{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:03:12Z","timestamp":1787500992053,"version":"build-2736575974"},"reference-count":65,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.isci.2024.109164","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T03:47:33Z","timestamp":1707450453000},"page":"109164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1"],"prefix":"10.1016","volume":"27","author":[{"given":"Matthew","family":"Triolo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soniya","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikita","family":"Larionov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Podini\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireille","family":"Khacho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2024.109164_bib1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/s41467-020-20760-6","article-title":"Perspectives on skeletal muscle stem cells","volume":"12","author":"Relaix","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2024.109164_bib2","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202002464R","article-title":"Reduced electron transport chain complex I protein abundance and function in Mfn2-deficient myogenic progenitors lead to oxidative stress and mitochondria swelling","volume":"35","author":"Luo","year":"2021","journal-title":"Faseb. J."},{"key":"10.1016\/j.isci.2024.109164_bib3","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.stem.2022.07.010","article-title":"The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells","volume":"29","author":"Baker","year":"2022","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.isci.2024.109164_bib4","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.stem.2022.09.002","article-title":"Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy","volume":"29","author":"Hong","year":"2022","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.isci.2024.109164_bib5","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1016\/j.celrep.2019.05.092","article-title":"Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function","volume":"27","author":"Yucel","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109164_bib6","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/stem.590","article-title":"Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells","volume":"29","author":"Mandal","year":"2011","journal-title":"Stem Cell."},{"key":"10.1016\/j.isci.2024.109164_bib7","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1242\/dev.091777","article-title":"Stem cell metabolism in tissue development and aging","volume":"140","author":"Shyh-Chang","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.isci.2024.109164_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.stem.2012.10.011","article-title":"Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells","volume":"12","author":"Takubo","year":"2013","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.isci.2024.109164_bib65","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.stem.2014.12.004","article-title":"The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells","volume":"16","author":"Ryall","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.isci.2024.109164_bib9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1139\/o04-040","article-title":"Bioenergetic remodeling during cellular differentiation: changes in cytochrome c oxidase regulation do not affect the metabolic phenotype","volume":"82","author":"Lyons","year":"2004","journal-title":"Biochem. Cell. Biol."},{"key":"10.1016\/j.isci.2024.109164_bib10","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0005-2728(98)00105-4","article-title":"Interactions between bioenergetics and mitochondrial biogenesis","volume":"1365","author":"Leary","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2024.109164_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070772","article-title":"Low glucose but not galactose enhances oxidative mitochondrial metabolism in C2C12 myoblasts and myotubes","volume":"8","author":"Elkalaf","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2024.109164_bib59","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1016\/j.celrep.2019.05.092","article-title":"Glucose metabolism drives histone acetylation landscape transitions that dictate muscle stem cell function","volume":"27","author":"Yucel","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109164_bib60","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/s41598-017-18658-3","article-title":"The effect of differentiation and TGF\u03b2 on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells","volume":"8","author":"Hoffmann","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.109164_bib64","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.celrep.2016.09.010","article-title":"MyoD regulates skeletal muscle oxidative metabolism cooperatively with alternative NF-\u03baB","volume":"17","author":"Shintaku","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109164_bib12","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/593267","article-title":"Mitochondria as a potential regulator of myogenesis","volume":"2013","author":"Wagatsuma","year":"2013","journal-title":"Sci. World J."},{"key":"10.1016\/j.isci.2024.109164_bib61","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1074\/jbc.275.4.2733","article-title":"Mitochondrial activity is involved in the regulation of myoblast differentiation through myogenin expression and activity of myogenic factors","volume":"275","author":"Rochard","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.isci.2024.109164_bib62","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/jcp.20539","article-title":"Mitochondrial activity regulates myoblast differentiation by control of c-Myc expression","volume":"207","author":"Seyer","year":"2006","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.isci.2024.109164_bib63","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3389\/fcell.2020.00480","article-title":"Mitochondrial function in muscle stem cell fates","volume":"8","author":"Bhattacharya","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2024.109164_bib13","series-title":"Mitochondrial Dynamics and its Involvement in Disease","author":"Chan","year":"2020"},{"key":"10.1016\/j.isci.2024.109164_bib14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cell.2006.06.025","article-title":"OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion","volume":"126","author":"Frezza","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.109164_bib15","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.cell.2013.08.032","article-title":"Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency","volume":"155","author":"Cogliati","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.109164_bib16","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.15252\/embj.201488349","article-title":"OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand","volume":"33","author":"Patten","year":"2014","journal-title":"EMBO J."