{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:49:10Z","timestamp":1791838150003,"version":"4.3.4"},"reference-count":80,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.isci.2026.116197","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T20:48:47Z","timestamp":1780174127000},"page":"116197","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mindfulness combined with cognitive motor dual task training in Parkinson\u2019s disease with mild cognitive impairment"],"prefix":"10.1016","volume":"29","author":[{"given":"Rui","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0250-1808","authenticated-orcid":false,"given":"Jing-Zhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Mao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben-xiang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2026.116197_bib1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S1474-4422(21)00030-2","article-title":"Challenges in the diagnosis of Parkinson's disease","volume":"20","author":"Tolosa","year":"2021","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/jpm15050172","article-title":"Redefining Non-Motor Symptoms in Parkinson's Disease","volume":"15","author":"Pe\u00f1a-Zelayeta","year":"2025","journal-title":"J. Personalized Med."},{"key":"10.1016\/j.isci.2026.116197_bib4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/mds.24893","article-title":"Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines","volume":"27","author":"Litvan","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib5","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1037\/0894-4105.19.4.520","article-title":"Cognitive impairment in preclinical Alzheimer's disease: a meta-analysis","volume":"19","author":"B\u00e4ckman","year":"2005","journal-title":"Neuropsychology"},{"key":"10.1016\/j.isci.2026.116197_bib6","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/nrneurol.2017.27","article-title":"Cognitive decline in Parkinson disease","volume":"13","author":"Aarsland","year":"2017","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib7","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41572-021-00280-3","article-title":"Parkinson disease-associated cognitive impairment","volume":"7","author":"Aarsland","year":"2021","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.isci.2026.116197_bib8","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1093\/brain\/awp245","article-title":"The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort","volume":"132","author":"Williams-Gray","year":"2009","journal-title":"Brain : a journal of neurology"},{"key":"10.1016\/j.isci.2026.116197_bib9","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3390\/bs11040054","article-title":"Treatment of Parkinson's Disease with Cognitive Impairment: Current Approaches and Future Directions","volume":"11","author":"Sun","year":"2021","journal-title":"Behav. Sci."},{"key":"10.1016\/j.isci.2026.116197_bib10","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1080\/13825585.2018.1513450","article-title":"The impact of cognitive interventions on cognitive symptoms in idiopathic Parkinson's disease: a systematic review. Neuropsychology, development, and cognition Section B","volume":"26","author":"Couture","year":"2019","journal-title":"Aging Neuropsychol. Cognit."},{"key":"10.1016\/j.isci.2026.116197_bib11","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/mds.26236","article-title":"Rivastigmine for mild cognitive impairment in Parkinson disease: a placebo-controlled study","volume":"30","author":"Mamikonyan","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib12","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1136\/jnnp-2018-318107","article-title":"Early use of donepezil against psychosis and cognitive decline in Parkinson's disease: a randomised controlled trial for 2 years","volume":"89","author":"Sawada","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1136\/jnnp.2008.144048","article-title":"A double-blind comparison of galantamine hydrobromide ER and placebo in Parkinson disease","volume":"80","author":"Grace","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib14","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/mds.26617","article-title":"Rasagiline for mild cognitive impairment in Parkinson's disease: A placebo-controlled trial","volume":"31","author":"Weintraub","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib15","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1176\/appi.neuropsych.15050118","article-title":"Cognitive Effects of Rasagiline in Mild-to-Moderate Stage Parkinson's Disease Without Dementia","volume":"29","author":"Frakey","year":"2017","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.isci.2026.116197_bib16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s12883-022-02699-x","article-title":"Memantine for the patients with mild cognitive impairment in Parkinson's disease: a pharmacological fMRI study","volume":"22","author":"Kawashima","year":"2022","journal-title":"BMC Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib17","article-title":"Cognitive