{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:24:43Z","timestamp":1786991083575,"version":"build-2736575974"},"reference-count":82,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R24\/U24ES929490"],"award-info":[{"award-number":["R24\/U24ES929490"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R01NR014800"],"award-info":[{"award-number":["R01NR014800"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["K01 NR017664-01"],"award-info":[{"award-number":["K01 NR017664-01"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007623","name":"School of Medicine, Emory University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007623","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008065","name":"Georgia Research Alliance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.isci.2025.113955","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:48:42Z","timestamp":1762390122000},"page":"113955","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Postpartum lipid dysregulation in African American women who experienced cardiometabolic complications of pregnancy"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2274-4284","authenticated-orcid":false,"given":"Kristal","family":"Maner-Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyun Liu","family":"Gulbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Ortlund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne L.","family":"Dunlop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Ferranti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2025.113955_bib1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/00001703-200312000-00002","article-title":"Pregnancy: a stress test for life","volume":"15","author":"Williams","year":"2003","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"10.1016\/j.isci.2025.113955_bib2","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.amjcard.2013.08.054","article-title":"Recognizing pregnancy-associated cardiovascular risk factors","volume":"113","author":"Wenger","year":"2014","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.isci.2025.113955_bib3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.whi.2023.08.001","article-title":"Social Determinant Pathways to Hypertensive Disorders of Pregnancy Among Nulliparous U.S. Women","volume":"34","author":"Keith","year":"2024","journal-title":"Womens Health Issues"},{"key":"10.1016\/j.isci.2025.113955_bib4","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1089\/jwh.2023.0560","article-title":"Racial and Socioeconomic Disparities in Preconception Health Risk Factors and Access to Care","volume":"33","author":"Rokicki","year":"2024","journal-title":"J Womens Health"},{"key":"10.1016\/j.isci.2025.113955_bib5","article-title":"Racial differences of incident diabetes postpartum in women with a history of gestational diabetes","volume":"33","author":"Yun Shen","year":"2019","journal-title":"J. Diabet. Comp."},{"key":"10.1016\/j.isci.2025.113955_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2024.101276","article-title":"Oxylipin profiling for clinical research: Current status and future perspectives","volume":"95","author":"Parchem","year":"2024","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.isci.2025.113955_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexmp.2024.104895","article-title":"Circulating perturbation of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) is associated to cardiac remodeling and NLRP3 inflammasome in cardiovascular patients with insulin resistance risk","volume":"137","author":"Vianello","year":"2024","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.isci.2025.113955_bib8","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.012729","article-title":"Racial Differences in Cardiovascular Biomarkers in the General Population","volume":"8","author":"Hackler","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.isci.2025.113955_bib9","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1056\/NEJMra1104901","article-title":"The Human Plasma Lipidome","volume":"365","author":"Quehenberger","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.isci.2025.113955_bib10","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.3390\/ijms23126786","article-title":"Lipidomic Approaches to Study HDL Metabolism in Patients with Central Obesity Diagnosed with Metabolic Syndrome","volume":"23","author":"Mocciaro","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2025.113955_bib11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12916-023-02740-x","article-title":"Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study","volume":"21","author":"Chen","year":"2023","journal-title":"BMC Med."