{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:06:35Z","timestamp":1789146395358,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015308","name":"Xinjiang Uygur Autonomous Region Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015308","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.intimp.2026.117265","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T15:50:20Z","timestamp":1786377020000},"page":"117265","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["miR-221-3p\u2013mediated CPT2 suppression links cardiomyocyte metabolic stress to NET-associated inflammation in myocardial ischemia\u2013reperfusion injury: Multi-omics evidence and experimental validation"],"prefix":"10.1016","volume":"187","author":[{"given":"Malike","family":"Mutailipu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abudousaimi","family":"Aini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duolikun","family":"Mutailifu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subi","family":"Maimaitirexiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maiwurulila","family":"Maiwulanjiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diliyaer","family":"Paerhati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abudunaibi","family":"Maimaitiaili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.intimp.2026.117265_bb0005","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1161\/CIR.0000000000001123","article-title":"Heart disease and stroke statistics-2023 update: a report from the American Heart Association","volume":"147","author":"Tsao","year":"2023","journal-title":"Circulation"},{"issue":"25","key":"10.1016\/j.intimp.2026.117265_bb0010","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.intimp.2026.117265_bb0015","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJMra071667","article-title":"Myocardial reperfusion injury","volume":"357","author":"Yellon","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"12","key":"10.1016\/j.intimp.2026.117265_bb0020","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/s41569-020-0403-y","article-title":"Myocardial ischaemia-reperfusion injury and cardioprotection in perspective","volume":"17","author":"Heusch","year":"2020","journal-title":"Nat. Rev. Cardiol."},{"issue":"27","key":"10.1016\/j.intimp.2026.117265_bb0025","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1093\/eurheartj\/ehac223","article-title":"Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies","volume":"43","author":"Frantz","year":"2022","journal-title":"Eur. Heart J."},{"issue":"10","key":"10.1016\/j.intimp.2026.117265_bb0030","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1161\/CIRCRESAHA.121.318241","article-title":"Cardiac energy metabolism in heart failure","volume":"128","author":"Lopaschuk","year":"2021","journal-title":"Circ. Res."},{"key":"10.1016\/j.intimp.2026.117265_bb0035","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1146\/annurev-physiol-021115-105045","article-title":"The biochemistry and physiology of mitochondrial fatty acid \u03b2-oxidation and its genetic disorders","volume":"78","author":"Houten","year":"2016","journal-title":"Annu. Rev. Physiol."},{"issue":"11","key":"10.1016\/j.intimp.2026.117265_bb0040","doi-asserted-by":"crossref","first-page":"5937","DOI":"10.1111\/jcmm.15180","article-title":"Cardiac metabolism as a driver and therapeutic target of myocardial infarction","volume":"24","author":"Zuurbier","year":"2020","journal-title":"J. Cell. Mol. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0045","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1152\/physrev.00015.2009","article-title":"Myocardial fatty acid metabolism in health and disease","volume":"90","author":"Lopaschuk","year":"2010","journal-title":"Physiol. Rev."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0050","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1161\/CIRCGENETICS.109.852814","article-title":"Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events","volume":"3","author":"Shah","year":"2010","journal-title":"Circ. Cardiovasc. Genet."},{"issue":"9","key":"10.1016\/j.intimp.2026.117265_bb0055","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1161\/CIRCRESAHA.117.311002","article-title":"Cardiovascular metabolomics","volume":"122","author":"McGarrah","year":"2018","journal-title":"Circ. Res."},{"issue":"5","key":"10.1016\/j.intimp.2026.117265_bb0060","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrcardio.2014.28","article-title":"The inflammatory response in myocardial injury, repair, and remodelling","volume":"11","author":"Frangogiannis","year":"2014","journal-title":"Nat. Rev. Cardiol."},{"issue":"5663","key":"10.1016\/j.intimp.2026.117265_bb0065","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0070","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/nri.2017.105","article-title":"Neutrophil extracellular traps in immunity and disease","volume":"18","author":"Papayannopoulos","year":"2017","journal-title":"Nat. Rev. Immunol."},{"issue":"22","key":"10.1016\/j.intimp.2026.117265_bb0075","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1093\/eurheartj\/ehv007","article-title":"Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction","volume":"36","author":"Stakos","year":"2015","journal-title":"Eur. Heart J."