{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:07:10Z","timestamp":1785535630403,"version":"3.56.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["BR 1744\/20-1"],"award-info":[{"award-number":["BR 1744\/20-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010127","name":"J\u00fcrgen Manchot Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010127","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009139","name":"DZIF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009139","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.isci.2024.111265","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T03:59:04Z","timestamp":1730260744000},"page":"111265","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Distinct brain and lung endothelial miRNA\/mRNA profiles after exposure to Plasmodium falciparum-infected red blood cells"],"prefix":"10.1016","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9423-7145","authenticated-orcid":false,"given":"Nahla Galal","family":"Metwally","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria del Pilar Martinez","family":"Tauler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanifeh","family":"Torabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Allweier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryeva","family":"Bessemoulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Bouws","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Alshikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milad","family":"Temori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tabea","family":"Schell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximillian","family":"Rakotonirinalalao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Honecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"H\u00f6hn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Heine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Bruchhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2024.111265_bib1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s40471-021-00266-5","article-title":"Antimalarial Drug Resistance and Implications for the WHO Global Technical Strategy","volume":"8","author":"Ippolito","year":"2021","journal-title":"Curr. Epidemiol. Rep."},{"key":"10.1016\/j.isci.2024.111265_bib2","first-page":"477","article-title":"Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs): Fears of widespread drug resistance]","volume":"200","author":"Benoit-Vical","year":"2016","journal-title":"Bull. Acad. Natl. Med."},{"key":"10.1016\/j.isci.2024.111265_bib3","series-title":"WHO Malaria report","year":"2023"},{"key":"10.1016\/j.isci.2024.111265_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2020.618454","article-title":"From Genes to Transcripts, a Tightly Regulated Journey in Plasmodium","volume":"10","author":"Hollin","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.isci.2024.111265_bib5","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1146\/annurev-pathmechdis-012419-032640","article-title":"New Insights into Malaria Pathogenesis","volume":"15","author":"Moxon","year":"2020","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.isci.2024.111265_bib6","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3007432","article-title":"Piecing together the puzzle of severe malaria","volume":"5","author":"Cunnington","year":"2013","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.isci.2024.111265_bib7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/1475-2875-12-191","article-title":"A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria","volume":"12","author":"Milner","year":"2013","journal-title":"Malar. J."},{"key":"10.1016\/j.isci.2024.111265_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/bs.apar.2015.02.004","article-title":"PfEMP1 - A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis","volume":"88","author":"Hviid","year":"2015","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.isci.2024.111265_bib9","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.biocel.2008.12.012","article-title":"PfEMP1: an antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum","volume":"41","author":"Pasternak","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.isci.2024.111265_bib10","doi-asserted-by":"crossref","first-page":"4548","DOI":"10.1038\/s41598-020-61388-2","article-title":"Adhesion between P. falciparum infected erythrocytes and human endothelial receptors follows alternative binding dynamics under flow and febrile conditions","volume":"10","author":"Lubiana","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.111265_bib11","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/infdis\/jis681","article-title":"Microvascular dysfunction in severe Plasmodium falciparum Malaria","volume":"207","author":"Cunnington","year":"2013","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.isci.2024.111265_bib12","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1111\/j.1365-2141.2011.08755.x","article-title":"Malaria: modification of the red blood cell and consequences in the human host","volume":"154","author":"Moxon","year":"2011","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.isci.2024.111265_bib13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/nm986","article-title":"Differentiating the pathologies of cerebral malaria by postmortem parasite counts","volume":"10","author":"Taylor","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.isci.2024.111265_bib14","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.3390\/ijerph19042395","article-title":"MiRNA: Biological Regulator in Host-Parasite Interaction during Malaria Infection","volume":"19","author":"Kataria","year":"2022","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.isci.2024.111265_bib15","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1101\/gr.082701.108","article-title":"Most mammalian mRNAs are conserved targets of microRNAs","volume":"19","author":"Friedman","year":"2009","journal-title":"Genome Res."