},{"key":"10.1016\/j.isci.2025.113955_bib12","article-title":"Plasma lipidomics profile in pregnancy and gestational diabetes risk: a prospective study in a multiracial\/ethnic cohort","volume":"9","author":"Mohammad","year":"2021","journal-title":"BMJ Open Diabetes Research & Care"},{"key":"10.1016\/j.isci.2025.113955_bib13","article-title":"African American Women with Cardiometabolic Complications of Pregnancy Have Decreased Serum Abundance of Specialized Pro-Resolving Lipid Mediators and Endocannabinoids","volume":"15","author":"Maner-Smith KM","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.isci.2025.113955_bib14","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/s41556-024-01377-z","article-title":"A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility","volume":"26","author":"Morgan","year":"2024","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.isci.2025.113955_bib15","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1186\/s12884-017-1357-x","article-title":"Protocol for the Emory University African American Vaginal, Oral, and Gut Microbiome in Pregnancy Cohort Study","volume":"17","author":"Corwin","year":"2017","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.isci.2025.113955_bib16","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/JCN.0000000000000823","article-title":"A Call to Action: Cardiovascular-Related Maternal Mortality: Inequities in Black, Indigenous, and Persons of Color","volume":"36","author":"Ferranti","year":"2021","journal-title":"J. Cardiovasc. Nurs."},{"key":"10.1016\/j.isci.2025.113955_bib17","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/JCN.0000000000001020","article-title":"A Continued Call to Action: Cardiovascular-Related Maternal Mortality Inequities in Black, Indigenous, and Persons of Color; What Has Changed in the Last 2 Years?","volume":"38","author":"Ferranti","year":"2023","journal-title":"J. Cardiovasc. Nurs."},{"key":"10.1016\/j.isci.2025.113955_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/1515321","article-title":"Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study","volume":"2020","author":"Ferranti","year":"2020","journal-title":"J. Pregnancy"},{"key":"10.1016\/j.isci.2025.113955_bib19","doi-asserted-by":"crossref","first-page":"438","DOI":"10.3390\/healthcare11030438","article-title":"Listen to the Whispers before They Become Screams: Addressing Black Maternal Morbidity and Mortality in the United States","volume":"11","author":"Njoku","year":"2023","journal-title":"Healthcare (Basel)"},{"key":"10.1016\/j.isci.2025.113955_bib20","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1002\/oby.23517","article-title":"An Pan BMI and lipidomic biomarkers with risk of gestational diabetes in pregnant women","volume":"30","author":"Wang","year":"2022","journal-title":"Obesity"},{"key":"10.1016\/j.isci.2025.113955_bib21","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1756-0500-5-34","article-title":"Effect of maternal body mass index on pregnancy outcome and newborn weight","volume":"5","author":"Yazdani","year":"2012","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.isci.2025.113955_bib22","first-page":"5","article-title":"Association of Maternal Age and Blood Markers for Metabolic Disease in Newborns","volume":"14","author":"Yuhan","year":"2024","journal-title":"Metabolites"},{"key":"10.1016\/j.isci.2025.113955_bib23","first-page":"191","article-title":"Maternal Perinatal Outcomes Related to Advanced Maternal Age in Preeclampsia Pregnant Women","volume":"13","author":"Tyas","year":"2019","journal-title":"J. Family Reprod. Health"},{"key":"10.1016\/j.isci.2025.113955_bib24","doi-asserted-by":"crossref","first-page":"B25","DOI":"10.1016\/j.ajog.2022.07.022","article-title":"Pregnancy at age 35 years or older","volume":"228","author":"American College of Obstetricians and Gynecologists\u2019 Committee on Clinical Consensus-Obstetrics","year":"2023","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.isci.2025.113955_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2022.111898","article-title":"Identification of potential biomarkers and metabolic insights for gestational diabetes prevention: A review of evidence contrasting gestational diabetes versus weight loss studies that may direct future nutritional metabolomics studies","volume":"107","author":"Heath","year":"2023","journal-title":"Nutrition"},{"key":"10.1016\/j.isci.2025.113955_bib26","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.3389\/fphys.2018.01838","article-title":"Obesity and Preeclampsia: Common Pathophysiological Mechanisms","volume":"9","author":"Patricio Lopez-Jaramillo","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.isci.2025.113955_bib27","doi-asserted-by":"crossref","first-page":"3978","DOI":"10.1172\/JCI129186","article-title":"Metabolically healthy obesity: facts and fantasies","volume":"129","author":"Smith GI","year":"2019","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.isci.2025.113955_bib28","doi-asserted-by":"crossref","first-page":"e141","DOI":"10.1038\/nutd.2014.38","article-title":"Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults","volume":"4","author":"Hanamatsu","year":"2014","journal-title":"Nutr. Diabetes"},{"key":"10.1016\/j.isci.2025.113955_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241814015","article-title":"Circulating Sphingolipids in Insulin Resistance, Diabetes and Associated Complications","volume":"24","author":"Hammad","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2025.113955_bib30","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/jcmm.13984","article-title":"The relationship