{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:38:10Z","timestamp":1792791490995,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014895","name":"Southwest Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Immunopharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.intimp.2026.117572","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:21:17Z","timestamp":1792718477000},"page":"117572","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Ginsenoside Re attenuates ferroptosis induced by hepatic ischemia-reperfusion injury via the BAP1\/SLC7A11 axis"],"prefix":"10.1016","volume":"191","author":[{"given":"Tingfeng","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danna","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonghao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangkun","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RunSheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeyu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinpeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baolin","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxing","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenguang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.intimp.2026.117572_bb0005","article-title":"Hepatic ischemia-reperfusion injury: protective approaches and treatment","volume":"17","author":"Singh","year":"2024","journal-title":"Curr. Mol. Pharmacol."},{"issue":"4","key":"10.1016\/j.intimp.2026.117572_bb0010","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3350\/cmh.2024.0222","article-title":"Current status and perspective on molecular targets and therapeutic intervention strategy in hepatic ischemia-reperfusion injury","volume":"30","author":"Liu","year":"2024","journal-title":"Clin. Mol. Hepatol."},{"issue":"2","key":"10.1016\/j.intimp.2026.117572_bb0015","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/gutjnl-2025-336400","article-title":"SMYD2-mediated methylation of STAT1 protects against hepatic ischaemia\/reperfusion injury by blocking JAK-STAT1 signalling pathways","volume":"75","author":"Yang","year":"2026","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.intimp.2026.117572_bb0020","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3390\/jcm9010253","article-title":"Ischemia and reperfusion injury in kidney transplantation: relevant mechanisms in injury and repair","volume":"9","author":"Nieuwenhuijs-Moeke","year":"2020","journal-title":"J. Clin. Med."},{"issue":"4","key":"10.1016\/j.intimp.2026.117572_bb0025","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1152\/physrev.00022.2018","article-title":"Fundamental mechanisms of regulated cell death and implications for heart disease","volume":"99","author":"Del Re","year":"2019","journal-title":"Physiol. Rev."},{"issue":"11","key":"10.1016\/j.intimp.2026.117572_bb0030","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3390\/antiox11112196","article-title":"Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury","volume":"11","author":"Pan","year":"2022","journal-title":"Antioxidants (Basel)"},{"issue":"1","key":"10.1016\/j.intimp.2026.117572_bb0035","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/s41420-023-01387-0","article-title":"Autophagy in hepatic ischemia-reperfusion injury","volume":"9","author":"Mao","year":"2023","journal-title":"Cell Death Discov."},{"issue":"5","key":"10.1016\/j.intimp.2026.117572_bb0040","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.intimp.2026.117572_bb0045","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","article-title":"Ferroptosis: past, present and future","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.intimp.2026.117572_bb0050","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.intimp.2026.117572_bb0055","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","article-title":"Ferroptosis: molecular mechanisms and health implications","volume":"31","author":"Tang","year":"2021","journal-title":"Cell Res."},{"issue":"6","key":"10.1016\/j.intimp.2026.117572_bb0060","doi-asserted-by":"crossref","first-page":"368","DOI":"10.21037\/atm-21-6942","article-title":"The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review","volume":"10","author":"Liu","year":"2022","journal-title":"Ann. Transl. Med."},{"issue":"6","key":"10.1016\/j.intimp.2026.117572_bb0065","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1111\/ajt.15773","article-title":"Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis","volume":"20","author":"Yamada","year":"2020","journal-title":"Am. J. Transplant."},{"issue":"3","key":"10.1016\/j.intimp.2026.117572_bb0070","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3892\/mmr.2021.11864","article-title":"Ferroptosis in hepatic ischemia-reperfusion injury: Regulatory mechanisms and new methods for therapy (Review)","volume":"23","author":"Luo","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.intimp.2026.117572_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.111545","article-title":"Potential effects of different cell death inhibitors in protecting against ischemia-reperfusion injury in steatotic liver","volume":"128","author":"Junzhe","year":"2024","journal-title":"Int. Immunopharmacol."