein modification by SUMO","volume":"73","author":"Johnson","year":"2004","journal-title":"Annu. Rev. Biochem."},{"issue":"4","key":"10.1016\/j.intimp.2026.116745_bb0090","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1097-2765(04)00060-7","article-title":"SUMO promotes HDAC-mediated transcriptional repression","volume":"13","author":"Yang","year":"2004","journal-title":"Mol. Cell"},{"issue":"7","key":"10.1016\/j.intimp.2026.116745_bb0095","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1128\/MCB.25.7.2688-2697.2005","article-title":"Ikaros SUMOylation: switching out of repression","volume":"25","author":"Gomez-del Arco","year":"2005","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116745_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.devcel.2012.11.020","article-title":"SUMO: a multifaceted modifier of chromatin structure and function","volume":"24","author":"Cubenas-Potts","year":"2013","journal-title":"Dev. Cell"},{"key":"10.1016\/j.intimp.2026.116745_bb0105","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bbrc.2022.04.115","article-title":"Treatment with anacardic acid modulates dendritic cell activation and alleviates the disease development of autoimmune neuroinflammation in mice","volume":"613","author":"Gao","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0110","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.chembiol.2009.01.009","article-title":"Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate","volume":"16","author":"Fukuda","year":"2009","journal-title":"Chem. Biol."},{"issue":"21","key":"10.1016\/j.intimp.2026.116745_bb0115","doi-asserted-by":"crossref","first-page":"35103","DOI":"10.18632\/oncotarget.16626","article-title":"Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-kappaB activity","volume":"8","author":"Hamdoun","year":"2017","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.intimp.2026.116745_bb0120","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0092-8674(03)00895-X","article-title":"Sequential modification of NEMO\/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress","volume":"115","author":"Huang","year":"2003","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.intimp.2026.116745_bb0125","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/s41577-025-01155-4","article-title":"Immune regulation by the SUMO family","volume":"25","author":"Tharuka","year":"2025","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0130","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/bpa.12454","article-title":"Multiple sclerosis animal models: a clinical and histopathological perspective","volume":"27","author":"Kipp","year":"2017","journal-title":"Brain Pathol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116745_bb0135","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.msard.2011.09.002","article-title":"Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyond","volume":"1","author":"Kipp","year":"2012","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.intimp.2026.116745_bb0140","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.mrgentox.2014.11.008","article-title":"Genotoxic and cytostatic effects of 6-pentadecyl salicylic anacardic acid in transformed cell lines and peripheral blood mononuclear cells","volume":"777","author":"Alam-Escamilla","year":"2015","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"issue":"2","key":"10.1016\/j.intimp.2026.116745_bb0145","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1097-2765(00)80133-1","article-title":"SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation","volume":"2","author":"Desterro","year":"1998","journal-title":"Mol. Cell"},{"issue":"12","key":"10.1016\/j.intimp.2026.116745_bb0150","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0051672","article-title":"Heterologous SUMO-2\/3-ubiquitin chains optimize IkappaBalpha degradation and NF-kappaB activity","volume":"7","author":"Aillet","year":"2012","journal-title":"PloS One"},{"issue":"46","key":"10.1016\/j.intimp.2026.116745_bb0155","doi-asserted-by":"crossref","first-page":"55511","DOI":"10.1021\/acsomega.5c06377","article-title":"Targeting SUMOylation with Anacardic acid derivatives: novel insights into EGF pathway dysregulation in Cancer using an in silico approach","volume":"10","author":"Padmakumar","year":"2025","journal-title":"ACS Omega"},{"issue":"11","key":"10.1016\/j.intimp.2026.116745_bb0160","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/nri2423","article-title":"New regulators of NF-kappaB in inflammation","volume":"8","author":"Ghosh","year":"2008","journal-title":"Nat. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2026.116745_bb0165","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.cell.2008.01.020","article-title":"Shared principles in NF-kappaB signaling","volume":"132","author":"Hayden","year":"2008","journal-title":"Cell"},{"issue":"49","key":"10.1016\/j.intimp.2026.116745_bb0170","doi-asserted-by":"crossref","first-page":"6867","DOI":"10.1038\/sj.onc.1203219","article-title":"How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex","volume":"18","author":"Karin","year":"1999","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.intimp.2026.116745_bb0175","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0962-8924(00)01729-3","article-title":"The IKK complex: an integrator of all signals that activate NF-kappaB?","volume":"10","author":"Israel","year":"2000","journal-title":"Trends Cell Biol."},{"issue":"6699","key":"10.1016\/j.intimp.2026.116745_bb0180","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/26261","article-title":"IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex","volume":"395","author":"Rothwarf","year":"1998","journal-title":"Nature"},{"issue":"19","key":"10.1016\/j.intimp.2026.116745_bb0185","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1038\/emboj.2009.241","article-title":"NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain","volume":"28","author":"Laplantine","year":"2009","journal-title":"EMBO J."},{"issue":"6","key":"10.1016\/j.intimp.2026.116745_bb0190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003480","article-title":"Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6","volume":"9","author":"Liu","year":"2013","journal-title":"PLoS Pathog."