{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:01:00Z","timestamp":1790438460101,"version":"4.1.0"},"reference-count":198,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82405014"],"award-info":[{"award-number":["82405014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004001","name":"Guizhou Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["GMULH (2025) 019"],"award-info":[{"award-number":["GMULH (2025) 019"]}],"id":[{"id":"10.13039\/501100004001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.intimp.2026.117293","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T07:14:54Z","timestamp":1787210094000},"page":"117293","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Traditional Chinese medicine for neutrophil-mediated acute lung injury: from single-mechanism targeting to multi-mechanism synergistic regulation"],"prefix":"10.1016","volume":"188","author":[{"given":"Xiaohui","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0005","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s00508-021-01971-3","article-title":"Association between inflammatory biomarkers and acute respiratory distress syndrome or acute lung injury risk","volume":"134","author":"Liu","year":"2022","journal-title":"Wien. Klin. Wochenschr."},{"key":"10.1016\/j.intimp.2026.117293_bb0010","series-title":"What factors predispose patients to acute respiratory distress syndrome?: evidence-based practice of critical care","first-page":"103","author":"Odeyemi","year":"2020"},{"key":"10.1016\/j.intimp.2026.117293_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115153","article-title":"NF-\u03baB and AMPK-Nrf2 pathways support the protective effect of polysaccharides from Polygonatum cyrtonema Hua in lipopolysaccharide-induced acute lung injury","volume":"291","author":"Gan","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"21","key":"10.1016\/j.intimp.2026.117293_bb0020","article-title":"Biomarkers, signaling pathways, and programmed cell death in acute lung injury and its treatment with traditional Chinese medicine: a narrative review","volume":"27","author":"An","year":"2023","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"32","key":"10.1016\/j.intimp.2026.117293_bb0025","doi-asserted-by":"crossref","first-page":"12153","DOI":"10.1021\/acs.jafc.2c08926","article-title":"Sepsis-induced acute lung injury is alleviated by small molecules from dietary plants via pyroptosis modulation","volume":"71","author":"Wu","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.intimp.2026.117293_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.108516","article-title":"Neutrophil extracellular traps (NETs) and Covid-19: a new frontiers for therapeutic modality","volume":"104","author":"Al-Kuraishy","year":"2022","journal-title":"Int. Immunopharmacol."},{"issue":"13","key":"10.1016\/j.intimp.2026.117293_bb0035","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1093\/cvr\/cvab329","article-title":"Neutrophil extracellular traps: from physiology to pathology","volume":"118","author":"Hidalgo","year":"2022","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0040","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.941914","article-title":"Lysophosphatidylcholine alleviates acute lung injury by regulating neutrophil motility and neutrophil extracellular trap formation","volume":"10","author":"Jeong","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0045","doi-asserted-by":"crossref","first-page":"851","DOI":"10.3390\/ijms21030851","article-title":"Neutrophil adaptations upon recruitment to the lung: new concepts and implications for homeostasis and disease","volume":"21","author":"Giacalone","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.117293_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.00962","article-title":"Neutrophils in tuberculosis-associated inflammation and lung pathology","volume":"11","author":"Muefong","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.113948","article-title":"Aerosol inhalation of rhIL-10 improves acute lung injury in mice by affecting pulmonary neutrophil phenotypes through neutrophil-platelet aggregates","volume":"147","author":"Qin","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"17","key":"10.1016\/j.intimp.2026.117293_bb0060","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1182\/blood.2023019940","article-title":"A key role for platelet GPVI in neutrophil recruitment, migration, and NETosis in the early stages of acute lung injury","volume":"142","author":"Burkard","year":"2023","journal-title":"Blood"},{"key":"10.1016\/j.intimp.2026.117293_bb0065","article-title":"Dual role of IL-17A in COPD: amplifier of inflammatory cascades and mediator of airway remodeling and alveolar destruction","volume":"17","author":"Zhang","year":"2026","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0070","doi-asserted-by":"crossref","DOI":"10.3390\/antiox12030548","article-title":"Oxidative stress and inflammation in acute and chronic lung injuries","volume":"12","author":"Bezerra","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.intimp.2026.117293_bb0075","volume":"16","author":"Han","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0080","article-title":"Exploring the pathogenesis of acute lung injury and its treatment through traditional Chinese medicine: a state-of-the-art review","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120855","article-title":"Lifei Qingchang granules alleviate airway inflammation in a mouse model of bronchiectasis by inhibiting neutrophil extracellular traps","volume":"356","author":"Yuanlong","year":"2026","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0090","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13020-023-00739-3","article-title":"Liquiritin exhibits anti-acute lung injury activities through suppressing the JNK\/Nur77\/c-Jun pathway","volume":"18","author":"Zhou","year":"2023","journal-title":"Chin. Med."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0095","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/s41423-020-00581-9","article-title":"Uncovering the multifaceted roles played by neutrophils in allogeneic hematopoietic stem cell transplantation","volume":"18","author":"Tecchio","year":"2021","journal-title":"Cell. Mol. Immunol."},{"issue":"10","key":"10.1016\/j.intimp.2026.117293_bb0100","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1093\/ndt\/gfad266","article-title":"Neutrophils\u2014biology and diversity","volume":"39","author":"Maier-Begandt","year":"2024","journal-title":"Nephrol. Dial. Transplant."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0105","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/s41392-024-02049-y","article-title":"Neutrophil diversity and function in health and disease","volume":"9","author":"Zhang","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0110","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00441-017-2748-z","article-title":"Neutrophils in the lung: \u201cthe first responders\u201d","volume":"371","author":"Aulakh","year":"2018","journal-title":"Cell Tissue Res."},{"issue":"7","key":"10.1016\/j.intimp.2026.117293_bb0115","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.it.2019.04.013","article-title":"The neutrophil life cycle","volume":"40","author":"Hidalgo","year":"2019","journal-title":"Trends Immunol."