{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T18:22:54Z","timestamp":1794248574639,"version":"4.9.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000016","name":"U.S. Department of Health and Human Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000016","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","award":["HHSN272201800013C"],"award-info":[{"award-number":["HHSN272201800013C"]}],"id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.isci.2026.116874","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T19:11:35Z","timestamp":1784833895000},"page":"116874","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genomics in containment: BSL-4-compatible workflows enable high-resolution genomic and transcriptomic analyses of Risk Group 4 viruses"],"prefix":"10.1016","volume":"29","author":[{"given":"Lirong","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew P.","family":"Platt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Drawbaugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Kocher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Holbrook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3928-3733","authenticated-orcid":false,"given":"Monika","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2026.116874_bib1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3390\/v14030600","article-title":"Next-Generation Sequencing for Confronting Virus Pandemics","volume":"14","author":"Quer","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.isci.2026.116874_bib2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41564-018-0296-2","article-title":"Tracking virus outbreaks in the twenty-first century","volume":"4","author":"Grubaugh","year":"2019","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.isci.2026.116874_bib3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.6026\/97320630019345","article-title":"Dangerous Risk Group-4 (RG-4) emergent viruses","volume":"19","author":"Sinnott","year":"2023","journal-title":"Bioinformation"},{"key":"10.1016\/j.isci.2026.116874_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3390\/pathogens11020271","article-title":"Methods of Inactivation of Highly Pathogenic Viruses for Molecular, Serology or Vaccine Development Purposes","volume":"11","author":"Elveborg","year":"2022","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib5","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.3201\/eid2207.160233","article-title":"Effective Chemical Inactivation of Ebola Virus","volume":"22","author":"Haddock","year":"2016","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.isci.2026.116874_bib6","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3390\/pathogens12070952","article-title":"Art of the Kill: Designing and Testing Viral Inactivation Procedures for Highly Pathogenic Negative Sense RNA Viruses","volume":"12","author":"Olejnik","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib7","doi-asserted-by":"crossref","first-page":"114262","DOI":"10.1016\/j.jviromet.2021.114262","article-title":"Use of guanidine thiocyanate-based nucleic acid extraction buffers to inactivate poliovirus in potentially infectious materials","volume":"297","author":"Honeywood","year":"2021","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib8","doi-asserted-by":"crossref","first-page":"114287","DOI":"10.1016\/j.jviromet.2021.114287","article-title":"Evaluation of henipavirus chemical inactivation methods for the safe removal of samples from the high-containment PC4 laboratory","volume":"298","author":"Edwards","year":"2021","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib9","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.cell.2015.05.002","article-title":"Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets","volume":"161","author":"Macosko","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.116874_bib10","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.cell.2015.04.044","article-title":"Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells","volume":"161","author":"Klein","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.116874_bib11","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3390\/pathogens13020167","article-title":"Preservation of scRNA-Seq Libraries Using Existing Inactivation Protocols","volume":"13","author":"Sturdevant","year":"2024","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib12","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.cell.2020.10.002","article-title":"Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics","volume":"183","author":"Kotliar","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.116874_bib13","doi-asserted-by":"crossref","first-page":"62","DOI":"10.3390\/pathogens13010062","article-title":"Heat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality","volume":"13","author":"Hume","year":"2024","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib14","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3390\/pathogens12020342","article-title":"Establishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers","volume":"12","author":"Olejnik","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib15","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/nprot.2017.066","article-title":"Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples","volume":"12","author":"Quick","year":"2017","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.isci.2026.116874_bib16","doi-asserted-by":"crossref","first-page":"e0249224","DOI":"10.1128\/spectrum.02492-24","article-title":"Development of a culture-independent whole-genome sequencing of Nipah virus using the MinION Oxford Nanopore platform","volume":"13","author":"Rahman","year":"2025","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.isci.2026.116874_bib17","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nature16996","article-title":"Real-time, portable genome sequencing for Ebola