{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:45:29Z","timestamp":1792727129197,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F31MH124372"],"award-info":[{"award-number":["F31MH124372"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01DA049449"],"award-info":[{"award-number":["R01DA049449"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01DA049545"],"award-info":[{"award-number":["R01DA049545"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01DC006213"],"award-info":[{"award-number":["R01DC006213"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS117061"],"award-info":[{"award-number":["R01NS117061"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21DC019193"],"award-info":[{"award-number":["R21DC019193"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.isci.2022.104284","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T12:56:01Z","timestamp":1650632161000},"page":"104284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Self-directed orofacial grooming promotes social attraction in mice via chemosensory communication"],"prefix":"10.1016","volume":"25","author":[{"given":"Yun-Feng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Janke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janardhan P.","family":"Bhattarai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel W.","family":"Wesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5027-9623","authenticated-orcid":false,"given":"Minghong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2022.104284_bib1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.neuron.2005.10.022","article-title":"Olfaction: diverse species, conserved principles","volume":"48","author":"Ache","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.isci.2022.104284_bib2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0166-4328(87)90243-9","article-title":"Deafferentation does not disrupt natural rules of action syntax","volume":"23","author":"Berridge","year":"1987","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.isci.2022.104284_bib3","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1098\/rstb.2006.1931","article-title":"Mammalian social odours: attraction and individual recognition","volume":"361","author":"Brennan","year":"2006","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.isci.2022.104284_bib4","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1037\/0735-7036.114.3.281","article-title":"Do California ground squirrels (Spermophilus beecheyi) use ritualized syntactic cephalocaudal grooming as an agonistic signal?","volume":"114","author":"Bursten","year":"2000","journal-title":"J.\u00a0Comp. Psychol."},{"key":"10.1016\/j.isci.2022.104284_bib5","series-title":"Neurobiology of Grooming Behavior","first-page":"19","article-title":"Self-grooming as a form of olfactory communication in meadow voles and prairie voles (Microtus spp.)","author":"Ferkin","year":"2010"},{"key":"10.1016\/j.isci.2022.104284_bib6","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1046\/j.1439-0310.2001.00725.x","article-title":"Self-grooming as a tactic used by prairie voles Microtus ochrogaster to enhance\u00a0sexual communication","volume":"107","author":"Ferkin","year":"2001","journal-title":"Ethology"},{"key":"10.1016\/j.isci.2022.104284_bib7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1006\/anbe.1996.0084","article-title":"Self-grooming as a sexually dimorphic communicative behaviour in meadow voles, Microtus pennsylvanicus","volume":"51","author":"Ferkin","year":"1996","journal-title":"Anim. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib8","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0018-506X(85)90020-0","article-title":"Harderian letdown in male Mongolian gerbils (Meriones unguiculatus) contributes to proceptive behavior","volume":"19","author":"Harriman","year":"1985","journal-title":"Horm. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib9","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0031-9384(00)00320-6","article-title":"Prepubertal genital grooming and penile erections in relation to sexual behavior of rats","volume":"71","author":"Hernandez-Gonzalez","year":"2000","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib10","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.cell.2014.07.049","article-title":"Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets","volume":"158","author":"Hong","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.isci.2022.104284_bib11","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1038\/nprot.2007.367","article-title":"Analyzing grooming microstructure in neurobehavioral experiments","volume":"2","author":"Kalueff","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.isci.2022.104284_bib12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nrn.2015.8","article-title":"Neurobiology of rodent self-grooming and its value for translational neuroscience","volume":"17","author":"Kalueff","year":"2016","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.isci.2022.104284_bib13","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.yhbeh.2007.08.012","article-title":"The combined role of the main olfactory and vomeronasal systems in social communication in mammals","volume":"52","author":"Kelliher","year":"2007","journal-title":"Horm. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/0018-506X(79)90023-0","article-title":"Salivary cues in the mouse: a preliminary study","volume":"12","author":"Lee","year":"1979","journal-title":"Horm. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib15","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.conb.2018.07.005","article-title":"Neural coding of sex-specific social information in the mouse brain","volume":"53","author":"Li","year":"2018","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.isci.2022.104284_bib16","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nn.2467","article-title":"A robust and high-throughput Cre reporting and characterization system for the whole mouse brain","volume":"13","author":"Madisen","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.isci.2022.104284_bib17","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/s41467-017-02534-9","article-title":"A neural basis for antagonistic control of feeding and compulsive behaviors","volume":"9","author":"Mangieri","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2022.104284_bib18","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/0003-3472(79)90027-7","article-title":"The attractiveness of Harderian gland smears to sexually naive and experienced male golden hamsters","volume":"27","author":"Payne","year":"1979","journal-title":"Anim. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib19","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0163-1047(81)91977-4","article-title":"Body temperature and autogrooming in the Mongolian gerbil, Meriones unguiculatus","volume":"33","author":"Pendergrass","year":"1981","journal-title":"Behav. Neural Biol."},{"key":"10.1016\/j.isci.2022.104284_bib20","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.05959","article-title":"Insights into mammalian biology from the wild house mouse Mus musculus","volume":"4","author":"Phifer-Rixey","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.isci.2022.104284_bib21","doi-asserted-by":"crossref","first-page":"3464","DOI":"10.1038\/s41596-020-0382-9","article-title":"A standardized social preference protocol for measuring social deficits in mouse models of autism","volume":"15","author":"Rein","year":"2020","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.isci.2022.104284_bib22","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0091-6773(74)90935-3","article-title":"Saliva lost by grooming: a major item in the rat's water economy","volume":"11","author":"Ritter","year":"1974","journal-title":"Behav. Biol."},{"key":"10.1016\/j.isci.2022.104284_bib23","doi-asserted-by":"crossref","first-page":"113548","DOI":"10.1016\/j.ygcen.2020.113548","article-title":"The Harderian gland: endocrine function and hormonal control","volume":"297","author":"Santillo","year":"2020","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.isci.2022.104284_bib24","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2183\/pjab.83.77","article-title":"Novel function of lipids as a pheromone from the Harderian gland of golden hamster","volume":"83","author":"Seyama","year":"2007","journal-title":"Proc. Jpn. Acad. Ser. B Phys. Biol. Sci."},{"key":"10.1016\/j.isci.2022.104284_bib25","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1006\/anbe.1997.0533","article-title":"Mole-rat harderian gland secretions inhibit aggression","volume":"54","author":"Shanas","year":"1997","journal-title":"Anim. Behav."},{"key":"10.1016\/j.isci.2022.104284_bib26","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/B978-012369454-6\/50015-7","article-title":"The secret world of wild mice","volume":"1","author":"Singleton","year":"2007","journal-title":"Mouse Biomed. Res."},{"key":"10.1016\/j.isci.2022.104284_bib27","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1007\/s00018-006-6109-4","article-title":"Parallel processing of social signals by the mammalian main and accessory olfactory systems","volume":"63","author":"Spehr","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.isci.2022.104284_bib28","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/physrev.1992.72.3.825","article-title":"Ethology and neurobiology of grooming behavior","volume":"72","author":"Spruijt","year":"1992","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.isci.2022.104284_bib29","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fnana.2012.00050","article-title":"Mutual influences between the main olfactory and vomeronasal systems in development and evolution","volume":"6","author":"Suarez","year":"2012","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.isci.2022.104284_bib30","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1002\/cne.22611","article-title":"Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage","volume":"519","author":"Suzukawa","year":"2011","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.isci.2022.104284_bib31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1749-6632.1988.tb38593.x","article-title":"Body temperature and grooming in the Mongolian gerbil","volume":"525","author":"Thiessen","year":"1988","journal-title":"Ann. N Y Acad. Sci."},{"key":"10.1016\/j.isci.2022.104284_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF00987746","article-title":"Harderian gland pheromone in the Mongolian gerbil Meriones unguiculatus","volume":"2","author":"Thiessen","year":"1976","journal-title":"J.\u00a0Chem. Ecol."},{"key":"10.1016\/j.isci.2022.104284_bib33","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.1523\/JNEUROSCI.1109-20.2020","article-title":"The tubular striatum","volume":"40","author":"Wesson","year":"2020","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.isci.2022.104284_bib34","first-page":"622","article-title":"The social significance of self-grooming in rats","volume":"29","author":"Wiepkema","year":"1979","journal-title":"Neth. J. Zool."},{"key":"10.1016\/j.isci.2022.104284_bib35","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.1439-0310.2002.00763.x","article-title":"Is self-grooming by male prairie voles a\u00a0predictor of mate choice?","volume":"108","author":"Wolff","year":"2002","journal-title":"Ethology"},{"key":"10.1016\/j.isci.2022.104284_bib36","series-title":"Pheromones and Animal Behaviour: Communication by Smell and Taste","author":"Wyatt","year":"2003"},{"key":"10.1016\/j.isci.2022.104284_bib37","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1113\/jphysiol.1991.sp018402","article-title":"Salivary secretion and grooming behaviour during heat exposure in freely moving rats","volume":"432","author":"Yanase","year":"1991","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.isci.2022.104284_bib38","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1038\/s41593-021-00952-z","article-title":"Ventral striatal islands of Calleja neurons control grooming in mice","volume":"24","author":"Zhang","year":"2021","journal-title":"Nat. Neurosci."}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004222005545?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004222005545?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T05:58:56Z","timestamp":1744869536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004222005545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S2589004222005545"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2022.104284","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Self-directed orofacial grooming promotes social attraction in mice via chemosensory communication","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2022.104284","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"104284"}}