},{"issue":"6","key":"10.1016\/j.intimp.2026.117293_bb0120","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24065125","article-title":"NETs promote inflammatory injury by activating cGAS-STING pathway in acute lung injury","volume":"24","author":"Zhao","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0125","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.18632\/oncotarget.22744","article-title":"Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI\/ARDS","volume":"9","author":"Li","year":"2018","journal-title":"Oncotarget"},{"issue":"8","key":"10.1016\/j.intimp.2026.117293_bb0130","doi-asserted-by":"crossref","first-page":"4107","DOI":"10.1007\/s10238-023-01180-4","article-title":"Recent advances in the role of neutrophils and neutrophil extracellular traps in acute pancreatitis","volume":"23","author":"Ishqi","year":"2023","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.intimp.2026.117293_bb0135","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.714943","article-title":"Janus kinase inhibition ameliorates ischemic stroke injury and Neuroinflammation through reducing NLRP3 Inflammasome activation via JAK2\/STAT3 pathway inhibition","volume":"12","author":"Zhu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116615","article-title":"Shiwei Qingwen decoction regulates TLR4\/NF-\u03baB signaling pathway and NLRP3 inflammasome to reduce inflammatory response in lipopolysaccharide-induced acute lung injury","volume":"313","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0145","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/s12964-024-01620-y","article-title":"Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications","volume":"22","author":"Qiao","year":"2024","journal-title":"Cell Commun. Signal"},{"issue":"9","key":"10.1016\/j.intimp.2026.117293_bb0150","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.1007\/s00018-021-03768-z","article-title":"Regulatory mechanisms of neutrophil migration from the circulation to the airspace","volume":"78","author":"Lin","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0155","article-title":"Classic signaling pathways in alveolar injury and repair involved in sepsis-induced ALI\/ARDS: new research progress and prospect","volume":"2022","author":"Li","year":"2022","journal-title":"Dis. Markers"},{"key":"10.1016\/j.intimp.2026.117293_bb0160","series-title":"In search of novel immune-modulatory compounds from british columbia wild mushrooms and their effectiveness in inflammatory micro-circulation of mice","author":"Javed","year":"2017"},{"key":"10.1016\/j.intimp.2026.117293_bb0165","article-title":"Chimonanthus salicifolius essential oil protects against endotoxin-induced acute lung injury via suppression of \u03b22 integrin-mediated neutrophil adhesion and chemotaxis","volume":"353","author":"Yijie","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0170","article-title":"Phillyrin counters \u03b22 integrin-mediated neutrophil adhesion and chemotaxis to alleviate endotoxin-induced acute lung injury in neonatal rats","volume":"237","author":"Feng","year":"2025","journal-title":"Biochem. Pharmacol."},{"issue":"173","key":"10.1016\/j.intimp.2026.117293_bb0175","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0172-2023","article-title":"A narrative review of chemokine receptors CXCR1 and CXCR2 and their role in acute respiratory distress syndrome","volume":"33","author":"Toya","year":"2024","journal-title":"Eur. Respir. Rev."},{"issue":"6","key":"10.1016\/j.intimp.2026.117293_bb0180","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1159\/000430914","article-title":"Chemokine CXCL1-mediated neutrophil trafficking in the lung: role of CXCR2 activation","volume":"7","author":"Sawant","year":"2015","journal-title":"J. Innate Immun."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0185","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s12964-022-00994-1","article-title":"Salidroside attenuates HALI via IL-17A-mediated ferroptosis of alveolar epithelial cells by regulating Act1-TRAF6-p38 MAPK pathway","volume":"20","author":"Guo","year":"2022","journal-title":"Cell Commun. Signal"},{"key":"10.1016\/j.intimp.2026.117293_bb0190","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01293","article-title":"TRAF regulation of IL-17 cytokine signaling","volume":"10","author":"Swaidani","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0195","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.689866","article-title":"Neutrophil-dependent immunity during pulmonary infections and inflammations","volume":"12","author":"Effah","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.121310","article-title":"BAP31 regulates the expression of ICAM-1\/VCAM-1 via MyD88\/NF-\u03baB pathway in acute lung injury mice model","volume":"313","author":"Li","year":"2023","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0205","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4314\/ahs.v23i1.5","article-title":"An evaluation of matrix metalloproteinase-9 (Mmp-9) and tissue inhibitor metalloproteinase-1 (Timp-1) serum levels and the Mmp-9\/Timp-1 ratio in Covid-19 patients","volume":"23","author":"Demir","year":"2023","journal-title":"Afr. Health Sci."},{"key":"10.1016\/j.intimp.2026.117293_bb0210","article-title":"A traditional herbal formula, Deng-Shi-Qing-Mai-Tang, regulates TLR4\/NF-\u03baB signaling pathway to reduce inflammatory response in PM2.5-induced lung injury","volume":"91","author":"Zhou","year":"2021","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.intimp.2026.117293_bb0215","article-title":"Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4\/MyD88\/NF-\u03baB pathway","volume":"301","author":"Yanhui","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0220","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2025.13741","article-title":"Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: insights and therapeutic perspectives (review)","volume":"33","author":"Zhang","year":"2026","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0225","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s12931-022-02065-y","article-title":"Delayed neutrophil apoptosis may enhance NET formation in ARDS","volume":"23","author":"Song","year":"2022","journal-title":"Respir. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0230","series-title":"Molecular and Functional Insights into the Pulmonary Vasculature","first-page":"41","article-title":"The pulmonary vascular barrier: Insights into structure, function, and regulatory mechanisms","author":"Parthasarathi","year":"2018"},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0235","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.7150\/ijbs.66477","article-title":"Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury","volume":"18","author":"Qin","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"5","key":"10.1016\/j.intimp.2026.117293_bb0240","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1007\/s00210-023-02813-x","article-title":"Bakuchiol regulates TLR4\/MyD88\/NF-\u03baB and Keap1\/Nrf2\/HO-1 pathways to protect against LPS-induced acute lung injury in vitro and in vivo","volume":"397","author":"Zhao","year":"2024","journal-title":"Naunyn Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0245","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1628481","article-title":"The cGAS-STING signaling pathway in the regulation of pulmonary infections: a systematic review","volume":"15","author":"Xu","year":"2025","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0250","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00011-023-01844-7","article-title":"Advances in lung ischemia\/reperfusion injury: unraveling the role of innate immunity","volume":"73","author":"Li","year":"2024","journal-title":"Inflamm. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0255","doi-asserted-by":"crossref","first-page":"968","DOI":"10.4049\/jimmunol.2100593","article-title":"HMGB1-mediated neutrophil extracellular trap formation exacerbates intestinal ischemia\/reperfusion-induced acute lung injury","volume":"208","author":"Zhan","year":"2022","journal-title":"J. