{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T01:18:00Z","timestamp":1793755080773,"version":"4.6.1"},"reference-count":61,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008065","name":"Georgia Research Alliance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007699","name":"The University of Georgia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007699","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.isci.2024.110349","type":"journal-article","created":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T22:45:17Z","timestamp":1719096317000},"page":"110349","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["All hands on Dec: Treating cryptococcosis with dectin decorated liposomes loaded with antifungals"],"prefix":"10.1016","volume":"27","author":[{"given":"Tuyetnhu","family":"Pham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Ambati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Meagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3390-8387","authenticated-orcid":false,"given":"Xiaorong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2024.110349_bib1","doi-asserted-by":"crossref","first-page":"4829","DOI":"10.1128\/IAI.71.9.4829-4830.2003","article-title":"Updated view of Cryptococcus neoformans mating type and virulence","volume":"71","author":"Mitchell","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.isci.2024.110349_bib2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1078\/1438-4221-00216","article-title":"The role of mating type and morphology in Cryptococcus neoformans pathogenesis","volume":"292","author":"Wickes","year":"2002","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.isci.2024.110349_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1128\/MMBR.00045-10","article-title":"Regulatory circuitry governing fungal development, drug resistance, and disease","volume":"75","author":"Shapiro","year":"2011","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.isci.2024.110349_bib4","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1567-1364.2006.00056.x","article-title":"The pursuit of cryptococcal pathogenesis: heterologous hosts and the study of cryptococcal host-pathogen interactions","volume":"6","author":"London","year":"2006","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.isci.2024.110349_bib5","article-title":"Meningitis Caused by Cryptococcus neoformans in an Apparently Immunocompetent Patient","volume":"10","author":"Shokouhi","year":"2022","journal-title":"J.\u00a0Investig. Med. High Impact Case Rep."},{"key":"10.1016\/j.isci.2024.110349_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002765","article-title":"The link between morphotype transition and virulence in Cryptococcus neoformans","volume":"8","author":"Wang","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.isci.2024.110349_bib7","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s00408-011-9362-8","article-title":"Retrospective analysis of 76 immunocompetent patients with primary pulmonary cryptococcosis","volume":"190","author":"Ye","year":"2012","journal-title":"Lung"},{"key":"10.1016\/j.isci.2024.110349_bib8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/mmy\/myy086","article-title":"Pulmonary cryptococcosis: A review of pathobiology and clinical aspects","volume":"57","author":"Setianingrum","year":"2019","journal-title":"Med. Mycol."},{"key":"10.1016\/j.isci.2024.110349_bib9","doi-asserted-by":"crossref","DOI":"10.1177\/1179555717722962","article-title":"Pulmonary Cryptococcosis Presenting With Lung Mass: Report of 7 Cases and Review of Literature","volume":"10","author":"Kanjanapradit","year":"2017","journal-title":"Clin. Med. Insights Pathol."},{"key":"10.1016\/j.isci.2024.110349_bib10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1378\/chest.115.3.734","article-title":"Pulmonary cryptococcosis in patients without HIV infection","volume":"115","author":"Aberg","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.isci.2024.110349_bib11","doi-asserted-by":"crossref","first-page":"E70","DOI":"10.25011\/cim.v32i1.5090","article-title":"Pulmonary cryptococcosis in non-AIDS patients","volume":"32","author":"Wu","year":"2009","journal-title":"Clin. Invest. Med."},{"key":"10.1016\/j.isci.2024.110349_bib12","first-page":"236","article-title":"Primary pulmonary cryptococcosis","volume":"94","author":"Campbell","year":"1966","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib13","article-title":"Cryptococcal Meningitis in an Apparent Immunocompetent Patient","volume":"7","author":"Poley","year":"2019","journal-title":"J.\u00a0Investig. Med. High Impact Case Rep."},{"key":"10.1016\/j.isci.2024.110349_bib14","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","article-title":"Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis","volume":"17","author":"Rajasingham","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib15","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1080\/1040841X.2020.1869178","article-title":"Cryptococcus neoformans-astrocyte interactions: effect on fungal blood brain barrier disruption, brain invasion, and meningitis progression","volume":"47","author":"Woo","year":"2021","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.isci.2024.110349_bib16","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3201\/eid1405.071312","article-title":"Cryptococcus neoformans strains and infection in apparently immunocompetent patients, China","volume":"14","author":"Chen","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib17","doi-asserted-by":"crossref","first-page":"4922","DOI":"10.1128\/IAI.73.8.4922-4933.2005","article-title":"Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection","volume":"73","author":"Nielsen","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.isci.2024.110349_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-009129","article-title":"Cryptococcal sternal osteomyelitis in a healthy woman: a review of Cryptococcus neoformans","volume":"2013","author":"Jain","year":"2013","journal-title":"BMJ Case Rep."