},{"issue":"9198","key":"10.1016\/j.intimp.2026.117572_bb0080","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0140-6736(99)06457-0","article-title":"Herb-drug interactions","volume":"355","author":"Fugh-Berman","year":"2000","journal-title":"Lancet"},{"issue":"16","key":"10.1016\/j.intimp.2026.117572_bb0085","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1093\/jnci\/djt181","article-title":"Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2","volume":"105","author":"Barton","year":"2013","journal-title":"J. Natl. Cancer Inst."},{"issue":"6 Pt 1","key":"10.1016\/j.intimp.2026.117572_bb0090","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.biotechadv.2015.03.001","article-title":"Biosynthesis and biotechnological production of ginsenosides","volume":"33","author":"Kim","year":"2015","journal-title":"Biotechnol. Adv."},{"issue":"3","key":"10.1016\/j.intimp.2026.117572_bb0095","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1039\/c0np00057d","article-title":"Isolation and analysis of ginseng: advances and challenges","volume":"28","author":"Qi","year":"2011","journal-title":"Nat. Prod. Rep."},{"issue":"12","key":"10.1016\/j.intimp.2026.117572_bb0100","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.3390\/ijms20122951","article-title":"Phenolic compounds and ginsenosides in ginseng shoots and their antioxidant and anti-inflammatory capacities in LPS-induced RAW264.7 mouse macrophages","volume":"20","author":"Yao","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.intimp.2026.117572_bb0105","article-title":"Pharmacological properties of ginsenoside Re","volume":"13","author":"Gao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.intimp.2026.117572_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154119","article-title":"A comprehensive system review of pharmacological effects and relative mechanisms of Ginsenoside Re: recent advances and future perspectives","volume":"102","author":"Cai","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.intimp.2026.117572_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.532041","article-title":"Ginsenoside Re treatment attenuates myocardial hypoxia\/reoxygenation injury by inhibiting HIF-1\u03b1 ubiquitination","volume":"11","author":"Sun","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"12","key":"10.1016\/j.intimp.2026.117572_bb0120","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1002\/ejhf.3068","article-title":"Qiliqiangxin: a multifaceted holistic treatment for heart failure or a pharmacological probe for the identification of cardioprotective mechanisms?","volume":"25","author":"Packer","year":"2023","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.intimp.2026.117572_bb0125","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9003603","article-title":"Ginsenoside Re improves inflammation and fibrosis in hepatic tissue by upregulating PPAR\u03b3 expression and inhibiting oxidative stress in db\/db mice","volume":"2021","author":"Jiang","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"3","key":"10.1016\/j.intimp.2026.117572_bb0130","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nrc3459","article-title":"BAP1 and cancer","volume":"13","author":"Carbone","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"6101","key":"10.1016\/j.intimp.2026.117572_bb0135","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1126\/science.1221711","article-title":"Loss of the tumor suppressor BAP1 causes myeloid transformation","volume":"337","author":"Dey","year":"2012","journal-title":"Science"},{"issue":"10","key":"10.1016\/j.intimp.2026.117572_bb0140","doi-asserted-by":"crossref","first-page":"6232","DOI":"10.1093\/nar\/gku274","article-title":"The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex","volume":"42","author":"Ji","year":"2014","journal-title":"Nucleic Acids Res."},{"issue":"19","key":"10.1016\/j.intimp.2026.117572_bb0145","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1002\/pmic.201400013","article-title":"MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain","volume":"14","author":"Baymaz","year":"2014","journal-title":"Proteomics"},{"issue":"21","key":"10.1016\/j.intimp.2026.117572_bb0150","doi-asserted-by":"crossref","first-page":"5071","DOI":"10.1128\/MCB.00396-10","article-title":"Affar el B. The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression","volume":"30","author":"Yu","year":"2010","journal-title":"Mol. Cell. Biol."},{"issue":"8","key":"10.1016\/j.intimp.2026.117572_bb0155","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1128\/MCB.01517-08","article-title":"Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1","volume":"29","author":"Misaghi","year":"2009","journal-title":"Mol. Cell. Biol."},{"issue":"49","key":"10.1016\/j.intimp.2026.117572_bb0160","doi-asserted-by":"crossref","first-page":"34179","DOI":"10.1074\/jbc.M109.046755","article-title":"The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1","volume":"284","author":"Machida","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"7295","key":"10.1016\/j.intimp.2026.117572_bb0165","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/nature08966","article-title":"Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB","volume":"465","author":"Scheuermann","year":"2010","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.intimp.2026.117572_bb0170","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1038\/s41556-018-0178-0","article-title":"BAP1 links metabolic regulation of ferroptosis to tumour suppression","volume":"20","author":"Zhang","year":"2018","journal-title":"Nat. Cell Biol."