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0260","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1559659","article-title":"Cell death in acute lung injury: caspase-regulated apoptosis, pyroptosis, necroptosis, and PANoptosis","volume":"16","author":"Xiao","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0265","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.2147\/JIR.S309457","article-title":"Capsaicin protects against lipopolysaccharide-induced acute lung injury through the HMGB1\/NF-\u03baB and PI3K\/AKT\/mTOR pathways","volume":"14","author":"Chen","year":"2021","journal-title":"J. Inflamm. Res."},{"issue":"5","key":"10.1016\/j.intimp.2026.117293_bb0270","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2025.13665","article-title":"The role of Na,K-ATPase in lung diseases (review)","volume":"32","author":"Liu","year":"2025","journal-title":"Mol. Med. Rep."},{"issue":"0","key":"10.1016\/j.intimp.2026.117293_bb0275","doi-asserted-by":"crossref","first-page":"12825","DOI":"10.2147\/JIR.S535701","article-title":"The crucial roles of platelets as immune mediators in Sepsis","volume":"18","author":"Yang","year":"2025","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0280","series-title":"Pulmonary vasculature redox signaling in health and disease","first-page":"105","article-title":"ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)","author":"Kellner","year":"2017"},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0285","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3390\/genes10030183","article-title":"Progression of cystic fibrosis lung disease from childhood to adulthood: neutrophils, neutrophil extracellular trap (NET) formation, and NET degradation","volume":"10","author":"Khan","year":"2019","journal-title":"Genes"},{"key":"10.1016\/j.intimp.2026.117293_bb0290","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01472","article-title":"Nox2 regulates platelet activation and NET formation in the lung","volume":"10","author":"Hook","year":"2019","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0295","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/imm.12981","article-title":"Low-molecular-mass hyaluronan induces pulmonary inflammation by up-regulation of Mcl-1 to inhibit neutrophil apoptosis via PI3K\/Akt1 pathway","volume":"155","author":"Zhao","year":"2018","journal-title":"Immunology"},{"key":"10.1016\/j.intimp.2026.117293_bb0300","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.1059686","article-title":"Early mechanisms of neutrophil activation and transmigration in acute lung injury","volume":"13","author":"Cagle","year":"2022","journal-title":"Front. Physiol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0305","doi-asserted-by":"crossref","first-page":"859","DOI":"10.4049\/jimmunol.1600618","article-title":"Pulmonary epithelial TLR4 activation leads to lung injury in neonatal necrotizing enterocolitis","volume":"197","author":"Jia","year":"2016","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.intimp.2026.117293_bb0310","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000492950","article-title":"The pathogenic involvement of neutrophils in acute respiratory distress syndrome and transfusion-related acute lung injury","volume":"45","author":"Rebetz","year":"2018","journal-title":"Transfus. Med. Hemother."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0315","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.2147\/JIR.S348850","article-title":"Apelin-13 attenuates lipopolysaccharide-induced inflammatory responses and acute lung injury by regulating PFKFB3-driven glycolysis induced by NOX4-dependent ROS","volume":"15","author":"Yuan","year":"2022","journal-title":"J. Inflamm. Res."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0320","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41421-020-0167-x","article-title":"Inflammasome activation and regulation: toward a better understanding of complex mechanisms","volume":"6","author":"Zheng","year":"2020","journal-title":"Cell Discov."},{"key":"10.1016\/j.intimp.2026.117293_bb0325","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2019.01332","article-title":"Liang-Ge-san, a classic traditional Chinese medicine formula, attenuates lipopolysaccharide-induced acute lung injury through up-regulating miR-21","volume":"10","author":"Yang","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0330","article-title":"Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway","volume":"16","author":"Zhou","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"6","key":"10.1016\/j.intimp.2026.117293_bb0335","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.3390\/ijms24065125","article-title":"NETs promote inflammatory injury by activating cGAS-STING pathway in acute lung injury","volume":"24","author":"Zhao","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0340","doi-asserted-by":"crossref","first-page":"13291","DOI":"10.2147\/JIR.S543273","article-title":"Crosstalk between cell death and the cGAS-STING pathway in sepsis-associated acute lung injury","volume":"18","author":"Li","year":"2025","journal-title":"J. Inflamm. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0345","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s10753-021-01439-6","article-title":"The signaling pathways regulating NLRP3 inflammasome activation","volume":"44","author":"Chen","year":"2021","journal-title":"Inflammation"},{"issue":"9","key":"10.1016\/j.intimp.2026.117293_bb0350","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0161975","article-title":"Src family kinases modulate the loss of endothelial barrier function in response to TNF-\u03b1: crosstalk with p38 signaling","volume":"11","author":"Adam","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.intimp.2026.117293_bb0355","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.freeradbiomed.2019.09.021","article-title":"Resveratrol suppresses neutrophil activation via inhibition of Src family kinases to attenuate lung injury","volume":"145","author":"Tsai","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2026.117293_bb0360","article-title":"Jinzhen oral liquid alleviates lipopolysaccharide-induced acute lung injury through modulating TLR4\/MyD88\/NF-\u03baB pathway","volume":"114","author":"Li","year":"2023","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.intimp.2026.117293_bb0365","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2019.105842","article-title":"Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K\/AKT pathway in acute lung injury","volume":"76","author":"Luo","year":"2019","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0370","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s11658-023-00495-0","article-title":"Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury","volume":"28","author":"Ling","year":"2023","journal-title":"Cell. Mol. Biol. Lett."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0375","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1007\/s12013-024-01651-9","article-title":"IRF7 activates LCN2 transcription to enhance LPS-induced acute lung injury by inducing macrophage ferroptosis and M1 polarization","volume":"83","author":"Lv","year":"2025","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.intimp.2026.117293_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120419","article-title":"Chimonanthus salicifolius essential oil protects against endotoxin-induced acute lung injury via suppression of \u03b22 integrin-mediated neutrophil adhesion and chemotaxis","volume":"353","author":"Chen","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0385","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.660760","article-title":"\u03b22 integrin regulation of neutrophil functional plasticity and fate in the resolution of inflammation","volume":"12","author":"Sekheri","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0390","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.02491","article-title":"Misunderstandings between platelets and neutrophils build in chronic inflammation","volume":"10","author":"Ramirez","year":"2019","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0395","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3892\/br.2022.1500","article-title":"Advances in research on the effects of platelet activation in acute lung injury (review)","volume":"16","author":"Xin","year":"2022","journal-title":"Biomed Rep."