},{"key":"10.1016\/j.isci.2024.111265_bib16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.3389\/fgene.2018.00435","article-title":"Target RNAs Strike Back on MicroRNAs","volume":"9","author":"Fuchs Wightman","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.isci.2024.111265_bib17","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/nar\/gkab1256","article-title":"Reexamining assumptions about miRNA-guided gene silencing","volume":"50","author":"Kilikevicius","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.isci.2024.111265_bib18","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0092-8674(93)90529-Y","article-title":"The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14","volume":"75","author":"Lee","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.isci.2024.111265_bib19","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3390\/cells9020276","article-title":"miRNAs as biomarkers in disease: Latest findings regarding their role in diagnosis and prognosis","volume":"9","author":"Condrat","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.isci.2024.111265_bib20","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.3390\/cells8111465","article-title":"The Non-Canonical Aspects of MicroRNAs: Many Roads to Gene Regulation","volume":"8","author":"Stavast","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.isci.2024.111265_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/wrna.1627","article-title":"microRNA strand selection: Unwinding the rules","volume":"12","author":"Medley","year":"2021","journal-title":"Wiley Interdiscip. Rev. RNA"},{"key":"10.1016\/j.isci.2024.111265_bib22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/wrna.121","article-title":"Posttranscriptional upregulation by microRNAs","volume":"3","author":"Vasudevan","year":"2012","journal-title":"Wiley Interdiscip. Rev. RNA"},{"key":"10.1016\/j.isci.2024.111265_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.668648","article-title":"The MicroRNA Family Gets Wider: The IsomiRs Classification and Role","volume":"9","author":"Tomasello","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib24","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/nmeth0709-474","article-title":"Limitations and possibilities of small RNA digital gene expression profiling","volume":"6","author":"Linsen","year":"2009","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2024.111265_bib25","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1101\/gr.118059.110","article-title":"Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity","volume":"21","author":"Wyman","year":"2011","journal-title":"Genome Res."},{"key":"10.1016\/j.isci.2024.111265_bib26","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-15388-4","article-title":"Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes","volume":"7","author":"Haseeb","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.111265_bib27","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1749-6632.1987.tb33025.x","article-title":"Vascular endothelium: nature's blood-compatible container","volume":"516","author":"Gimbrone","year":"1987","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.isci.2024.111265_bib28","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.3390\/ijms20184411","article-title":"Vascular Endothelial Cell Biology: An Update","volume":"20","author":"Kr\u00fcger-Genge","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2024.111265_bib29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/s41569-022-00770-1","article-title":"Red-Horse, K. Vascular endothelial cell development and diversity","volume":"20","author":"Trimm","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.isci.2024.111265_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceb.2023.102232","article-title":"Integration of Chemo-mechanical signaling in response to fluid shear stress by the endothelium","volume":"85","author":"Dominguez","year":"2023","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.isci.2024.111265_bib31","doi-asserted-by":"crossref","first-page":"861","DOI":"10.3389\/fphys.2020.00861","article-title":"Fluid Shear Stress Sensing by the Endothelial Layer","volume":"11","author":"Roux","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib32","article-title":"Biological Properties of Extracellular Vesicles and Their Physiological Functions","volume":"4","author":"Y\u00e1\u00f1ez-M\u00f3","year":"2015","journal-title":"J.\u00a0Extracell. Vesicles"},{"key":"10.1016\/j.isci.2024.111265_bib33","article-title":"Minimal Information for Studies of Extracellular Vesicles 2018 (MISEV2018): A Position Statement of the International Society for Extracellular Vesicles and Update of the MISEV2014 Guidelines","volume":"7","author":"Th\u00e9ry","year":"2018","journal-title":"J.\u00a0Extracell. Vesicles"},{"key":"10.1016\/j.isci.2024.111265_bib34","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.51413","article-title":"Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation","volume":"9","author":"Jambusaria","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.isci.2024.111265_bib35","article-title":"Plasmodium falciparum infection reshapes the human microRNA profiles of red blood cells and their extracellular vesicles","volume":"26","author":"Wu","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.isci.2024.111265_bib36","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.3390\/ijms18061153","article-title":"The Methods of Choice for Extracellular Vesicles (EVs) Characterization","volume":"18","author":"Szatanek","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2024.111265_bib37","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s002329900565","article-title":"Fluid flow modulates calcium entry and activates membrane currents in cultured human aortic endothelial cells","volume":"171","author":"Jow","year":"1999","journal-title":"J.