},{"key":"10.1016\/j.isci.2024.110349_bib19","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1439-0507.2004.00963.x","article-title":"Cryptococcal meningitis in two apparently immunocompetent Maltese patients","volume":"47","author":"Zahra","year":"2004","journal-title":"Mycoses"},{"key":"10.1016\/j.isci.2024.110349_bib20","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/S0272-6386(12)80683-4","article-title":"Cryptococcal infection of a prosthetic dialysis fistula","volume":"24","author":"Braun","year":"1994","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.isci.2024.110349_bib21","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1128\/IAI.00259-13","article-title":"Congenic strains of the filamentous form of Cryptococcus neoformans for studies of fungal morphogenesis and virulence","volume":"81","author":"Zhai","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.isci.2024.110349_bib22","first-page":"4437","article-title":"Comparative study of primary pulmonary cryptococcosis with multiple nodules or masses by CT and pathology","volume":"16","author":"Wang","year":"2018","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.isci.2024.110349_bib23","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1056\/NEJMoa1710922","article-title":"Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa","volume":"378","author":"Molloy","year":"2018","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.isci.2024.110349_bib24","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1016\/S1473-3099(22)00499-6","article-title":"The global burden of HIV-associated cryptococcal infection in adults in 2020: a modelling analysis","volume":"22","author":"Rajasingham","year":"2022","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib25","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1056\/NEJMoa2111904","article-title":"Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis","volume":"386","author":"Jarvis","year":"2022","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.isci.2024.110349_bib26","series-title":"Supplement to the 2016 Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection","article-title":"Guidelines for The Diagnosis, Prevention and Management of Cryptococcal Disease in HIV-Infected Adults, Adolescents and Children","year":"2018"},{"key":"10.1016\/j.isci.2024.110349_bib27","series-title":"Amphotericin B","author":"Noor","year":"2023"},{"key":"10.1016\/j.isci.2024.110349_bib28","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s40265-016-0538-7","article-title":"Liposomal Amphotericin B (AmBisome(\u00ae)): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions","volume":"76","author":"Stone","year":"2016","journal-title":"Drugs"},{"key":"10.1016\/j.isci.2024.110349_bib29","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/08982104.2017.1327543","article-title":"Tissue pharmacokinetics and pharmacodynamics of AmBisome\u00ae (L-AmBis) in uninfected and infected animals and their effects on dosing regimens","volume":"27","author":"Adler-Moore","year":"2017","journal-title":"J.\u00a0Liposome Res."},{"key":"10.1016\/j.isci.2024.110349_bib30","first-page":"S3","article-title":"AmBisome targeting to fungal infections","volume":"14","author":"Adler-Moore","year":"1994","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.isci.2024.110349_bib31","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1086\/649858","article-title":"Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america","volume":"50","author":"Perfect","year":"2010","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib32","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/cid\/ciy515","article-title":"Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus-associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial","volume":"68","author":"Jarvis","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2023.114776","article-title":"DectiSomes: C-type lectin receptor-targeted liposomes as pan-antifungal drugs","volume":"196","author":"Meagher","year":"2023","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.isci.2024.110349_bib34","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.coi.2009.01.003","article-title":"Pattern recognition: recent insights from Dectin-1","volume":"21","author":"Reid","year":"2009","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.isci.2024.110349_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0220867","article-title":"The pattern recognition receptors dectin-2, mincle, and FcR\u03b3 impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species","volume":"14","author":"Haider","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2024.110349_bib36","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.molimm.2015.07.002","article-title":"Murine pattern recognition receptor dectin-1 is essential in the development of experimental autoimmune uveoretinitis","volume":"67","author":"Stoppelkamp","year":"2015","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.isci.2024.110349_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009699","article-title":"Aiming for a bull's-eye: Targeting antifungals to fungi with dectin-decorated liposomes","volume":"17","author":"Meagher","year":"2021","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.isci.2024.110349_bib38","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/B978-0-12-387664-5.00003-0","article-title":"The control of adaptive immune responses by the innate immune system","volume":"109","author":"Schenten","year":"2011","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.isci.2024.110349_bib39","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.3389\/fmicb.2019.02993","article-title":"The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species","volume":"10","author":"Garcia-Rubio","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.isci.2024.110349_bib40","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.immuni.2013.05.017","article-title":"C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection","volume":"39","author":"Zhu","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.isci.2024.110349_bib41","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01467-21","article-title":"DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis","volume":"66","author":"Ambati","year":"2022","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.isci.2024.110349_bib42","article-title":"Dectin-2-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy","volume":"4","author":"Ambati","year":"2019","journal-title":"mSphere"},{"key":"10.1016\/j.isci.2024.110349_bib43","article-title":"Dectin-1-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy","volume":"4","author":"Ambati","year":"2019","journal-title":"mSphere"},{"key":"10.1016\/j.isci.2024.110349_bib44","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00030-21","article-title":"Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis","volume":"12","author":"Ambati","year":"2021","journal-title":"mBio"},{"key":"10.1016\/j.isci.2024.110349_bib45","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1128\/JCM.03177-13","article-title":"Multilocus sequence typing of serially collected isolates of Cryptococcus from HIV-infected patients in South Africa","volume":"52","author":"Van Wyk","year":"2014","journal-title":"J.