between phospholipids and insulin resistance: From clinical to experimental studies","volume":"23","author":"Chang","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.isci.2025.113955_bib31","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1093\/bioinformatics\/btx012","article-title":"Sparse network modeling and metscape-based visualization methods for the analysis of large-scale metabolomics data","volume":"33","author":"Basu","year":"2017","journal-title":"Bioinformatics"},{"key":"10.1016\/j.isci.2025.113955_bib32","first-page":"743","article-title":"Using MetaboAnalyst 5.0 for LC\u2013HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data","volume":"6","author":"Zhiqiang Pang","year":"2011","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.isci.2025.113955_bib33","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.3390\/ijms21031019","article-title":"Sphingolipid Signature of Human Feto-Placental Vasculature in Preeclampsia","volume":"21","author":"Ilaria Del Gaudio","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2025.113955_bib34","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.3390\/metabo13091026","article-title":"Effects of Pregnancy on Plasma Sphingolipids Using a Metabolomic and Quantitative Analysis Approach","volume":"13","author":"Luke","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.isci.2025.113955_bib35","article-title":"Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic b Cell Dysfunction","volume":"23","author":"Saifur","year":"2020","journal-title":"iScience"},{"key":"10.1016\/j.isci.2025.113955_bib36","first-page":"122","article-title":"Preeclampsia: a review of the role of prostaglandins","volume":"71","author":"Friedman","year":"1988","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.isci.2025.113955_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2022.101157","article-title":"Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions","volume":"86","author":"Monroig","year":"2022","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.isci.2025.113955_bib38","doi-asserted-by":"crossref","first-page":"3889","DOI":"10.1038\/s41598-017-04288-2","article-title":"Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish","volume":"7","author":"Angela Oboh","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2025.113955_bib39","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jacl.2022.02.005","article-title":"Hyperlipidemia and risk for preclampsia","volume":"16","author":"Indu","year":"2022","journal-title":"J. Clin. Lipidol."},{"key":"10.1016\/j.isci.2025.113955_bib40","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0002-9378(79)90469-1","article-title":"The hyperlipidemia of pregnancy in normal and complicated pregnancies","volume":"133","author":"Potter","year":"1979","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.isci.2025.113955_bib41","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1038\/s41598-018-37757-3","article-title":"Increased biosynthesis and accumulation of cholesterol in maternal plasma, but not amniotic fluid in pre-eclampsia","volume":"9","author":"Lee","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2025.113955_bib42","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1210\/clinem\/dgz119","article-title":"Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later","volume":"105","author":"Thor Ueland","year":"2020","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.isci.2025.113955_bib43","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0952-3278(03)00024-3","article-title":"Fatty acid composition of phospholipids and cholesteryl esters in maternal serum in the early puerperium","volume":"68","author":"De Vriese","year":"2003","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.isci.2025.113955_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11745-003-1023-y","article-title":"FA Composition of Cholesteryl Esters and Phospholipids in Maternal Plasma During Pregnancy and at Delivery and in Cord Plasma at Birth","volume":"38","author":"De Vriese","year":"2003","journal-title":"Lipids"},{"key":"10.1016\/j.isci.2025.113955_bib45","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3945\/an.114.007732","article-title":"Aukema Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs","volume":"6","author":"Melissa Gabbs","year":"2015","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.isci.2025.113955_bib46","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1038\/s41598-020-59120-1","article-title":"The endocannabinoid hydrolase FAAH is an allosteric enzyme","volume":"10","author":"Dainese","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2025.113955_bib47","article-title":"Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review","volume":"12","author":"Melissa","year":"2021","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.isci.2025.113955_bib48","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1054\/plef.2001.0358","article-title":"The fatty acid amide hydrolase (FAAH)","volume":"66","author":"Deutsch","year":"2002","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"10.1016\/j.isci.2025.113955_bib49","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1007\/s00380-014-0514-7","article-title":"Lipoprotein-associated phospholipase A2 is associated with postpartum hypertension in women with history of preeclampsia","volume":"30","author":"Zhou","year":"2015","journal-title":"Heart Vessel."