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0400","doi-asserted-by":"crossref","DOI":"10.1007\/s10571-026-01675-0","article-title":"The interaction of neutrophil extracellular traps and complement in intracerebral hemorrhage","volume":"46","author":"Shang","year":"2026","journal-title":"Cell. Mol. Neurobiol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0405","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.chest.2019.06.012","article-title":"The emerging role of neutrophil extracellular traps in respiratory disease","volume":"156","author":"Twaddell","year":"2019","journal-title":"Chest"},{"issue":"8","key":"10.1016\/j.intimp.2026.117293_bb0410","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.7150\/ijbs.69141","article-title":"Neutrophil extracellular traps mediate m(6)A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells","volume":"18","author":"Zhang","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"03","key":"10.1016\/j.intimp.2026.117293_bb0415","first-page":"e93","article-title":"Mechanisms and research progress of traditional Chinese medicine regulating NF-\u03baB in the treatment of acute lung injury\/acute respiratory distress syndrome","volume":"04","author":"Zuo","year":"2024","journal-title":"Chin. Med. Nat. Prod."},{"key":"10.1016\/j.intimp.2026.117293_bb0420","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2026.1796360","article-title":"Bimodal regulation and precision therapy of neutrophil extracellular traps in liver ischemia-reperfusion injury: recent advances","volume":"17","author":"An","year":"2026","journal-title":"Front. Immunol."},{"issue":"7","key":"10.1016\/j.intimp.2026.117293_bb0425","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1111\/jth.15313","article-title":"PAD4 takes charge during neutrophil activation: impact of PAD4 mediated NET formation on immune-mediated disease","volume":"19","author":"Liu","year":"2021","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.intimp.2026.117293_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2020.109906","article-title":"Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: targeting a potential IL-1\u03b2\/neutrophil extracellular traps feedback loop","volume":"143","author":"Yaqinuddin","year":"2020","journal-title":"Med. Hypotheses"},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0435","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.3390\/ijms25031464","article-title":"A narrative review: the role of NETs in acute respiratory distress syndrome\/acute lung injury","volume":"25","author":"Zhou","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0440","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.98178","article-title":"Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury","volume":"3","author":"Lefran\u00e7ais","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.intimp.2026.117293_bb0445","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.953195","article-title":"The role of neutrophil extracellular traps in acute lung injury","volume":"13","author":"Scozzi","year":"2022","journal-title":"Front. Immunol."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0450","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.2147\/JIR.S321513","article-title":"Neutrophil extracellular traps augmented alveolar macrophage pyroptosis via AIM2 inflammasome activation in LPS-induced ALI\/ARDS","volume":"14","author":"Li","year":"2021","journal-title":"J. Inflamm. Res."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0455","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.3892\/etm.2021.10508","article-title":"Protectin D1 protects against lipopolysaccharide-induced acute lung injury through inhibition of neutrophil infiltration and the formation of neutrophil extracellular traps in lung tissue","volume":"22","author":"Wu","year":"2021","journal-title":"Exp. Ther. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0460","article-title":"Immunomodulatory effect of Chinese herbal medicine formula Sheng-Fei-Yu-Chuan-Tang in lipopolysaccharide-induced acute lung injury mice","volume":"2013","author":"Lin","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0465","article-title":"Suppressive effects of GSS on lipopolysaccharide-induced endothelial cell injury and ALI via TNF-\u03b1 and IL-6","volume":"2019","author":"Yi","year":"2019","journal-title":"Mediat. Inflamm."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0470","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3109\/08820139.2016.1157814","article-title":"Dexamethasone attenuates LPS-induced acute lung injury through inhibition of NF-\u03baB, COX-2, and pro-inflammatory mediators","volume":"45","author":"Al-Harbi","year":"2016","journal-title":"Immunol. Investig."},{"issue":"5","key":"10.1016\/j.intimp.2026.117293_bb0475","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/path.5221","article-title":"Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential","volume":"247","author":"Potey","year":"2019","journal-title":"J. Pathol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0480","first-page":"7527953","article-title":"Neutrophil extracellular traps (NETs) and damage-associated molecular patterns (DAMPs): two potential targets for COVID-19 treatment","volume":"2020","author":"Cicco","year":"2020","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0485","article-title":"Salvianolic acid a protects against lipopolysaccharide-induced acute lung injury by inhibiting neutrophil NETosis","volume":"2022","author":"Liu","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0490","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12931-015-0275-6","article-title":"Activation of Src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury","volume":"16","author":"Li","year":"2015","journal-title":"Respir. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0495","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2017.00373","article-title":"Neutrophils to the ROScue: mechanisms of NADPH oxidase activation and bacterial resistance","volume":"7","author":"Nguyen","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"6","key":"10.1016\/j.intimp.2026.117293_bb0500","doi-asserted-by":"crossref","first-page":"890","DOI":"10.3390\/antiox10060890","article-title":"NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology","volume":"10","author":"Vermot","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.intimp.2026.117293_bb0505","series-title":"An Inhaled neutrophil elastase inhibitor alleviates lipopolysaccharide-mediated neutrophil extracellular trap formation in acute lung injury via the MAPK\/AKT\/NLRP3 pathway","author":"Aji","year":"2024"},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0510","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3390\/antiox13010132","article-title":"The roles of neutrophil-derived myeloperoxidase (MPO) in diseases: the new Progress","volume":"13","author":"Lin","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.intimp.2026.117293_bb0515","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.00409","article-title":"Aerobic exercise attenuates acute lung injury through NET inhibition","volume":"11","author":"Shi","year":"2020","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0520","doi-asserted-by":"crossref","DOI":"10.3390\/cells8040356","article-title":"Activation of Nrf2\/HO-1 pathway and human atherosclerotic plaque vulnerability: an in vitro and in vivo study","volume":"8","author":"Fiorelli","year":"2019","journal-title":"Cells"},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0525","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines14030729","article-title":"Cumambrin B alleviates sepsis-associated acute lung injury by activating the Nrf2\/HO-1 pathway","volume":"14","author":"Que","year":"2026","journal-title":"Biomedicines"},{"key":"10.1016\/j.intimp.2026.117293_bb0530","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.1039022","article-title":"The protective effect of natural medicines against excessive inflammation and oxidative stress in acute lung injury by regulating the Nrf2 signaling pathway","volume":"13","author":"Luan","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"7","key":"10.1016\/j.intimp.2026.117293_bb0535","doi-asserted-by":"crossref","DOI":"10.3390\/molecules31071153","article-title":"Research progress on the immunomodulatory effects by dang Gui (Radix Angelica sinensis) and its active chemical components","volume":"31","author":"Li","year":"2026","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0540","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00068-019-01121-5","article-title":"Contributing factors in the development of acute lung injury in a murine double hit model","volume":"46","author":"St\u00f6rmann","year":"2020","journal-title":"Eur. J. Trauma Emerg. Surg."},{"issue":"0","key":"10.1016\/j.intimp.2026.117293_bb0545","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.2147\/IJN.S449181","article-title":"Neutrophil extracellular traps in tumors and potential use of traditional herbal medicine formulations for its regulation","volume":"19","author":"Li","year":"2024","journal-title":"Int. J. Nanomedicine"},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0550","doi-asserted-by":"crossref","first-page":"926","DOI":"10.3390\/nu12040926","article-title":"Herbal combinational medication of Glycyrrhiza glabra, Agastache rugosa containing glycyrrhizic acid, tilianin inhibits neutrophilic lung inflammation by affecting CXCL2, interleukin-17\/STAT3 signal pathways in a murine model of COPD","volume":"12","author":"Kim","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.intimp.2026.117293_bb0555","article-title":"Erianin alleviates LPS-induced acute lung injury via antagonizing P-selectin-mediated neutrophil adhesion function","volume":"331","author":"Jiangwei","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0560","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118336","article-title":"Erianin alleviates LPS-induced acute lung injury via antagonizing P-selectin-mediated neutrophil adhesion function","volume":"331","author":"Ni","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0565","doi-asserted-by":"crossref","first-page":"62","DOI":"10.3892\/ijmm.2021.4895","article-title":"Ginkgolide C attenuates lipopolysaccharide-induced acute lung injury by inhibiting inflammation via regulating the CD40\/NF-\u03baB signaling pathway","volume":"47","author":"Zhang","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.intimp.2026.117293_bb0570","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110177","article-title":"Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration","volume":"119","author":"Ni","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0575","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106338","article-title":"Robustaflavone-4\u2032-dimethyl ether from Selaginella uncinata attenuated lipopolysaccharide-induced acute lung injury via inhibiting FLT3-mediated neutrophil activation","volume":"82","author":"Wu","year":"2020","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0580","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.biopha.2016.09.020","article-title":"Resveratrol ameliorates LPS-induced acute lung injury via NLRP3 inflammasome modulation","volume":"84","author":"Lei","year":"2016","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0585","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12931-018-0756-5","article-title":"Regulation of alveolar macrophage death in acute lung inflammation","volume":"19","author":"Fan","year":"2018","journal-title":"Respir. Res."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0590","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3892\/mmr.2020.11772","article-title":"Shikonin ameliorates lipoteichoic acid-induced acute lung injury via promotion of neutrophil apoptosis","volume":"23","author":"Zhang","year":"2021","journal-title":"Mol. Med. Rep."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0595","doi-asserted-by":"crossref","first-page":"5161","DOI":"10.2147\/JIR.S446345","article-title":"Breviscapine reduces sepsis-induced acute lung injury by targeting CASP8 to regulate neutrophil apoptosis and inflammation","volume":"17","author":"Song","year":"2024","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0600","article-title":"Beneficial effects of aloperine on inflammation and oxidative stress by suppressing necroptosis in lipopolysaccharide-induced acute lung injury mouse model","volume":"100","author":"Cui","year":"2022","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.intimp.2026.117293_bb0605","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122648","article-title":"Icariside II alleviates lipopolysaccharide-induced acute lung injury by inhibiting lung epithelial inflammatory and immune responses mediated by neutrophil extracellular traps","volume":"346","author":"Li","year":"2024","journal-title":"Life Sci."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0610","doi-asserted-by":"crossref","DOI":"10.1002\/pul2.12295","article-title":"Lianhua Qingke ameliorates lipopolysaccharide-induced lung injury by inhibiting neutrophil extracellular traps formation and pyroptosis","volume":"13","author":"Peng","year":"2023","journal-title":"Pulm. Circ."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0615","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12967-021-02745-1","article-title":"Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2\/HO-1 pathway","volume":"19","author":"Li","year":"2021","journal-title":"J. Transl. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0620","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13020-024-00918-w","article-title":"Recent advances in the potential effects of natural products from traditional Chinese medicine against respiratory diseases targeting ferroptosis","volume":"19","author":"Chen","year":"2024","journal-title":"Chin. Med."