{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:48:27Z","timestamp":1782539307554,"version":"3.54.5"},"reference-count":63,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009824","name":"FSH Society","doi-asserted-by":"publisher","award":["FSHS-82013-06"],"award-info":[{"award-number":["FSHS-82013-06"]}],"id":[{"id":"10.13039\/100009824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["108874\/B\/15\/Z"],"award-info":[{"award-number":["108874\/B\/15\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["WT 222352\/Z\/21\/Z"],"award-info":[{"award-number":["WT 222352\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/S002472\/1"],"award-info":[{"award-number":["MR\/S002472\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/P023215\/1"],"award-info":[{"award-number":["MR\/P023215\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013428","name":"Stichting Spieren voor Spieren","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012644","name":"Friends of FSH Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012644","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004243","name":"Prinses Beatrix Spierfonds","doi-asserted-by":"publisher","award":["15-23"],"award-info":[{"award-number":["15-23"]}],"id":[{"id":"10.13039\/501100004243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.isci.2024.109947","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T03:58:18Z","timestamp":1715140698000},"page":"109947","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Transcriptomic gene signatures measure satellite cell activity in muscular dystrophies"],"prefix":"10.1016","volume":"27","author":[{"given":"Elise N.","family":"Engquist","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo A.B.","family":"Joosten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baziel G.M.","family":"van Engelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.S.","family":"Banerji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9562-3072","authenticated-orcid":false,"given":"Peter S.","family":"Zammit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2024.109947_bib1","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1242\/dev.069088","article-title":"Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage","volume":"139","author":"Relaix","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.isci.2024.109947_bib2","doi-asserted-by":"crossref","first-page":"24","DOI":"10.2174\/1389202920666190116094736","article-title":"An Overview about the Biology of Skeletal Muscle Satellite Cells","volume":"20","author":"Forcina","year":"2019","journal-title":"Curr. Genomics"},{"key":"10.1016\/j.isci.2024.109947_bib3","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.9.2.493","article-title":"Satellite cell of skeletal muscle fibers","volume":"9","author":"Mauro","year":"1961","journal-title":"J.\u00a0Biophys. Biochem. Cytol."},{"key":"10.1016\/j.isci.2024.109947_bib4","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/jez.1402060314","article-title":"Satellite cells are mitotically quiescent in mature mouse muscle: an EM and radioautographic study","volume":"206","author":"Schultz","year":"1978","journal-title":"J.\u00a0Exp. Zool."},{"key":"10.1016\/j.isci.2024.109947_bib5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.cell.2005.05.010","article-title":"Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche","volume":"122","author":"Collins","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.109947_bib6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1083\/jcb.200312007","article-title":"Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?","volume":"166","author":"Zammit","year":"2004","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.isci.2024.109947_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.devcel.2024.03.017","article-title":"Three-dimensional imaging studies in mice identify cellular dynamics of skeletal muscle regeneration","volume":"59","author":"Collins","year":"2024","journal-title":"Dev. Cell"},{"key":"10.1016\/j.isci.2024.109947_bib8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ncb2015","article-title":"Muscle injury activates resident fibro\/adipogenic progenitors that facilitate myogenesis","volume":"12","author":"Joe","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.isci.2024.109947_bib9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.semcdb.2021.05.031","article-title":"Inflammation during post-injury skeletal muscle regeneration","volume":"119","author":"Panci","year":"2021","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2024.109947_bib10","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.042192","article-title":"Skeletal muscle in health and disease","volume":"13","author":"Morgan","year":"2020","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.isci.2024.109947_bib11","doi-asserted-by":"crossref","first-page":"5776","DOI":"10.1038\/s41467-019-13650-z","article-title":"Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7","volume":"10","author":"Marg","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2024.109947_bib12","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1038\/s41436-019-0532-z","article-title":"Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy","volume":"21","author":"Feichtinger","year":"2019","journal-title":"Genet. Med."},{"key":"10.1016\/j.isci.2024.109947_bib13","doi-asserted-by":"crossref","first-page":"e226","DOI":"10.1212\/NXG.0000000000000226","article-title":"Whole-exome sequencing identifies mutations in MYMK in a mild form of Carey-Fineman-Ziter syndrome","volume":"4","author":"Alrohaif","year":"2018","journal-title":"Neurol. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1136\/jmedgenet-2015-103620","article-title":"Deficiency of the myogenic factor MyoD causes a perinatally lethal fetal akinesia","volume":"53","author":"Watson","year":"2016","journal-title":"J.\u00a0Med. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2021.112906","article-title":"Defining and identifying satellite cell-opathies within muscular dystrophies and myopathies","volume":"411","author":"Ganassi","year":"2022","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.isci.2024.109947_bib16","doi-asserted-by":"crossref","DOI":"10.4081\/ejtm.2022.10064","article-title":"Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies","volume":"32","author":"Ganassi","year":"2022","journal-title":"Eur. J. Transl. Myol."