training interventions for dementia and mild cognitive impairment in Parkinson's disease","volume":"2","author":"Orgeta","year":"2020","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib18","article-title":"Effects of physical exercise programs on cognitive function in Parkinson's disease patients: A systematic review of randomized controlled trials of the last 10 years","volume":"13","author":"da Silva","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2026.116197_bib19","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/1471-2377-11-90","article-title":"Single and dual task gait training in people with Parkinson's disease: a protocol for a randomised controlled trial","volume":"11","author":"Brauer","year":"2011","journal-title":"BMC Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib20","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1007\/s00415-023-11610-8","article-title":"Effects of motor-cognitive training on dual-task performance in people with Parkinson's disease: a systematic review and meta-analysis","volume":"270","author":"Johansson","year":"2023","journal-title":"J. Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib21","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1177\/1545968318763750","article-title":"Evidence for Differential Effects of 2 Forms of Exercise on Prefrontal Plasticity During Walking in Parkinson's Disease","volume":"32","author":"Maidan","year":"2018","journal-title":"Neurorehabil. Neural Repair"},{"key":"10.1016\/j.isci.2026.116197_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.archger.2024.105368","article-title":"Effect of dual-task training on balance in older adults: A systematic review and meta-analysis","volume":"121","author":"Ercan Yildiz","year":"2024","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.isci.2026.116197_bib23","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.gerinurse.2024.08.024","article-title":"Effects of the dual-task training program for Korean older adults with mild cognitive impairment in community","volume":"60","author":"Shin","year":"2024","journal-title":"Geriatric nursing (New York, NY)"},{"key":"10.1016\/j.isci.2026.116197_bib24","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3389\/fnagi.2019.00162","article-title":"Effects of Virtual Reality-Based Physical and Cognitive Training on Executive Function and Dual-Task Gait Performance in Older Adults With Mild Cognitive Impairment: A Randomized Control Trial","volume":"11","author":"Liao","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.isci.2026.116197_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.addbeh.2020.106465","article-title":"Third wave cognitive and behavioral processes and therapies for addictive behaviors: An introduction to the Special Issue","volume":"108","author":"Garey","year":"2020","journal-title":"Addict. Behav."},{"key":"10.1016\/j.isci.2026.116197_bib26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3233\/ADR-170031","article-title":"The Effects of Mindfulness on Older Adults with Mild Cognitive Impairment","volume":"1","author":"Wong","year":"2017","journal-title":"Journal of Alzheimer's disease reports"},{"key":"10.1016\/j.isci.2026.116197_bib27","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cpr.2017.10.011","article-title":"Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis","volume":"59","author":"Goldberg","year":"2018","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib28","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/pcn.12972","article-title":"Mindfulness practice alters brain connectivity in community-living elders with mild cognitive impairment","volume":"74","author":"Fam","year":"2020","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.isci.2026.116197_bib29","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.amjmed.2020.10.041","article-title":"Mindfulness and Cognitive Training Interventions in Mild Cognitive Impairment: Impact on Cognition and Mood","volume":"134","author":"Reynolds","year":"2021","journal-title":"Am. J. Med."},{"key":"10.1016\/j.isci.2026.116197_bib30","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1111\/jan.15720","article-title":"Effectiveness of mindfulness-based interventions on mental, cognitive outcomes and neuroplastic changes in older adults with mild cognitive impairment: A systematic review and meta-analysis","volume":"79","author":"Leow","year":"2023","journal-title":"J. Adv. Nurs."},{"key":"10.1016\/j.isci.2026.116197_bib31","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s11065-013-9230-9","article-title":"Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: working toward a theoretical model and evidence-based interventions","volume":"23","author":"Huckans","year":"2013","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib32","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/mds.26424","article-title":"MDS clinical diagnostic criteria for Parkinson's disease","volume":"30","author":"Postuma","year":"2015","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib33","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.isci.2026.116197_bib34","article-title":"Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations","volume":"2016","author":"Creavin","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib35","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s00415-025-13374-9","article-title":"Cognitive stimulation in Parkinson's disease with mild cognitive impairment","volume":"272","author":"Buonocore","year":"2025","journal-title":"J. Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib36","series-title":"Lovingkindness: The Revolutionary Art of Happiness","author":"Salzberg","year":"2004"},{"key":"10.1016\/j.isci.2026.116197_bib37","series-title":"Living a Healthy Life with Chronic Conditions: Self-Management of Heart Disease, Arthritis, Diabetes, Asthma, Bronchitis, Emphysema & Others","author":"Lorig","year":"2006"},{"key":"10.1016\/j.isci.2026.116197_bib38","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/gps.5279","article-title":"Does patient expectancy account for the cognitive and clinical benefits of mindfulness training in older adults?","volume":"35","author":"Haddad","year":"2020","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib39","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/mds.22340","article-title":"Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results","volume":"23","author":"Goetz","year":"2008","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib40","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib41","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/mds.23476","article-title":"Parkinson's disease sleep scale--validation of the revised version PDSS-2","volume":"26","author":"Trenkwalder","year":"2011","journal-title":"Movement disorders : official journal of the Movement Disorder Society"},{"key":"10.1016\/j.isci.2026.116197_bib42","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF02260863","article-title":"The development and validation of a short measure of functioning and well being for individuals with Parkinson's disease","volume":"4","author":"Peto","year":"1995","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.isci.2026.116197_bib43","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/15459683241290793","article-title":"Complex Exercises Improve Cognition in People With Parkinson's Disease and Freezing of Gait","volume":"39","author":"Silva-Batista","year":"2025","journal-title":"Neurorehabil. Neural Repair"},{"key":"10.1016\/j.isci.2026.116197_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/8032180","article-title":"Neural Correlates of Dual-Task Walking: Effects of Cognitive versus Motor Interference in Young Adults","volume":"2016","author":"Beurskens","year":"2016","journal-title":"Neural Plast."},{"key":"10.1016\/j.isci.2026.116197_bib45","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2024-086941","article-title":"Comparative effects of dual-task training versus combined exercise training in water and on land on patients with multiple sclerosis: a study protocol of a randomised factorial trial","volume":"15","author":"Nazary Soltan Ahmad","year":"2025","journal-title":"BMJ Open"},{"key":"10.1016\/j.isci.2026.116197_bib46","doi-asserted-by":"crossref","first-page":"359","DOI":"10.14283\/jpad.2022.16","article-title":"The Effects of Dual-Task Training on Cognitive and Physical Functions in Older Adults with Cognitive Impairment; A Systematic Review and Meta-Analysis","volume":"9","author":"Ali","year":"2022","journal-title":"The Journal of Prevention of Alzheimer's. Disease"},{"key":"10.1016\/j.isci.2026.116197_bib47","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/jclp.20237","article-title":"Mechanisms of mindfulness","volume":"62","author":"Shapiro","year":"2006","journal-title":"J. Clin. Psychol."},{"key":"10.1016\/j.isci.2026.116197_bib48","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1002\/hbm.24593","article-title":"A divergent breakdown of neurocognitive networks in Parkinson's Disease mild cognitive impairment","volume":"40","author":"Aracil-Bola\u00f1os","year":"2019","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.isci.2026.116197_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2022.104583","article-title":"Resting-state fMRI functional connectivity and mindfulness in clinical and non-clinical contexts: A review and synthesis","volume":"135","author":"Sezer","year":"2022","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib50","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/aphw.12188","article-title":"Mindfulness-Based Interventions for University Students: A Systematic Review and Meta-Analysis of Randomised Controlled Trials","volume":"12","author":"Dawson","year":"2020","journal-title":"Applied Psych. Health &. Well."