},{"key":"10.1016\/j.isci.2024.109164_bib17","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jmedgenet-2015-103361","article-title":"Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygous OPA1 mutation","volume":"53","author":"Spiegel","year":"2016","journal-title":"J.\u00a0Med. Genet."},{"key":"10.1016\/j.isci.2024.109164_bib18","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1750-1172-7-46","article-title":"Dominant optic atrophy","volume":"7","author":"Lenaers","year":"2012","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.isci.2024.109164_bib19","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s00018-020-03662-0","article-title":"The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass","volume":"78","author":"Romanello","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.isci.2024.109164_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22158179","article-title":"Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging","volume":"22","author":"Leduc-Gaudet","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2024.109164_bib21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev-physiol-020518-114310","article-title":"Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging","volume":"81","author":"Hood","year":"2019","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.isci.2024.109164_bib22","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1038\/cdd.2010.48","article-title":"Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation","volume":"17","author":"De Palma","year":"2010","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.isci.2024.109164_bib23","doi-asserted-by":"crossref","first-page":"R927","DOI":"10.1152\/ajpregu.00502.2012","article-title":"Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation","volume":"305","author":"Kim","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.isci.2024.109164_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112434","article-title":"Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways","volume":"42","author":"Yasuda","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109164_bib25","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.15252\/embj.201696179","article-title":"OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance","volume":"36","author":"Pereira","year":"2017","journal-title":"EMBO J."},{"key":"10.1016\/j.isci.2024.109164_bib26","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.cmet.2017.04.021","article-title":"Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence","volume":"25","author":"Tezze","year":"2017","journal-title":"Cell Metabol."},{"key":"10.1016\/j.isci.2024.109164_bib27","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.168787","article-title":"A combination of metformin and galantamine exhibits synergistic benefits in the treatment of sarcopenia","volume":"8","author":"Tezze","year":"2023","journal-title":"JCI Insight"},{"key":"10.1016\/j.isci.2024.109164_bib28","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.cmet.2020.04.007","article-title":"Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1","volume":"31","author":"Herkenne","year":"2020","journal-title":"Cell Metabol."},{"key":"10.1016\/j.isci.2024.109164_bib29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s13046-022-02304-6","article-title":"Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth","volume":"41","author":"Zamberlan","year":"2022","journal-title":"J.\u00a0Exp. Clin. Cancer Res."},{"key":"10.1016\/j.isci.2024.109164_bib30","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/s41419-023-05768-2","article-title":"Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line","volume":"14","author":"Noguchi","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.isci.2024.109164_bib31","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1126\/science.1230381","article-title":"Supercomplex assembly determines electron flux in the mitochondrial electron transport chain","volume":"340","author":"Lapuente-Brun","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.isci.2024.109164_bib32","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1038\/ncomms3147","article-title":"A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle","volume":"4","author":"Ikeda","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2024.109164_bib33","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nature20157","article-title":"Mechanism of super-assembly of respiratory complexes III and IV","volume":"539","author":"Cogliati","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.isci.2024.109164_bib34","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1089\/ars.2020.8126","article-title":"Metabolic Regulation of Stem Cells and Differentiation: A Forkhead Box O Transcription Factor Perspective","volume":"34","author":"Ludikhuize","year":"2021","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.isci.2024.109164_bib35","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/15548627.2015.1115172","article-title":"Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts","volume":"12","author":"Sin","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.isci.2024.109164_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceca.2021.102517","article-title":"Cristae junction as a fundamental switchboard for mitochondrial ion signaling and bioenergetics","volume":"101","author":"Gottschalk","year":"2022","journal-title":"Cell Calcium"},{"key":"10.1016\/j.isci.2024.109164_bib37","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1146\/annurev-physiol-021115-105011","article-title":"Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function","volume":"78","author":"Pernas","year":"2016","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.isci.2024.109164_bib38","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1080\/15548627.2019.1591672","article-title":"Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation","volume":"15","author":"Baechler","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/j.isci.2024.109164_bib39","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.cellbi.2006.11.027","article-title":"A