{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:01:57Z","timestamp":1791468117208,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["2408085QH246"],"award-info":[{"award-number":["2408085QH246"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82500888"],"award-info":[{"award-number":["82500888"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.intimp.2026.117466","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:03:39Z","timestamp":1790611419000},"page":"117466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["m5C demethylase TET2 promotes autophagy and alleviates podocyte injury in diabetic nephropathy by regulating RRAGC"],"prefix":"10.1016","volume":"190","author":[{"given":"Yu","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2026.117466_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115670","article-title":"Podocyte injury of diabetic nephropathy: novel mechanism discovery and therapeutic prospects","volume":"168","author":"Li","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"7\u20138","key":"10.1016\/j.intimp.2026.117466_bb0010","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s12272-025-01555-z","article-title":"Targeting NF-\u03baB in diabetic nephropathy: exploring the therapeutic potential of phytoconstituents","volume":"48","author":"Abhirami","year":"2025","journal-title":"Arch. Pharm. Res."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0015","doi-asserted-by":"crossref","DOI":"10.3390\/nu13010241","article-title":"Effects of high glucose and lipotoxicity on diabetic podocytes","volume":"13","author":"Nakamichi","year":"2021","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.intimp.2026.117466_bb0020","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1016\/j.ymthe.2022.02.021","article-title":"Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma","volume":"30","author":"Yang","year":"2022","journal-title":"Mol. Ther."},{"key":"10.1016\/j.intimp.2026.117466_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103439","article-title":"Podocyte SIRP\u03b1 reduction in diabetic nephropathy aggravates podocyte injury by promoting pyruvate kinase M2 nuclear translocation","volume":"78","author":"Chen","year":"2024","journal-title":"Redox Biol."},{"issue":"18","key":"10.1016\/j.intimp.2026.117466_bb0030","doi-asserted-by":"crossref","first-page":"18037","DOI":"10.1021\/acsnano.3c04671","article-title":"Enhanced biohomogeneous composite membrane-encapsulated nanoplatform with podocyte targeting for precise and safe treatment of diabetic nephropathy","volume":"17","author":"Fan","year":"2023","journal-title":"ACS Nano"},{"issue":"11","key":"10.1016\/j.intimp.2026.117466_bb0035","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/s41580-024-00757-5","article-title":"Mechanisms of autophagy-lysosome dysfunction in neurodegenerative diseases","volume":"25","author":"Nixon","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"5","key":"10.1016\/j.intimp.2026.117466_bb0040","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1080\/15548627.2023.2286128","article-title":"Circ-0000953 deficiency exacerbates podocyte injury and autophagy disorder by targeting Mir665-3p-Atg4b in diabetic nephropathy","volume":"20","author":"Liu","year":"2024","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.intimp.2026.117466_bb0045","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/s41594-023-01163-9","article-title":"Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging","volume":"31","author":"Guo","year":"2024","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"5","key":"10.1016\/j.intimp.2026.117466_bb0050","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1038\/s41401-022-01021-2","article-title":"Hepatocellular carcinoma cells loss lenvatinib efficacy in vitro through autophagy and hypoxia response-derived neuropilin-1 degradation","volume":"44","author":"Fern\u00e1ndez-Palanca","year":"2023","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0055","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12929-023-00899-2","article-title":"The role of autophagy in viral infections","volume":"30","author":"Chen","year":"2023","journal-title":"J. Biomed. Sci."},{"issue":"20","key":"10.1016\/j.intimp.2026.117466_bb0060","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.165817","article-title":"Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy","volume":"8","author":"Lu","year":"2023","journal-title":"JCI Insight"},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0065","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12943-024-02041-8","article-title":"The role of RNA methylation in tumor immunity and its potential in immunotherapy","volume":"23","author":"Li","year":"2024","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0070","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/s41392-023-01638-7","article-title":"RNA modification in cardiovascular disease: implications for therapeutic interventions","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0075","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s40364-022-00362-8","article-title":"Biological roles of RNA m(5)C modification and its implications in Cancer immunotherapy","volume":"10","author":"Song","year":"2022","journal-title":"Biomark. Res."