\u00a0Clin. Microbiol."},{"key":"10.1016\/j.isci.2024.110349_bib46","first-page":"438","article-title":"Clinical and radiologic manifestations of pulmonary cryptococcosis in immunocompetent patients and their outcomes after treatment","volume":"19","author":"Suwatanapongched","year":"2013","journal-title":"Diagn. Interv. Radiol."},{"key":"10.1016\/j.isci.2024.110349_bib47","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1128\/AAC.26.4.446","article-title":"Comparative pharmacokinetics of Sch 28191 and amphotericin B in mice, rats, dogs, and cynomolgus monkeys","volume":"26","author":"Kim","year":"1984","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.isci.2024.110349_bib48","doi-asserted-by":"crossref","first-page":"905","DOI":"10.2147\/IJN.S17503","article-title":"Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice","volume":"6","author":"Xu","year":"2011","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.isci.2024.110349_bib49","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3109\/13693780903208249","article-title":"Differences in tissue drug concentrations following intravenous versus intraperitoneal treatment with amphotericin B deoxycholate or liposomal amphotericin B","volume":"48","author":"Chang","year":"2010","journal-title":"Med. Mycol."},{"key":"10.1016\/j.isci.2024.110349_bib50","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.82563","article-title":"The RAM signaling pathway links morphology, thermotolerance, and CO(2) tolerance in the global fungal pathogen Cryptococcus neoformans","volume":"11","author":"Chadwick","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.isci.2024.110349_bib51","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/jac\/28.suppl_B.49","article-title":"Pharmacology and toxicology of a liposomal formulation of amphotericin B (AmBisome) in rodents","volume":"28","author":"Proffitt","year":"1991","journal-title":"J.\u00a0Antimicrob. Chemother."},{"key":"10.1016\/j.isci.2024.110349_bib52","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1128\/AAC.01488-07","article-title":"Comparison of lipid amphotericin B preparations in treating murine zygomycosis","volume":"52","author":"Ibrahim","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.isci.2024.110349_bib53","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1023\/A:1018997730462","article-title":"Safety and toxicokinetics of intravenous liposomal amphotericin B (AmBisome) in beagle dogs","volume":"16","author":"Bekersky","year":"1999","journal-title":"Pharm. Res. (N. Y.)"},{"key":"10.1016\/j.isci.2024.110349_bib54","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1002\/jps.20801","article-title":"Assessing the antifungal activity, pharmacokinetics, and tissue distribution of amphotericin B following the administration of Abelcet and AmBisome in combination with caspofungin to rats infected with Aspergillus fumigatus","volume":"96","author":"Wasan","year":"2007","journal-title":"J.\u00a0Pharm. Sci."},{"key":"10.1016\/j.isci.2024.110349_bib55","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1086\/315643","article-title":"Comparative efficacy and distribution of lipid formulations of amphotericin B in experimental Candida albicans infection of the central nervous system","volume":"182","author":"Groll","year":"2000","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.isci.2024.110349_bib56","first-page":"297","article-title":"Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential","volume":"1","author":"Immordino","year":"2006","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.isci.2024.110349_bib57","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/mmi.15174","article-title":"Dectin-3-targeted antifungal liposomes efficiently bind and kill diverse fungal pathogens","volume":"120","author":"Choudhury","year":"2023","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.isci.2024.110349_bib58","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02785-21","article-title":"Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology","volume":"13","author":"Lin","year":"2022","journal-title":"mBio"},{"key":"10.1016\/j.isci.2024.110349_bib59","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01433-15","article-title":"Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants","volume":"6","author":"Zhai","year":"2015","journal-title":"mBio"},{"key":"10.1016\/j.isci.2024.110349_bib60","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1128\/AAC.00212-12","article-title":"The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections","volume":"56","author":"Zhai","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.isci.2024.110349_bib61","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/j.cub.2020.01.081","article-title":"Activation of Meiotic Genes Mediates Ploidy Reduction during Cryptococcal Infection","volume":"30","author":"Zhao","year":"2020","journal-title":"Curr. Biol."}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224015748?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224015748?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T04:55:24Z","timestamp":1747457724000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004224015748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":61,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S2589004224015748"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2024.110349","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"All hands on Dec: Treating cryptococcosis with dectin decorated liposomes loaded with antifungals","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2024.110349","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110349"}}