surveillance","volume":"530","author":"Quick","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.isci.2026.116874_bib18","doi-asserted-by":"crossref","first-page":"e0098624","DOI":"10.1128\/spectrum.00986-24","article-title":"Direct genome sequencing of respiratory viruses from low viral load clinical specimens using the target capture sequencing technology","volume":"12","author":"Takemae","year":"2024","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.isci.2026.116874_bib19","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3390\/cells12030493","article-title":"Targeted Sequencing Approach and Its Clinical Applications for the Molecular Diagnosis of Human Diseases","volume":"12","author":"Pei","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.isci.2026.116874_bib20","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3390\/pathogens13040275","article-title":"Hybrid-Capture Target Enrichment in Human Pathogens: Identification, Evolution, Biosurveillance, and Genomic Epidemiology","volume":"13","author":"Quek","year":"2024","journal-title":"Pathogens"},{"key":"10.1016\/j.isci.2026.116874_bib21","doi-asserted-by":"crossref","first-page":"e00039-15","DOI":"10.1128\/mSystems.00039-15","article-title":"A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses","volume":"1","author":"Moser","year":"2016","journal-title":"mSystems"},{"key":"10.1016\/j.isci.2026.116874_bib22","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/bfgp\/elx033","article-title":"The utility and perspectives of NGS-based methods in BSL-3 and BSL-4 laboratory - sequencing and analysis strategies","volume":"17","author":"Wolkowicz","year":"2018","journal-title":"Brief. Funct. Genomics"},{"key":"10.1016\/j.isci.2026.116874_bib23","first-page":"S292","article-title":"Next Generation Sequencing and Bioinformatics Methodologies for Infectious Disease Research and Public Health: Approaches, Applications, and Considerations for Development of Laboratory Capacity","volume":"221","author":"Maljkovic Berry","year":"2020","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.isci.2026.116874_bib24","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nmeth.3629","article-title":"Fixed single-cell transcriptomic characterization of human radial glial diversity","volume":"13","author":"Thomsen","year":"2016","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jviromet.2004.03.015","article-title":"Virus inactivation by nucleic acid extraction reagents","volume":"119","author":"Blow","year":"2004","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib26","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.3390\/v16091354","article-title":"Inactivation Validation of Ebola, Marburg, and Lassa Viruses in AVL and Ethanol-Treated Viral Cultures","volume":"16","author":"Cutts","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.isci.2026.116874_bib27","doi-asserted-by":"crossref","first-page":"968","DOI":"10.3390\/v13060968","article-title":"Validation of Inactivation Methods for Arenaviruses","volume":"13","author":"Olschewski","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.isci.2026.116874_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jviromet.2015.07.002","article-title":"Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus","volume":"223","author":"Kumar","year":"2015","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib29","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.1128\/JCM.01449-15","article-title":"Buffer AVL Alone Does Not Inactivate Ebola Virus in a Representative Clinical Sample Type","volume":"53","author":"Smither","year":"2015","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.isci.2026.116874_bib30","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1128\/JCM.00346-16","article-title":"Rapid Bedside Inactivation of Ebola Virus for Safe Nucleic Acid Tests","volume":"54","author":"Rosenstierne","year":"2016","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.isci.2026.116874_bib31","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1128\/jcm.28.3.495-503.1990","article-title":"Rapid and simple method for purification of nucleic acids","volume":"28","author":"Boom","year":"1990","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.isci.2026.116874_bib32","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.isci.2026.116874_bib33","doi-asserted-by":"crossref","first-page":"gkae1186","DOI":"10.1093\/nar\/gkae1186","article-title":"A comprehensive analysis framework for evaluating commercial single-cell RNA sequencing technologies","volume":"53","author":"De Simone","year":"2025","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.isci.2026.116874_bib34","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1038\/s42003-024-07043-2","article-title":"snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives","volume":"7","author":"Wang","year":"2024","journal-title":"Commun. Biol."},{"key":"10.1016\/j.isci.2026.116874_bib35","doi-asserted-by":"crossref","first-page":"lqaf215","DOI":"10.1093\/nargab\/lqaf215","article-title":"Evaluating the practical aspects and performance of commercial single-cell RNA sequencing technologies","volume":"8","author":"Elz","year":"2026","journal-title":"NAR Genomics and Bioinformatics"},{"key":"10.1016\/j.isci.2026.116874_bib36","doi-asserted-by":"crossref","first-page":"101582","DOI":"10.1016\/j.nmni.2025.101582","article-title":"Ferritin's role in infectious diseases: Exploring pathogenic mechanisms and clinical implications","volume":"65","author":"Liao","year":"2025","journal-title":"New Microbes New Infect."