},{"issue":"28","key":"10.1016\/j.intimp.2026.117466_bb0080","article-title":"Metabolic recoding of NSUN2-mediated m(5)C modification promotes the progression of colorectal Cancer via the NSUN2\/YBX1\/m(5)C-ENO1 positive feedback loop","volume":"11","author":"Chen","year":"2024","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.intimp.2026.117466_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.109055","article-title":"RNA methyltransferase NSUN2-mediated m5C methylation promotes Cr(VI)-induced malignant transformation and lung cancer by accelerating metabolism reprogramming","volume":"192","author":"Zhang","year":"2024","journal-title":"Environ. Int."},{"issue":"12","key":"10.1016\/j.intimp.2026.117466_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011808","article-title":"NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication","volume":"19","author":"Feng","year":"2023","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0095","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s12967-022-03427-2","article-title":"5-methylcytosine RNA methyltransferases and their potential roles in cancer","volume":"20","author":"Li","year":"2022","journal-title":"J. Transl. Med."},{"issue":"4","key":"10.1016\/j.intimp.2026.117466_bb0100","doi-asserted-by":"crossref","DOI":"10.1111\/1440-1681.70026","article-title":"NSUN3 aggravates Sepsis-associated acute kidney injury by stabilising TIFA mRNA through m5C","volume":"52","author":"Zhang","year":"2025","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"12","key":"10.1016\/j.intimp.2026.117466_bb0105","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1681\/ASN.0000000000000441","article-title":"B-cell epigenetic modulation of IgA response by 5-azacytidine and IgA nephropathy","volume":"35","author":"Yu","year":"2024","journal-title":"J. Am. Soc. Nephrol."},{"issue":"Pt 3","key":"10.1016\/j.intimp.2026.117466_bb0110","article-title":"Tet2 modulates M2 macrophage polarization via mRNA 5-methylcytosine in allergic rhinitis","volume":"143","author":"Fan","year":"2024","journal-title":"Int. Immunopharmacol."},{"issue":"8","key":"10.1016\/j.intimp.2026.117466_bb0115","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.stem.2023.07.001","article-title":"TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal","volume":"30","author":"Li","year":"2023","journal-title":"Cell Stem Cell"},{"issue":"11","key":"10.1016\/j.intimp.2026.117466_bb0120","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S2213-8587(21)00243-6","article-title":"Effect of dapagliflozin on urinary albumin excretion in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the DAPA-CKD trial","volume":"9","author":"Jongs","year":"2021","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.intimp.2026.117466_bb0125","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.2147\/DMSO.S366907","article-title":"Clinical significance of glomerular autophagy in evaluation of diabetic kidney disease progression","volume":"15","author":"Wang","year":"2022","journal-title":"Diabetes Metab. Syndr. Obes.: Targets Ther."},{"issue":"23","key":"10.1016\/j.intimp.2026.117466_bb0130","doi-asserted-by":"crossref","DOI":"10.3390\/cells12232691","article-title":"The role of autophagy in type 2 diabetic kidney disease management","volume":"12","author":"Tseng","year":"2023","journal-title":"Cells"},{"issue":"19","key":"10.1016\/j.intimp.2026.117466_bb0135","article-title":"Deficiency of nuclear receptor coactivator 3 aggravates diabetic kidney disease by impairing podocyte autophagy","volume":"11","author":"Xie","year":"2024","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.intimp.2026.117466_bb0140","first-page":"1","article-title":"Amphibian-derived peptide OA-AL14 alleviates UVB-induced skin photoaging via autophagy activation mediated by the AMPK\/mTOR pathway","author":"Peng","year":"2026","journal-title":"Integ. Zool."},{"issue":"3","key":"10.1016\/j.intimp.2026.117466_bb0145","doi-asserted-by":"crossref","first-page":"748","DOI":"10.24272\/j.issn.2095-8137.2025.499","article-title":"First identification of an amphibian-derived peptide with antivascular aging activity","volume":"47","author":"Xin","year":"2026","journal-title":"Zool. Res."},{"issue":"5","key":"10.1016\/j.intimp.2026.117466_bb0150","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.24272\/j.issn.2095-8137.2025.211","article-title":"Ultra-short cyclic peptide CyRL-QN15 acts as a TLR4 antagonist to expedite oral ulcer healing","volume":"46","author":"Ze-Qiong","year":"2025","journal-title":"Zool. Res."},{"issue":"10","key":"10.1016\/j.intimp.2026.117466_bb0155","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1093\/nar\/2.10.1653","article-title":"The methylation state of poly A-containing messenger RNA from cultured hamster cells","volume":"2","author":"Dubin","year":"1975","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.intimp.2026.117466_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.217059","article-title":"NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization","volume":"597","author":"Zhao","year":"2024","journal-title":"Cancer Lett."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0165","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/s12944-025-02652-0","article-title":"NSUN2 knockdown ameliorates hepatic glucose and lipid metabolism disorders in type 2 diabetes mellitus through the inhibition of ACSL6 m5C methylation","volume":"24","author":"Jiang","year":"2025","journal-title":"Lipids Health Dis."},{"issue":"1","key":"10.1016\/j.intimp.2026.117466_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15476286.2023.2290769","article-title":"Circular RNAs in non-alcoholic fatty liver disease: functions and clinical significance","volume":"21","author":"Zeng","year":"2024","journal-title":"RNA Biol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117466_bb0175","doi-asserted-by":"crossref","first-page":"183","DOI":"10.20517\/jtgg.2023.23","article-title":"Obesity associated cancers, genetics, epigenetics and elephants","volume":"7","author":"Berger","year":"2023","journal-title":"J. Transl. Genet. Genom."