reducing redox environment promotes C2C12 myogenesis: implications for regeneration in aged muscle","volume":"31","author":"Hansen","year":"2007","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.isci.2024.109164_bib40","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.dib.2016.02.070","article-title":"Effect of mitochondrial fission inhibition on C2C12 differentiation","volume":"7","author":"Bloemberg","year":"2016","journal-title":"Data Brief"},{"key":"10.1016\/j.isci.2024.109164_bib41","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.molcel.2019.03.031","article-title":"ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2\u03b1 Axis","volume":"74","author":"Balsa","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.isci.2024.109164_bib42","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202050287","article-title":"Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish","volume":"21","author":"Garc\u00eda-Poyatos","year":"2020","journal-title":"EMBO Rep."},{"key":"10.1016\/j.isci.2024.109164_bib43","doi-asserted-by":"crossref","first-page":"eaba7509","DOI":"10.1126\/sciadv.aba7509","article-title":"Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q","volume":"6","author":"Calvo","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.isci.2024.109164_bib44","doi-asserted-by":"crossref","first-page":"7606","DOI":"10.1038\/s41598-017-08081-z","article-title":"Deficiency of COX7RP, a mitochondrial supercomplex assembly promoting factor, lowers blood glucose level in mice","volume":"7","author":"Shiba","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.109164_bib45","doi-asserted-by":"crossref","first-page":"e1515","DOI":"10.1038\/cddis.2014.458","article-title":"PGC-1\u03b1 buffers ROS-mediated removal of mitochondria during myogenesis","volume":"5","author":"Baldelli","year":"2014","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.isci.2024.109164_bib46","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/brain\/awm298","article-title":"OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes","volume":"131","author":"Amati-Bonneau","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.isci.2024.109164_bib47","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s13311-018-00674-4","article-title":"Diagnosis and Treatment of Mitochondrial Myopathies","volume":"15","author":"Ahmed","year":"2018","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.isci.2024.109164_bib48","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1471-213X-10-21","article-title":"Dynamics of muscle fibre growth during postnatal mouse development","volume":"10","author":"White","year":"2010","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.isci.2024.109164_bib49","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.cmet.2015.05.007","article-title":"The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage","volume":"21","author":"Varanita","year":"2015","journal-title":"Cell Metabol."},{"key":"10.1016\/j.isci.2024.109164_bib50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.bbabio.2018.01.005","article-title":"Eight human OPA1 isoforms, long and short: What are they for?","volume":"1859","author":"Del Dotto","year":"2018","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"10.1016\/j.isci.2024.109164_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.626117","article-title":"Mitochondrial OMA1 and OPA1 as Gatekeepers of Organellar Structure\/Function and Cellular Stress Response","volume":"9","author":"Gilkerson","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2024.109164_bib52","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1242\/jcs.159186","article-title":"OPA1 processing in cell death and disease - the long and short of it","volume":"129","author":"MacVicar","year":"2016","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.isci.2024.109164_bib53","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-4939-6771-1_3","article-title":"Primary Mouse Myoblast Purification using Magnetic Cell Separation","volume":"1556","author":"Sincennes","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.isci.2024.109164_bib54","doi-asserted-by":"crossref","DOI":"10.3791\/3266-v","article-title":"Visualization of mitochondrial respiratory function using cytochrome c oxidase\/succinate dehydrogenase (COX\/SDH) double-labeling histochemistry","author":"Ross","year":"2011","journal-title":"J.\u00a0Vis. Exp."},{"key":"10.1016\/j.isci.2024.109164_bib55","first-page":"Unit19.2","article-title":"Histochemical methods for the diagnosis of mitochondrial diseases","volume":"Chapter 19","author":"De Paepe","year":"2009","journal-title":"Curr. Protoc. Hum. Genet."},{"key":"10.1016\/j.isci.2024.109164_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.xpro.2023.102107","article-title":"Evaluating mitochondrial length, volume, and cristae ultrastructure in rare mouse adult stem cell populations","volume":"4","author":"Triolo","year":"2023","journal-title":"STAR Protoc."},{"key":"10.1016\/j.isci.2024.109164_bib57","doi-asserted-by":"crossref","first-page":"3550","DOI":"10.1038\/ncomms4550","article-title":"Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival","volume":"5","author":"Khacho","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2024.109164_bib58","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.stem.2016.04.015","article-title":"Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program","volume":"19","author":"Khacho","year":"2016","journal-title":"Cell Stem Cell"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224003857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224003857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:37:22Z","timestamp":1753868242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004224003857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":65,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S2589004224003857"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2024.109164","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2024.109164","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"109164"}}