},{"issue":"5","key":"10.1016\/j.intimp.2026.117265_bb0080","doi-asserted-by":"crossref","first-page":"H500","DOI":"10.1152\/ajpheart.00381.2014","article-title":"Neutrophil extracellular traps in ischemia-reperfusion injury-induced myocardial no-reflow: therapeutic potential of DNase-based reperfusion strategy","volume":"308","author":"Ge","year":"2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0085","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1182\/blood-2013-07-514992","article-title":"VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia\/reperfusion injury in mice","volume":"123","author":"Savchenko","year":"2013","journal-title":"Blood"},{"issue":"7444","key":"10.1016\/j.intimp.2026.117265_bb0090","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/nature11986","article-title":"Succinate is an inflammatory signal that induces IL-1\u03b2 through HIF-1\u03b1","volume":"496","author":"Tannahill","year":"2013","journal-title":"Nature"},{"issue":"7699","key":"10.1016\/j.intimp.2026.117265_bb0095","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature25986","article-title":"Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1","volume":"556","author":"Mills","year":"2018","journal-title":"Nature"},{"issue":"7454","key":"10.1016\/j.intimp.2026.117265_bb0100","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nature12175","article-title":"Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo","volume":"498","author":"L\u00e4mmermann","year":"2013","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0105","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/s41392-024-01933-x","article-title":"Neutrophil extracellular traps in homeostasis and disease","volume":"9","author":"Wang","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"issue":"9","key":"10.1016\/j.intimp.2026.117265_bb0110","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1042\/BCJ20160164","article-title":"Long-chain acylcarnitines determine ischaemia\/reperfusion-induced damage in heart mitochondria","volume":"473","author":"Liepinsh","year":"2016","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0115","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/s41588-022-01270-1","article-title":"Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases","volume":"55","author":"Chen","year":"2023","journal-title":"Nat. Genet."},{"issue":"7944","key":"10.1016\/j.intimp.2026.117265_bb0120","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/s41586-022-05473-8","article-title":"FinnGen provides genetic insights from a well-phenotyped isolated population","volume":"613","author":"Kurki","year":"2023","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.intimp.2026.117265_bb0125","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/gepi.21758","article-title":"Mendelian randomization analysis with multiple genetic variants using summarized data","volume":"37","author":"Burgess","year":"2013","journal-title":"Genet. Epidemiol."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0130","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ije\/dyv080","article-title":"Mendelian randomization with invalid instruments: effect estimation and bias detection through egger regression","volume":"44","author":"Bowden","year":"2015","journal-title":"Int. J. Epidemiol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117265_bb0135","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/gepi.21965","article-title":"Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet. Epidemiol."},{"issue":"W1","key":"10.1016\/j.intimp.2026.117265_bb0140","doi-asserted-by":"crossref","first-page":"W398","DOI":"10.1093\/nar\/gkae253","article-title":"MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation","volume":"52","author":"Pang","year":"2024","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0145","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/s41592-024-02561-7","article-title":"SMR-portal: an online platform for integrative analysis of GWAS and xQTL data to identify complex trait genes","volume":"22","author":"Guo","year":"2025","journal-title":"Nat. Methods"},{"issue":"7","key":"10.1016\/j.intimp.2026.117265_bb0150","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.intimp.2026.117265_bb0155","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1093\/bioinformatics\/btab711","article-title":"ImmuCellAI-mouse: a tool for comprehensive prediction of mouse immune cell abundance and immune microenvironment depiction","volume":"38","author":"Miao","year":"2022","journal-title":"Bioinformatics"},{"issue":"13","key":"10.1016\/j.intimp.2026.117265_bb0160","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.intimp.2026.117265_bb0165","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat. Methods"},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0170","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/s41590-018-0276-y","article-title":"Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage","volume":"20","author":"Aran","year":"2019","journal-title":"Nat. Immunol."},{"issue":"6282","key":"10.1016\/j.intimp.2026.117265_bb0175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1126\/science.aad0501","article-title":"Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq","volume":"352","author":"Tirosh","year":"2016","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0180","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1158\/2159-8290.CD-21-0316","article-title":"Spatiotemporal immune landscape of colorectal cancer liver metastasis at single-cell level","volume":"12","author":"Wu","year":"2021","journal-title":"Cancer Discov."