},{"issue":"21","key":"10.1016\/j.intimp.2026.117293_bb0625","doi-asserted-by":"crossref","first-page":"15805","DOI":"10.3390\/ijms242115805","article-title":"Role of neutrophil extracellular traps in health and disease pathophysiology: recent insights and advances","volume":"24","author":"Islam","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.117293_bb0630","first-page":"1828","article-title":"High-mobility group box 1 (HMGB1) and autophagy in acute lung injury (ALI): a review","volume":"25","author":"Qu","year":"2019","journal-title":"Med. Sci. Monit. Int. Med. J. Exp. Clinical Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0635","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.jep.2016.09.036","article-title":"Liujunzi Tang, a famous traditional Chinese medicine, ameliorates cigarette smoke-induced mouse model of COPD","volume":"193","author":"Zhou","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118791","article-title":"Bailixiang tea, an herbal medicine formula, co-suppresses TLR2\/MAPK8 and TLR2\/NF-\u03baB signaling pathways to protect against LPS-triggered cytokine storm in mice","volume":"337","author":"Zhang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120908","article-title":"Study on the mechanism of sangbaipi decoction in treating acute lung injury via the inflammasome NLRP3 signaling pathway","volume":"357","author":"Xu","year":"2026","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0650","article-title":"An anticomplement homogeneous polysaccharide from Hedyotis diffusa attenuates lipopolysaccharide-induced acute lung injury and inhibits neutrophil extracellular trap formation","volume":"107","author":"Zhang","year":"2022","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.intimp.2026.117293_bb0655","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.intimp.2016.06.032","article-title":"Eupatorium lindleyanum DC. flavonoids fraction attenuates lipopolysaccharide-induced acute lung injury in mice","volume":"39","author":"Chu","year":"2016","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0660","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jep.2016.03.022","article-title":"Eupatorium lindleyanum DC. sesquiterpenes fraction attenuates lipopolysaccharide-induced acute lung injury in mice","volume":"185","author":"Chu","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0665","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s10753-016-0478-0","article-title":"Polysaccharides from Arnebia euchroma ameliorated endotoxic fever and acute lung injury in rats through inhibiting complement system","volume":"40","author":"Ou","year":"2017","journal-title":"Inflammation"},{"key":"10.1016\/j.intimp.2026.117293_bb0670","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1718092","article-title":"Neutrophils as key drivers of pulmonary fibrosis: unveiling mechanisms and therapeutic implications","volume":"16","author":"Liang","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0675","article-title":"Re-Du-Ning injection ameliorates LPS-induced lung injury through inhibiting neutrophil extracellular traps formation","volume":"90","author":"Yang","year":"2021","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0680","doi-asserted-by":"crossref","first-page":"46","DOI":"10.15586\/aei.v51i4.879","article-title":"Rosavin inhibits neutrophil extracellular traps formation to ameliorate sepsis-induced lung injury by regulating the MAPK pathway","volume":"51","author":"Gao","year":"2023","journal-title":"Allergol. Immunopathol."},{"key":"10.1016\/j.intimp.2026.117293_bb0685","article-title":"Qingke Pingchuan granules alleviate airway inflammation in COPD exacerbation by inhibiting neutrophil extracellular traps in mice","volume":"136","author":"Cheng","year":"2025","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0690","doi-asserted-by":"crossref","DOI":"10.1007\/s00011-026-02239-0","article-title":"Alveolar macrophage\u2013neutrophil crosstalk in acute lung injury: mechanisms, feedback loops, and therapeutic opportunities","volume":"75","author":"Tao","year":"2026","journal-title":"Inflamm. Res."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0695","first-page":"2955","article-title":"Tanshinone IIA attenuates paraquat-induced acute lung injury by modulating angiotensin-converting enzyme 2\/angiotensin-(1-7) in rats","volume":"18","author":"Wang","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.intimp.2026.117293_bb0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108971","article-title":"Sini decoction ameliorates sepsis-induced acute lung injury via regulating ACE2-Ang (1-7)-mas axis and inhibiting the MAPK signaling pathway","volume":"115","author":"Chen","year":"2019","journal-title":"Biomed. Pharmacother."},{"issue":"8","key":"10.1016\/j.intimp.2026.117293_bb0705","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1808","article-title":"Potential pharmaceuticals targeting neuroimmune interactions in treating acute lung injury","volume":"14","author":"Wu","year":"2024","journal-title":"Clin. Transl. Med."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0710","first-page":"1369","article-title":"Fennel main constituent, trans-anethole treatment against LPS-induced acute lung injury by regulation of Th17\/Treg function","volume":"18","author":"Zhang","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.intimp.2026.117293_bb0715","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.01215","article-title":"Alleviation of lipopolysaccharide-induced acute respiratory distress syndrome in rats by Yiqi Huayu Jiedu decoction: a tandem mass tag-based proteomics study","volume":"11","author":"Luo","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0720","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1269581","article-title":"From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration","volume":"14","author":"Afzal","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"24","key":"10.1016\/j.intimp.2026.117293_bb0725","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232416134","article-title":"Protective effects of Atractylodis lancea Rhizoma on lipopolysaccharide-induced acute lung injury via TLR4\/NF-\u03baB and Keap1\/Nrf2 signaling pathways in vitro and in vivo","volume":"23","author":"Shi","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0730","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s10735-025-10686-y","article-title":"Voacangine mitigates lipopolysaccharide-produced sepsis-triggered acute lung injury via inhibition of PERK\/PI3K and TLR4\/NF-\u043aB\/IL-1\u03b2 pathways in mice","volume":"57","author":"Hong","year":"2025","journal-title":"J. Mol. Histol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0735","doi-asserted-by":"crossref","first-page":"201","DOI":"10.21010\/ajtcam.v14i4.23","article-title":"Antioxidant and anti-inflammatory effects of Rhamnazin on lipopolysaccharide-induced acute lung injury and inflammation in rats","volume":"14","author":"Wu","year":"2017","journal-title":"Afr. J. Tradit. Complement. Altern. Med."},{"issue":"4","key":"10.1016\/j.intimp.2026.117293_bb0740","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1002\/ptr.7403","article-title":"The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders","volume":"36","author":"Wu","year":"2022","journal-title":"Phytother. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0745","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1285550","article-title":"Qinhuo Shanggan oral solution resolves acute lung injury by down-regulating TLR4\/NF-\u03baB signaling cascade and inhibiting NLRP3 inflammasome activation","volume":"14","author":"Tang","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0750","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jep.2016.03.057","article-title":"Kegan Liyan oral liquid ameliorates lipopolysaccharide-induced acute lung injury through inhibition of TLR4-mediated NF-\u03baB signaling pathway and MMP-9 expression","volume":"186","author":"Zhang","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0755","doi-asserted-by":"crossref","DOI":"10.48130\/targetome-0026-0006","article-title":"Multi-omics integration identifies MT2A as a biomarker and a candidate host target linking zinc dysregulation to COVID-19 mortality","volume":"2","author":"Li","year":"2026","journal-title":"Targetome"},{"key":"10.1016\/j.intimp.2026.117293_bb0760","article-title":"Xuebijing injection alleviates sepsis-induced acute lung injury by triggering ferroptosis of CCR2hi monocytes","volume":"150","author":"Yang","year":"2026","journal-title":"Phytomed. Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.intimp.2026.117293_bb0765","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118732","article-title":"XueBiJing injection improves the symptoms of sepsis-induced acute lung injury by mitigating oxidative stress and ferroptosis","volume":"337","author":"Zou","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0770","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/JS9.0000000000000789","article-title":"Neutrophil membrane-engineered Panax ginseng root-derived exosomes loaded miRNA 182-5p targets NOX4\/Drp-1\/NLRP3 signal pathway to alleviate acute lung injury in sepsis: experimental studies","volume":"110","author":"Li","year":"2024","journal-title":"Int. J. Surg."},{"key":"10.1016\/j.intimp.2026.117293_bb0775","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtcme.2026.04.001","article-title":"Qingwen Baidu decoction attenuates acute lung injury via macrophage exosomal miR-146a suppression of alveolar epithelial cell pyroptosis","author":"Yi","year":"2026","journal-title":"J. Tradit. Complement. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0780","article-title":"The role of macrophages in the pathogenesis of ALI\/ARDS","volume":"2018","author":"Huang","year":"2018","journal-title":"Mediat. Inflamm."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0785","article-title":"The role of histone modifications in acute lung injury: molecular mechanisms and potential of traditional Chinese medicine treatment","volume":"19","author":"Yan","year":"2026","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0790","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1567522","article-title":"Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiting NETosis","volume":"16","author":"Lei","year":"2025","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.intimp.2026.117293_bb0795","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.1039\/D2FO02707K","article-title":"Hesperetin attenuates sepsis-induced intestinal barrier injury by regulating neutrophil extracellular trap formation via the ROS\/autophagy signaling pathway","volume":"14","author":"Chen","year":"2023","journal-title":"Food Funct."},{"key":"10.1016\/j.intimp.2026.117293_bb0800","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.bcp.2018.06.003","article-title":"Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity","volume":"154","author":"Yang","year":"2018","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0805","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114530","article-title":"Xuanfei Baidu decoction regulates NETs formation via CXCL2\/CXCR2 signaling pathway that is involved in acute lung injury","volume":"161","author":"Zhou","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.intimp.2026.117293_bb0810","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106083","article-title":"Xuanfei Baidu decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1\/IL17A pathway","volume":"176","author":"Wang","year":"2022","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0815","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110082","article-title":"Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation","volume":"118","author":"Yang","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0820","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/FJC.0000000000000692","article-title":"Curdione ameliorated doxorubicin-induced cardiotoxicity through suppressing oxidative stress and activating Nrf2\/HO-1 pathway","volume":"74","author":"Wu","year":"2019","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0825","article-title":"Network pharmacology and experimental validation to explore the mechanism of Qing-Jin-Hua-Tan-decoction against acute lung injury","volume":"13","author":"Xiao","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0830","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/st9.0000000000000006","article-title":"Qingjin Huatan decoction attenuates lipopolysaccharide-induced acute lung injury in mice by controlling platelet-associated formation of neutrophil extracellular traps","volume":"1","author":"Xiao","year":"2023","journal-title":"Sci. Tradit. Chin.Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0835","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1186\/s12967-025-06879-4","article-title":"Trained immunity attenuated acute lung injury by activating alveolar macrophages via AKT2-PDK1 axis-mediated metabolic reprogramming","volume":"23","author":"Sun","year":"2025","journal-title":"J. Transl. Med."},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0840","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s41664-023-00248-0","article-title":"Metabolomics combined with network pharmacology uncovers effective targets of Tao-Hong-Si-Wu decoction for its protection from Sepsis-associated acute lung injury","volume":"7","author":"He","year":"2023","journal-title":"J. Anal. Test."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0845","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s11418-014-0865-5","article-title":"Chinese herbal medicine formula Tao Hong Si Wu decoction protects against cerebral ischemia\u2013reperfusion injury via PI3K\/Akt and the Nrf2 signaling pathway","volume":"69","author":"Li","year":"2015","journal-title":"J. Nat. Med."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0850","first-page":"L389","article-title":"Shear stress-induced restoration of pulmonary microvascular endothelial barrier function following ischemia reperfusion injury requires VEGFR2 signaling","volume":"328","author":"Walsh","year":"2025","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"key":"10.1016\/j.intimp.2026.117293_bb0855","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118162","article-title":"Exocarpium Citri Grandis ameliorates LPS-induced acute lung injury by suppressing inflammation, NLRP3 inflammasome, and ferroptosis","volume":"329","author":"Xu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"10","key":"10.1016\/j.intimp.2026.117293_bb0860","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.71012","article-title":"Exocarpium Citri Grandis attenuates lipopolysaccharide-induced acute liver injury through suppression of inflammatory, apoptotic, oxidative, and ferroptotic pathways","volume":"13","author":"Zhang","year":"2025","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.intimp.2026.117293_bb0865","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1688207","article-title":"Neutrophil and neutrophil extracellular traps in acute kidney injury: from mechanisms to treatments","volume":"16","author":"Fu","year":"2025","journal-title":"Front. Immunol."},{"issue":"20","key":"10.1016\/j.intimp.2026.117293_bb0870","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1111\/bph.15597","article-title":"Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity","volume":"178","author":"Kao","year":"2021","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0875","doi-asserted-by":"crossref","DOI":"10.1186\/s12950-023-00372-9","article-title":"Lonicera japonica Thunb extract ameliorates lipopolysaccharide-induced acute lung injury associated with luteolin-mediated suppression of NF-\u03baB signaling pathway","volume":"20","author":"Jia","year":"2023","journal-title":"J. Inflamm."