},{"key":"10.1016\/j.isci.2025.113955_bib50","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/iub.337","article-title":"The Kennedy Pathway\u2014De Novo Synthesis of Phosphatidylethanolamine and Phosphatidylcholine","volume":"62","author":"Smith","year":"2010","journal-title":"IUBMB Life"},{"key":"10.1016\/j.isci.2025.113955_bib51","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.tips.2017.04.004","article-title":"Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance","volume":"38","author":"Petersen","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.isci.2025.113955_bib52","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/1471-0528.17297","article-title":"Maternal plasma diacylglycerols and triacylglycerols in the prediction of gestational diabetes mellitus","volume":"130","author":"Hou","year":"2023","journal-title":"BJOG"},{"key":"10.1016\/j.isci.2025.113955_bib53","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.bbalip.2012.01.009","article-title":"Lysophosphatidylinositol signalling: New wine from an old bottle","volume":"1821","author":"Pi\u00f1eiro","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib54","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.prostaglandins.2013.05.004","article-title":"The actions and metabolism of lysophosphatidylinositol, an endogenous agonist for GPR55","volume":"107","author":"Yamashita","year":"2013","journal-title":"Prostaglandins Other Lipid Mediat."},{"key":"10.1016\/j.isci.2025.113955_bib55","doi-asserted-by":"crossref","first-page":"281","DOI":"10.2337\/db11-0649","article-title":"The l-\u03b1-Lysophosphatidylinositol\/GPR55 System and Its Potential Role in Human Obesity","volume":"61","author":"Moreno-Navarrete","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.isci.2025.113955_bib56","article-title":"LIPEA: Lipid Pathway Enrichment Analysis","author":"Aldo Acevedo","year":"2018","journal-title":"bioRxiv"},{"key":"10.1016\/j.isci.2025.113955_bib57","doi-asserted-by":"crossref","first-page":"5728","DOI":"10.1038\/s41467-023-41462-9","article-title":"The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism","volume":"14","author":"Oh","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2025.113955_bib58","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/s41586-020-2732-8","article-title":"Plasticity of ether lipids promotes ferroptosis susceptibility and evasion","volume":"585","author":"Zou","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.isci.2025.113955_bib59","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nchembio.2238","article-title":"Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis","volume":"13","author":"Kagan","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.isci.2025.113955_bib60","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1083838","article-title":"Role of ferroptosis in pregnancy related diseases and its therapeutic potential","volume":"11","author":"Xu","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.isci.2025.113955_bib61","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/MED.0b013e328329233b","article-title":"Lecithin:Cholesterol Acyltransferase: From Biochemistry to Role in Cardiovascular Disease","volume":"16","author":"Rousset","year":"2009","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"key":"10.1016\/j.isci.2025.113955_bib62","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11883-011-0171-6","article-title":"Lecithin cholesterol acyltransferase: an anti- or pro-atherogenic factor?","volume":"13","author":"Rousset","year":"2011","journal-title":"Curr. Atheroscler. Rep."},{"key":"10.1016\/j.isci.2025.113955_bib63","article-title":"Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol","volume":"27","author":"Manthei KA","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.isci.2025.113955_bib64","doi-asserted-by":"crossref","first-page":"5029","DOI":"10.1021\/bi0600704","article-title":"Regulation of the activity and fatty acid specificity of lecithin-cholesterol acyltransferase by sphingomyelin, and its metabolites ceramide and ceramide phosphate","volume":"45","author":"Papasani","year":"2006","journal-title":"Biochemistry"},{"key":"10.1016\/j.isci.2025.113955_bib65","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0005-2760(97)00172-0","article-title":"Effect of the surface lipid composition of reconstituted LPA-I on apolipoprotein A-I structure and lecithin:cholesterol acyltransferase activity","volume":"1390","author":"Sparks","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib66","first-page":"716","article-title":"Sphingomyelin in High-Density Lipoproteins: Structural Role and Biological Function","volume":"14","author":"Roberto Mart\u00ednez-Beamonte","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2025.113955_bib67","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.bbalip.2012.02.007","article-title":"Regulation