\u00a0Membr. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib38","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/325811a0","article-title":"Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?","volume":"325","author":"Lansman","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.isci.2024.111265_bib39","doi-asserted-by":"crossref","first-page":"C238","DOI":"10.1152\/ajpcell.1999.276.1.C238","article-title":"Mechanical stress-induced Ca2+ entry and Cl\u2212 current in cultured human aortic endothelial cells","volume":"276","author":"Nakao","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib40","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1113\/jphysiol.1992.sp019432","article-title":"Shear stress-induced calcium transients in endothelial cells from human umbilical cord veins","volume":"458","author":"Schwarz","year":"1992","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib41","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s12551-021-00839-0","article-title":"Mechanosensitive pathways are regulated by mechanosensitive miRNA clusters in endothelial cells","volume":"13","author":"Herault","year":"2021","journal-title":"Biophys. Rev."},{"key":"10.1016\/j.isci.2024.111265_bib42","doi-asserted-by":"crossref","first-page":"7827","DOI":"10.1002\/jcp.29436","article-title":"Epigenetic response of endothelial cells to different wall shear stress magnitudes: A report of new mechano-miRNAs","volume":"235","author":"Rashad","year":"2020","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib43","doi-asserted-by":"crossref","first-page":"459","DOI":"10.3390\/jcm11020459","article-title":"Flow-Responsive Noncoding RNAs in the Vascular System: Basic Mechanisms for the Clinician","volume":"11","author":"De Rosa","year":"2022","journal-title":"J.\u00a0Clin. Med."},{"key":"10.1016\/j.isci.2024.111265_bib44","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/BF00374230","article-title":"Shear stress induced membrane currents and calcium transients in human vascular endothelial cells","volume":"421","author":"Schwarz","year":"1992","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.isci.2024.111265_bib45","first-page":"H1745","article-title":"Mechanical perturbation of cultured human endothelial cells causes rapid increases of intracellular calcium","volume":"264","author":"Sigurdson","year":"1993","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib46","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1152\/physiol.00007.2016","article-title":"Ion Channels in Endothelial Responses to Fluid Shear Stress","volume":"31","author":"Gerhold","year":"2016","journal-title":"Physiology"},{"key":"10.1016\/j.isci.2024.111265_bib47","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1152\/physiolgenomics.00102.2002","article-title":"Gene expression profile of human endothelial cells exposed to sustained fluid shear stress","volume":"12","author":"Wasserman","year":"2002","journal-title":"Physiol. Genom."},{"key":"10.1016\/j.isci.2024.111265_bib48","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/jcp.29844","article-title":"Low shear stress regulates vascular endothelial cell pyroptosis through miR-181b-5p\/STAT-3 axis","volume":"236","author":"Xu","year":"2021","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.isci.2024.111265_bib49","doi-asserted-by":"crossref","first-page":"5062","DOI":"10.1111\/jcmm.13790","article-title":"The interplay of Lnc RNA ANRIL and miR-181b on the inflammation-relevant coronary artery disease through mediating NF-\u03baB signalling pathway","volume":"22","author":"Guo","year":"2018","journal-title":"J.\u00a0Cell Mol. Med."},{"key":"10.1016\/j.isci.2024.111265_bib50","doi-asserted-by":"crossref","first-page":"5945","DOI":"10.1074\/jbc.M807205200","article-title":"Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38{beta} MAPK-NF-{kappa}B pathway","volume":"284","author":"Shaik","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.isci.2024.111265_bib51","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12936-018-2330-5","article-title":"Differential plasma microvesicle and brain profiles of microRNA in experimental cerebral malaria","volume":"17","author":"Cohen","year":"2018","journal-title":"Malar. J."},{"key":"10.1016\/j.isci.2024.111265_bib52","doi-asserted-by":"crossref","first-page":"647","DOI":"10.3389\/fbioe.2020.00647","article-title":"Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1","volume":"8","author":"Yang","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.isci.2024.111265_bib53","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1084\/jem.177.5.1277","article-title":"Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55","volume":"177","author":"Mackay","year":"1993","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.isci.2024.111265_bib54","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1161\/ATVBAHA.120.314330","article-title":"Vascular Endothelial Cells and Innate Immunity","volume":"40","author":"Shao","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib55","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1086\/512083","article-title":"Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers","volume":"195","author":"Tripathi","year":"2007","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.isci.2024.111265_bib56","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-29721-y","article-title":"Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-\u03b2 signalling pathways","volume":"8","author":"Martin-Alonso","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.111265_bib57","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s12967-018-1646-9","article-title":"Screening and identification of potential novel biomarker for diagnosis of complicated Plasmodium vivax malaria","volume":"16","author":"Kaur","year":"2018","journal-title":"J.