},{"key":"10.1016\/j.isci.2024.109947_bib17","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20220284","article-title":"Impaired muscle stem cell function and abnormal myogenesis in acquired myopathies","volume":"43","author":"Deprez","year":"2023","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.isci.2024.109947_bib18","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1634\/stemcells.2007-0019","article-title":"Molecular signature of quiescent satellite cells in adult skeletal muscle","volume":"25","author":"Fukada","year":"2007","journal-title":"Stem Cell."},{"key":"10.1016\/j.isci.2024.109947_bib19","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.celrep.2017.10.080","article-title":"In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells","volume":"21","author":"Machado","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109947_bib20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.scr.2009.10.003","article-title":"An adult tissue-specific stem cell in its niche: a gene profiling analysis of in\u00a0vivo quiescent and activated muscle satellite cells","volume":"4","author":"Pallafacchina","year":"2010","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.isci.2024.109947_bib21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.celrep.2013.05.043","article-title":"Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging","volume":"4","author":"Liu","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109947_bib22","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nature16187","article-title":"Autophagy maintains stemness by preventing senescence","volume":"529","author":"Garcia-Prat","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.isci.2024.109947_bib23","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1038\/nm.4126","article-title":"Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice","volume":"22","author":"Lukjanenko","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.isci.2024.109947_bib24","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1038\/s42003-021-02810-x","article-title":"Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration","volume":"4","author":"McKellar","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.isci.2024.109947_bib25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/s41598-019-57110-6","article-title":"Single-cell transcriptional profiles in human skeletal muscle","volume":"10","author":"Rubenstein","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.109947_bib26","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13395-020-00236-3","article-title":"A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations","volume":"10","author":"De Micheli","year":"2020","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.isci.2024.109947_bib27","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1093\/hmg\/ddaa164","article-title":"Skeletal muscle regeneration in Facioscapulohumeral muscular dystrophy is correlated with pathological severity","volume":"29","author":"Banerji","year":"2020","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib28","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcad221","article-title":"The FSHD muscle-blood biomarker: a circulating transcriptomic biomarker for clinical severity in facioscapulohumeral muscular dystrophy","volume":"5","author":"Banerji","year":"2023","journal-title":"Brain Commun."},{"key":"10.1016\/j.isci.2024.109947_bib29","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1093\/hmg\/ddaa031","article-title":"Longitudinal measures of RNA expression and disease activity in FSHD muscle biopsies","volume":"29","author":"Wong","year":"2020","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib30","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.cels.2015.12.004","article-title":"The Molecular Signatures Database (MSigDB) hallmark gene set collection","volume":"1","author":"Liberzon","year":"2015","journal-title":"Cell Syst."},{"key":"10.1016\/j.isci.2024.109947_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.650874","article-title":"Investigating Transcriptional Dynamics Changes and Time-Dependent Marker Gene Expression in the Early Period After Skeletal Muscle Injury in Rats","volume":"12","author":"Ren","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib32","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/hmg\/ddad175","article-title":"FSHD muscle shows perturbation in fibroadipogenic progenitor cells, mitochondrial function and alternative splicing independently of inflammation","volume":"33","author":"Engquist","year":"2024","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2002829","article-title":"Microtubules underlie dysfunction in duchenne muscular dystrophy","volume":"5","author":"Khairallah","year":"2012","journal-title":"Sci. Signal."},{"key":"10.1016\/j.isci.2024.109947_bib34","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/hmg\/ddy432","article-title":"Transcriptome alterations in myotonic dystrophy skeletal muscle and heart","volume":"28","author":"Wang","year":"2019","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.isci.2024.109947_bib35","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0092-8674(00)00066-0","article-title":"Pax7 is required for the specification of myogenic satellite cells","volume":"102","author":"Seale","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.109947_bib36","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1083\/jcb.151.6.1221","article-title":"Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells","volume":"151","author":"Beauchamp","year":"2000","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.isci.2024.109947_bib37","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.celrep.2015.01.045","article-title":"Muscle stem cell fate is controlled by the cell-polarity protein Scrib","volume":"10","author":"Ono","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2024.109947_bib38","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0092-8674(89)90583-7","article-title":"Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD","volume":"56","author":"Wright","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.109947_bib39","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1101\/gad.3.5.628","article-title":"A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program","volume":"3","author":"Edmondson","year":"1989","journal-title":"Genes Dev."