of plasma cholesterol esterification by sphingomyelin: effect of physiological variations of plasma sphingomyelin on lecithin-cholesterol acyltransferase activity","volume":"1821","author":"Subbaiah","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib68","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.1074\/jbc.271.8.4243","article-title":"The Influence of Sphingomyelin on the Structure and Function of Reconstituted High Density Lipoproteins","volume":"271","author":"Rye","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.isci.2025.113955_bib69","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0005-2760(88)90313-X","article-title":"Substrate specificity of human plasma lecithin-cholesterol acyltransferase towards molecular species of phosphatidylcholine in native plasma","volume":"963","author":"Subbaiah","year":"1988","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib70","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.bbalip.2012.02.007","article-title":"Reardon Regulation of plasma cholesterol esterification by sphingomyelin: Effect of physiological variations of plasma sphingomyelin on lecithin-cholesterol acyltransferase activity","volume":"1821","author":"Papasani Venkata Subbaiah","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib71","doi-asserted-by":"crossref","first-page":"19152","DOI":"10.1074\/jbc.271.32.19152","article-title":"Sphingomyelin Inhibits the Lecithin-Cholesterol Acyltransferase Reaction with Reconstituted High Density Lipoproteins by Decreasing Enzyme Binding","volume":"271","author":"Jonas","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.isci.2025.113955_bib72","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1194\/jlr.R200013-JLR200","article-title":"Carboxyl ester lipase: structure-function relationship and physiological role in lipoprotein metabolism and atherosclerosis","volume":"43","author":"Hui","year":"2002","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.isci.2025.113955_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106747","article-title":"Exposure to endocrine disrupting chemicals (EDCs) and cardiometabolic indices during pregnancy: The HOME Study","volume":"156","author":"Vuong","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.isci.2025.113955_bib74","doi-asserted-by":"crossref","first-page":"31417","DOI":"10.1074\/jbc.273.47.31417","article-title":"Transcriptional regulation of the human carboxyl ester lipase gene in exocrine pancreas. Evidence for a unique tissue-specific enhancer","volume":"273","author":"Lidberg","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.isci.2025.113955_bib75","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/j.1471-0528.2011.03266.x","article-title":"Dysregulated biomarkers induce distinct pathways in preterm birth","volume":"119","author":"Brou","year":"2012","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.isci.2025.113955_bib76","series-title":"R: A language and environment for statistical computing","year":"2022"},{"key":"10.1016\/j.isci.2025.113955_bib77","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3390\/metabo14040191","article-title":"Lipidome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys with Metabolic Dysfunction-Associated Steatotic Liver Disease","volume":"14","author":"Huneault HE","year":"2024","journal-title":"Metabolites"},{"key":"10.1016\/j.isci.2025.113955_bib78","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1038\/s41467-023-37269-3","article-title":"Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19","volume":"14","author":"Druzak","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2025.113955_bib79","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.aca.2018.08.002","article-title":"statTarget: A streamlined tool for signal drift correction and interpretations of quantitative mass spectrometry-based omics data","volume":"1036","author":"Hemi Luan","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.isci.2025.113955_bib80","series-title":"Hmisc: Harrell Miscellaneous","author":"F","year":"2023"},{"key":"10.1016\/j.isci.2025.113955_bib81","series-title":"ggraph: An Implementation of Grammar of Graphics for Graphs and Networks","author":"T","year":"2022"},{"key":"10.1016\/j.isci.2025.113955_bib82","series-title":"tidygraph: A Tidy API for Graph Manipulation","author":"T","year":"2022"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004225022163?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004225022163?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:25:22Z","timestamp":1783473922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004225022163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":82,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S2589004225022163"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2025.113955","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postpartum lipid dysregulation in African American women who experienced cardiometabolic complications of pregnancy","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2025.113955","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113955"}}