},{"issue":"6","key":"10.1016\/j.intimp.2026.117572_bb0230","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3390\/antiox13060661","article-title":"Lianweng granules alleviate intestinal barrier damage via the IL-6\/STAT3\/PI3K\/AKT signaling pathway with dampness-heat syndrome diarrhea","volume":"13","author":"Lv","year":"2024","journal-title":"Antioxidants (Basel)"},{"issue":"1","key":"10.1016\/j.intimp.2026.117572_bb0235","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41392-022-01248-9","article-title":"Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression","volume":"8","author":"Tan","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"8","key":"10.1016\/j.intimp.2026.117572_bb0225","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1080\/15384101.2019.1597506","article-title":"Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1","volume":"18","author":"Zhang","year":"2019","journal-title":"Cell Cycle"},{"issue":"21","key":"10.1016\/j.intimp.2026.117572_bb0175","doi-asserted-by":"crossref","first-page":"12942","DOI":"10.3390\/ijms232112942","article-title":"Molecular mechanisms of ischaemia-reperfusion injury and regeneration in the liver-shock and surgery-associated changes","volume":"23","author":"Pretzsch","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.intimp.2026.117572_bb0180","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jcmgh.2023.03.003","article-title":"Mechanistic insight and clinical implications of ischemia\/reperfusion injury post liver transplantation","volume":"15","author":"Liu","year":"2023","journal-title":"Cell Mol. Gastroenterol. Hepatol."},{"issue":"3","key":"10.1016\/j.intimp.2026.117572_bb0210","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s41418-022-00941-0","article-title":"The multifaceted role of ferroptosis in liver disease","volume":"29","author":"Chen","year":"2022","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.intimp.2026.117572_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2026.04.024","article-title":"Ferroptosis inhibition enhances liver and lung graft function","author":"Veeckmans","year":"2026","journal-title":"Cell"},{"key":"10.1016\/j.intimp.2026.117572_bb0220","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.freeradbiomed.2025.12.002","article-title":"EMP1-driven ferroptosis in liver sinusoidal endothelial cells exacerbates hepatic ischemia-reperfusion injury via P38 MAPK","volume":"244","author":"Yang","year":"2026","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.intimp.2026.117572_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154681","article-title":"Ginsenoside Re attenuates myocardial ischemia\/reperfusion induced ferroptosis via miR-144-3p\/SLC7A11","volume":"113","author":"Ye","year":"2023","journal-title":"Phytomedicine"},{"issue":"36","key":"10.1016\/j.intimp.2026.117572_bb0190","doi-asserted-by":"crossref","first-page":"19838","DOI":"10.1021\/acs.jafc.4c04394","article-title":"Ginsenoside Re prevents depression-like behaviors via inhibition of inflammation, oxidative stress, and activating BDNF\/TrkB\/ERK\/CREB signaling: an in vivo and in vitro study","volume":"72","author":"Chen","year":"2024","journal-title":"J. Agric. Food Chem."},{"issue":"2","key":"10.1016\/j.intimp.2026.117572_bb0195","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jgr.2021.11.009","article-title":"Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489\/myd88\/NF-\u03baB pathway","volume":"47","author":"Sun","year":"2023","journal-title":"J. Ginseng Res."},{"issue":"3","key":"10.1016\/j.intimp.2026.117572_bb0200","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s11481-023-10073-y","article-title":"Ginsenoside Re mitigates photooxidative stress-mediated photoreceptor degeneration and retinal inflammation","volume":"18","author":"Chang","year":"2023","journal-title":"J. NeuroImmune Pharmacol."},{"issue":"11","key":"10.1016\/j.intimp.2026.117572_bb0205","doi-asserted-by":"crossref","first-page":"5088","DOI":"10.1002\/ptr.8309","article-title":"Ginsenoside Re inhibits non-small cell lung cancer progression by suppressing macrophage M2 polarization induced by AMPK\u03b11\/STING positive feedback loop","volume":"38","author":"Tang","year":"2024","journal-title":"Phytother. Res."}],"container-title":["International Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926014207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567576926014207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:46:19Z","timestamp":1792788379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567576926014207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":47,"alternative-id":["S1567576926014207"],"URL":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117572","relation":{},"ISSN":["1567-5769"],"issn-type":[{"value":"1567-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ginsenoside Re attenuates ferroptosis induced by hepatic ischemia-reperfusion injury via the BAP1\/SLC7A11 axis","name":"articletitle","label":"Article Title"},{"value":"International Immunopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.intimp.2026.117572","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117572"}}