},{"issue":"3","key":"10.1016\/j.intimp.2026.117466_bb0180","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines14030687","article-title":"Integrative transcriptomics and machine learning reveal the association of CBX4 with inflammation in ulcerative colitis as a potential epigenetic regulator","volume":"14","author":"Ma","year":"2026","journal-title":"Biomedicines"},{"issue":"2","key":"10.1016\/j.intimp.2026.117466_bb0185","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202403014R","article-title":"m6A demethylase Fto inhibited macrophage activation and glycolysis in diabetic nephropathy via m6A\/Npas2\/Hif-1alpha axis","volume":"39","author":"Zhu","year":"2025","journal-title":"FASEB J."},{"issue":"16","key":"10.1016\/j.intimp.2026.117466_bb0190","doi-asserted-by":"crossref","first-page":"4995","DOI":"10.1021\/acs.jafc.2c00863","article-title":"Punicalagin attenuates neuronal apoptosis by upregulating 5-Hydroxymethylcytosine in the diabetic mouse brain","volume":"70","author":"He","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.intimp.2026.117466_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2025.117440","article-title":"Upregulation of BNIP3 alleviates renal tubular cell injury by activating mitophagy in diabetic nephropathy","volume":"243","author":"Hu","year":"2026","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117466_bb0200","doi-asserted-by":"crossref","first-page":"10051","DOI":"10.3389\/ebm.2024.10051","article-title":"Triptolide decreases podocytes permeability by regulating TET2-mediated hydroxymethylation of ZO-1","volume":"249","author":"Tang","year":"2024","journal-title":"Exp. Biol. Med. (Maywood)"},{"issue":"4","key":"10.1016\/j.intimp.2026.117466_bb0205","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.kint.2022.06.010","article-title":"Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease","volume":"102","author":"Shahzad","year":"2022","journal-title":"Kidney Int."},{"key":"10.1016\/j.intimp.2026.117466_bb0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2024.150837","article-title":"Scutellarin alleviated ulcerative colitis through gut microbiota-mediated cAMP\/PKA\/NF-\u03baB pathway","volume":"735","author":"Li","year":"2024","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.intimp.2026.117466_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156677","article-title":"Modified huangfeng decoction alleviates diabetic nephropathy by activating autophagy and regulating the gut microbiota","volume":"141","author":"Ni","year":"2025","journal-title":"Phytomedicine"},{"issue":"12","key":"10.1016\/j.intimp.2026.117466_bb0220","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1080\/15548627.2022.2048432","article-title":"TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss","volume":"18","author":"Yang","year":"2022","journal-title":"Autophagy"},{"issue":"7","key":"10.1016\/j.intimp.2026.117466_bb0225","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1007\/s10439-015-1491-4","article-title":"Low shear stress inhibited endothelial cell autophagy through TET2 downregulation","volume":"44","author":"Yang","year":"2016","journal-title":"Ann. Biomed. Eng."},{"issue":"8","key":"10.1016\/j.intimp.2026.117466_bb0230","first-page":"1102","article-title":"A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan, Nat","volume":"4","author":"Ortega-Molina","year":"2024","journal-title":"Aging"},{"issue":"2","key":"10.1016\/j.intimp.2026.117466_bb0235","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202051239","article-title":"Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis","volume":"22","author":"Fong","year":"2021","journal-title":"EMBO Rep."},{"issue":"3","key":"10.1016\/j.intimp.2026.117466_bb0240","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13360","article-title":"Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation","volume":"56","author":"Xia","year":"2023","journal-title":"Cell Prolif."},{"issue":"6","key":"10.1016\/j.intimp.2026.117466_bb0245","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.24272\/j.issn.2095-8137.2024.134","article-title":"Peptide cy (RL-QN15) accelerates hair regeneration in diabetic mice by binding to the Frizzled-7 receptor","volume":"45","author":"Wu","year":"2024","journal-title":"Zool. Res."},{"issue":"18","key":"10.1016\/j.intimp.2026.117466_bb0250","doi-asserted-by":"crossref","first-page":"19503","DOI":"10.1021\/acs.jmedchem.5c01734","article-title":"Cyclic heptapeptide FZ1 acts as an integrin alphavbeta3 agonist to facilitate diabetic skin wound healing by enhancing angiogenesis","volume":"68","author":"Wang","year":"2025","journal-title":"J. Med. Chem."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926013135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926013135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:25:33Z","timestamp":1791465933000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926013135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":50,"alternative-id":["S1567576926013135"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117466","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"m5C demethylase TET2 promotes autophagy and alleviates podocyte injury in diabetic nephropathy by regulating RRAGC","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117466","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117466"}}