},{"key":"10.1016\/j.isci.2024.109947_bib40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nature12343","article-title":"Myomaker is a membrane activator of myoblast fusion and muscle formation","volume":"499","author":"Millay","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.isci.2024.109947_bib41","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s13395-015-0046-6","article-title":"Developmental myosins: expression patterns and functional significance","volume":"5","author":"Schiaffino","year":"2015","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.isci.2024.109947_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2021.101304","article-title":"Insulin action at a molecular level\u00a0\u2013 100 years of progress","volume":"52","author":"White","year":"2021","journal-title":"Mol. Metab."},{"key":"10.1016\/j.isci.2024.109947_bib43","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/372546a0","article-title":"Nitric oxide in skeletal muscle","volume":"372","author":"Kobzik","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.isci.2024.109947_bib44","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.51576","article-title":"Functionally heterogeneous human satellite cells identified by single cell RNA sequencing","volume":"9","author":"Barruet","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.isci.2024.109947_bib45","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13036-017-0093-0","article-title":"Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure","volume":"12","author":"Fu","year":"2018","journal-title":"J.\u00a0Biol. Eng."},{"key":"10.1016\/j.isci.2024.109947_bib46","doi-asserted-by":"crossref","first-page":"378","DOI":"10.2174\/1381612820666140826114744","article-title":"Emerging biology of PDE10A","volume":"21","author":"Wilson","year":"2015","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.isci.2024.109947_bib47","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ydbio.2004.07.034","article-title":"Muscle satellite cell-specific genes identified by genetic profiling of MyoD-deficient myogenic cell","volume":"275","author":"Seale","year":"2004","journal-title":"Dev. Biol."},{"key":"10.1016\/j.isci.2024.109947_bib48","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00441-010-0976-6","article-title":"Elevated satellite cell number in Duchenne muscular dystrophy","volume":"340","author":"Kottlors","year":"2010","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.isci.2024.109947_bib49","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/his.12231","article-title":"Fibre type-specific satellite cell content in two models of muscle disease","volume":"63","author":"Bankole","year":"2013","journal-title":"Histopathology"},{"key":"10.1016\/j.isci.2024.109947_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150818","article-title":"Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies","volume":"11","author":"Janghra","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2024.109947_bib51","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s40478-020-00918-5","article-title":"A high-throughput digital script for multiplexed immunofluorescent analysis and quantification of sarcolemmal and sarcomeric proteins in muscular dystrophies","volume":"8","author":"Scaglioni","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.isci.2024.109947_bib52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0960-8966(99)00093-0","article-title":"Shorter telomeres in dystrophic muscle consistent with extensive regeneration in young children","volume":"10","author":"Decary","year":"2000","journal-title":"Neuromuscul. Disord."},{"key":"10.1016\/j.isci.2024.109947_bib53","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/j.1365-2990.2009.01014.x","article-title":"Satellite cell dysfunction contributes to the progressive muscle atrophy in myotonic dystrophy type 1","volume":"35","author":"Thornell","year":"2009","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.isci.2024.109947_bib54","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3389\/fneur.2018.00368","article-title":"Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy","volume":"9","author":"Andre","year":"2018","journal-title":"Front. Neurol."},{"key":"10.1016\/j.isci.2024.109947_bib55","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3233\/JND-150077","article-title":"Immunohistochemical Characterization of Facioscapulohumeral Muscular Dystrophy Muscle Biopsies","volume":"2","author":"Statland","year":"2015","journal-title":"J.\u00a0Neuromuscul. Dis."},{"key":"10.1016\/j.isci.2024.109947_bib56","doi-asserted-by":"crossref","first-page":"3","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt Removes Adapter Sequences from High-Throughput Sequencing Reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet J."},{"key":"10.1016\/j.isci.2024.109947_bib57","author":"Andrews"},{"key":"10.1016\/j.isci.2024.109947_bib58","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1093\/bioinformatics\/btw354","article-title":"MultiQC: summarize analysis results for multiple tools and samples in a single report","volume":"32","author":"Ewels","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.isci.2024.109947_bib59","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nmeth.4197","article-title":"Salmon provides fast and bias-aware quantification of transcript expression","volume":"14","author":"Patro","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2024.109947_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1007664","article-title":"Tximeta: Reference sequence checksums for provenance identification in RNA-seq","volume":"16","author":"Love","year":"2020","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.isci.2024.109947_bib61","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.isci.2024.109947_bib62","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1471-2105-12-77","article-title":"pROC: an open-source package for R and S+ to analyze and compare ROC curves","volume":"12","author":"Robin","year":"2011","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.isci.2024.109947_bib63","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224011696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224011696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:22:59Z","timestamp":1782537779000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004224011696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":63,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S2589004224011696"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2024.109947","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptomic gene signatures measure satellite cell activity in muscular dystrophies","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2024.109947","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"109947"}}