},{"key":"10.1016\/j.isci.2026.116197_bib51","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1016\/j.clineuro.2013.10.002","article-title":"Mindfulness based intervention in Parkinson's disease leads to structural brain changes on MRI: a randomized controlled longitudinal trial","volume":"115","author":"Pickut","year":"2013","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.isci.2026.116197_bib52","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s11065-021-09519-y","article-title":"The Effect of Mindfulness-based Programs on Cognitive Function in Adults: A Systematic Review and Meta-analysis","volume":"32","author":"Whitfield","year":"2022","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib53","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S1474-4422(19)30285-6","article-title":"Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson's disease: a double-blind, randomised controlled trial","volume":"18","author":"van der Kolk","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib54","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1007\/s13311-020-00904-8","article-title":"Current Perspectives on Aerobic Exercise in People with Parkinson's Disease","volume":"17","author":"Schootemeijer","year":"2020","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.isci.2026.116197_bib55","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1177\/0269215507082341","article-title":"Multiple-task walking training in people with mild to moderate Parkinson's disease: a pilot study","volume":"22","author":"Canning","year":"2008","journal-title":"Clin. Rehabil."},{"key":"10.1016\/j.isci.2026.116197_bib56","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.apmr.2011.06.005","article-title":"A training program to improve gait while dual tasking in patients with Parkinson's disease: a pilot study","volume":"93","author":"Yogev-Seligmann","year":"2012","journal-title":"Archives of physical medicine and rehabilitation"},{"key":"10.1016\/j.isci.2026.116197_bib57","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.smhs.2021.10.003","article-title":"Dual-task training to improve cognitive impairment and walking function in Parkinson's disease patients: A brief review","volume":"3","author":"Zheng","year":"2021","journal-title":"Sports medicine and health science"},{"key":"10.1016\/j.isci.2026.116197_bib58","doi-asserted-by":"crossref","DOI":"10.5498\/wjp.v15.i4.103827","article-title":"Effects of exercise-cognitive dual-task training on elderly patients with cognitive frailty and depression","volume":"15","author":"Zhou","year":"2025","journal-title":"World J. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib59","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1589\/jpts.26.359","article-title":"The Effect of Motor Dual-task Balance Training on Balance and Gait of Elderly Women","volume":"26","author":"Shin","year":"2014","journal-title":"J. Phys. Ther. Sci."},{"key":"10.1016\/j.isci.2026.116197_bib60","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/NPT.0000000000000090","article-title":"Motor-Cognitive Dual-Task Training in Persons With Neurologic Disorders: A Systematic Review","volume":"39","author":"Fritz","year":"2015","journal-title":"J. Neurol. Phys. Ther."},{"key":"10.1016\/j.isci.2026.116197_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/7109052","article-title":"Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson's Disease","volume":"2016","author":"Dissanayaka","year":"2016","journal-title":"Parkinson's disease"},{"key":"10.1016\/j.isci.2026.116197_bib62","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1001\/jamaneurol.2019.0534","article-title":"Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease: A Randomized Clinical Trial","volume":"76","author":"Kwok","year":"2019","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.isci.2026.116197_bib63","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jad.2022.08.032","article-title":"Association between frailty and cognitive function in older Chinese people: A moderated mediation of social relationships and depressive symptoms","volume":"316","author":"Ma","year":"2022","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijnurstu.2024.104776","article-title":"Dual-task training in older adults with cognitive impairment: A meta-analysis and trial sequential analysis of randomized controlled trials","volume":"155","author":"Ye","year":"2024","journal-title":"Int. J. Nurs. Stud."},{"key":"10.1016\/j.isci.2026.116197_bib65","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1017\/S1041610215000915","article-title":"Relationship between dual task walking, cognition, and depression in oldest old people","volume":"28","author":"Ansai","year":"2016","journal-title":"International psychogeriatrics"},{"key":"10.1016\/j.isci.2026.116197_bib66","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/jgs.70154","article-title":"Effects of Mindfulness Training on Depression and Cognition in Older People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis","volume":"74","author":"V\u00e1squez-Carrasco","year":"2025","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.isci.2026.116197_bib67","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/mds.28345","article-title":"Stress