{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:08:16Z","timestamp":1789243696500,"version":"build-2803163510"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.intimp.2026.116836","type":"journal-article","created":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T12:07:38Z","timestamp":1779019658000},"page":"116836","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Recombinant humanized type III collagen attenuates recurrent spontaneous abortion by regulating stromal cell decidualization and reinforcing protective immune microenvironment at the maternal\u2013fetal interface"],"prefix":"10.1016","volume":"182","author":[{"given":"Zhiyong","family":"Dong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingcong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiashuo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaibin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.intimp.2026.116836_bb0005","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.fertnstert.2019.11.025","article-title":"Practice Committee of the American Society for reproductive medicine. Electronic address: asrm@asrm.org. Definitions of infertility and recurrent pregnancy loss: a committee opinion","volume":"113","year":"2020","journal-title":"Fertil. Steril."},{"issue":"11","key":"10.1016\/j.intimp.2026.116836_bb0010","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13125","article-title":"Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion","volume":"54","author":"Du","year":"2021","journal-title":"Cell Prolif."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0015","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1038\/s41467-021-23827-0","article-title":"Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk","volume":"12","author":"Wang","year":"2021","journal-title":"Nat. Commun."},{"issue":"7","key":"10.1016\/j.intimp.2026.116836_bb0020","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1093\/humrep\/des102","article-title":"Unexplained recurrent miscarriage: how can we explain it?","volume":"27","author":"Saravelos","year":"2012","journal-title":"Hum. Reprod."},{"issue":"10285","key":"10.1016\/j.intimp.2026.116836_bb0025","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/S0140-6736(21)00681-4","article-title":"Recurrent miscarriage: evidence to accelerate action","volume":"397","author":"Coomarasamy","year":"2021","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.intimp.2026.116836_bb0030","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13859","article-title":"Maternal-fetal immunity and recurrent spontaneous abortion","volume":"91","author":"Yao","year":"2024","journal-title":"Am. J. Reprod. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2026.116836_bb0035","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/rmb2.12088","article-title":"Decidualization of the human endometrium","volume":"17","author":"Okada","year":"2018","journal-title":"Reprod Med Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0040","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/humrep\/deac240","article-title":"Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage","volume":"38","author":"Bao","year":"2023","journal-title":"Hum. Reprod."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0045","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s42825-022-00087-2","article-title":"The role of extracellular matrix on unfavorable maternal\u2013fetal interface: focusing on the function of collagen in human fertility","volume":"4","author":"Liu","year":"2022","journal-title":"J. Leather Sci. Eng."},{"issue":"12","key":"10.1016\/j.intimp.2026.116836_bb0050","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.7150\/ijbs.45586","article-title":"Collagen at the maternal-fetal interface in human pregnancy","volume":"16","author":"Shi","year":"2020","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0055","article-title":"Involvement of matrix metalloproteinases and their inhibitors in endometrial extracellular matrix turnover in Chlamydia trachomatis-infected recurrent spontaneous aborters","volume":"75","author":"Singh","year":"2017","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.intimp.2026.116836_bb0060","doi-asserted-by":"crossref","DOI":"10.1093\/rb\/rbad033","article-title":"Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation","volume":"10","author":"You","year":"2023","journal-title":"Regen. Biomater."},{"issue":"Pt 2","key":"10.1016\/j.intimp.2026.116836_bb0065","article-title":"Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17\/Treg imbalance","volume":"276","author":"Wang","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"4","key":"10.1016\/j.intimp.2026.116836_bb0070","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.bbrc.2018.12.018","article-title":"Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity","volume":"508","author":"Hua","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2026.116836_bb0075","first-page":"154","article-title":"The biological effect of recombinant humanized collagen on damaged skin induced by UV-photoaging: an in vivo study","volume":"11","author":"Wang","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.intimp.2026.116836_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2021.121055","article-title":"A tailored extracellular matrix (ECM) - mimetic coating for cardiovascular stents by stepwise assembly of hyaluronic acid and recombinant human type III collagen","volume":"276","author":"Yang","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.intimp.2026.116836_bb0085","doi-asserted-by":"crossref","first-page":"rbad055","DOI":"10.1093\/rb\/rbad055","article-title":"An extracellular matrix-mimetic coating with dual bionics for cardiovascular stents","volume":"10","author":"Chen","year":"2023","journal-title":"Regen Biomater."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0090","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s42825-022-00103-5","article-title":"Characterization of recombinant humanized collagen type III and its influence on cell behavior and phenotype","volume":"4","author":"Wang","year":"2022","journal-title":"J. Leather Sci. Eng."},{"key":"10.1016\/j.intimp.2026.116836_bb0095","doi-asserted-by":"crossref","DOI":"10.1093\/rb\/rbad089","article-title":"The influence of tag sequence on recombinant humanized collagen (rhCol) and the evaluation of rhCol on Schwann cell behaviors","volume":"10","author":"Bai","year":"2023","journal-title":"Regen. Biomater."