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0185","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using CellChat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.intimp.2026.117265_bb0190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0206239","article-title":"miRWalk: an online resource for prediction of microRNA binding sites","volume":"13","author":"Sticht","year":"2018","journal-title":"PLoS One"},{"issue":"6472","key":"10.1016\/j.intimp.2026.117265_bb0195","doi-asserted-by":"crossref","DOI":"10.1126\/science.aav1741","article-title":"The biochemical basis of microRNA targeting efficacy","volume":"366","author":"McGeary","year":"2019","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.intimp.2026.117265_bb0200","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/s41577-018-0065-8","article-title":"Cardioimmunology: the immune system in cardiac homeostasis and disease","volume":"18","author":"Swirski","year":"2018","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2026.117265_bb0205","first-page":"L342","article-title":"HMGB1 promotes neutrophil extracellular trap formation through interactions with toll-like receptor 4","volume":"304","author":"Tadie","year":"2013","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"issue":"10","key":"10.1016\/j.intimp.2026.117265_bb0210","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nrendo.2015.129","article-title":"Acylcarnitines\u2014old actors auditioning for new roles in metabolic physiology","volume":"11","author":"McCoin","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0215","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1161\/01.RES.55.2.135","article-title":"Amphipathic metabolites and membrane dysfunction in ischemic myocardium","volume":"55","author":"Corr","year":"1984","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0220","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.003620","article-title":"Serum acylcarnitines and risk of cardiovascular death and acute myocardial infarction in patients with stable angina pectoris","volume":"6","author":"Strand","year":"2017","journal-title":"J. Am. Heart Assoc."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0225","doi-asserted-by":"crossref","first-page":"5729","DOI":"10.1038\/s41467-024-50125-2","article-title":"Plasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease","volume":"15","author":"Lv","year":"2024","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.intimp.2026.117265_bb0230","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.003190","article-title":"Metabolomic profiling identifies novel circulating biomarkers of mitochondrial dysfunction differentially elevated in heart failure with preserved versus reduced ejection fraction: evidence for shared metabolic impairments in clinical heart failure","volume":"5","author":"Hunter","year":"2016","journal-title":"J. Am. Heart Assoc."},{"issue":"6","key":"10.1016\/j.intimp.2026.117265_bb0235","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1194\/jlr.M300512-JLR200","article-title":"Identification of the peroxisomal beta-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids","volume":"45","author":"Ferdinandusse","year":"2004","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.intimp.2026.117265_bb0240","doi-asserted-by":"crossref","first-page":"1371805","DOI":"10.3389\/fcvm.2024.1371805","article-title":"Circulating metabolites and coronary heart disease: a bidirectional Mendelian randomization","volume":"11","author":"Chen","year":"2024","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.intimp.2026.117265_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103184","article-title":"Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation","volume":"73","author":"Wu","year":"2024","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0250","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s41419-025-07699-6","article-title":"Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages","volume":"16","author":"Chen","year":"2025","journal-title":"Cell Death Dis."},{"issue":"11","key":"10.1016\/j.intimp.2026.117265_bb0255","article-title":"ACSL1 aggravates thromboinflammation by LPC\/LPA metabolic axis in hyperlipidemia associated myocardial ischemia-reperfusion injury","volume":"12","author":"Jiang","year":"2025","journal-title":"Adv. Sci. (Weinh)."},{"issue":"1","key":"10.1016\/j.intimp.2026.117265_bb0260","first-page":"10","article-title":"Myocardial ischemia\/reperfusion: translational pathophysiology of ischemic heart disease","volume":"5","author":"Heusch","year":"2024","journal-title":"Med (N Y)."},{"key":"10.1016\/j.intimp.2026.117265_bb0265","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.omtn.2019.05.018","article-title":"MicroRNA-221 is cardioprotective and anti-fibrotic in a rat model of myocardial infarction","volume":"17","author":"Zhou","year":"2019","journal-title":"Mol. Ther. Nucleic Acids."},{"issue":"2","key":"10.1016\/j.intimp.2026.117265_bb0270","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/HYPERTENSIONAHA.117.10094","article-title":"MicroRNA-221\/222 family counteracts myocardial fibrosis in pressure overload-induced heart failure","volume":"71","author":"Verjans","year":"2017","journal-title":"Hypertension"}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926011112?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926011112?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:11:55Z","timestamp":1789143115000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926011112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":54,"alternative-id":["S1567576926011112"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117265","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"miR-221-3p\u2013mediated CPT2 suppression links cardiomyocyte metabolic stress to NET-associated inflammation in myocardial ischemia\u2013reperfusion injury: Multi-omics evidence and experimental validation","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117265","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117265"}}