},{"issue":"10","key":"10.1016\/j.intimp.2026.116745_bb0195","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.1182\/blood-2007-10-117994","volume":"111","author":"Sung","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2026.116745_bb0200","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.681057","article-title":"SUMO and SUMOylation pathway at the forefront of host immune response","volume":"9","author":"K","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"39","key":"10.1016\/j.intimp.2026.116745_bb0205","doi-asserted-by":"crossref","first-page":"37297","DOI":"10.1074\/jbc.M303389200","article-title":"A role for NF-kappaB essential modifier\/IkappaB kinase-gamma (NEMO\/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha","volume":"278","author":"Tang","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.intimp.2026.116745_bb0210","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.1091\/mbc.e05-06-0536","article-title":"SUMO-1 modification alters ADAR1 editing activity","volume":"16","author":"Desterro","year":"2005","journal-title":"Mol. Biol. Cell"},{"issue":"5","key":"10.1016\/j.intimp.2026.116745_bb0215","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S1074-7613(00)00070-4","article-title":"Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12","volume":"13","author":"Oppmann","year":"2000","journal-title":"Immunity"},{"issue":"4","key":"10.1016\/j.intimp.2026.116745_bb0220","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1002\/eji.200425842","article-title":"Native myelin oligodendrocyte glycoprotein promotes severe chronic neurological disease and demyelination in Biozzi ABH mice","volume":"35","author":"Smith","year":"2005","journal-title":"Eur. J. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2026.116745_bb0225","doi-asserted-by":"crossref","first-page":"8066","DOI":"10.4049\/jimmunol.180.12.8066","article-title":"Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell lines","volume":"180","author":"Lees","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2026.116745_bb0230","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2147\/JIR.S6375","article-title":"Current perspectives on the role of IL-17 in autoimmune disease","volume":"3","author":"Yamada","year":"2010","journal-title":"J. Inflamm. Res."},{"issue":"1","key":"10.1016\/j.intimp.2026.116745_bb0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12016-025-09042-5","article-title":"The role of IL-17 in systemic autoinflammatory diseases: mechanisms and therapeutic perspectives","volume":"68","author":"Zhang","year":"2025","journal-title":"Clin Rev Allergy Immunol"},{"issue":"21","key":"10.1016\/j.intimp.2026.116745_bb0240","article-title":"Reframing immune-mediated inflammatory diseases. Reply","volume":"385","author":"Schett","year":"2021","journal-title":"N. Engl. J. Med."},{"issue":"8","key":"10.1016\/j.intimp.2026.116745_bb0245","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/s41577-024-01008-6","article-title":"Strategies for targeting cytokines in inflammatory bowel disease","volume":"24","author":"Neurath","year":"2024","journal-title":"Nat. Rev. Immunol."},{"issue":"7","key":"10.1016\/j.intimp.2026.116745_bb0250","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41575-023-00768-1","article-title":"IL-12 and IL-23 pathway inhibition in inflammatory bowel disease","volume":"20","author":"Verstockt","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"14","key":"10.1016\/j.intimp.2026.116745_bb0255","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21145164","article-title":"Small molecule NF-kappaB pathway inhibitors in clinic","volume":"21","author":"Ramadass","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116745_bb0260","first-page":"245","article-title":"Inhibition of NF-kappaB signaling as a strategy in disease therapy","volume":"349","author":"Gilmore","year":"2011","journal-title":"Curr. Top. Microbiol. Immunol."},{"issue":"10\u221212","key":"10.1016\/j.intimp.2026.116745_bb0265","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.bbagrm.2010.05.004","article-title":"Inhibiting NF-kappaB activation by small molecules as a therapeutic strategy","volume":"1799","author":"Gupta","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"issue":"18","key":"10.1016\/j.intimp.2026.116745_bb0270","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.135935","article-title":"Increased SUMO-activating enzyme SAE1\/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes","volume":"5","author":"Wang","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.intimp.2026.116745_bb0275","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2019.05.006","article-title":"The role of protein SUMOylation in rheumatoid arthritis","volume":"102","author":"Dehnavi","year":"2019","journal-title":"J. Autoimmun."},{"issue":"11","key":"10.1016\/j.intimp.2026.116745_bb0280","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.it.2021.09.005","article-title":"RORgammat protein modifications and IL-17-mediated inflammation","volume":"42","author":"Kumar","year":"2021","journal-title":"Trends Immunol."}],"updated-by":[{"DOI":"10.1016\/j.intimp.2026.116886","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T00:00:00Z","timestamp":1779494400000}},{"DOI":"10.1016\/j.intimp.2026.116886","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000}}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926005916?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926005916?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:03:52Z","timestamp":1789243432000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926005916"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":56,"alternative-id":["S1567576926005916"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116745","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of SUMOylation by anacardic acid inhibits adaptive immunity and the development of EAE","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116745","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116745"}}