},{"key":"10.1016\/j.isci.2026.116874_bib37","doi-asserted-by":"crossref","first-page":"102778","DOI":"10.1016\/j.jaut.2021.102778","article-title":"Ferritin - from iron, through inflammation and autoimmunity, to COVID-19","volume":"126","author":"Mahroum","year":"2022","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.isci.2026.116874_bib38","doi-asserted-by":"crossref","first-page":"589","DOI":"10.3390\/microorganisms8040589","article-title":"Ferritin: An Inflammatory Player Keeping Iron at the Core of Pathogen-Host Interactions","volume":"8","author":"Moreira","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.isci.2026.116874_bib39","doi-asserted-by":"crossref","first-page":"e2531","DOI":"10.1002\/rmv.2531","article-title":"Ferritin: Significance in viral infections","volume":"34","author":"Zhao","year":"2024","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.isci.2026.116874_bib40","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5152\/eajm.2013.22","article-title":"Can serum ferritin level predict disease severity in patients with crimean-congo hemorrhagic Fever?","volume":"45","author":"Metanat","year":"2013","journal-title":"Eurasian J. Med."},{"key":"10.1016\/j.isci.2026.116874_bib41","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/978-1-0716-4256-6_27","article-title":"Droplet-Based Single-Cell 3' mRNA Sequencing of Marburg Virus-Infected Samples","volume":"2877","author":"Meyer","year":"2025","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.isci.2026.116874_bib42","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.3389\/fmicb.2018.02924","article-title":"Hybrid Capture-Based Next Generation Sequencing and Its Application to Human Infectious Diseases","volume":"9","author":"Gaudin","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.isci.2026.116874_bib43","doi-asserted-by":"crossref","first-page":"S635","DOI":"10.1093\/infdis\/jiad374","article-title":"Clinical and Immunologic Correlates of Vasodilatory Shock Among Ebola Virus-Infected Nonhuman Primates in a Critical Care Model","volume":"228","author":"Stein","year":"2023","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.isci.2026.116874_bib44","doi-asserted-by":"crossref","first-page":"105987","DOI":"10.1016\/j.antiviral.2024.105987","article-title":"Characterization of therapeutic antibody efficacy against multiple SARS-CoV-2 variants in the hamster model","volume":"230","author":"Cong","year":"2024","journal-title":"Antiviral Res."},{"key":"10.1016\/j.isci.2026.116874_bib45","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1016\/j.cell.2019.05.031","article-title":"Comprehensive Integration of Single-Cell Data","volume":"177","author":"Stuart","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.116874_bib46","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1093\/bioinformatics\/bty191","article-title":"Minimap2: pairwise alignment for nucleotide sequences","volume":"34","author":"Li","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.isci.2026.116874_bib47","doi-asserted-by":"crossref","first-page":"giab008","DOI":"10.1093\/gigascience\/giab008","article-title":"Twelve years of SAMtools and BCFtools","volume":"10","author":"Danecek","year":"2021","journal-title":"GigaScience"},{"key":"10.1016\/j.isci.2026.116874_bib48","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with Burrows-Wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.isci.2026.116874_bib49","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1101\/gr.107524.110","article-title":"The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data","volume":"20","author":"McKenna","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.isci.2026.116874_bib50","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J. Comput. Biol."},{"key":"10.1016\/j.isci.2026.116874_bib51","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2026.116874_bib52","doi-asserted-by":"crossref","first-page":"11189","DOI":"10.1093\/nar\/gks918","article-title":"LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets","volume":"40","author":"Wilm","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.isci.2026.116874_bib53","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13059-018-1618-7","article-title":"An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar","volume":"20","author":"Grubaugh","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.isci.2026.116874_bib54","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s13059-022-02823-7","article-title":"Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing","volume":"23","author":"Alonge","year":"2022","journal-title":"Genome Biol."},{"key":"10.1016\/j.isci.2026.116874_bib55","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/bioinformatics\/btx699","article-title":"Mosdepth: quick coverage calculation for genomes and exomes","volume":"34","author":"Pedersen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.isci.2026.116874_bib56","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1471-2105-13-134","article-title":"Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction","volume":"13","author":"Ye","year":"2012","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.isci.2026.116874_bib57","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.116874_bib58","doi-asserted-by":"crossref","first-page":"14049","DOI":"10.1038\/ncomms14049","article-title":"Massively parallel digital transcriptional profiling of single cells","volume":"8","author":"Zheng","year":"2017","journal-title":"Nat. Commun."}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226022522?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226022522?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T17:56:34Z","timestamp":1794246994000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004226022522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2589004226022522"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2026.116874","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genomics in containment: BSL-4-compatible workflows enable high-resolution genomic and transcriptomic analyses of Risk Group 4 viruses","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2026.116874","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116874"}}