and Mindfulness in Parkinson's Disease: Clinical Effects and Potential Underlying Mechanisms","volume":"36","author":"van der Heide","year":"2021","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib68","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nrn3916","article-title":"The neuroscience of mindfulness meditation","volume":"16","author":"Tang","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.isci.2026.116197_bib69","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.neubiorev.2014.03.016","article-title":"Is meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners","volume":"43","author":"Fox","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.isci.2026.116197_bib70","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1002\/mds.28009","article-title":"Randomized, Controlled Trial of Exercise on Objective and Subjective Sleep in Parkinson's Disease","volume":"35","author":"Amara","year":"2020","journal-title":"Mov. Disord."},{"key":"10.1016\/j.isci.2026.116197_bib71","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1001\/jamainternmed.2014.8081","article-title":"Mindfulness meditation and improvement in sleep quality and daytime impairment among older adults with sleep disturbances: a randomized clinical trial","volume":"175","author":"Black","year":"2015","journal-title":"JAMA Intern. Med."},{"key":"10.1016\/j.isci.2026.116197_bib72","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.genhosppsych.2021.09.004","article-title":"A mindfulness meditation mobile app improves depression and anxiety in adults with sleep disturbance: Analysis from a randomized controlled trial","volume":"73","author":"Huberty","year":"2021","journal-title":"Gen. Hosp. Psychiatry"},{"key":"10.1016\/j.isci.2026.116197_bib73","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1080\/01616412.2023.2258038","article-title":"Mild cognitive impairment in patients with Parkinson's disease and the analysis of associated factors","volume":"45","author":"Kobak Tur","year":"2023","journal-title":"Neurol. Res."},{"key":"10.1016\/j.isci.2026.116197_bib74","article-title":"Aquatic Dual-Task Training and Its Relation to Motor Functions, Activities of Daily Living, and Quality of Life of Individuals With Parkinson's Disease: A Randomized Clinical Trial","volume":"16","author":"da Silva","year":"2023","journal-title":"Health Serv. Insights"},{"key":"10.1016\/j.isci.2026.116197_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2019.116559","article-title":"Asymmetric dynamic center-of-pressure in Parkinson's disease","volume":"408","author":"Shin","year":"2020","journal-title":"Journal of the neurological sciences"},{"key":"10.1016\/j.isci.2026.116197_bib76","doi-asserted-by":"crossref","first-page":"S548","DOI":"10.1002\/mds.22062","article-title":"Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease","volume":"23","author":"Obeso","year":"2008","journal-title":"Movement disorders : official journal of the Movement Disorder Society"},{"key":"10.1016\/j.isci.2026.116197_bib77","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s00702-024-02813-y","article-title":"Neuroplasticity in Parkinson's disease","volume":"131","author":"Popescu","year":"2024","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.isci.2026.116197_bib78","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.gaitpost.2023.07.277","article-title":"Cognitive-motor dual-task interference in Alzheimer's disease, Parkinson's disease, and prodromal neurodegeneration: A scoping review","volume":"105","author":"Longhurst","year":"2023","journal-title":"Gait Posture"},{"key":"10.1016\/j.isci.2026.116197_bib79","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.3758\/s13415-020-00828-y","article-title":"Mindfulness meditation alters neural activity underpinning working memory during tactile distraction","volume":"20","author":"Wang","year":"2020","journal-title":"Cogn. Affect. Behav. Neurosci."},{"key":"10.1016\/j.isci.2026.116197_bib80","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/a-2239-1936","article-title":"Mapping the Current Research on Mindfulness Interventions for Individuals with Cerebral Palsy: A Scoping Review","volume":"55","author":"Tedeschi","year":"2024","journal-title":"Neuropediatrics"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226015725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226015725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:36:25Z","timestamp":1791837385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004226015725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":80,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2589004226015725"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2026.116197","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mindfulness combined with cognitive motor dual task training in Parkinson\u2019s disease with mild cognitive impairment","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2026.116197","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116197"}}