},{"key":"10.1016\/j.intimp.2026.117293_bb0880","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2025.106764","article-title":"Lonicera japonica Thunb. In acute lung injury: a systematic review of bioactive components and multi-target mechanisms","volume":"185","author":"Cao","year":"2025","journal-title":"Fitoterapia"},{"issue":"9","key":"10.1016\/j.intimp.2026.117293_bb0885","article-title":"Lonicerae Japonicae Flos attenuates neutrophilic inflammation by inhibiting oxidative stress","volume":"11","author":"Lai","year":"2022","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"10.1016\/j.intimp.2026.117293_bb0890","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113379","article-title":"Thalictrum minus L. ameliorates particulate matter-induced acute lung injury in mice","volume":"264","author":"Badamjav","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"null","key":"10.1016\/j.intimp.2026.117293_bb0895","doi-asserted-by":"crossref","first-page":"6743","DOI":"10.2147\/IJN.S428924","article-title":"Emodin ameliorates severe acute pancreatitis-associated acute lung injury in rats by modulating exosome-specific miRNA expression profiles","volume":"18","author":"Yang","year":"2023","journal-title":"Int. J. Nanomedicine"},{"issue":"2","key":"10.1016\/j.intimp.2026.117293_bb0900","doi-asserted-by":"crossref","first-page":"857","DOI":"10.3892\/etm.2021.10289","article-title":"Emodin ameliorates acute pancreatitis-induced lung injury by suppressing NLRP3 inflammasome-mediated neutrophil recruitment","volume":"22","author":"Jiang","year":"2021","journal-title":"Exp. Ther. Med."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0905","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41392-025-02127-9","article-title":"Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies","volume":"10","author":"Ma","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"issue":"5","key":"10.1016\/j.intimp.2026.117293_bb0910","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70184","article-title":"Neutrophils in tissue injury and repair: molecular mechanisms and therapeutic targets","volume":"6","author":"Yang","year":"2025","journal-title":"MedComm"},{"key":"10.1016\/j.intimp.2026.117293_bb0915","series-title":"Exploring the Heterogeneity of Immune Response to Viral and Bacterial Infection","author":"Andres-Terre","year":"2018"},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0920","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/s13020-025-01277-w","article-title":"Technical guidelines for non-clinical pharmacological research of traditional Chinese medicine (TCM) formulae","volume":"20","author":"Li","year":"2025","journal-title":"Chin. Med."},{"issue":"27","key":"10.1016\/j.intimp.2026.117293_bb0925","first-page":"3418","article-title":"Analysis and reflection on the outcome indicators in clinical trials of traditional Chinese medicine for sepsis-induced acute lung injury\/acute respiratory distress syndrome","volume":"27","author":"Xie","year":"2024","journal-title":"Chin. Gen. Pract."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0930","doi-asserted-by":"crossref","DOI":"10.3390\/ph19010183","article-title":"Neutrophil extracellular traps: potential therapeutic targets of traditional Chinese medicine and natural products for cardiovascular diseases","volume":"19","author":"Liu","year":"2026","journal-title":"Pharmaceuticals (Basel)"},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0935","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/01902148.2024.2428939","article-title":"Animal models of infection-induced acute lung injury","volume":"50","author":"Tan","year":"2024","journal-title":"Exp. Lung Res."},{"issue":"1","key":"10.1016\/j.intimp.2026.117293_bb0940","doi-asserted-by":"crossref","DOI":"10.1186\/s13020-025-01261-4","article-title":"The role and therapeutic advances of neutrophils in acute myocardial infarction: from traditional Chinese medicine modulation to modern therapeutic strategies","volume":"20","author":"Wan","year":"2025","journal-title":"Chin. Med."},{"key":"10.1016\/j.intimp.2026.117293_bb0945","doi-asserted-by":"crossref","DOI":"10.3389\/falgy.2025.1691886","article-title":"Impact of biologic therapy on blood cell indices and exacerbation risk in severe asthma: predictive value of the neutrophil-to-eosinophil ratio","volume":"6","author":"Al-Ahmad","year":"2025","journal-title":"Front. Allergy"},{"key":"10.1016\/j.intimp.2026.117293_bb0950","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120280","article-title":"Modulation of the CEACAM1\/TIM3 pathway by traditional Chinese medicine Xuebijing alleviates sepsis-induced acute lung injury through inhibition of NETs formation","volume":"353","author":"Zhang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.intimp.2026.117293_bb0955","article-title":"Advances in infection-immunity mechanisms and molecular regulatory networks in severe pneumonia-associated lung injury","volume":"17","author":"Zhao","year":"2026","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0960","article-title":"Natural products in treating sepsis-associated lung and liver injuries by mediating ferroptosis, current progress, and future perspective","volume":"17","author":"Li","year":"2026","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0965","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70101","article-title":"The emerging role of neutrophil extracellular traps in autoimmune and autoinflammatory diseases","volume":"6","author":"Zeng","year":"2025","journal-title":"MedComm"},{"issue":"6","key":"10.1016\/j.intimp.2026.117293_bb0970","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1159\/000547633","article-title":"Traditional Chinese medicine formulas for the treatment of Sepsis-induced acute lung injury: a review","volume":"110","author":"Sun","year":"2025","journal-title":"Pharmacology"},{"issue":"3","key":"10.1016\/j.intimp.2026.117293_bb0975","doi-asserted-by":"crossref","DOI":"10.1007\/s10495-026-02316-z","article-title":"LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate\/MCT1\/AMPK\/mTOR axis","volume":"31","author":"Chen","year":"2026","journal-title":"Apoptosis"},{"issue":"10","key":"10.1016\/j.intimp.2026.117293_bb0980","doi-asserted-by":"crossref","DOI":"10.1177\/03000605221127099","article-title":"Association between tissue human neutrophil peptide 1\u20133 levels and cardiovascular phenotype: a prospective, longitudinal cohort study","volume":"50","author":"Abu Fanne","year":"2022","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.intimp.2026.117293_bb0985","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1022401","article-title":"Platelets\u2019 morphology, metabolic profile, exocytosis, and heterotypic aggregation with leukocytes in relation to severity and mortality of COVID-19-patients","volume":"13","author":"Yasseen","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.intimp.2026.117293_bb0990","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1577580","article-title":"Mechanistic insights into traditional Chinese medicine for viral pneumonia treatment: signaling pathway perspectives","volume":"16","author":"Zheng","year":"2025","journal-title":"Front. Pharmacol."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926011409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926011409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:41:08Z","timestamp":1790437268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926011409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":198,"alternative-id":["S1567576926011409"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117293","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Traditional Chinese medicine for neutrophil-mediated acute lung injury: from single-mechanism targeting to multi-mechanism synergistic regulation","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117293","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117293"}}