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0100","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/jocd.15942","article-title":"Combination of fractional carbon dioxide laser with recombinant human collagen in periocular skin rejuvenation","volume":"23","author":"Wu","year":"2024","journal-title":"J. Cosmet. Dermatol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0105","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/s41467-024-44902-2","article-title":"A drug-free cardiovascular stent functionalized with tailored collagen supports in-situ healing of vascular tissues","volume":"15","author":"Wu","year":"2024","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.intimp.2026.116836_bb0110","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1021\/acsbiomaterials.9b01649","article-title":"Intravaginal Administration of Human Type III collagen-derived biomaterial with high cell-adhesion activity to treat vaginal atrophy in rats","volume":"6","author":"You","year":"2020","journal-title":"ACS Biomater Sci. Eng."},{"key":"10.1016\/j.intimp.2026.116836_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2022.112715","article-title":"Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats","volume":"134","author":"Li","year":"2022","journal-title":"Biomater. Adv."},{"issue":"6019","key":"10.1016\/j.intimp.2026.116836_bb0120","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1126\/science.1197454","article-title":"The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2","volume":"331","author":"Li","year":"2011","journal-title":"Science"},{"issue":"20","key":"10.1016\/j.intimp.2026.116836_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2023.08.020","article-title":"Spatiotemporal insight into early pregnancy governed by immune-featured stromal cells","volume":"186","author":"Yang","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2026.116836_bb0130","series-title":"The Guide to Investigation of Mouse Pregnancy","first-page":"125","article-title":"Decidualization and endometrial extracellular matrix remodeling","author":"Favaro","year":"2014"},{"issue":"6","key":"10.1016\/j.intimp.2026.116836_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.immuni.2017.11.018","article-title":"Natural killer cells promote Fetal development through the secretion of growth-promoting factors","volume":"47","author":"Fu","year":"2017","journal-title":"Immunity"},{"issue":"9","key":"10.1016\/j.intimp.2026.116836_bb0140","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1080\/15548627.2020.1833515","article-title":"Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence","volume":"17","author":"Lu","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.intimp.2026.116836_bb0145","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8689436","article-title":"Human decidual stromal cells as a component of the implantation niche and a modulator of maternal immunity","volume":"2016","author":"Vinketova","year":"2016","journal-title":"J. Pregnancy"},{"issue":"12","key":"10.1016\/j.intimp.2026.116836_bb0150","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1007\/s10815-022-02637-3","article-title":"Glucose and fatty acids catabolism during in vitro decidualization of human endometrial stromal cells","volume":"39","author":"Citrinovitz","year":"2022","journal-title":"J. Assist. Reprod. Genet."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0155","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1186\/s12964-024-01763-y","article-title":"Metabolic reprogramming and heterogeneity during the decidualization process of endometrial stromal cells","volume":"22","author":"Jia","year":"2024","journal-title":"Cell Commun. Signal"},{"issue":"12","key":"10.1016\/j.intimp.2026.116836_bb0160","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202402627","article-title":"Mitochondria remodeling during endometrial stromal cell decidualization","volume":"7","author":"Dalla Torre","year":"2024","journal-title":"Life Sci Alliance."},{"key":"10.1016\/j.intimp.2026.116836_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2025.154069","article-title":"Cadmium induces spontaneous abortion by impairing endometrial stromal cell decidualization","volume":"511","author":"Zhang","year":"2025","journal-title":"Toxicology"},{"issue":"5","key":"10.1016\/j.intimp.2026.116836_bb0170","doi-asserted-by":"crossref","first-page":"339","DOI":"10.3390\/metabo15050339","article-title":"Cadmium exposure disrupts uterine energy metabolism and coagulation homeostasis during labor in Institute of Cancer Research mice: insights from transcriptomic analysis","volume":"15","author":"Wang","year":"2025","journal-title":"Metabolites"},{"issue":"9","key":"10.1016\/j.intimp.2026.116836_bb0175","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.3390\/ijms26094066","article-title":"Gender-dependent effect of progesterone on the expression of metallothionein genes in rat inguinal adipose tissue","volume":"26","author":"Szrok-Jurga","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.intimp.2026.116836_bb0180","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1002\/jcp.26067","article-title":"Ptn functions downstream of C\/EBP\u03b2 to mediate the effects of cAMP on uterine stromal cell differentiation through targeting Hand2 in response to progesterone","volume":"233","author":"Yu","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.intimp.2026.116836_bb0185","article-title":"Deficiency of RAR\u03b1 suppresses decidualization via downregulating CEBPB transcription in women with recurrent implantation failure","volume":"13","author":"Huang","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"5","key":"10.1016\/j.intimp.2026.116836_bb0190","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/s41577-019-0139-2","article-title":"Immunometabolism and natural killer cell responses","volume":"19","author":"O\u2019Brien","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.intimp.2026.116836_bb0195","article-title":"Role of decidual natural killer cells in human pregnancy and related pregnancy complications","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0200","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s13287-024-03854-6","article-title":"Deciphering decidual deficiencies in recurrent spontaneous abortion and the therapeutic potential of mesenchymal stem cells at single-cell resolution","volume":"15","author":"Jin","year":"2024","journal-title":"Stem Cell Res. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0205","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1038\/s41467-023-42990-0","article-title":"IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy","volume":"14","author":"Han","year":"2023","journal-title":"Nat. Commun."},{"issue":"7731","key":"10.1016\/j.intimp.2026.116836_bb0210","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41586-018-0698-6","article-title":"Single-cell reconstruction of the early maternal-fetal interface in humans","volume":"563","author":"Vento-Tormo","year":"2018","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.intimp.2026.116836_bb0215","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1530\/REP-17-0782","article-title":"Role of osteopontin in decidualization and pregnancy success","volume":"155","author":"Wang","year":"2018","journal-title":"Reproduction"},{"issue":"4","key":"10.1016\/j.intimp.2026.116836_bb0220","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1093\/biolre\/ioab125","article-title":"SPP1 expression in the mouse uterus and placenta: implications for implantation\u2020","volume":"105","author":"Kramer","year":"2021","journal-title":"Biol. Reprod."},{"issue":"7","key":"10.1016\/j.intimp.2026.116836_bb0225","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1038\/s41590-024-01861-6","article-title":"Eomes expression identifies the early bone marrow precursor to classical NK cells","volume":"25","author":"Liang","year":"2024","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.intimp.2026.116836_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2015.00646","article-title":"Unique Eomes(+) NK cell subsets are present in uterus and decidua during early pregnancy","volume":"6","author":"Montaldo","year":"2016","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2026.116836_bb0235","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1038\/s41423-021-00739-z","article-title":"Biology and pathology of the uterine microenvironment and its natural killer cells","volume":"18","author":"Wang","year":"2021","journal-title":"Cell. Mol. Immunol."},{"issue":"1","key":"10.1016\/j.intimp.2026.116836_bb0240","doi-asserted-by":"crossref","first-page":"4492","DOI":"10.1038\/s41467-018-06918-3","article-title":"Molecular definition of group 1 innate lymphoid cells in the mouse uterus","volume":"9","author":"Filipovic","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.intimp.2026.116836_bb0245","doi-asserted-by":"crossref","first-page":"1610891","DOI":"10.3389\/fimmu.2025.1610891","article-title":"Decidual macrophage subsets and polarization puzzle during the human early pregnancy","volume":"16","author":"Liu","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116836_bb0250","doi-asserted-by":"crossref","first-page":"792","DOI":"10.3389\/fimmu.2019.00792","article-title":"Macrophage polarization in physiological and pathological pregnancy","volume":"10","author":"Yao","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.116836_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103486","article-title":"Abnormal ciliogenesis in decidual stromal cells in recurrent miscarriage","volume":"150","author":"Hassan","year":"2022","journal-title":"J. Reprod. Immunol."},{"issue":"12","key":"10.1016\/j.intimp.2026.116836_bb0260","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1093\/humrep\/deac229","article-title":"Basigin is necessary for normal decidualization of human uterine stromal cells","volume":"37","author":"Yang","year":"2022","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.intimp.2026.116836_bb0265","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/biolre\/ioab109","article-title":"Loss of basigin expression in uterine cells leads to subfertility in female mice\u2020","volume":"105","author":"Li","year":"2021","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.intimp.2026.116836_bb0270","doi-asserted-by":"crossref","first-page":"C604","DOI":"10.1152\/ajpcell.00735.2024","article-title":"CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy","volume":"328","author":"Zhu","year":"2025","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"7","key":"10.1016\/j.intimp.2026.116836_bb0275","doi-asserted-by":"crossref","first-page":"6170","DOI":"10.3390\/ijms24076170","article-title":"The interplay between integrins and immune cells as a regulator in Cancer immunology","volume":"24","author":"Zhang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.116836_bb0280","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.647358","article-title":"Natural killer cell integrins and their functions in tissue residency","volume":"12","author":"Shannon","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2026.116836_bb0285","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.cell.2020.05.003","article-title":"The physiology, pathology, and potential therapeutic applications of the TREM2 Signaling pathway","volume":"181","author":"Deczkowska","year":"2020","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.intimp.2026.116836_bb0290","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.7150\/ijbs.91519","article-title":"TREM2 promotes macrophage polarization from M1 to M2 and suppresses osteoarthritis through the NF-\u03baB\/CXCL3 axis","volume":"20","author":"Fang","year":"2024","journal-title":"Int. J. Biol. Sci."},{"issue":"4","key":"10.1016\/j.intimp.2026.116836_bb0295","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.bbrc.2018.03.226","article-title":"TREM2 modulates microglia phenotypes in the neuroinflammation of Parkinson\u2019s disease","volume":"499","author":"Zhang","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692600682X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S156757692600682X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T19:59:47Z","timestamp":1789243187000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S156757692600682X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":59,"alternative-id":["S156757692600682X"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116836","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recombinant humanized type III collagen attenuates recurrent spontaneous abortion by regulating stromal cell decidualization and reinforcing protective immune microenvironment at the maternal\u2013fetal interface","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.116836","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116836"}}