\u00a0Transl. Med."},{"key":"10.1016\/j.isci.2024.111265_bib58","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.exppara.2015.04.013","article-title":"Downregulation of plasma miR-451 and miR-16 in Plasmodium vivax infection","volume":"155","author":"Chamnanchanunt","year":"2015","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.isci.2024.111265_bib59","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1128\/IAI.01136-10","article-title":"Differential microRNA expression in experimental cerebral and noncerebral malaria","volume":"79","author":"El-Assaad","year":"2011","journal-title":"Infect. Immun."},{"key":"10.1016\/j.isci.2024.111265_bib60","first-page":"3","article-title":"Routes and mechanisms of extracellular vesicle uptake","volume":"3","author":"Mulcahy","year":"2014","journal-title":"J.\u00a0Extracell. Vesicles"},{"key":"10.1016\/j.isci.2024.111265_bib61","doi-asserted-by":"crossref","first-page":"4444","DOI":"10.1021\/acsnano.9b10033","article-title":"Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes","volume":"14","author":"Joshi","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.isci.2024.111265_bib62","doi-asserted-by":"crossref","first-page":"5791","DOI":"10.3390\/ijms24065791","article-title":"Intracellular Membrane Transport in Vascular Endothelial Cells","volume":"24","author":"Mironov","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2024.111265_bib63","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1146\/annurev.cellbio.12.1.575","article-title":"Endocytosis and molecular sorting","volume":"12","author":"Mellman","year":"1996","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib64","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm3151","article-title":"Molecular mechanism and physiological functions of clathrin-mediated endocytosis","volume":"12","author":"McMahon","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.isci.2024.111265_bib65","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1378\/chest.97.5.1190","article-title":"Pulmonary edema in severe falciparum malaria. Hemodynamic study and clinicophysiologic correlation","volume":"97","author":"Charoenpan","year":"1990","journal-title":"Chest"},{"key":"10.1016\/j.isci.2024.111265_bib66","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202101161R","article-title":"The role of the electron transport chain in immunity","volume":"35","author":"Yin","year":"2021","journal-title":"Faseb. J."},{"key":"10.1016\/j.isci.2024.111265_bib67","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/s41590-022-01185-3","article-title":"Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation","volume":"23","author":"Billingham","year":"2022","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.isci.2024.111265_bib68","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222111338","article-title":"Mitochondria as a Cellular Hub in Infection and Inflammation","volume":"22","author":"Andrieux","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2024.111265_bib69","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.devcel.2008.07.008","article-title":"miR126 regulates angiogenic signaling and vascular integrity","volume":"15","author":"Fish","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1016\/j.isci.2024.111265_bib70","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1161\/ATVBAHA.119.313800","article-title":"MicroRNA-126-3p inhibits angiogenic function of human lung microvascular endothelial cells via LAT1 (L-type amino acid transporter 1)-mediated mTOR (mammalian target of rapamycin) signaling","volume":"40","author":"Cao","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib71","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1038\/s41598-017-04241-3","article-title":"Characterisation of Plasmodium falciparum populations selected on the human endothelial receptors P-selectin, E-selectin, CD9 and CD151","volume":"7","author":"Metwally","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2024.111265_bib72","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1645\/0022-3395(2005)091[0484:HMPICC]2.0.CO;2","article-title":"Human malaria parasites in continuous culture. 1976","volume":"91","author":"Trager","year":"2005","journal-title":"J.\u00a0Parasitol."},{"key":"10.1016\/j.isci.2024.111265_bib73","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/978-1-0716-1681-9_11","article-title":"Analysis of the Interaction Between Plasmodium falciparum-Infected Erythrocytes and Human Endothelial Cells Using a Laminar Flow System, Bioinformatic Tracking and Transcriptome Analysis","volume":"2369","author":"Wu","year":"2021","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.isci.2024.111265_bib74","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.chom.2013.04.009","article-title":"Malaria-infected erythrocytederived microvesicles mediate cellular communication within the parasite population and with the host immune system","volume":"13","author":"Mantel","year":"2013","journal-title":"Cell Host Microbe"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224024908?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004224024908?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T21:19:06Z","timestamp":1783372746000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004224024908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":74,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S2589004224024908"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2024.111265","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Distinct brain and lung endothelial miRNA\/mRNA profiles after exposure to Plasmodium falciparum-infected red blood cells","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2024.111265","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111265"}}